Methazolamide is a new hepatic insulin sensitizer that lowers blood glucose in vivo

Diabetes

Volumn 61, Issue 8, 2012, Pages 2146-2154

  Konstantopoulos, Nicky ^a   Molero, Juan C ^a   McGee, Sean L ^a   Spolding, Briana ^a   Connor, Tim ^a   De Vries, Melissa ^a   Wanyonyi, Stephen ^a   Fahey, Richard ^a   Morrison, Shona ^a   Swinton, Courtney ^a   Jones, Sharon ^a   Cooper, Adrian ^a   Garcia Guerra, Lucia ^a   Foletta, Victoria C ^a   Krippner, Guy ^b   Andrikopoulos, Sofianos ^c   Walder, Ken R ^a  

^a DEAKIN UNIVERSITY   (Australia)

^b Verva Pharmaceuticals   (Australia)

^c UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ACETAZOLAMIDE; CHLORTALIDONE; DICLOFENAMIDE; ETHOXZOLAMIDE; FUROSEMIDE; GLUCOSE; GLUCOSE 6 PHOSPHATASE; INSULIN; MESSENGER RNA; METFORMIN; METHAZOLAMIDE; PHOSPHOENOLPYRUVATE CARBOXYLASE; PYRUVIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDIABETIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DIET; DOSE RESPONSE; DRUG EFFECT; DRUG POTENTIATION; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; GLUCOSE CLAMP TECHNIQUE; GLUCOSE HOMEOSTASIS; GLUCOSE METABOLISM; GLUCOSE TOLERANCE; GLYCOLYSIS; IN VIVO STUDY; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INSULIN SENSITIVITY; INSULIN TOLERANCE TEST; MALE; MOUSE; NONHUMAN; OBESITY; OXYGEN CONSUMPTION; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; STREPTOZOCIN DIABETES;

ANIMALS; BLOOD GLUCOSE; CARBONIC ANHYDRASE INHIBITORS; DIABETES MELLITUS, EXPERIMENTAL; GLUCOSE CLAMP TECHNIQUE; GLUCOSE-6-PHOSPHATASE; GLYCOLYSIS; HOMEOSTASIS; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN RESISTANCE; LIVER; MALE; METFORMIN; METHAZOLAMIDE; MICE; MICE, INBRED C57BL; MICE, OBESE; OXYGEN CONSUMPTION; PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP); PYRUVIC ACID; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84864378844     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db11-0578     Document Type: Article

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