메뉴 건너뛰기




Volumn 45, Issue 3, 2011, Pages 351-358

An investigation of the effects of MitoQ on human peripheral mononuclear cells

Author keywords

DNA damage; MitoQ; oxidative stress; T cell immonosenescence

Indexed keywords

GLUTATHIONE; HYDROGEN PEROXIDE; MITOQ; UBIQUINONE DERIVATIVE; UNCLASSIFIED DRUG;

EID: 79551623771     PISSN: 10715762     EISSN: 10292470     Source Type: Journal    
DOI: 10.3109/10715762.2010.532497     Document Type: Article
Times cited : (18)

References (23)
  • 4
    • 0015319592 scopus 로고
    • The biological clock: The mitochondria?
    • Harman D. The biological clock: the mitochondria? J Am Geriatr Soc 1972;20:145-147.
    • (1972) J Am Geriatr Soc , vol.20 , pp. 145-147
    • Harman, D.1
  • 6
    • 0029102337 scopus 로고
    • An investigation of in vivo antioxidant status, mutation and DNA repair capacity in human lymphocytes as a function of age
    • Barnett YA, King CM. An investigation of in vivo antioxidant status, mutation and DNA repair capacity in human lymphocytes as a function of age. Mutat Res 1995;338:115-128.
    • (1995) Mutat Res , vol.338 , pp. 115-128
    • Barnett, Y.A.1    King, C.M.2
  • 7
    • 0032525010 scopus 로고    scopus 로고
    • DNA damage and mutation: Contributors to the age related alterations in T cell-mediated immune responses?
    • Barnett YA, Barnett CR. DNA damage and mutation: contributors to the age related alterations in T cell-mediated immune responses? Mech Ageing Dev 1998;102:165-175.
    • (1998) Mech Ageing Dev , vol.102 , pp. 165-175
    • Barnett, Y.A.1    Barnett, C.R.2
  • 8
    • 0035915785 scopus 로고    scopus 로고
    • The effects of carnosine on oxidative DNA damage levels and in vitro lifespan in human peripheral blood derived CD4- T-cell clones
    • Hyland P, Duggan O, Hipkiss A, Barnett C, Barnett Y. The effects of carnosine on oxidative DNA damage levels and in vitro lifespan in human peripheral blood derived CD4- T-cell clones. Mech Ageing Dev 2000;121:203-215.
    • (2000) Mech Ageing Dev , vol.121 , pp. 203-215
    • Hyland, P.1    Duggan, O.2    Hipkiss, A.3    Barnett, C.4    Barnett, Y.5
  • 9
    • 0030872907 scopus 로고    scopus 로고
    • Selective targeting of bioactive compounds to mitochondria
    • Murphy MP. Selective targeting of bioactive compounds to mitochondria. Trends Biotechnol 1997;15:326-330.
    • (1997) Trends Biotechnol , vol.15 , pp. 326-330
    • Murphy, M.P.1
  • 11
    • 0041419866 scopus 로고    scopus 로고
    • MitoQ counteracts telomere shortening and elongates lifespan of fibroblasts under mild oxidative stress
    • Saretzki G, Murphy MP, von Zglinicki T. MitoQ counteracts telomere shortening and elongates lifespan of fibroblasts under mild oxidative stress. Aging Cell 2003;2: 141-143.
    • (2003) Aging Cell , vol.2 , pp. 141-143
    • Saretzki, G.1    Murphy, M.P.2    Von Zglinicki, T.3
  • 12
    • 0033088957 scopus 로고    scopus 로고
    • The role of glutathione in the regulation of apoptosis
    • Hall AG. The role of glutathione in the regulation of apoptosis. Eur J Clin Invest 1999;29:238-245.
    • (1999) Eur J Clin Invest , vol.29 , pp. 238-245
    • Hall, A.G.1
  • 14
    • 0030865646 scopus 로고    scopus 로고
    • Dual regulation of caspase activity by hydrogen peroxide: Implications for apoptosis
    • Hampton MB, Orenius S. Dual regulation of caspase activity by hydrogen peroxide: implications for apoptosis. FEBS Lett 1997;414:552-556.
    • (1997) FEBS Lett , vol.414 , pp. 552-556
    • Hampton, M.B.1    Orenius, S.2
  • 15
    • 0033590630 scopus 로고    scopus 로고
    • Hydrogen peroxide induced apoptosis is CD95 independent, requires the release of mitochondria derived reactive oxygen species and the activation of NF-HB
    • Dumont A, Hehner SP, Hofmann TG, Ueffi ng M, Droge W, Schmitz ML. Hydrogen peroxide induced apoptosis is CD95 independent, requires the release of mitochondria derived reactive oxygen species and the activation of NF- ffB. Oncogene 1999;18:747-757.
    • (1999) Oncogene , vol.18 , pp. 747-757
    • Dumont, A.1    Hehner, S.P.2    Hofmann, T.G.3    Ueffing, M.4    Droge, W.5    Schmitz, M.L.6
  • 16
    • 34249730062 scopus 로고    scopus 로고
    • Identifi cation of immunogenic MHC class II tyrosinase derived peptides using HLA-DR1 and HLA-DR4 transgenic mice
    • Horton RBV, Laversin SAS, Reeder SP, Rees RC, McArdle SEB. Identifi cation of immunogenic MHC class II tyrosinase derived peptides using HLA-DR1 and HLA-DR4 transgenic mice. Prot Peptide Lett 2007;14:455-460.
    • (2007) Prot Peptide Lett , vol.14 , pp. 455-460
    • Rbv, H.1    Sas, L.2    Reeder, S.P.3    Rees, R.C.4    McArdle, S.E.B.5
  • 17
    • 0027375157 scopus 로고
    • Direct enzymatic detection of endogenous oxidative base damage in human lymphocyte DNA
    • Collins AR, Duthie SJ, Dobson VL. Direct enzymatic detection of endogenous oxidative base damage in human lymphocyte DNA. Carcinogenesis 1993;14:1733-1735.
    • (1993) Carcinogenesis , vol.14 , pp. 1733-1735
    • Collins, A.R.1    Duthie, S.J.2    Dobson, V.L.3
  • 18
    • 1642503846 scopus 로고    scopus 로고
    • Effects of a reduced oxygen culture system on human T cell clones as a function of in vitro age
    • Duggan O, Hyland P, Annett K, Freeburrn, Barnett C, Pawelec G, Barnett Y. Effects of a reduced oxygen culture system on human T cell clones as a function of in vitro age. Exp Gerontol 2004;39:525-530.
    • (2004) Exp Gerontol , vol.39 , pp. 525-530
    • Duggan, O.1    Hyland, P.2    Annett, K.3    Freeburrn Barnett, C.4    Pawelec, G.5    Barnett, Y.6
  • 20
    • 58249093939 scopus 로고    scopus 로고
    • How mitochondria produce reactive oxygen species
    • Murphy MP. How mitochondria produce reactive oxygen species. Biochem J 2009;417:1-13.
    • (2009) Biochem J , vol.417 , pp. 1-13
    • Murphy, M.P.1
  • 23
    • 0031916984 scopus 로고    scopus 로고
    • The free radical theory of ageing matures
    • Beckman KB, Ames BN. The free radical theory of ageing matures. Physiol Rev 1998;78:547-581.
    • (1998) Physiol Rev , vol.78 , pp. 547-581
    • Beckman, K.B.1    Ames, B.N.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.