Specific deletion of focal adhesion kinase suppresses tumor formation and blocks malignant progression

Genes and Development

Volumn 18, Issue 24, 2004, Pages 2998-3003

  McLean, Gordon W ^a   Komiyama, Noboru H ^c,d   Serrels, Bryan ^a   Asano, Hidefumi ^d,g   Reynolds, Louise ^e   Conti, Francesco ^e   Hodivala Dilke, Kairbaan ^e   Metzger, Daniel ^f   Chambon, Pierre ^f   Grant, Seth G N ^c,d   Frame, Margaret C ^a,b  

^a BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^d UNIVERSITY OF EDINBURGH   (United Kingdom)

^e QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^f INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^g Chiba Kaihin Municipal Hospital   (Japan)

Author keywords

Apoptosis; Cancer; Conditional; Focal adhesion kinase; Keratinocyte

Indexed keywords

ESTROGEN RECEPTOR; FOCAL ADHESION KINASE; ISOPROTEIN; KERATIN; TAMOXIFEN;

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BENIGN TUMOR; CANCER GROWTH; CARCINOGENESIS; CELL DEATH; CELL MIGRATION; CONTROLLED STUDY; ENZYME ACTIVITY; EPIDERMIS; EPITHELIZATION; GENE DELETION; IN VITRO STUDY; IN VIVO STUDY; KERATINOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKIN TUMOR;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; DNA PRIMERS; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; FOCAL ADHESION KINASE 1; FOCAL ADHESION PROTEIN-TYROSINE KINASES; GENE DELETION; GENOTYPE; HYDROXYTESTOSTERONES; IMMUNOHISTOCHEMISTRY; INTEGRASES; KERATIN-14; KERATINOCYTES; KERATINS; MICE; MICE, TRANSGENIC; NEOPLASM METASTASIS; PROTEIN-TYROSINE KINASES; RECEPTORS, ESTROGEN; SKIN NEOPLASMS; TAMOXIFEN;

ANIMALIA;

EID: 10644280092     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.316304     Document Type: Article

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