Enhanced estradiol-induced vasorelaxation in aortas from type 2 diabetic mice may reflect a compensatory role of p38 MAPK-mediated eNOS activation

Pflugers Archiv European Journal of Physiology

Volumn 464, Issue 2, 2012, Pages 205-215

  Taguchi, Kumiko ^a   Morishige, Akitaka ^a   Matsumoto, Takayuki ^a   Kamata, Katsuo ^a   Kobayashi, Tsuneo ^a  

^a HOSHI UNIVERSITY   (Japan)

Author keywords

ENOS phosphorylation; Estradiol; Female; MAPK pathway; Type 2 diabetes

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; GLUCOSE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE B; PROTEIN KINASE B INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME REGULATION; ESTRADIOL BLOOD LEVEL; ESTROGEN ACTIVITY; FEMALE; GLUCOSE BLOOD LEVEL; HEART PROTECTION; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; STREPTOZOCIN DIABETES; VASODILATATION;

ANIMALS; AORTA; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; ESTRADIOL; ESTROGENS; FEMALE; MICE; NITRATES; NITRIC OXIDE SYNTHASE TYPE III; NITRITES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; VASODILATION;

EID: 84864494684     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-012-1131-x     Document Type: Article

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