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Volumn 7, Issue 12, 2010, Pages 3857-3867

p38 Mitogen-Activated Protein Kinase (MAPK) increases arginase activity and contributes to endothelial dysfunction in corpora cavernosa from angiotensin-II-treated mice

Author keywords

Angiotensin II; Arginase Activity; Erectile Dysfunction; Nitric Oxide; P38 MAPK

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACETYLCHOLINE; ANGIOTENSIN II; ARGINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE SYNTHASE; PHENYLEPHRINE; SODIUM CHLORIDE;

EID: 78649844792     PISSN: 17436095     EISSN: 17436109     Source Type: Journal    
DOI: 10.1111/j.1743-6109.2010.01996.x     Document Type: Article
Times cited : (43)

References (50)
  • 1
    • 0034849563 scopus 로고    scopus 로고
    • Pharmacology of penile erection
    • Andersson KE. Pharmacology of penile erection. Pharmacol Rev 2001;53:417-50.
    • (2001) Pharmacol Rev , vol.53 , pp. 417-450
    • Andersson, K.E.1
  • 3
    • 33750447627 scopus 로고    scopus 로고
    • Chronic administration of an oral Rho kinase inhibitor prevents the development of vasculogenic erectile dysfunction in a rat model
    • Park K, Kim SW, Rhu KS, Paick JS. Chronic administration of an oral Rho kinase inhibitor prevents the development of vasculogenic erectile dysfunction in a rat model. J Sex Med 2006;3:996-1003.
    • (2006) J Sex Med , vol.3 , pp. 996-1003
    • Park, K.1    Kim, S.W.2    Rhu, K.S.3    Paick, J.S.4
  • 5
    • 0042320832 scopus 로고    scopus 로고
    • Two phases of nitrergic neuropathy in streptozotocin-induced diabetic rats
    • Cellek S, Foxwell NA, Moncada S. Two phases of nitrergic neuropathy in streptozotocin-induced diabetic rats. Diabetes 2003;52:2353-62.
    • (2003) Diabetes , vol.52 , pp. 2353-2362
    • Cellek, S.1    Foxwell, N.A.2    Moncada, S.3
  • 8
    • 0034816774 scopus 로고    scopus 로고
    • Increased expression of arginase II in human diabetic corpus cavernosum: In diabetic-associated erectile dysfunction
    • Bivalacqua TJ, Hellstrom WJ, Kadowitz PJ, Champion HC. Increased expression of arginase II in human diabetic corpus cavernosum: In diabetic-associated erectile dysfunction. Biochem Biophys Res Commun 2001;283:923-7.
    • (2001) Biochem Biophys Res Commun , vol.283 , pp. 923-927
    • Bivalacqua, T.J.1    Hellstrom, W.J.2    Kadowitz, P.J.3    Champion, H.C.4
  • 9
    • 33847700110 scopus 로고    scopus 로고
    • Overexpression of arginase in the aged mouse penis impairs erectile function and decreases eNOS activity: Influence of in vivo gene therapy of anti-arginase
    • Bivalacqua TJ, Burnett AL, Hellstrom WJ, Champion HC. Overexpression of arginase in the aged mouse penis impairs erectile function and decreases eNOS activity: Influence of in vivo gene therapy of anti-arginase. Am J Physiol Heart Circ Physiol 2007;292:H1340-51.
    • (2007) Am J Physiol Heart Circ Physiol , vol.292
    • Bivalacqua, T.J.1    Burnett, A.L.2    Hellstrom, W.J.3    Champion, H.C.4
  • 12
    • 34447343830 scopus 로고    scopus 로고
    • Roles of attenuated neuronal nitric-oxide synthase protein expression and accelerated arginase activity in impairing neurogenic relaxation of corpus cavernosum in aged rabbits
    • Numao N, Masuda H, Sakai Y, Okada Y, Kihara K, Azuma H. Roles of attenuated neuronal nitric-oxide synthase protein expression and accelerated arginase activity in impairing neurogenic relaxation of corpus cavernosum in aged rabbits. BJU Int 2007;99:1495-9.
    • (2007) BJU Int , vol.99 , pp. 1495-1499
    • Numao, N.1    Masuda, H.2    Sakai, Y.3    Okada, Y.4    Kihara, K.5    Azuma, H.6
  • 13
    • 0034618752 scopus 로고    scopus 로고
    • Regulation of nitric oxide production by arginine metabolic enzymes
    • Mori M, Gotoh T. Regulation of nitric oxide production by arginine metabolic enzymes. Biochem Biophys Res Commun 2000;275:715-9.
    • (2000) Biochem Biophys Res Commun , vol.275 , pp. 715-719
    • Mori, M.1    Gotoh, T.2
  • 15
    • 0036402941 scopus 로고    scopus 로고
    • Regulation of enzymes of the urea cycle and arginine metabolism
    • Morris SM Jr. Regulation of enzymes of the urea cycle and arginine metabolism. Annu Rev Nutr 2002;22:87-105.
    • (2002) Annu Rev Nutr , vol.22 , pp. 87-105
    • Morris Jr, S.M.1
  • 17
    • 0032708345 scopus 로고    scopus 로고
    • Arginase-boronic acid complex highlights a physiological role in erectile function
    • Cox JD, Kim NN, Traish AM, Christianson DW. Arginase-boronic acid complex highlights a physiological role in erectile function. Nat Struct Biol 1999;6:1043-7.
    • (1999) Nat Struct Biol , vol.6 , pp. 1043-1047
    • Cox, J.D.1    Kim, N.N.2    Traish, A.M.3    Christianson, D.W.4
  • 18
    • 0036762815 scopus 로고    scopus 로고
    • Recent advances in angiotensin II signaling
    • Touyz RM, Berry C. Recent advances in angiotensin II signaling. Braz J Med Biol Res 2002;35:1001-15.
    • (2002) Braz J Med Biol Res , vol.35 , pp. 1001-1015
    • Touyz, R.M.1    Berry, C.2
  • 19
    • 0030893387 scopus 로고    scopus 로고
    • Tissue angiotensin II as a modulator of erectile function. I. Angiotensin peptide content, secretion and effects in the corpus cavernosum
    • Kifor I, Williams GH, Vickers MA, Sullivan MP, Jodbert P, Dluhy RG. Tissue angiotensin II as a modulator of erectile function. I. Angiotensin peptide content, secretion and effects in the corpus cavernosum. J Urol 1997;157:1920-5.
    • (1997) J Urol , vol.157 , pp. 1920-1925
    • Kifor, I.1    Williams, G.H.2    Vickers, M.A.3    Sullivan, M.P.4    Jodbert, P.5    Dluhy, R.G.6
  • 21
    • 10544246489 scopus 로고    scopus 로고
    • Reactive oxygen species produced by macrophage-derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro. Implications for atherosclerotic plaque stability
    • Rajagopalan S, Meng XP, Ramasamy S, Harrison DG, Galis ZS. Reactive oxygen species produced by macrophage-derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro. Implications for atherosclerotic plaque stability. J Clin Invest 1996;98:2572-9.
    • (1996) J Clin Invest , vol.98 , pp. 2572-2579
    • Rajagopalan, S.1    Meng, X.P.2    Ramasamy, S.3    Harrison, D.G.4    Galis, Z.S.5
  • 22
    • 40349113071 scopus 로고    scopus 로고
    • NADPH oxidase activation: A mechanism of hypertension-associated erectile dysfunction
    • Jin L, Lagoda G, Leite R, Webb RC, Burnett AL. NADPH oxidase activation: A mechanism of hypertension-associated erectile dysfunction. J Sex Med 2008;5:544-51.
    • (2008) J Sex Med , vol.5 , pp. 544-551
    • Jin, L.1    Lagoda, G.2    Leite, R.3    Webb, R.C.4    Burnett, A.L.5
  • 23
    • 0036591592 scopus 로고    scopus 로고
    • Inhibition of mitogen-activated protein/extracellular signal-regulated kinase improves endothelial function and attenuates AngII-induced contractility of mesenteric resistance arteries from spontaneously hypertensive rats
    • Touyz RM, Deschepper C, Park JB, He G, Chen X, Neves MF, Virdis A, Schiffrin EL. Inhibition of mitogen-activated protein/extracellular signal-regulated kinase improves endothelial function and attenuates AngII-induced contractility of mesenteric resistance arteries from spontaneously hypertensive rats. J Hypertens 2002;20:1127-34.
    • (2002) J Hypertens , vol.20 , pp. 1127-1134
    • Touyz, R.M.1    Deschepper, C.2    Park, J.B.3    He, G.4    Chen, X.5    Neves, M.F.6    Virdis, A.7    Schiffrin, E.L.8
  • 24
    • 33644857156 scopus 로고    scopus 로고
    • Angiotensin II regulates vascular and endothelial dysfunction: Recent topics of angiotensin II type-1 receptor signaling in the vasculature
    • Nakashima H, Suzuki H, Ohtsu H, Chao JY, Utsunomiya H, Frank GD, Eguchi S. Angiotensin II regulates vascular and endothelial dysfunction: Recent topics of angiotensin II type-1 receptor signaling in the vasculature. Curr Vasc Pharmacol 2006;4:67-78.
    • (2006) Curr Vasc Pharmacol , vol.4 , pp. 67-78
    • Nakashima, H.1    Suzuki, H.2    Ohtsu, H.3    Chao, J.Y.4    Utsunomiya, H.5    Frank, G.D.6    Eguchi, S.7
  • 25
    • 0035195970 scopus 로고    scopus 로고
    • Vascular factors and metabolic interactions in the pathogenesis of diabetic neuropathy
    • Cameron NE, Eaton SE, Cotter MA, Tesfaye S. Vascular factors and metabolic interactions in the pathogenesis of diabetic neuropathy. Diabetologia 2001;44:1973-88.
    • (2001) Diabetologia , vol.44 , pp. 1973-1988
    • Cameron, N.E.1    Eaton, S.E.2    Cotter, M.A.3    Tesfaye, S.4
  • 27
    • 0038300382 scopus 로고    scopus 로고
    • Endothelial activation by angiotensin II through NFkappaB and p38 pathways: Involvement of NFkappaB-inducible kinase (NIK), free oxygen radicals, and selective inhibition by aspirin
    • Costanzo A, Moretti F, Burgio VL, Bravi C, Guido F, Levrero M, Puri PL. Endothelial activation by angiotensin II through NFkappaB and p38 pathways: Involvement of NFkappaB-inducible kinase (NIK), free oxygen radicals, and selective inhibition by aspirin. J Cell Physiol 2003;195:402-10.
    • (2003) J Cell Physiol , vol.195 , pp. 402-410
    • Costanzo, A.1    Moretti, F.2    Burgio, V.L.3    Bravi, C.4    Guido, F.5    Levrero, M.6    Puri, P.L.7
  • 28
    • 33646544053 scopus 로고    scopus 로고
    • Correction of nitrergic neurovascular dysfunction in diabetic mouse corpus cavernosum by p38 mitogen-activated protein kinase inhibition
    • Nangle MR, Cotter MA, Cameron NE. Correction of nitrergic neurovascular dysfunction in diabetic mouse corpus cavernosum by p38 mitogen-activated protein kinase inhibition. Int J Impot Res 2006;18:258-63.
    • (2006) Int J Impot Res , vol.18 , pp. 258-263
    • Nangle, M.R.1    Cotter, M.A.2    Cameron, N.E.3
  • 29
    • 0032563677 scopus 로고    scopus 로고
    • "Stress-responsive" mitogen-activated protein kinases (c-Jun N-terminal kinases and p38 mitogen-activated protein kinases) in the myocardium
    • Sugden PH, Clerk A. "Stress-responsive" mitogen-activated protein kinases (c-Jun N-terminal kinases and p38 mitogen-activated protein kinases) in the myocardium. Circ Res 1998;83:345-52.
    • (1998) Circ Res , vol.83 , pp. 345-352
    • Sugden, P.H.1    Clerk, A.2
  • 30
    • 0034090421 scopus 로고    scopus 로고
    • Differential activation of mitogen-activated protein kinases in smooth muscle cells by angiotensin II: Involvement of p22phox and reactive oxygen species
    • Viedt C, Soto U, Krieger-Brauer HI, Fei J, Elsing C, Kübler W, Kreuzer J. Differential activation of mitogen-activated protein kinases in smooth muscle cells by angiotensin II: Involvement of p22phox and reactive oxygen species. Arterioscler Thromb Vasc Biol 2000;20:940-8.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 940-948
    • Viedt, C.1    Soto, U.2    Krieger-Brauer, H.I.3    Fei, J.4    Elsing, C.5    Kübler, W.6    Kreuzer, J.7
  • 32
    • 0346788518 scopus 로고    scopus 로고
    • ROS during the acute phase of Ang II hypertension participates in cardiovascular MAPK activation but not vasoconstriction
    • Zhang GX, Kimura S, Nishiyama A, Shokoji T, Rahman M, Abe Y. ROS during the acute phase of Ang II hypertension participates in cardiovascular MAPK activation but not vasoconstriction. Hypertension 2004;43:117-24.
    • (2004) Hypertension , vol.43 , pp. 117-124
    • Zhang, G.X.1    Kimura, S.2    Nishiyama, A.3    Shokoji, T.4    Rahman, M.5    Abe, Y.6
  • 36
    • 1642554787 scopus 로고    scopus 로고
    • Arginase induction promotes Trypanosoma cruzi intracellular replication in Cruzipain-treated J774 cells through the activation of multiple signaling pathways
    • Stempin CC, Tanos TB, Coso OA, Cerbán FM. Arginase induction promotes Trypanosoma cruzi intracellular replication in Cruzipain-treated J774 cells through the activation of multiple signaling pathways. Eur J Immunol 2004;34:200-9.
    • (2004) Eur J Immunol , vol.34 , pp. 200-209
    • Stempin, C.C.1    Tanos, T.B.2    Coso, O.A.3    Cerbán, F.M.4
  • 38
    • 78649826077 scopus 로고    scopus 로고
    • Angiotensin II elevates endothelial arginase activity via RhoA/MAPK pathways
    • (Abstract).
    • Shatanawi A, Romero MJ, Iddings JA, Caldwell RB, Caldwell RW. Angiotensin II elevates endothelial arginase activity via RhoA/MAPK pathways. Faseb J 2010;24:959.2 (Abstract).
    • (2010) Faseb J , vol.24 , pp. 9592
    • Shatanawi, A.1    Romero, M.J.2    Iddings, J.A.3    Caldwell, R.B.4    Caldwell, R.W.5
  • 39
    • 36049042645 scopus 로고    scopus 로고
    • Effects of p38 mitogen-activated protein kinase inhibition on blood pressure, renal hemodynamics, and renal vascular reactivity in normal and diabetic rats
    • Komers R, Schutzer W, Xue H, Oyama TT, Lindsley JN, Anderson S. Effects of p38 mitogen-activated protein kinase inhibition on blood pressure, renal hemodynamics, and renal vascular reactivity in normal and diabetic rats. Transl Res 2007;150:343-9.
    • (2007) Transl Res , vol.150 , pp. 343-349
    • Komers, R.1    Schutzer, W.2    Xue, H.3    Oyama, T.T.4    Lindsley, J.N.5    Anderson, S.6
  • 40
    • 0032510977 scopus 로고    scopus 로고
    • p38 mitogen-activated protein kinase is a critical component of the redox-sensitive signaling pathways activated by angiotensin II. Role in vascular smooth muscle cell hypertrophy
    • Ushio-Fukai M, Alexander RW, Akers M, Griendling KK. p38 mitogen-activated protein kinase is a critical component of the redox-sensitive signaling pathways activated by angiotensin II. Role in vascular smooth muscle cell hypertrophy. J Biol Chem 1998;273:15022-9.
    • (1998) J Biol Chem , vol.273 , pp. 15022-15029
    • Ushio-Fukai, M.1    Alexander, R.W.2    Akers, M.3    Griendling, K.K.4
  • 41
    • 2442421008 scopus 로고    scopus 로고
    • Angiotensin II differentially regulates interleukin-1-beta-inducible NO synthase (iNOS) and vascular cell adhesion molecule-1 (VCAM-1) expression: Role of p38 MAPK
    • Jiang B, Xu S, Hou X, Pimentel DR, Cohen RA. Angiotensin II differentially regulates interleukin-1-beta-inducible NO synthase (iNOS) and vascular cell adhesion molecule-1 (VCAM-1) expression: Role of p38 MAPK. J Biol Chem 2004;279:20363-8.
    • (2004) J Biol Chem , vol.279 , pp. 20363-20368
    • Jiang, B.1    Xu, S.2    Hou, X.3    Pimentel, D.R.4    Cohen, R.A.5
  • 42
    • 33745066911 scopus 로고    scopus 로고
    • Angiotensin-(1-7) inhibits angiotensin II-stimulated phosphorylation of MAP kinases in proximal tubular cells
    • Su Z, Zimpelmann J, Burns KD. Angiotensin-(1-7) inhibits angiotensin II-stimulated phosphorylation of MAP kinases in proximal tubular cells. Kidney Int 2006;69:2212-8.
    • (2006) Kidney Int , vol.69 , pp. 2212-2218
    • Su, Z.1    Zimpelmann, J.2    Burns, K.D.3
  • 44
    • 0037083375 scopus 로고    scopus 로고
    • MAPKK-independent activation of p38 alpha mediated by TAB1-dependent autophosphorylation of p38 alpha
    • Ge B, Gram H, Di Padova F, Huang B, New L, Ulevitch RJ, Luo Y, Han J. MAPKK-independent activation of p38 alpha mediated by TAB1-dependent autophosphorylation of p38 alpha. Science 2002;295:1291-4.
    • (2002) Science , vol.295 , pp. 1291-1294
    • Ge, B.1    Gram, H.2    Di Padova, F.3    Huang, B.4    New, L.5    Ulevitch, R.J.6    Luo, Y.7    Han, J.8
  • 45
    • 32244435178 scopus 로고    scopus 로고
    • eNOS function and dysfunction in the penis
    • Musicki B, Burnett AL. eNOS function and dysfunction in the penis. Exp Biol Med (Maywood) 2006;231:154-65.
    • (2006) Exp Biol Med (Maywood) , vol.231 , pp. 154-165
    • Musicki, B.1    Burnett, A.L.2
  • 47
    • 39149109282 scopus 로고    scopus 로고
    • Low intensity pulsed ultrasound accelerates macrophage phagocytosis by a pathway that requires actin polymerization, Rho, and Src/MAPKs activity
    • Zhou S, Bachem MG, Seufferlein T, Li Y, Gross HJ, Schmelz A. Low intensity pulsed ultrasound accelerates macrophage phagocytosis by a pathway that requires actin polymerization, Rho, and Src/MAPKs activity. Cell Signal 2008;20:695-704.
    • (2008) Cell Signal , vol.20 , pp. 695-704
    • Zhou, S.1    Bachem, M.G.2    Seufferlein, T.3    Li, Y.4    Gross, H.J.5    Schmelz, A.6
  • 48
    • 78649894619 scopus 로고    scopus 로고
    • Peroxynitrite and hydrogen peroxide increase arginase activity through the RhoA/Rho kinase (RAK) pathway
    • (Abstract).
    • Chandra S, Romero MJ, Shatanawi A, Caldwell RB, Caldwell RW. Peroxynitrite and hydrogen peroxide increase arginase activity through the RhoA/Rho kinase (RAK) pathway. Faseb J 2010;24:959.4 (Abstract).
    • (2010) Faseb J , vol.24 , pp. 9594
    • Chandra, S.1    Romero, M.J.2    Shatanawi, A.3    Caldwell, R.B.4    Caldwell, R.W.5
  • 49
    • 0442309045 scopus 로고    scopus 로고
    • Augmented contractile response of vascular smooth muscle in a diabetic mouse model
    • Okon EB, Szado T, Laher I, McManus B, Van Breemen C. Augmented contractile response of vascular smooth muscle in a diabetic mouse model. J Vasc Res 2003;40:520-30.
    • (2003) J Vasc Res , vol.40 , pp. 520-530
    • Okon, E.B.1    Szado, T.2    Laher, I.3    McManus, B.4    Van Breemen, C.5
  • 50
    • 61849097698 scopus 로고    scopus 로고
    • Angiotensin II signaling and its implication in erectile dysfunction
    • Jin LM. Angiotensin II signaling and its implication in erectile dysfunction. J Sex Med 2009;3:302-10.
    • (2009) J Sex Med , vol.3 , pp. 302-310
    • Jin, L.M.1


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