Molecular hydrogen reduces lps-induced neuroinflammation and promotes recovery from sickness behaviour in mice

PLoS ONE

Volumn 7, Issue 7, 2012, Pages

  Spulber, Stefan ^a   Edoff, Karin ^a   Hong, Lie ^a   Morisawa, Shinkatsu ^b   Shirahata, Sanetaka ^c   Ceccatelli, Sandra ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b Nihon Trim Co Ltd   (Japan)

^c KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; DRINKING WATER; ELECTROCHEMICALLY REDUCED WATER; HEME OXYGENASE 1; HYDROGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MOLECULAR HYDROGEN; TRANSCRIPTION FACTOR NRF2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

AMPLITUDE MODULATION; ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL ACTIVATION; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; CONVALESCENCE; DISEASE DURATION; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; GENE ACTIVATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HIPPOCAMPUS; ILLNESS BEHAVIOR; IN VIVO STUDY; LOCOMOTION; MALE; MICROGLIA; MOUSE; NERVOUS SYSTEM INFLAMMATION; NEUROMODULATION; NEUROPROTECTION; NONHUMAN; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION;

ANIMALS; BEHAVIOR, ANIMAL; CENTRAL NERVOUS SYSTEM DISEASES; CULTURE MEDIA; CYTOKINES; HYDROGEN; INFLAMMATION; LIPOPOLYSACCHARIDES; LOCOMOTION; MALE; MICE; MICE, INBRED C57BL;

MURINAE; MUS;

EID: 84864475936     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0042078     Document Type: Article

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