Characterization of a factor Xa binding site on factor Va near the Arg-506 activated protein C cleavage site

Journal of Biological Chemistry

Volumn 282, Issue 30, 2007, Pages 21848-21855

  Gale, Andrew J ^a   Yegneswaran, Subramanian ^a   Xu, Xiao ^a   Pellequer, Jean Luc ^b   Griffin, John H ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b CEA Marcoule   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITION; PARAMETER ESTIMATION; PEPTIDES; SPECTROSCOPIC ANALYSIS; TITRATION;

BINDING SEQUENCES; KINETIC MEASUREMENTS; SERINE PROTEASE FACTORS;

BINDING SITES;

ACTIVATED PROTEIN C; ARGININE; BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 5A; BLOOD CLOTTING FACTOR 8A; BLOOD CLOTTING FACTOR 9A; PHOSPHOLIPID; PROTHROMBIN; RECOMBINANT BLOOD CLOTTING FACTOR 8;

ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; KINETICS; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN STRUCTURE; PROTEIN VARIANT; SPECTROSCOPY;

AMINO ACID SUBSTITUTION; ANIMALS; ARGININE; BINDING SITES; CATTLE; CRYSTALLOGRAPHY, X-RAY; FACTOR VA; FACTOR XA; HUMANS; MUTAGENESIS, SITE-DIRECTED; PEPTIDE FRAGMENTS; PROTEIN C; PROTHROMBIN; RECOMBINANT PROTEINS; SEQUENCE DELETION; THROMBOPLASTIN;

EID: 34547599077     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M702192200     Document Type: Article

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