Isolation, identification, and biological evaluation of Nrf2-ARE activator from the leaves of green perilla (Perilla frutescens var. crispa f. viridis)

Free Radical Biology and Medicine

Volumn 53, Issue 4, 2012, Pages 669-679

  Izumi, Yasuhiko ^a   Matsumura, Atsuko ^a   Wakita, Seiko ^a   Akagi, Ken Ichi ^b   Fukuda, Hiroyuki ^c   Kume, Toshiaki ^a   Irie, Kazuhiro ^a   Takada Takatori, Yuki ^d   Sugimoto, Hachiro ^e   Hashimoto, Tadashi ^c   Akaike, Akinori ^a,f  

^a KYOTO UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF BIOMEDICAL INNOVATION   (Japan)

^c Theravalues Corporation   (Japan)

^d DOSHISHA WOMEN'S COLLEGE OF LIBERAL ARTS   (Japan)

^e DOSHISHA UNIVERSITY   (Japan)

^f NAGOYA UNIVERSITY   (Japan)

Author keywords

6 Hydroxydopamine; Chalcone; Green perilla; Nrf2 ARE pathway; Oxidative stress

Indexed keywords

2',3' DIHYDROXY 4',6' DIMETHOXYCHALCONE; AMYGDALUS PERSICA EXTRACT; APIUM GRAVEOLENS EXTRACT; CHALCONE; CITRUS UNSHIU EXTRACT; CORCHORUS OLITORIUS EXTRACT; FRAGARIA EXTRACT; GLEBIONIS CORONARIA EXTRACT; GLUTAMATE CYSTEINE LIGASE; HEME OXYGENASE 1; MALUS PUMILA EXTRACT; MITOGEN ACTIVATED PROTEIN KINASE P38; OXIDOPAMINE; PERILLA FRUTESCENS EXTRACT; PETROSELIUM CRISPUM EXTRACT; PLANT EXTRACT; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); RUBUS IDAEUS EXTRACT; SULFORAPHANE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; VACCINIUM OXYCOCCOS;

ANIMAL CELL; ANTIOXIDANT RESPONSIVE ELEMENT; APPLE; ARTICLE; BIOLOGICAL ACTIVITY; CELERY; CELL PROTECTION; CONTROLLED STUDY; CORCHORUS OLITORIUS; DRUG CYTOTOXICITY; DRUG ISOLATION; ENZYME INHIBITION; FRACTIONATION; FRUIT; GLEBIONIS CORONARIA; MASS SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OXIDATIVE STRESS; PEACH; PERILLA FRUTESCENS; PETROSELIUM CRISPUM; PLANT LEAF; PRIORITY JOURNAL; PROTEIN EXPRESSION; RASPBERRY; RAT; SATSUMA; SIGNAL TRANSDUCTION; STRAWBERRY; TRANSCRIPTION INITIATION; VEGETABLE;

ANIMALS; ANTIOXIDANT RESPONSE ELEMENTS; CELL SURVIVAL; CHALCONES; CYTOPROTECTION; ENZYME INDUCTION; FRUIT; GENES, REPORTER; GLUTATHIONE; LUCIFERASES, FIREFLY; MOLECULAR STRUCTURE; NAD(P)H DEHYDROGENASE (QUINONE); NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PC12 CELLS; PERILLA FRUTESCENS; PLANT EXTRACTS; PLANT LEAVES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; REACTIVE OXYGEN SPECIES; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION; VEGETABLES;

PERILLA; PERILLA FRUTESCENS VAR. CRISPA;

EID: 84864368434     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2012.06.021     Document Type: Article

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