Focal adhesion kinase splice variants maintain primitive acute myeloid leukemia cells through altered Wnt signaling

Stem Cells

Volumn 30, Issue 8, 2012, Pages 1597-1610

  Despeaux, Mathieu ^a,b   Chicanne, Gaëtan ^b,c   Rouer, Evelyne ^d,e   De Toni Costes, Fabienne ^b,f   Bertrand, Jessica ^a,b   Mansat De Mas, Véronique ^b,f,g   Vergnolle, Nathalie ^a,b   Eaves, Connie ^h   Payrastre, Bernard ^b,c   Girault, Jean Antoine ^d,e   Racaud Sultan, Claire ^a,b  

^a INSERM   (France)

^b UNIVERSITÉ DE TOULOUSE   (France)

^c University Hospital of Toulouse   (France)

^d INSTITUT DU FER À MOULIN   (France)

^e SORBONNE UNIVERSITÉ   (France)

^f CANCER RESEARCH CENTER OF TOULOUSE   (France)

^g TOULOUSE UNIVERSITY HOSPITAL   (France)

^h BRITISH COLUMBIA CANCER AGENCY   (Canada)

Author keywords

Focal adhesion kinase; Leukemia; Splice variants; Stem cells; Wnt

Indexed keywords

BETA CATENIN; CD123 ANTIGEN; CD34 ANTIGEN; FOCAL ADHESION KINASE; FRIZZLED PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 5; WNT5A PROTEIN;

ACUTE GRANULOCYTIC LEUKEMIA; ADULT; AGED; ARTICLE; CLONOGENESIS; COMPLEX FORMATION; ENDOCYTOSIS; ENZYME PHOSPHORYLATION; FEMALE; HUMAN; HUMAN CELL; LEUKEMIA CELL; MALE; PROGNOSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; UPREGULATION;

AGED; ANTIGENS, CD34; BETA CATENIN; DISEASE-FREE SURVIVAL; FEMALE; FOCAL ADHESION PROTEIN-TYROSINE KINASES; FRIZZLED RECEPTORS; HUMANS; ISOENZYMES; LEUKEMIA, MYELOID, ACUTE; LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-6; MALE; MIDDLE AGED; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SURVIVAL ANALYSIS; TRANSCRIPTIONAL ACTIVATION; TRANSFECTION; WNT PROTEINS;

EID: 84864374811     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.1157     Document Type: Article

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