Molecular hydrogen suppresses FcεRI-mediated signal transduction and prevents degranulation of mast cells

Biochemical and Biophysical Research Communications

Volumn 389, Issue 4, 2009, Pages 651-656

  Itoh, Tomohiro ^a   Fujita, Yasunori ^a   Ito, Mikako ^b   Masuda, Akio ^b   Ohno, Kinji ^b   Ichihara, Masatoshi ^c   Kojima, Toshio ^d   Nozawa, Yoshinori ^a,e   Ito, Masafumi ^a  

^a GIFU INTERNATIONAL INSTITUTE OF BIOTECHNOLOGY   (Japan)

^b NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c CHUBU UNIVERSITY   (Japan)

^d RIKEN   (Japan)

^e TOKAI GAKUEN UNIVERSITY   (Japan)

Author keywords

Fc RI; Immediate type allergic reaction; Mast cell; Molecular hydrogen; Signal transduction

Indexed keywords

FC EPSILON RECEPTOR I; FC RECEPTOR; HYDROGEN; HYDROGEN PEROXIDE; HYDROXYL RADICAL; NITRIC OXIDE; PROTEIN KINASE LYN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; UNCLASSIFIED DRUG;

ALLERGIC REACTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DEGRANULATION; ENZYME ACTIVITY; FLUID INTAKE; IMMEDIATE TYPE HYPERSENSITIVITY; MALE; MAST CELL; NONHUMAN; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; CELL DEGRANULATION; CELL LINE, TUMOR; HYDROGEN; MAST CELLS; MICE; MICE, INBRED ICR; NADPH OXIDASE; PHOSPHORYLATION; RATS; RECEPTORS, IGE; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES;

ANIMALIA; MUS; RATTUS;

EID: 70349748784     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.09.047     Document Type: Article

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