메뉴 건너뛰기




Volumn 4, Issue 145, 2012, Pages

Reversal of paralysis and reduced inflammation from peripheral administration of β-amyloid in TH1 and TH17 versions of experimental autoimmune encephalomyelitis

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; CD19 ANTIGEN; CD4 ANTIGEN; CD69 ANTIGEN; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 12P70; INTERLEUKIN 17; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 6; L SELECTIN; MONOCYTE CHEMOTACTIC PROTEIN 1; TRANSCRIPTION FACTOR FOXP3;

EID: 84864553199     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.3004145     Document Type: Article
Times cited : (82)

References (60)
  • 4
    • 0037041426 scopus 로고    scopus 로고
    • Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo
    • D.M. Walsh, I. Klyubin, J. V. Fadeeva, W. K. Cullen, R.Anwyl, M. S. Wolfe, M. J. Rowan, D. J. Selkoe, Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo. Nature 416, 535-539 (2002).
    • (2002) Nature , vol.416 , pp. 535-539
    • Walsh, D.M.1    Klyubin, I.2    Fadeeva, J.V.3    Cullen, W.K.4    Anwyl, R.5    Wolfe, M.S.6    Rowan, M.J.7    Selkoe, D.J.8
  • 5
    • 0031921466 scopus 로고    scopus 로고
    • Mutant genes in familial Alzheimer 's disease and transgenic models
    • D. L. Price, S. S. Sisodia, Mutant genes in familial Alzheimer 's disease and transgenic models. Annu. Rev. Neurosci. 21, 479-505 (1998).
    • (1998) Annu. Rev. Neurosci. , vol.21 , pp. 479-505
    • Price, D.L.1    Sisodia, S.S.2
  • 6
    • 32344440522 scopus 로고    scopus 로고
    • Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease
    • A. R. Simard, D. Soulet, G. Gowing, J. P. Julien, S. Rivest, Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease. Neuron 49, 489-502 (2006).
    • (2006) Neuron , vol.49 , pp. 489-502
    • Simard, A.R.1    Soulet, D.2    Gowing, G.3    Julien, J.P.4    Rivest, S.5
  • 7
    • 0024436506 scopus 로고
    • Relationship of microglia and astrocytes to amyloid deposits of Alzheimer disease
    • S. Itagaki, P. L. McGeer, H. Akiyama, S. Zhu, D. Selkoe, Relationship of microglia and astrocytes to amyloid deposits of Alzheimer disease. J. Neuroimmunol. 24, 173-182 (1989).
    • (1989) J. Neuroimmunol. , vol.24 , pp. 173-182
    • Itagaki, S.1    McGeer, P.L.2    Akiyama, H.3    Zhu, S.4    Selkoe, D.5
  • 9
    • 33748471099 scopus 로고    scopus 로고
    • Inflammation in Alzheimer disease: Driving force, bystander or beneficial response?
    • T. Wyss-Coray, Inflammation in Alzheimer disease: Driving force, bystander or beneficial response? Nat. Med. 12, 1005-1015 (2006).
    • (2006) Nat. Med. , vol.12 , pp. 1005-1015
    • Wyss-Coray, T.1
  • 11
    • 0242268945 scopus 로고    scopus 로고
    • Immunotherapeutic approaches to Alzheimer's disease
    • A. Monsonego, H. L. Weiner, Immunotherapeutic approaches to Alzheimer's disease. Science 302, 834-838 (2003).
    • (2003) Science , vol.302 , pp. 834-838
    • Monsonego, A.1    Weiner, H.L.2
  • 12
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
    • J. Hardy, D. J. Selkoe, The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics. Science 297, 353-356 (2002).
    • (2002) Science , vol.297 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 13
    • 33646384419 scopus 로고    scopus 로고
    • Immunology and immunotherapy of Alzheimer's disease
    • H. L. Weiner, D. Frenkel, Immunology and immunotherapy of Alzheimer's disease. Nat. Rev. Immunol. 6, 404-416 (2006).
    • (2006) Nat. Rev. Immunol. , vol.6 , pp. 404-416
    • Weiner, H.L.1    Frenkel, D.2
  • 15
    • 57649221135 scopus 로고    scopus 로고
    • Amyloid precursor protein trafficking, processing, and function
    • G. Thinakaran, E. H. Koo, Amyloid precursor protein trafficking, processing, and function. J. Biol. Chem. 283, 29615-29619 (2008).
    • (2008) J. Biol. Chem. , vol.283 , pp. 29615-29619
    • Thinakaran, G.1    Koo, E.H.2
  • 17
    • 0037155581 scopus 로고    scopus 로고
    • Brain to plasma amyloid-β efflux: A measure of brain amyloid burden in a mouse model of Alzheimer's disease
    • R. B. DeMattos, K. R. Bales, D. J. Cummins, S. M. Paul, D. M. Holtzman, Brain to plasma amyloid-β efflux: A measure of brain amyloid burden in a mouse model of Alzheimer's disease. Science 295, 2264-2267 (2002).
    • (2002) Science , vol.295 , pp. 2264-2267
    • DeMattos, R.B.1    Bales, K.R.2    Cummins, D.J.3    Paul, S.M.4    Holtzman, D.M.5
  • 19
    • 33644607018 scopus 로고    scopus 로고
    • Multiple sclerosis - The plaque and its pathogenesis
    • E. M. Frohman, M. K. Racke, C. S. Raine, Multiple sclerosis - The plaque and its pathogenesis. N. Engl. J. Med. 354, 942-955 (2006).
    • (2006) N. Engl. J. Med. , vol.354 , pp. 942-955
    • Frohman, E.M.1    Racke, M.K.2    Raine, C.S.3
  • 21
    • 0031002545 scopus 로고    scopus 로고
    • Axonal damage in acute multiple sclerosis lesions
    • B. Ferguson, M. K. Matyszak, M. M. Esiri, V. H. Perry, Axonal damage in acute multiple sclerosis lesions. Brain 120 (Pt. 3), 393-399 (1997).
    • (1997) Brain , vol.120 , Issue.PART 3 , pp. 393-399
    • Ferguson, B.1    Matyszak, M.K.2    Esiri, M.M.3    Perry, V.H.4
  • 24
    • 0025246367 scopus 로고
    • The T lymphocyte in experimental allergic encephalomyelitis
    • S. S. Zamvil, L. Steinman, The T lymphocyte in experimental allergic encephalomyelitis. Annu. Rev. Immunol. 8, 579-621 (1990).
    • (1990) Annu. Rev. Immunol. , vol.8 , pp. 579-621
    • Zamvil, S.S.1    Steinman, L.2
  • 25
    • 20844454381 scopus 로고    scopus 로고
    • Blocking adhesion molecules as therapy for multiple sclerosis: Natalizumab
    • L. Steinman, Blocking adhesion molecules as therapy for multiple sclerosis: Natalizumab. Nat. Rev. Drug Discov. 4, 510-518 (2005).
    • (2005) Nat. Rev. Drug Discov. , vol.4 , pp. 510-518
    • Steinman, L.1
  • 26
    • 77951073508 scopus 로고    scopus 로고
    • Mechanism of action of oral fingolimod (FTY720) in multiple sclerosis
    • J. Chun, H. P. Hartung, Mechanism of action of oral fingolimod (FTY720) in multiple sclerosis. Clin. Neuropharmacol. 33, 91-101 (2010).
    • (2010) Clin. Neuropharmacol. , vol.33 , pp. 91-101
    • Chun, J.1    Hartung, H.P.2
  • 28
    • 0023782375 scopus 로고
    • Expression of the histocompatibility glycoprotein HLA-DR in neurological disease
    • P. L. McGeer, S. Itagaki, E. G. McGeer, Expression of the histocompatibility glycoprotein HLA-DR in neurological disease. Acta Neuropathol. 76, 550-557 (1988).
    • (1988) Acta Neuropathol. , vol.76 , pp. 550-557
    • McGeer, P.L.1    Itagaki, S.2    McGeer, E.G.3
  • 32
    • 69349093225 scopus 로고    scopus 로고
    • Interleukin-17 and type 17 helper T cells
    • P. Miossec, T. Korn, V. K. Kuchroo, Interleukin-17 and type 17 helper T cells. N. Engl. J. Med. 361, 888-898 (2009).
    • (2009) N. Engl. J. Med. , vol.361 , pp. 888-898
    • Miossec, P.1    Korn, T.2    Kuchroo, V.K.3
  • 33
    • 33846966636 scopus 로고    scopus 로고
    • A brief history of TH17, the first major revision in the TH1/TH2 hypothesis of T cell-mediated tissue damage
    • L. Steinman, A brief history of TH17, the first major revision in the TH1/TH2 hypothesis of T cell-mediated tissue damage. Nat. Med. 13, 139-145 (2007).
    • (2007) Nat. Med. , vol.13 , pp. 139-145
    • Steinman, L.1
  • 36
    • 24644435506 scopus 로고    scopus 로고
    • Nasal vaccination with a proteosome-based adjuvant and glatiramer acetate clears β-amyloid in a mouse model of Alzheimer disease
    • D. Frenkel, R. Maron, D. S. Burt, H. L. Weiner, Nasal vaccination with a proteosome-based adjuvant and glatiramer acetate clears β-amyloid in a mouse model of Alzheimer disease. J. Clin. Invest. 115, 2423-2433 (2005).
    • (2005) J. Clin. Invest. , vol.115 , pp. 2423-2433
    • Frenkel, D.1    Maron, R.2    Burt, D.S.3    Weiner, H.L.4
  • 38
    • 0037393454 scopus 로고    scopus 로고
    • Neuropathology of human Alzheimer disease after immunization with amyloid-β peptide: A case report
    • J. A. Nicoll, D. Wilkinson, C. Holmes, P. Steart, H. Markham, R. O. Weller, Neuropathology of human Alzheimer disease after immunization with amyloid-β peptide: A case report. Nat. Med. 9, 448-452 (2003).
    • (2003) Nat. Med. , vol.9 , pp. 448-452
    • Nicoll, J.A.1    Wilkinson, D.2    Holmes, C.3    Steart, P.4    Markham, H.5    Weller, R.O.6
  • 39
    • 77954563548 scopus 로고    scopus 로고
    • Current views on the roles of Th1 and Th17 cells in experimental autoimmune encephalomyelitis
    • M. El-behi, A. Rostami, B. Ciric, Current views on the roles of Th1 and Th17 cells in experimental autoimmune encephalomyelitis. J. Neuroimmune Pharmacol. 5, 189-197 (2010).
    • (2010) J. Neuroimmune Pharmacol. , vol.5 , pp. 189-197
    • El-behi, M.1    Rostami, A.2    Ciric, B.3
  • 40
    • 34248647881 scopus 로고    scopus 로고
    • Active induction of experimental allergic encephalomyelitis
    • I. M. Stromnes, J. M. Goverman, Active induction of experimental allergic encephalomyelitis. Nat. Protoc. 1, 1810-1819 (2006).
    • (2006) Nat. Protoc. , vol.1 , pp. 1810-1819
    • Stromnes, I.M.1    Goverman, J.M.2
  • 44
    • 45849153869 scopus 로고    scopus 로고
    • Coordination of early protective immunity to viral infection by regulatory T cells
    • J. M. Lund, L. Hsing, T. T. Pham, A. Y. Rudensky, Coordination of early protective immunity to viral infection by regulatory T cells. Science 320, 1220-1224 (2008).
    • (2008) Science , vol.320 , pp. 1220-1224
    • Lund, J.M.1    Hsing, L.2    Pham, T.T.3    Rudensky, A.Y.4
  • 46
    • 0027195933 scopus 로고
    • Seeding "one-dimensional crystallization" of amyloid: A pathogenic mechanism in Alzheimer's disease and scrapie?
    • J. T. Jarrett, P. T. Lansbury Jr., Seeding "one-dimensional crystallization" of amyloid: A pathogenic mechanism in Alzheimer's disease and scrapie? Cell 73, 1055-1058 (1993).
    • (1993) Cell , vol.73 , pp. 1055-1058
    • Jarrett, J.T.1    Lansbury Jr., P.T.2
  • 47
    • 0028903933 scopus 로고
    • Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo
    • N. Zamzami, P. Marchetti, M. Castedo, C. Zanin, J. L. Vayssière, P. X. Petit, G. Kroemer, Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo. J. Exp. Med. 181, 1661-1672 (1995).
    • (1995) J. Exp. Med. , vol.181 , pp. 1661-1672
    • Zamzami, N.1    Marchetti, P.2    Castedo, M.3    Zanin, C.4    Vayssière, J.L.5    Petit, P.X.6    Kroemer, G.7
  • 52
    • 0029957071 scopus 로고    scopus 로고
    • Interferon-g confers resistance to experimental allergic encephalomyelitis
    • M. Krakowski, T. Owens, Interferon-g confers resistance to experimental allergic encephalomyelitis. Eur. J. Immunol. 26, 1641-1646 (1996).
    • (1996) Eur. J. Immunol. , vol.26 , pp. 1641-1646
    • Krakowski, M.1    Owens, T.2
  • 53
    • 0025293228 scopus 로고
    • Suppression of experimental allergic encephalomyelitis by intraventricular administration of interferon-gamma in Lewis rats
    • J. A. Voorthuis, B. M. Uitdehaag, C. J. De Groot, P. H. Goede, P. H. van der Meide, C. D. Dijkstra, Suppression of experimental allergic encephalomyelitis by intraventricular administration of interferon-gamma in Lewis rats. Clin. Exp. Immunol. 81, 183-188 (1990).
    • (1990) Clin. Exp. Immunol. , vol.81 , pp. 183-188
    • Voorthuis, J.A.1    Uitdehaag, B.M.2    De Groot, C.J.3    Goede, P.H.4    Van Der Meide, P.H.5    Dijkstra, C.D.6
  • 54
    • 0033571331 scopus 로고    scopus 로고
    • IFN-γ is critical to the control of murine autoimmune encephalomyelitis and regulates both in the periphery and in the target tissue: A possible role for nitric oxide
    • D. O. Willenborg, S. A. Fordham, M. A. Staykova, I. A. Ramshaw, W. B. Cowden, IFN-γ is critical to the control of murine autoimmune encephalomyelitis and regulates both in the periphery and in the target tissue: A possible role for nitric oxide. J. Immunol. 163, 5278-5286 (1999).
    • (1999) J. Immunol. , vol.163 , pp. 5278-5286
    • Willenborg, D.O.1    Fordham, S.A.2    Staykova, M.A.3    Ramshaw, I.A.4    Cowden, W.B.5
  • 58
    • 79956125257 scopus 로고    scopus 로고
    • Origins of CD4+ effector and central memory T cells
    • M. Pepper, M. K. Jenkins, Origins of CD4+ effector and central memory T cells. Nat. Immunol. 12, 467-471 (2011).
    • (2011) Nat. Immunol. , vol.12 , pp. 467-471
    • Pepper, M.1    Jenkins, M.K.2
  • 59
    • 0037203825 scopus 로고    scopus 로고
    • Nerve inflammation halts trial for Alzheimer's drug
    • E. Check, Nerve inflammation halts trial for Alzheimer's drug. Nature 415, 462 (2002).
    • (2002) Nature , vol.415 , pp. 462
    • Check, E.1
  • 60
    • 0035503984 scopus 로고    scopus 로고
    • Spectral compensation for flow cytometry: Visualization artifacts, limitations, and caveats
    • M. Roederer, Spectral compensation for flow cytometry: Visualization artifacts, limitations, and caveats. Cytometry 45, 194-205 (2001).
    • (2001) Cytometry , vol.45 , pp. 194-205
    • Roederer, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.