A bipartite autoinhibitory region within the B-domain suppresses function in factor V

Journal of Biological Chemistry

Volumn 287, Issue 31, 2012, Pages 26342-26351

  Bos, Mettine H A ^a,c   Camire, Rodney M ^a,b  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD COAGULATION; COFACTORS; DRIVING FORCES; FACTOR XA; HIGH-AFFINITY BINDING SITES; KEY REACTIONS; REGULATORY REGIONS;

BIOCHEMISTRY; BIOLOGY;

BINDING SITES;

BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 5;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN MOTIF; SEQUENCE ANALYSIS; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; ANIMALS; BLOOD COAGULATION; CELLS, CULTURED; CONSERVED SEQUENCE; CRICETINAE; FACTOR V; HUMANS; MOLECULAR SEQUENCE DATA; PROTEIN PRECURSORS; PROTEIN STRUCTURE, TERTIARY; PROTHROMBIN TIME; RECOMBINANT PROTEINS; THROMBIN;

EID: 84864386285     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.377168     Document Type: Article

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