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Volumn 11, Issue , 2012, Pages

The detection of pfcrt and pfmdr1 point mutations as molecular markers of chloroquine drug resistance, Pahang, Malaysia

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; ASPARTIC ACID; CHLOROQUINE; ISOLEUCINE; LYSINE; MEMBRANE PROTEIN; MOLECULAR MARKER; PFCRT PROTEIN; PFMDR1 PROTEIN; SERINE; THREONINE; UNCLASSIFIED DRUG;

EID: 84864398724     PISSN: None     EISSN: 14752875     Source Type: Journal    
DOI: 10.1186/1475-2875-11-251     Document Type: Article
Times cited : (29)

References (47)
  • 1
    • 79952193925 scopus 로고    scopus 로고
    • WHO Geneva: World Health Organization
    • WHO, World Malaria Report 2010 Geneva: World Health Organization 2010
    • (2010) World Malaria Report 2010
  • 3
    • 0013842098 scopus 로고
    • Chloroquine resistant falciparum malaria in Thailand
    • Chloroquine resistant falciparum malaria in Thailand. Harinasuta T, Suntharasamai P, Viravan C, Lancet 1965 ii 657 660
    • (1965) Lancet , vol.2 , pp. 657-660
    • Harinasuta, T.1    Suntharasamai, P.2    Viravan, C.3
  • 5
    • 73049131045 scopus 로고
    • Observations on two Plasmodium falciparum infections with an abnormal response to chloroquine
    • 13772281
    • Observations on two Plasmodium falciparum infections with an abnormal response to chloroquine. Moore DV, Lanier JE, Am J Trop Med Hyg 1961 10 5 9 13772281
    • (1961) Am J Trop Med Hyg , vol.10 , pp. 5-9
    • Moore, D.V.1    Lanier, J.E.2
  • 7
    • 0021707763 scopus 로고
    • The problem of Plasmodium falciparum drug resistance in Africa south of the Sahara
    • The problem of Plasmodium falciparum drug resistance in Africa south of the Sahara. Onori E, Bull World Health Organ 1984 62 Suppl 55 62 6397277 (Pubitemid 15165246)
    • (1984) Bulletin of the World Health Organization , vol.62 , Issue.SUPPL. , pp. 55-62
    • Onori, E.1
  • 15
    • 0142155267 scopus 로고    scopus 로고
    • Application of a multi-faceted approach for the assessment of treatment response in falciparum malaria: A study from Malaysian Borneo
    • DOI 10.1016/S0020-7519(03)00199-1
    • Application of a multi-faceted approach for the assessment of treatment response in falciparum malaria: A study from Malaysian Borneo. Cox-Singh J, Lu HY, Davis TME, Ilett KF, Hackett LP, Matusop A, Singh B, Int J Parasitol 2003 33 1545 1552 10.1016/S0020-7519(03)00199-1 14572517 (Pubitemid 37324192)
    • (2003) International Journal for Parasitology , vol.33 , Issue.13 , pp. 1545-1552
    • Cox-Singh, J.1    Lu, H.Y.2    Davis, T.M.E.3    Ilett, K.F.4    Hackett, L.P.5    Matusop, A.6    Singh, B.7
  • 19
    • 79957475439 scopus 로고    scopus 로고
    • High frequency of Plasmodium falciparum chloroquine resistance marker (pfcrt T76 mutation) in Yemen: An urgent need to re-examine malaria drug policy
    • 10.1186/1756-3305-4-94 21619624
    • High frequency of Plasmodium falciparum chloroquine resistance marker (pfcrt T76 mutation) in Yemen: an urgent need to re-examine malaria drug policy. Al-Mekhlafi AM, Mahdy MA, Al-Mekhlafi HM, Azazy AA, Fong MY, Parasit Vectors 2011 4 94 10.1186/1756-3305-4-94 21619624
    • (2011) Parasit Vectors , vol.4 , pp. 94
    • Al-Mekhlafi, A.M.1    Mahdy, M.A.2    Al-Mekhlafi, H.M.3    Azazy, A.A.4    Fong, M.Y.5
  • 20
    • 3242704083 scopus 로고    scopus 로고
    • Molecular characterisation of drug-resistant Plasmodium falciparum from Thailand
    • 10.1186/1475-2875-1-12 12423551
    • Molecular characterisation of drug-resistant Plasmodium falciparum from Thailand. Lopes D, Rungsihirunrat K, Nogueira F, Seugorn A, Gil JP, do Rosario VE, Cravo P, Malar J 2002 1 12 10.1186/1475-2875-1-12 12423551
    • (2002) Malar J , vol.1 , pp. 12
    • Lopes, D.1    Rungsihirunrat, K.2    Nogueira, F.3    Seugorn, A.4    Gil, J.P.5    Do Rosario, V.E.6    Cravo, P.7
  • 21
    • 56949096093 scopus 로고    scopus 로고
    • Association between chloroquine resistance phenotypes and point mutations in pfcrt and pfmdr1 in Plasmodium falciparum isolates from Thailand
    • 10.1016/j.actatropica.2008.09.011 18950599
    • Association between chloroquine resistance phenotypes and point mutations in pfcrt and pfmdr1 in Plasmodium falciparum isolates from Thailand. Rungsihirunrat K, Chaijareonkul W, Seugorn A, Na-Bangchang K, Thaithong S, Acta Trop 2009 109 37 40 10.1016/j.actatropica.2008.09.011 18950599
    • (2009) Acta Trop , vol.109 , pp. 37-40
    • Rungsihirunrat, K.1    Chaijareonkul, W.2    Seugorn, A.3    Na-Bangchang, K.4    Thaithong, S.5
  • 22
    • 0034808372 scopus 로고    scopus 로고
    • The T76 mutation in the pfcrt gene of Plasmodium falciparum and clinical chloroquine resistance phenotypes in Papua, Indonesia
    • DOI 10.1080/00034980120092516
    • The T76 mutation in the pfcrt gene of Plasmodium falciparum and clinical chloroquine resistance phenotypes in Papua, Indonesia. Maguire JD, Susanti AI, Krisin Sismadi P, Fryauff DJ, Baird JK, Ann Trop Med Parasitol 2001 95 559 572 10.1080/00034980120092516 11672462 (Pubitemid 32928077)
    • (2001) Annals of Tropical Medicine and Parasitology , vol.95 , Issue.6 , pp. 559-572
    • Maguire, J.D.1    Susanti Krisin, A.I.2
  • 23
    • 64849116595 scopus 로고    scopus 로고
    • Association of molecular markers in Plasmodium falciparum crt and mdr1 with in vitro chloroquine resistance: A Philippine study
    • 10.1016/j.parint.2009.01.010 19567229
    • Association of molecular markers in Plasmodium falciparum crt and mdr1 with in vitro chloroquine resistance: A Philippine study. Hatabu T, Iwagami M, Kawazu S, Taguchi N, Escueta AD, Villacorte EA, Rivera PT, Kano S, Parasitol Int 2009 58 166 170 10.1016/j.parint.2009.01.010 19567229
    • (2009) Parasitol Int , vol.58 , pp. 166-170
    • Hatabu, T.1    Iwagami, M.2    Kawazu, S.3    Taguchi, N.4    Escueta, A.D.5    Villacorte, E.A.6    Rivera, P.T.7    Kano, S.8
  • 25
    • 0035341936 scopus 로고    scopus 로고
    • Polymorphisms in the Plasmodium falciparum pfcrt and pfmdr-1 genes and clinical response to chloroquine in Kampala, Uganda
    • DOI 10.1086/319865
    • Polymorphisms in the Plasmodium falciparum pfcrt and pfmdr-1 genes and clinical response to chloroquine in Kampala, Uganda. Dorsey G, Kamya MR, Singh A, Rosenthal PJ, J Infect Dis 2001 183 1417 1420 10.1086/319865 11294677 (Pubitemid 32337128)
    • (2001) Journal of Infectious Diseases , vol.183 , Issue.9 , pp. 1417-1420
    • Dorsey, G.1    Kamya, M.R.2    Singh, A.3    Rosenthal, P.J.4
  • 26
    • 0035873715 scopus 로고    scopus 로고
    • High-level chloroquine resistance in Sudanese isolates of Plasmodium falciparum is associated with mutations in the chloroquine resistance transporter gene pfcrt and the multidrug resistance gene pfmdr1
    • DOI 10.1086/320195
    • High-level chloroquine resistance in Sudanese isolates of Plasmodium falciparum is associated with mutations in the chloroquine resistance transporter gene pfcrt and the multidrug resistance gene pfmdr1. Babiker HA, Pringle SJ, Abdel-Muhsin A, Mackinnon M, Hunt P, Walliker D, J Infect Dis 2001 183 1535 1538 10.1086/320195 11319692 (Pubitemid 32417707)
    • (2001) Journal of Infectious Diseases , vol.183 , Issue.10 , pp. 1535-1538
    • Babiker, H.A.1    Pringle, S.J.2    Abdel-Muhsin, A.3    Mackinnon, M.4    Hunt, P.5    Walliker, D.6
  • 28
    • 2942622405 scopus 로고    scopus 로고
    • Variations in the sequence and expression of the Plasmodium falciparum chloroquine resistance transporter (Pfcrt) and their relationship to chloroquine resistance in vitro
    • DOI 10.1016/j.molbiopara.2004.03.016, PII S0166685104001355
    • Variations in the sequence and expression of the Plasmodium falciparum chloroquine resistance transporter (pfcrt) and their relationship to chloroquine resistance in vitro. Durrand V, Berry A, Sem R, Glaziou P, Beaudou J, Fandeur T, Mol Biochem Parasitol 2004 136 273 285 10.1016/j.molbiopara.2004.03.016 15478806 (Pubitemid 38757996)
    • (2004) Molecular and Biochemical Parasitology , vol.136 , Issue.2 , pp. 273-285
    • Durrand, V.1    Berry, A.2    Sem, R.3    Glaziou, P.4    Beaudou, J.5    Fandeur, T.6
  • 31
    • 0027056692 scopus 로고
    • Chloroquine-resistant Plasmodium falciparum isolates from the Sudan lack two mutations in the pfmdr1 gene thought to be associated with chloroquine resistance
    • DOI 10.1016/0035-9203(92)90140-8
    • Chloroquine-resistant Plasmodium falciparum isolates from the Sudan lack two mutations in the pfmdr1 gene thought to be associated with chloroquine resistance. Awad-El-Kariem FM, Miles MA, Warhurst DC, Trans R Soc Trop Med Hyg 1992 86 587 589 10.1016/0035-9203(92)90140-8 1287907 (Pubitemid 23012895)
    • (1992) Transactions of the Royal Society of Tropical Medicine and Hygiene , vol.86 , Issue.6 , pp. 587-589
    • Awad-El-Kariem, F.M.1    Miles, M.A.2    Warhurst, D.C.3
  • 32
    • 0029586497 scopus 로고
    • Analysis of pfmdr1 and drug susceptibility in fresh isolates of Plasmodium falciparum from Subsaharan Africa
    • DOI 10.1016/0166-6851(95)02492-1
    • Analysis of pfmdr1 and drug susceptibility in fresh isolates of Plasmodium falciparum from Subsaharan Africa. Basco LK, Bras JL, Rhoades Z, Wilson CM, Mol Biochem Parasitol 1995 74 157 166 10.1016/0166-6851(95)02492-1 8719157 (Pubitemid 26024474)
    • (1995) Molecular and Biochemical Parasitology , vol.74 , Issue.2 , pp. 157-166
    • Basco, L.K.1    Le Bras, J.2    Rhoades, Z.3    Wilson, C.M.4
  • 36
    • 0034708162 scopus 로고    scopus 로고
    • Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum
    • DOI 10.1038/35002615
    • Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum. Reed MB, Saliba KJ, Caruana SR, Kirk K, Cowman AF, Nature 2000 403 906 909 10.1038/35002615 10706290 (Pubitemid 30130994)
    • (2000) Nature , vol.403 , Issue.6772 , pp. 906-909
    • Reed, M.B.1    Sallba, K.J.2    Caruana, S.R.3    Kirk, K.4    Cowman, A.F.5
  • 38
    • 33747157674 scopus 로고    scopus 로고
    • Association between mutations in Plasmodium falciparum chloroquine resistance transporter and P. falciparum multidrug resistance 1 genes and in vivo amodiaquine resistance in P. falciparum malaria-infected children in Nigeria
    • Association between mutations in Plasmodium falciparum chloroquine resistance transporter and Plasmodium falciparum multidrug resistance 1 genes and in vivo amodiaquine resistance in Plasmodium falciparum malaria-infected children in Nigeria. Happi CT, Gbotosho GO, Folarin OA, Bolaji OM, Sowunmi A, Kyle DE, Milhous W, Wirth DF, Oduola AM, Am J Trop Med Hyg 2006 75 155 161 16837724 (Pubitemid 351627586)
    • (2006) American Journal of Tropical Medicine and Hygiene , vol.75 , Issue.1 , pp. 155-161
    • Happi, C.T.1    Gbotosho, G.O.2    Folarin, O.A.3    Bolaji, O.M.4    Sowunmi, A.5    Kyle, D.E.6    Milhous, W.7    Wirth, D.F.8    Oduola, A.M.J.9
  • 39
    • 39849083920 scopus 로고    scopus 로고
    • Chloroquine-resistance molecular markers (Pfcrt T76 and Pfmdr-1 Y86) and amodiaquine resistance in Burkina Faso
    • DOI 10.1111/j.1365-3156.2007.01995.x
    • Chloroquine-resistance molecular markers (pfcrt T76 and pfmdr-1 Y86) and amodiaquine resistance in Burkina Faso. Tinto H, Guekoun L, Zongo I, Guiguemde RT, DAlessandro U, Ouedraogo JB, Trop Med Int Health 2008 13 238 240 10.1111/j.1365-3156.2007.01995.x 18304270 (Pubitemid 351316975)
    • (2008) Tropical Medicine and International Health , vol.13 , Issue.2 , pp. 238-240
    • Tinto, H.1    Guekoun, L.2    Zongo, I.3    Guiguemde, R.T.4    D'Alessandro, U.5    Ouedraogo, J.B.6
  • 40
    • 78751692553 scopus 로고    scopus 로고
    • Limited ability of Plasmodium falciparum pfcrt, pfmdr1, and pfnhe1 polymorphisms to predict quinine in vitro sensitivity or clinical effectiveness in Uganda
    • 10.1128/AAC.00954-10 21078941
    • Limited ability of Plasmodium falciparum pfcrt, pfmdr1, and pfnhe1 polymorphisms to predict quinine in vitro sensitivity or clinical effectiveness in Uganda. Baliraine FN, Nsobya SL, Achan J, Tibenderana JK, Talisuna AO, Greenhouse B, Rosenthal PJ, Antimicrob Agents Chemother 2011 55 615 622 10.1128/AAC.00954-10 21078941
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 615-622
    • Baliraine, F.N.1    Nsobya, S.L.2    Achan, J.3    Tibenderana, J.K.4    Talisuna, A.O.5    Greenhouse, B.6    Rosenthal, P.J.7
  • 41
    • 0034112601 scopus 로고    scopus 로고
    • Increased sensitivity to the antimalarials mefloquine and artemisinin is conferred by mutations in the pfmdr1 gene of Plasmodium falciparum
    • DOI 10.1046/j.1365-2958.2000.01914.x
    • Increased sensitivity to the antimalarials mefloquine and artemisinin is conferred by mutations in the pfmdr1 gene of Plasmodium falciparum. Duraisingh MT, Roper C, Walliker D, Warhurst DC, Mol Microbiol 2000 36 955 961 10.1046/j.1365-2958.2000.01914.x 10844681 (Pubitemid 30326539)
    • (2000) Molecular Microbiology , vol.36 , Issue.4 , pp. 955-961
    • Duraisingh, M.T.1    Roper, C.2    Walliker, D.3    Warhurst, D.C.4
  • 42
    • 23744435838 scopus 로고    scopus 로고
    • Pfmdr1 mutations contribute to quinine resistance and enhance mefloquine and artemisinin sensitivity in Plasmodium falciparum
    • DOI 10.1111/j.1365-2958.2005.04729.x
    • Pfmdr1 mutations contribute to quinine resistance and enhance mefloquine and artemisinin sensitivity in Plasmodium falciparum. Sidhu ABS, Valderramos SG, Fidock DA, Mol Microbiol 2005 57 913 926 10.1111/j.1365-2958.2005.04729.x 16091034 (Pubitemid 41139856)
    • (2005) Molecular Microbiology , vol.57 , Issue.4 , pp. 913-926
    • Sidhu, A.B.S.1    Valderramos, S.G.2    Fidock, D.A.3
  • 44
    • 22244435271 scopus 로고    scopus 로고
    • The roles of the pfcrt 76T and pfmdr1 86Y mutations, immunity and the initial level of parasitaemia, in predicting the outcome of chloroquine treatment in two areas with different transmission intensities
    • DOI 10.1179/136485905X46441
    • The roles of the pfcrt 76T and pfmdr1 86Y mutations, immunity and the initial level of parasitaemia, in predicting the outcome of chloroquine treatment in two areas with different transmission intensities. Khalil IF, Alifrangis M, Tarimo DS, Staalso T, Satti GMH, Theander TG, Ronn AM, Bygbjerg IC, Ann Trop Med Parasitol 2005 99 441 448 10.1179/136485905X46441 16004703 (Pubitemid 40992388)
    • (2005) Annals of Tropical Medicine and Parasitology , vol.99 , Issue.5 , pp. 441-448
    • Khalil, I.F.1    Alifrangis, M.2    Tarimo, D.S.3    Staalso, T.4    Satti, G.M.H.5    Theander, T.G.6    Ronn, A.M.7    Bygbjerg, I.C.8
  • 45
    • 0037317862 scopus 로고    scopus 로고
    • Association of Plasmodium falciparum chloroquine resistance transporter variant T76 with age-related plasma chloroquine levels
    • Association of Plasmodium falciparum chloroquine resistance transporter variant t76 with age-related plasma chloroquine levels. May J, Meyer CG, Am J Trop Med Hyg 2003 68 143 146 12641402 (Pubitemid 38240536)
    • (2003) American Journal of Tropical Medicine and Hygiene , vol.68 , Issue.2 , pp. 143-146
    • May, J.1    Meyer, C.G.2
  • 46
    • 30644474853 scopus 로고    scopus 로고
    • Drug resistance-virulence relationship in Plasmodium falciparum causing severe malaria in an area of seasonal and unstable transmission
    • DOI 10.1016/j.actatropica.2005.10.004, PII S0001706X05003268
    • Drug resistance-virulence relationship in Plasmodium falciparum causing severe malaria in an area of seasonal and unstable transmission. Giha HA, Elbashir MI, A-Elbasit IE, A-Elgadir TME, ElGhazali GE, Mackinnon MJ, Babiker HA, Acta Trop 2006 97 181 187 10.1016/j.actatropica.2005.10.004 16336938 (Pubitemid 43087752)
    • (2006) Acta Tropica , vol.97 , Issue.2 , pp. 181-187
    • Giha, H.A.1    Elbashir, M.I.2    A-Elbasit, I.E.3    A-Elgadir, T.M.E.4    ElGhazali, G.E.5    Mackinnon, M.J.6    Babiker, H.A.7
  • 47
    • 33845765162 scopus 로고    scopus 로고
    • No variation in the prevalence of point mutations in the Pfcrt and Pfmdr1 genes in isolates from Gabonese patients with uncomplicated or severe Plasmodium falciparum malaria
    • DOI 10.1007/s00436-006-0287-8
    • No variation in the prevalence of point mutations in the pfcrt and pfmdr1 genes in isolates from Gabonese patients with uncomplicated or severe Plasmodium falciparum malaria. Mayengue P, Kalmbach Y, Issifou S, Kremsner P, Ntoumi F, Parasitol Res 2007 100 487 493 17096149 (Pubitemid 46011259)
    • (2007) Parasitology Research , vol.100 , Issue.3 , pp. 487-493
    • Mayengue, P.I.1    Kalmbach, Y.2    Issifou, S.3    Kremsner, P.G.4    Ntoumi, F.5


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