Behavioral effects of cytokines

Brain, Behavior, and Immunity

Volumn 15, Issue 4, 2001, Pages 371-387

  Larson, Susan J ^a   Dunn, Adrian J ^b  

^a Université du Québec à Montréal   (United States)

^b LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR;

ADAPTIVE BEHAVIOR; ANHEDONIA; ANIMAL BEHAVIOR; BEHAVIOR; COGNITION; COGNITIVE DEFECT; CYTOKINE PRODUCTION; DEPRESSION; EXPLORATORY BEHAVIOR; FOOD INTAKE; ILLNESS BEHAVIOR; IMMUNE SYSTEM; INFECTION; INFLAMMATION; INGESTION; LEARNING; NEUROPSYCHIATRY; PRIORITY JOURNAL; REVIEW; SEXUAL BEHAVIOR; SLEEP; SOCIAL BEHAVIOR;

EID: 0035674756     PISSN: 08891591     EISSN: None     Source Type: Journal    
DOI: 10.1006/brbi.2001.0643     Document Type: Article

References (90)

1. Differential effects of interleukin (IL)-1β, IL-2 and IL-6 on responding for rewarding lateral hypothalamic stimulation
2. Interleukin-2 decreases accumbal dopamine efflux and responding for rewarding lateral hypothalamic stimulation
3. Anhedonic and anxiogenic effects of cytokine exposure
4. Naloxone alters locomotion and interaction with environmental stimuli
5. Sickness and behaviour in animals: A motivational perspective
6. Differential effects of lipopolysaccharide on pup retrieving and nest building in lactating mice
7. Differential effects of lipopolysaccharide on food hoarding behavior and food consumption in rats
8. Pyrogens specifically disrupt the acquisition of a task involving cognitive processing in the rat
9. Effects of interleukin-1 on sexual attractivity in a model of sickness behavior
10. Gender differences in the behavioral response to interleukin-1: Neurochemical mechanisms
11. Administration of interleukin-1 into the hypothalamic paraventricular nucleus febrile and behavioral effects
12. Passage of cytokines across the blood-brain barrier
13. Interleukin 1β inhibits synaptic strength and long-term potentiation in the rat CA1 hippocampus
14. Tumor growth in rats: Conditioned suppression of food intake and preference
15. Interleukin-1 mediates behavioural but not metabolic effects of tumor necrosis factor α in mice
16. Effects of interleukin-1 receptor antagonist on the behavioral effects of lipopolysaccharide in rat
17. Central mediation of the effects of interleukin-1 on social exploration and body weight in mice
18. Interleukin-6 is active only in presence of other proinflammatory cytokines to induce sickness behavior
19. Role of IL-1 in cytokine-induced sickness behavior: A study with IL-6 deficient mice
20. Synergy between tumor necrosis factor α and interleukin-1 in the induction of sickness behavior in mice
21. Lipopolysaccharide, central in vivo amine variations, and anhedonia
22. Lipopolysaccharide and interleukin-1 depress food-motivated behavior in mice by a vagal-mediated mechanism
23. Endothelial cells of the rat brain vasculature express cyclooxygenase-2 mRNA in response to systemic interleukin-1β: A possible site of prostaglandin synthesis responsible for fever
24. Involvement of cyclooxygenase-2 in LPS-induced fever and regulation of its mRNA by LPS in the rat brain
25. Chronic treatment with the atypical antidepressant tianeptine attenuates sickness behavior induced by peripheral but not central lipopolysaccharide and interleukin-1β in the rat
26. Aphagic and adipsic effects of interleukin-1
27. The malaise theory of depression: Major depressive disorder is sickness behavior and antidepressants are analgesic
28. Behavioral effects of peripherally injected interleukin-1: Role of prostaglandins
29. Cytokine-induced sickness behavior: Where do we stand?
30. Cytokine actions on behavior
31. Cytokines, stress and depression
32. Effects of cytokines and infections on brain neurochemistry
33. Endotoxin-induced behavioral changes of mice in the multicompartment chamber are distinct from those of interleukin-1
34. Reduction of exploratory behavior by intraperitoneal injection of interleukin-1 involves brain corticotropin-releasing factor
35. The role of cyclooxygenases in endotoxin- and interleukin-1-induced hypophagia
36. The reduction in sweetened milk intake induced by interleukin-1 and endotoxin is not prevented by chronic antidepressant treatment
37. IL-1 beta impairs relational but not procedural rodent: Learning in a water maze task
38. Spatial learning impairment in mice infected with Legionella pneumophila or administered exogenous interleukin-1-β
39. Corticosterone regulates behavioral effects of lipopolysaccharide and interleukin-1β in mice
40. Biological basis of the behavior of sick animals
41. Endotoxin-induced changes in sleep and sleepiness during the day
42. Tumor necrosis factor-beta induces sleep, fever, and anorexia
43. Interleukin 1ββ inhibits long-term potentiation in the CA3 region of mouse hippocampal slices
44. Involvement of organum vasculosum of lamina terminalis and preoptic area in interleukin 1β-induced ACTH release
45. Sickness behavior as a new target for drug development
46. Reduction in food and water intake induced by microinjection of interleukin-1β in the ventromedial hypothalamus of the rat
47. Somnogenic effects of rabbit and recombinant human interferons in rabbits
48. Microbial products and cytokines in sleep and fever regulation
49. Cytokines as regulators of sleep
50. Dissociation of temperature changes and anorexia after experimental colitis and LPS administration in rats
51. Effects of interleukin-1 on food-maintained behavior in the mouse
52. Central administration of rat interleu-kin-6 induces hypothalamus-pituitary-adrenal activation and fever but not sickness behavior in rats
53. Activation of serotonergic and noradrenergic neurotransmission in the rat hippocampus after peripheral administration of bacterial endotoxin: Involvement of the cyclo-oxygenase pathway
54. The role of fever in appetite suppression after endotoxin administration
55. Suppression of food intake during infections: Is interleukin-1 involved?
56. Effect of centrally administered interleukin-1 and endotoxin on food intake of fasted rats
57. On the suppression of food intake in experimental models of colitis in the rat
58. Some psychophysiological studies of motivation and of the behavioral effects of illness
59. Dose-dependent effects of endotoxin on human sleep
60. Interleukin-1β, but not interleukin-6, impairs spatial navigation learning
61. Correlation between food intake and CSF IL-1α in anorectic tumor bearing rats
62. Interleukin-1 involvement in the regulation of sleep
63. Interleukin-1 alters rat sleep: Temporal and dose-related effects
64. Pattern of neurobehavioral deficits associated with interferon-α therapy for leukemia
65. Corticosterone controls interleukin-1β expression and sickness behavior in the rat
66. Meal patterns in response to the intracerebroventricular administration of interleukin-1β in rats
67. Anorexia during acute and chronic disease
68. Central nervous system mechanisms contributing to the cachexia-anorexia syndrome
69. Tumor necrosis factor and interleukin-1β: Suppression of food intake by direct action in the central nervous system
70. The immune system and memory consolidation: A role for cytokine IL-1β
71. Human immunodeficiency virus-1 coat protein gp120 impairs contextual fear learning: A potential role in AIDS related learning and memory impairments
72. Selective effects of peripheral lipopolysaccharide administration on contextual and auditory-cue fear conditioning
73. Role of interleukin-1 beta in impairment of contextual fear conditioning caused by social isolation
74. Cytokine-associated emotional and cognitive disturbances in humans
75. Differential effect of chronic antidepressant treatments on lipopolysaccharide-induced depressive-like behavioural symptoms in the rat
76. Intracerebroventricular administration of interleukin-1 to mice alters investigation of stimuli in a novel environment
77. Progressive-ratio schedules of drug delivery in the analysis of drug self-administration: A review
78. Endotoxin- and interleukin-1-induced hypophagia are not affected by noradrenergic, dopaminergic, histaminergic and muscarinic antagonists
79. The roles of IL-1, IL-6 and TNFα in the feeding responses to endotoxin and influenza virus infection in mice
80. Cyclooxygenase 1 is not essential for hypophagic responses to interleukin-1 and endotoxin in mice
81. influenza virus infection of mice induces anorexia: Comparison with endotoxin and interleukin-1 and the effects of indomethacin
82. The role of cytokines in the behavioral responses to endotoxin and influenza virus infection in mice: Effects of acute and chronic administration of the interleukin-1-receptor antagonist (IL-1ra)
83. Anorexia induced by interleukin-1: Involvement of corticotropin-releasing factor
84. Synergism between IL-1β and TNF-α on the activity of the pituitary-adrenal axis and on food intake of rats
85. Synergistic effect of rhTNF-αand rhIL-1α in inducing anorexia in rats
86. Endotoxin produces a depressive-like episode in rats
87. Behavioral and psychological effects of immune activation: Implications for 'depression due to a general medical condition.'
88. Interleukin-1 inhibits sexual behavior in female but not in male rats
89. Differential effects of immunologic challenge on self-stimulation from the nucleus accumbens and the substantia nigra
90. Interleukin-2 and -6 induce behavioral-activating effects in mice