-
1
-
-
10344249918
-
Molecular regulation of the VEGF family - inducers of angiogenesis and lymphangiogenesis
-
McColl BK, Stacker SA, Achen MG. Molecular regulation of the VEGF family - inducers of angiogenesis and lymphangiogenesis. APMIS 2004; 112: 463-480.
-
(2004)
APMIS
, vol.112
, pp. 463-480
-
-
McColl, B.K.1
Stacker, S.A.2
Achen, M.G.3
-
2
-
-
34249689753
-
Molecular regulation of angiogenesis and lymphangiogenesis
-
Adams RH, Alitalo K. Molecular regulation of angiogenesis and lymphangiogenesis. Nat Rev Mol Cell Biol 2007; 8: 464-478.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 464-478
-
-
Adams, R.H.1
Alitalo, K.2
-
3
-
-
0242405617
-
Endothelial-pericyte interactions in angiogenesis
-
Gerhardt H, Betsholtz C. Endothelial-pericyte interactions in angiogenesis. Cell Tissue Res. 2003; 314: 15-23.
-
(2003)
Cell Tissue Res
, vol.314
, pp. 15-23
-
-
Gerhardt, H.1
Betsholtz, C.2
-
4
-
-
85013312416
-
Tumor angiogenesis: Therapeutic implications
-
Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med 1971; 285: 1182-1186.
-
(1971)
N Engl J Med
, vol.285
, pp. 1182-1186
-
-
Folkman, J.1
-
5
-
-
0030576517
-
Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
-
Hanahan D, Folkman J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 1996; 86: 353-364.
-
(1996)
Cell
, vol.86
, pp. 353-364
-
-
Hanahan, D.1
Folkman, J.2
-
6
-
-
0037967272
-
Tumorigenesis and the angiogenic switch
-
Bergers G, Benjamin LE. Tumorigenesis and the angiogenic switch. Nat Rev Cancer 2003; 3: 401-410.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 401-410
-
-
Bergers, G.1
Benjamin, L.E.2
-
7
-
-
12344312042
-
Cellular abnormalities of blood vessels as targets in cancer
-
Baluk P, Hashizume H, McDonald DM. Cellular abnormalities of blood vessels as targets in cancer. Curr Opin Genet Dev 2005; 15: 102-111.
-
(2005)
Curr Opin Genet Dev
, vol.15
, pp. 102-111
-
-
Baluk, P.1
Hashizume, H.2
McDonald, D.M.3
-
8
-
-
0033839080
-
Openings between defective endothelial cells explain tumor vessel leakiness
-
Hashizume H, Baluk P, Morikawa S, et al. Openings between defective endothelial cells explain tumor vessel leakiness. Am J Pathol 2000; 156: 1363-1380.
-
(2000)
Am J Pathol
, vol.156
, pp. 1363-1380
-
-
Hashizume, H.1
Baluk, P.2
Morikawa, S.3
-
9
-
-
0036124520
-
Abnormalities in pericytes on blood vessels and endothelial sprouts in tumors
-
Morikawa S, Baluk P, Kaidoh T, Haskell A, Jain RK, McDonald DM. Abnormalities in pericytes on blood vessels and endothelial sprouts in tumors. Am J Pathol 2002; 160: 985-1000.
-
(2002)
Am J Pathol
, vol.160
, pp. 985-1000
-
-
Morikawa, S.1
Baluk, P.2
Kaidoh, T.3
Haskell, A.4
Jain, R.K.5
McDonald, D.M.6
-
10
-
-
0036548794
-
Dissecting tumour pathophysiology using intravital microscopy
-
Jain RK, Munn LL, Fukumura D. Dissecting tumour pathophysiology using intravital microscopy. Nat Rev Cancer 2002; 2: 266-276.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 266-276
-
-
Jain, R.K.1
Munn, L.L.2
Fukumura, D.3
-
11
-
-
84975525035
-
Seminars in Medicine of the Beth Israel Hospital, Boston. Clinical applications of research on angiogenesis
-
Folkman J. Seminars in Medicine of the Beth Israel Hospital, Boston. Clinical applications of research on angiogenesis. N Engl J Med 1995; 333: 1757-1763.
-
(1995)
N Engl J Med
, vol.333
, pp. 1757-1763
-
-
Folkman, J.1
-
12
-
-
56749174211
-
FLT1 and its ligands VEGFB and PlGF: Drug targets for anti-angiogenic therapy?
-
Fischer C, Mazzone M, Jonckx B, Carmeliet P. FLT1 and its ligands VEGFB and PlGF: drug targets for anti-angiogenic therapy? Nat Rev Cancer. 2008; 8: 942-956.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 942-956
-
-
Fischer, C.1
Mazzone, M.2
Jonckx, B.3
Carmeliet, P.4
-
13
-
-
11444250615
-
Recent developments in the regulation of the angiogenic switch by cellular stress factors in tumors
-
North S, Moenner M, Bikfalvi A. Recent developments in the regulation of the angiogenic switch by cellular stress factors in tumors. Cancer Lett 2005; 218: 1-14.
-
(2005)
Cancer Lett
, vol.218
, pp. 1-14
-
-
North, S.1
Moenner, M.2
Bikfalvi, A.3
-
14
-
-
0026485002
-
Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
-
Shweiki D, Itin A, Soffer D, Keshet E. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature 1992; 359: 843-845.
-
(1992)
Nature
, vol.359
, pp. 843-845
-
-
Shweiki, D.1
Itin, A.2
Soffer, D.3
Keshet, E.4
-
15
-
-
0028822834
-
Mutant ras oncogenes upregulate VEGF/VPF expression: Implications for induction and inhibition of tumor angiogenesis
-
Rak J, Mitsuhashi Y, Bayko L, et al. Mutant ras oncogenes upregulate VEGF/VPF expression: implications for induction and inhibition of tumor angiogenesis. Cancer Res 1995; 55: 4575-4580.
-
(1995)
Cancer Res
, vol.55
, pp. 4575-4580
-
-
Rak, J.1
Mitsuhashi, Y.2
Bayko, L.3
-
16
-
-
0027958348
-
Mutant p53 potentiates protein kinase C induction of vascular endothelial growth factor expression
-
Kieser A, Weich HA, Brandner G, Marme D, Kolch W. Mutant p53 potentiates protein kinase C induction of vascular endothelial growth factor expression. Oncogene 1994; 9: 963-969.
-
(1994)
Oncogene
, vol.9
, pp. 963-969
-
-
Kieser, A.1
Weich, H.A.2
Brandner, G.3
Marme, D.4
Kolch, W.5
-
17
-
-
0027970092
-
Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma
-
O'Reilly MS, Holmgren L, Shing Y, et al. Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma. Cell 1994; 79: 315-328.
-
(1994)
Cell
, vol.79
, pp. 315-328
-
-
O'Reilly, M.S.1
Holmgren, L.2
Shing, Y.3
-
18
-
-
0031454617
-
Endostatin: An endogenous inhibitor of angiogenesis and tumor growth
-
O'Reilly MS, Boehm T, Shing Y, et al. Endostatin: an endogenous inhibitor of angiogenesis and tumor growth. Cell 1997; 88: 277-285.
-
(1997)
Cell
, vol.88
, pp. 277-285
-
-
O'Reilly, M.S.1
Boehm, T.2
Shing, Y.3
-
19
-
-
79959958353
-
Inhibition of tumor angiogenesis by antibodies, synthetic small molecules and natural products
-
Wahl O, Oswald M, Tretzel L, Herres E, Arend J, Efferth T. Inhibition of tumor angiogenesis by antibodies, synthetic small molecules and natural products. Curr Med Chem 2011; 18: 3136-3155.
-
(2011)
Curr Med Chem
, vol.18
, pp. 3136-3155
-
-
Wahl, O.1
Oswald, M.2
Tretzel, L.3
Herres, E.4
Arend, J.5
Efferth, T.6
-
21
-
-
65549139835
-
Lenalidomide: A novel anticancer drug with multiple modalities
-
Galustian C, Dalgleish A. Lenalidomide: a novel anticancer drug with multiple modalities. Expert Opin Pharmacother 2009; 10: 125-133.
-
(2009)
Expert Opin Pharmacother
, vol.10
, pp. 125-133
-
-
Galustian, C.1
Dalgleish, A.2
-
22
-
-
0038176480
-
Tumor response to ionizing radiation combined with antiangiogenesis or vascular targeting agents: Exploring mechanisms of interaction
-
Wachsberger P, Burd R, Dicker AP. Tumor response to ionizing radiation combined with antiangiogenesis or vascular targeting agents: exploring mechanisms of interaction. Clin Cancer Res 2003; 9: 1957-1971.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 1957-1971
-
-
Wachsberger, P.1
Burd, R.2
Dicker, A.P.3
-
23
-
-
67650667501
-
Molecular targets for tumor radiosensitization
-
Tofilon PJ, Camphausen K. Molecular targets for tumor radiosensitization. Chem Rev 2009; 109: 2974-2988.
-
(2009)
Chem Rev
, vol.109
, pp. 2974-2988
-
-
Tofilon, P.J.1
Camphausen, K.2
-
24
-
-
26444478703
-
Angiostatin's molecular mechanism: Aspects of specificity and regulation elucidated
-
Wahl ML, Kenan DJ, Gonzalez-Gronow M, Pizzo SV. Angiostatin's molecular mechanism: aspects of specificity and regulation elucidated. J Cell Biochem 2005; 96: 242-261.
-
(2005)
J Cell Biochem
, vol.96
, pp. 242-261
-
-
Wahl, M.L.1
Kenan, D.J.2
Gonzalez-Gronow, M.3
Pizzo, S.V.4
-
25
-
-
0030856731
-
Humanization of an antivascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders
-
Presta LG, Chen H, O'Connor SJ, et al. Humanization of an antivascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders. Cancer Res 1997; 57: 4593-4599.
-
(1997)
Cancer Res
, vol.57
, pp. 4593-4599
-
-
Presta, L.G.1
Chen, H.2
O'Connor, S.J.3
-
26
-
-
0026708632
-
The vascular endothelial growth factor proteins: Identification of biologically relevant regions by neutralizing monoclonal antibodies
-
Kim KJ, Li B, Houck K, Winer J, Ferrara N. The vascular endothelial growth factor proteins: identification of biologically relevant regions by neutralizing monoclonal antibodies. Growth Factors 1992; 7: 53-64.
-
(1992)
Growth Factors
, vol.7
, pp. 53-64
-
-
Kim, K.J.1
Li, B.2
Houck, K.3
Winer, J.4
Ferrara, N.5
-
27
-
-
65349186800
-
Aflibercept (AVE0005): An alternative strategy for inhibiting tumour angiogenesis by vascular endothelial growth factors
-
Chu QS. Aflibercept (AVE0005): an alternative strategy for inhibiting tumour angiogenesis by vascular endothelial growth factors. Expert Opin Biol Ther 2009; 9: 263-271.
-
(2009)
Expert Opin Biol Ther
, vol.9
, pp. 263-271
-
-
Chu, Q.S.1
-
28
-
-
0037143764
-
VEGF-Trap: A VEGF blocker with potent antitumor effects
-
Holash J, Davis S, Papadopoulos N, et al. VEGF-Trap: a VEGF blocker with potent antitumor effects. Proc Natl Acad Sci USA 2002; 99: 11393-11398.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 11393-11398
-
-
Holash, J.1
Davis, S.2
Papadopoulos, N.3
-
29
-
-
20144370978
-
AZD2171: A highly potent, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for the treatment of cancer
-
Wedge SR, Kendrew J, Hennequin LF, et al. AZD2171: a highly potent, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for the treatment of cancer. Cancer Res 2005; 65: 4389-4400.
-
(2005)
Cancer Res
, vol.65
, pp. 4389-4400
-
-
Wedge, S.R.1
Kendrew, J.2
Hennequin, L.F.3
-
30
-
-
4944249117
-
BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis
-
Wilhelm SM, Carter C, Tang L, et al. BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis. Cancer Res 2004; 64: 7099-7109.
-
(2004)
Cancer Res
, vol.64
, pp. 7099-7109
-
-
Wilhelm, S.M.1
Carter, C.2
Tang, L.3
-
32
-
-
77951544346
-
Anti-tumor effect of CT-322 as an adnectin inhibitor of vascular endothelial growth factor receptor-2
-
Mamluk R, Carvajal IM, Morse BA, et al. Anti-tumor effect of CT-322 as an adnectin inhibitor of vascular endothelial growth factor receptor-2. MAbs 2010; 2: 199-208.
-
(2010)
MAbs
, vol.2
, pp. 199-208
-
-
Mamluk, R.1
Carvajal, I.M.2
Morse, B.A.3
-
33
-
-
0029106167
-
In vitro neutralization of vascular endothelial growth factor activation of flk-1 by a monoclonal antibody
-
Rockwell P, Neufield G, Glassman A, Caron D, Goldstein N. In vitro neutralization of vascular endothelial growth factor activation of flk-1 by a monoclonal antibody. Mol Cell Differ 1995; 3: 91-109.
-
(1995)
Mol Cell Differ
, vol.3
, pp. 91-109
-
-
Rockwell, P.1
Neufield, G.2
Glassman, A.3
Caron, D.4
Goldstein, N.5
-
34
-
-
0034655182
-
PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration
-
Wood JM, Bold G, Buchdunger E, et al. PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration. Cancer Res 2000; 60: 2178-2189.
-
(2000)
Cancer Res
, vol.60
, pp. 2178-2189
-
-
Wood, J.M.1
Bold, G.2
Buchdunger, E.3
-
35
-
-
33748293111
-
SU14813: A novel multiple receptor tyrosine kinase inhibitor with potent antiangiogenic and antitumor activity
-
Patyna S, Laird AD, Mendel DB, et al. SU14813: a novel multiple receptor tyrosine kinase inhibitor with potent antiangiogenic and antitumor activity. Mol Cancer Ther 2006; 5: 1774-1782.
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 1774-1782
-
-
Patyna, S.1
Laird, A.D.2
Mendel, D.B.3
-
36
-
-
8444228524
-
The multi-targeted kinase inhibitor SU5416 inhibits small cell lung cancer growth and angiogenesis, in part by blocking Kit-mediated VEGF expression
-
Litz J, Sakuntala Warshamana-Greene G, Sulanke G, Lipson KE, Krystal GW. The multi-targeted kinase inhibitor SU5416 inhibits small cell lung cancer growth and angiogenesis, in part by blocking Kit-mediated VEGF expression. Lung Cancer 2004; 46: 283-291.
-
(2004)
Lung Cancer
, vol.46
, pp. 283-291
-
-
Litz, J.1
Sakuntala, W.-G.G.2
Sulanke, G.3
Lipson, K.E.4
Krystal, G.W.5
-
37
-
-
0035328851
-
Indolinone tyrosine kinase inhibitors block Kit activation and growth of small cell lung cancer cells
-
Krystal GW, Honsawek S, Kiewlich D, et al. Indolinone tyrosine kinase inhibitors block Kit activation and growth of small cell lung cancer cells. Cancer Res 2001; 61: 3660-368.
-
(2001)
Cancer Res
, vol.61
, pp. 3368-3660
-
-
Krystal, G.W.1
Honsawek, S.2
Kiewlich, D.3
-
38
-
-
0037108298
-
SU5416 and SU5614 inhibit kinase activity of wild-type and mutant FLT3 receptor tyrosine kinase
-
Yee KW, O'Farrell AM, Smolich BD, et al. SU5416 and SU5614 inhibit kinase activity of wild-type and mutant FLT3 receptor tyrosine kinase. Blood 2002; 100: 2941-2949.
-
(2002)
Blood
, vol.100
, pp. 2941-2949
-
-
Yee, K.W.1
O'Farrell, A.M.2
Smolich, B.D.3
-
39
-
-
0033883776
-
SU6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors
-
Laird AD, Vajkoczy P, Shawver LK, et al. SU6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors. Cancer Res 2000; 60: 4152-4160.
-
(2000)
Cancer Res
, vol.60
, pp. 4152-4160
-
-
Laird, A.D.1
Vajkoczy, P.2
Shawver, L.K.3
-
40
-
-
83355166909
-
Cabozantinib (XL184), a novel MET and VEGFR2 inhibitor, simultaneously suppresses metastasis, angiogenesis, and tumor growth
-
Yakes FM, Chen J, Tan J, et al. Cabozantinib (XL184), a novel MET and VEGFR2 inhibitor, simultaneously suppresses metastasis, angiogenesis, and tumor growth. Mol Cancer Ther 2011; 10: 2298-2308.
-
(2011)
Mol Cancer Ther
, vol.10
, pp. 2298-2308
-
-
Yakes, F.M.1
Chen, J.2
Tan, J.3
-
41
-
-
0037102369
-
ZD6474 inhibits vascular endothelial growth factor signaling, angiogenesis, and tumor growth following oral administration
-
Wedge SR, Ogilvie DJ, Dukes M, et al. ZD6474 inhibits vascular endothelial growth factor signaling, angiogenesis, and tumor growth following oral administration. Cancer Res 2002; 62: 4645-4655.
-
(2002)
Cancer Res
, vol.62
, pp. 4645-4655
-
-
Wedge, S.R.1
Ogilvie, D.J.2
Dukes, M.3
-
42
-
-
20944443196
-
Thrombospondin-1 mimetic peptide inhibitors of angiogenesis and tumor growth: Design, synthesis, and optimization of pharmacokinetics and biological activities
-
Haviv F, Bradley MF, Kalvin DM, et al. Thrombospondin-1 mimetic peptide inhibitors of angiogenesis and tumor growth: design, synthesis, and optimization of pharmacokinetics and biological activities. J Med Chem 2005; 48: 2838-2846.
-
(2005)
J Med Chem
, vol.48
, pp. 2838-2846
-
-
Haviv, F.1
Bradley, M.F.2
Kalvin, D.M.3
-
43
-
-
79952741178
-
Cilengitide: The first anti-angiogenic small molecule drug candidate design, synthesis and clinical evaluation
-
Mas-Moruno C, Rechenmacher F, Kessler H. Cilengitide: the first anti-angiogenic small molecule drug candidate design, synthesis and clinical evaluation. Anticancer Agents Med Chem 2010; 10: 753-768.
-
(2010)
Anticancer Agents Med Chem
, vol.10
, pp. 753-768
-
-
Mas-Moruno, C.1
Rechenmacher, F.2
Kessler, H.3
-
44
-
-
1542390673
-
Effects of thalidomide on the expression of angiogenesis growth factors in human A549 lung adenocarcinoma cells
-
Li X, Liu X, Wang J, et al. Effects of thalidomide on the expression of angiogenesis growth factors in human A549 lung adenocarcinoma cells. Int J Mol Med 2003; 11: 785-790.
-
(2003)
Int J Mol Med
, vol.11
, pp. 785-790
-
-
Li, X.1
Liu, X.2
Wang, J.3
-
45
-
-
0033564974
-
Blockage of the vascular endothelial growth factor stress response increases the antitumor effects of ionizing radiation
-
Gorski DH, Beckett MA, Jaskowiak NT, et al. Blockage of the vascular endothelial growth factor stress response increases the antitumor effects of ionizing radiation. Cancer Res 1999; 59: 3374-3378.
-
(1999)
Cancer Res
, vol.59
, pp. 3374-3378
-
-
Gorski, D.H.1
Beckett, M.A.2
Jaskowiak, N.T.3
-
46
-
-
19944426756
-
Thalidomide radiosensitizes tumors through early changes in the tumor microenvironment
-
Ansiaux R, Baudelet C, Jordan BF, et al. Thalidomide radiosensitizes tumors through early changes in the tumor microenvironment. Clin Cancer Res 2005; 11: 743-750.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 743-750
-
-
Ansiaux, R.1
Baudelet, C.2
Jordan, B.F.3
-
47
-
-
44349119079
-
SU11248 (sunitinib) sensitizes pancreatic cancer to the cytotoxic effects of ionizing radiation
-
Cuneo KC, Geng L, Fu A, Orton D, Hallahan DE, Chakravarthy AB. SU11248 (sunitinib) sensitizes pancreatic cancer to the cytotoxic effects of ionizing radiation. Int J Radiat Oncol Biol Phys 2008; 71: 873-879.
-
(2008)
Int J Radiat Oncol Biol Phys
, vol.71
, pp. 873-879
-
-
Cuneo, K.C.1
Geng, L.2
Fu, A.3
Orton, D.4
Hallahan, D.E.5
Chakravarthy, A.B.6
-
49
-
-
77957923161
-
Targeted therapies of cancer: Angiogenesis inhibition seems not enough
-
Roodink I, Leenders WP. Targeted therapies of cancer: angiogenesis inhibition seems not enough. Cancer Lett 2010; 299: 1-10.
-
(2010)
Cancer Lett
, vol.299
, pp. 1-10
-
-
Roodink, I.1
Leenders, W.P.2
-
50
-
-
0035987412
-
Angiogenesis inhibitors and radiotherapy of primary tumours
-
Camphausen K, Menard C. Angiogenesis inhibitors and radiotherapy of primary tumours. Expert Opin Biol Ther 2002; 2: 477-481.
-
(2002)
Expert Opin Biol Ther
, vol.2
, pp. 477-481
-
-
Camphausen, K.1
Menard, C.2
-
51
-
-
0003605672
-
-
Baltimore: Lippincott Williams and Wilkins, 6th Ed. Series
-
Hall E. Radiobiology for the Radiologist 6th ed. Series. Baltimore: Lippincott Williams and Wilkins; 2006
-
(2006)
Radiobiology For the Radiologist
-
-
Hall, E.1
-
52
-
-
0028305809
-
Potentiation of cytotoxic cancer therapies by TNP-470 alone and with other anti-angiogenic agents
-
Teicher BA, Holden SA, Ara G, et al. Potentiation of cytotoxic cancer therapies by TNP-470 alone and with other anti-angiogenic agents. Int J Cancer 1994; 57: 920-925.
-
(1994)
Int J Cancer
, vol.57
, pp. 920-925
-
-
Teicher, B.A.1
Holden, S.A.2
Ara, G.3
-
53
-
-
84982729034
-
Antiangiogenic Agents Can Increase Tumor Oxygenation and Response to Radiation Therapy
-
Teicher BA, Dupuis N, Kusomoto T, et al. Antiangiogenic Agents Can Increase Tumor Oxygenation and Response to Radiation Therapy. Radiat Oncol Invest 1995; 2: 269-276.
-
(1995)
Radiat Oncol Invest
, vol.2
, pp. 269-276
-
-
Teicher, B.A.1
Dupuis, N.2
Kusomoto, T.3
-
54
-
-
0024505574
-
Delivery of novel therapeutic agents in tumors: Physiological barriers and strategies
-
Jain RK. Delivery of novel therapeutic agents in tumors: physiological barriers and strategies. J Natl Cancer Inst 1989; 81: 570-576.
-
(1989)
J Natl Cancer Inst
, vol.81
, pp. 570-576
-
-
Jain, R.K.1
-
55
-
-
0034306974
-
Anti-Vascular endothelial growth factor treatment augments tumor radiation response under normoxic or hypoxic conditions
-
Lee CG, Heijn M, Di Tomaso E, et al. Anti-Vascular endothelial growth factor treatment augments tumor radiation response under normoxic or hypoxic conditions. Cancer Res 2000; 60: 5565-5570.
-
(2000)
Cancer Res
, vol.60
, pp. 5565-5570
-
-
Lee, C.G.1
Heijn, M.2
Di Tomaso, E.3
-
56
-
-
33745216415
-
Ionizing radiation antagonizes tumor hypoxia induced by antiangiogenic treatment
-
Riesterer O, Honer M, Jochum W, Oehler C, Ametamey S, Pruschy M. Ionizing radiation antagonizes tumor hypoxia induced by antiangiogenic treatment. Clin Cancer Res 2006; 12: 3518-3524.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 3518-3524
-
-
Riesterer, O.1
Honer, M.2
Jochum, W.3
Oehler, C.4
Ametamey, S.5
Pruschy, M.6
-
57
-
-
0035854479
-
Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice
-
Paris F, Fuks Z, Kang A, et al. Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice. Science 2001; 293: 293-297.
-
(2001)
Science
, vol.293
, pp. 293-297
-
-
Paris, F.1
Fuks, Z.2
Kang, A.3
-
58
-
-
0038626211
-
Tumor response to radiotherapy regulated by endothelial cell apoptosis
-
Garcia-Barros M, Paris F, Cordon-Cardo C, et al. Tumor response to radiotherapy regulated by endothelial cell apoptosis. Science 2003; 300: 1155-1159.
-
(2003)
Science
, vol.300
, pp. 1155-1159
-
-
Garcia-Barros, M.1
Paris, F.2
Cordon-Cardo, C.3
-
59
-
-
18244419396
-
Combined effects of angiostatin and ionizing radiation in antitumour therapy
-
Mauceri HJ, Hanna NN, Beckett MA, et al. Combined effects of angiostatin and ionizing radiation in antitumour therapy. Nature 1998; 394: 287-291.
-
(1998)
Nature
, vol.394
, pp. 287-291
-
-
Mauceri, H.J.1
Hanna, N.N.2
Beckett, M.A.3
-
60
-
-
12944331952
-
Combined effects of radiotherapy and angiostatin gene therapy in glioma tumor model
-
Griscelli F, Li H, Cheong C, et al. Combined effects of radiotherapy and angiostatin gene therapy in glioma tumor model. Proc Natl Acad Sci USA 2000; 97: 6698-6703.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 6698-6703
-
-
Griscelli, F.1
Li, H.2
Cheong, C.3
-
61
-
-
0035866771
-
Inhibition of vascular endothelial growth factor receptor signaling leads to reversal of tumor resistance to radiotherapy
-
Geng L, Donnelly E, McMahon G, et al. Inhibition of vascular endothelial growth factor receptor signaling leads to reversal of tumor resistance to radiotherapy. Cancer Res 2001; 61: 2413-2419.
-
(2001)
Cancer Res
, vol.61
, pp. 2413-2419
-
-
Geng, L.1
Donnelly, E.2
McMahon, G.3
-
62
-
-
0037085933
-
Simultaneous inhibition of the receptor kinase activity of vascular endothelial, fibroblast, and platelet-derived growth factors suppresses tumor growth and enhances tumor radiation response
-
Griffin RJ, Williams BW, Wild R, Cherrington JM, Park H, Song CW. Simultaneous inhibition of the receptor kinase activity of vascular endothelial, fibroblast, and platelet-derived growth factors suppresses tumor growth and enhances tumor radiation response. Cancer Res 2002; 62: 1702-1706.
-
(2002)
Cancer Res
, vol.62
, pp. 1702-1706
-
-
Griffin, R.J.1
Williams, B.W.2
Wild, R.3
Cherrington, J.M.4
Park, H.5
Song, C.W.6
-
63
-
-
0041672482
-
SU11248 maintenance therapy prevents tumor regrowth after fractionated irradiation of murine tumor models
-
Schueneman AJ, Himmelfarb E, Geng L, et al. SU11248 maintenance therapy prevents tumor regrowth after fractionated irradiation of murine tumor models. Cancer Res 2003; 63: 4009-4016.
-
(2003)
Cancer Res
, vol.63
, pp. 4009-4016
-
-
Schueneman, A.J.1
Himmelfarb, E.2
Geng, L.3
-
64
-
-
17444376781
-
Potentiation of the antitumor effect of ionizing radiation by brief concomitant exposures to angiostatin
-
Gorski DH, Mauceri HJ, Salloum RM, et al. Potentiation of the antitumor effect of ionizing radiation by brief concomitant exposures to angiostatin. Cancer Res 1998; 58: 5686-5689.
-
(1998)
Cancer Res
, vol.58
, pp. 5686-5689
-
-
Gorski, D.H.1
Mauceri, H.J.2
Salloum, R.M.3
-
65
-
-
20944448672
-
Trimodal cancer treatment: Beneficial effects of combined antiangiogenesis, radiation, and chemotherapy
-
Huber PE, Bischof M, Jenne J, et al. Trimodal cancer treatment: beneficial effects of combined antiangiogenesis, radiation, and chemotherapy. Cancer Res 2005; 65: 3643-3655.
-
(2005)
Cancer Res
, vol.65
, pp. 3643-3655
-
-
Huber, P.E.1
Bischof, M.2
Jenne, J.3
-
66
-
-
0033617532
-
Effects of angiogenesis inhibitors on multistage carcinogenesis in mice
-
Bergers G, Javaherian K, Lo KM, Folkman J, Hanahan D. Effects of angiogenesis inhibitors on multistage carcinogenesis in mice. Science 1999; 284: 808-812.
-
(1999)
Science
, vol.284
, pp. 808-812
-
-
Bergers, G.1
Javaherian, K.2
Lo, K.M.3
Folkman, J.4
Hanahan, D.5
-
67
-
-
0035819906
-
Effect of antiangiogenic therapy on slowly growing, poorly vascularized tumors in mice
-
Beecken WD, Fernandez A, Joussen AM, et al. Effect of antiangiogenic therapy on slowly growing, poorly vascularized tumors in mice. J Natl Cancer Inst 2001; 93: 382-387.
-
(2001)
J Natl Cancer Inst
, vol.93
, pp. 382-387
-
-
Beecken, W.D.1
Fernandez, A.2
Joussen, A.M.3
-
68
-
-
0036780251
-
Clinical translation of angiogenesis inhibitors
-
Kerbel R, Folkman J. Clinical translation of angiogenesis inhibitors. Nat Rev Cancer 2002; 2: 727-739.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 727-739
-
-
Kerbel, R.1
Folkman, J.2
-
69
-
-
0038298365
-
Phase I Trial Results of Recombinant Human Angiostatin Protein (rhA) and External Beam Radiation Therapy (EBRT)
-
Dicker AP, Anne R, Bonanni R, Sidor C, Gubish E, Curran WJ Jr. Phase I trial results of recombinant human angiostatin protein (rhA) and external beam radiation therapy (EBRT). 38th Annual Meeting of the American Association of Clinical Oncology 2002.
-
(2002)
38th Annual Meeting of the American Association of Clinical Oncology
-
-
Dicker, A.P.1
Anne, R.2
Bonanni, R.3
Sidor, C.4
Gubish, E.5
Curran Jr., W.J.6
-
70
-
-
11144354392
-
Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer
-
Willett CG, Boucher Y, Di Tomaso E, et al. Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer. Nat Med 2004; 10: 145-147.
-
(2004)
Nat Med
, vol.10
, pp. 145-147
-
-
Willett, C.G.1
Boucher, Y.2
Di Tomaso, E.3
-
71
-
-
30944452436
-
Surrogate markers for antiangiogenic therapy and dose-limiting toxicities for bevacizumab with radiation and chemotherapy: Continued experience of a phase I trial in rectal cancer patients
-
Willett CG, Boucher Y, Duda DG, et al. Surrogate markers for antiangiogenic therapy and dose-limiting toxicities for bevacizumab with radiation and chemotherapy: continued experience of a phase I trial in rectal cancer patients. J Clin Oncol 2005; 23: 8136-8139.
-
(2005)
J Clin Oncol
, vol.23
, pp. 8136-8139
-
-
Willett, C.G.1
Boucher, Y.2
Duda, D.G.3
-
72
-
-
67649921334
-
Efficacy, safety, and biomarkers of neoadjuvant bevacizumab, radiation therapy, and fluorouracil in rectal cancer: A multidisciplinary phase II study
-
Willett CG, Duda DG, Di Tomaso E, et al. Efficacy, safety, and biomarkers of neoadjuvant bevacizumab, radiation therapy, and fluorouracil in rectal cancer: a multidisciplinary phase II study. J Clin Oncol 2009; 27: 3020-3026.
-
(2009)
J Clin Oncol
, vol.27
, pp. 3020-3026
-
-
Willett, C.G.1
Duda, D.G.2
Di Tomaso, E.3
-
73
-
-
33644968548
-
Phase I trial evaluating the safety of bevacizumab with concurrent radiotherapy and capecitabine in locally advanced pancreatic cancer
-
Crane CH, Ellis LM, Abbruzzese JL, et al. Phase I trial evaluating the safety of bevacizumab with concurrent radiotherapy and capecitabine in locally advanced pancreatic cancer. J Clin Oncol 2006; 24: 1145-1151.
-
(2006)
J Clin Oncol
, vol.24
, pp. 1145-1151
-
-
Crane, C.H.1
Ellis, L.M.2
Abbruzzese, J.L.3
-
74
-
-
70249130566
-
Phase II study of bevacizumab with concurrent capecitabine and radiation followed by maintenance gemcitabine and bevacizumab for locally advanced pancreatic cancer: Radiation Therapy Oncology Group RTOG 0411
-
Crane CH, Winter K, Regine WF, et al. Phase II study of bevacizumab with concurrent capecitabine and radiation followed by maintenance gemcitabine and bevacizumab for locally advanced pancreatic cancer: Radiation Therapy Oncology Group RTOG 0411. J Clin Oncol 2009; 27: 4096-4102.
-
(2009)
J Clin Oncol
, vol.27
, pp. 4096-4102
-
-
Crane, C.H.1
Winter, K.2
Regine, W.F.3
-
75
-
-
68049091874
-
Chemoradiotherapy in gastrointestinal malignancies
-
Willett CG, Czito BG. Chemoradiotherapy in gastrointestinal malignancies. Clin Oncol (R Coll Radiol) 2009; 21: 543-556.
-
(2009)
Clin Oncol (R Coll Radiol)
, vol.21
, pp. 543-556
-
-
Willett, C.G.1
Czito, B.G.2
-
76
-
-
43249128897
-
Phase I study of bevacizumab added to fluorouracil- and hydroxyurea-based concomitant chemoradiotherapy for poor-prognosis head and neck cancer
-
Seiwert TY, Haraf DJ, Cohen EE, et al. Phase I study of bevacizumab added to fluorouracil- and hydroxyurea-based concomitant chemoradiotherapy for poor-prognosis head and neck cancer. J Clin Oncol 2008; 26: 1732-1741.
-
(2008)
J Clin Oncol
, vol.26
, pp. 1732-1741
-
-
Seiwert, T.Y.1
Haraf, D.J.2
Cohen, E.E.3
-
77
-
-
77955351554
-
Bevacizumab in combination with radiotherapy plus concomitant and adjuvant temozolomide for newly diagnosed glioblastoma: Update progression-free survival, overall survival, and toxicity
-
Gruber ML, Raza S, Gruber D, Narayana A. Bevacizumab in combination with radiotherapy plus concomitant and adjuvant temozolomide for newly diagnosed glioblastoma: Update progression-free survival, overall survival, and toxicity. J Clin Oncol 2009; 27: 15s.
-
(2009)
J Clin Oncol
, vol.27
-
-
Gruber, M.L.1
Raza, S.2
Gruber, D.3
Narayana, A.4
-
78
-
-
0033954292
-
Phase II trial of the antiangiogenic agent thalidomide in patients with recurrent highgrade gliomas
-
Fine HA, Figg WD, Jaeckle K, et al. Phase II trial of the antiangiogenic agent thalidomide in patients with recurrent highgrade gliomas. J Clin Oncol 2000; 18: 708-715.
-
(2000)
J Clin Oncol
, vol.18
, pp. 708-715
-
-
Fine, H.A.1
Figg, W.D.2
Jaeckle, K.3
-
79
-
-
0035191268
-
Phase II study of thalidomide in the treatment of recurrent glioblastoma multiforme
-
Marx GM, Pavlakis N, McCowatt S, et al. Phase II study of thalidomide in the treatment of recurrent glioblastoma multiforme. J Neurooncol 2001; 54: 31-38.
-
(2001)
J Neurooncol
, vol.54
, pp. 31-38
-
-
Marx, G.M.1
Pavlakis, N.2
McCowatt, S.3
-
80
-
-
4544289953
-
Phase II study of temozolomide and thalidomide with radiation therapy for newly diagnosed glioblastoma multiforme
-
Chang SM, Lamborn KR, Malec M, et al. Phase II study of temozolomide and thalidomide with radiation therapy for newly diagnosed glioblastoma multiforme. Int J Radiat Oncol Biol Phys 2004; 60: 353-357.
-
(2004)
Int J Radiat Oncol Biol Phys
, vol.60
, pp. 353-357
-
-
Chang, S.M.1
Lamborn, K.R.2
Malec, M.3
-
81
-
-
77955922743
-
Phase I study of vandetanib with radiotherapy and temozolomide for newly diagnosed glioblastoma
-
Drappatz J, Norden AD, Wong ET, et al. Phase I study of vandetanib with radiotherapy and temozolomide for newly diagnosed glioblastoma. Int J Radiat Oncol Biol Phys 2010; 78: 85-90.
-
(2010)
Int J Radiat Oncol Biol Phys
, vol.78
, pp. 85-90
-
-
Drappatz, J.1
Norden, A.D.2
Wong, E.T.3
-
82
-
-
84855842211
-
Study of Concomitant Thalidomide During Radiotherapy for Hepatocellular Carcinoma
-
Ch'ang HJ, Hsu C, Chen CH, Chang YH, Chang JS, Chen LT. Phase II Study of Concomitant Thalidomide During Radiotherapy for Hepatocellular Carcinoma. Int J Radiat Oncol Biol Phys 2011; 82: 817-825.
-
(2011)
Int J Radiat Oncol Biol Phys
, vol.82
, pp. 817-825
-
-
Ch'ang, H.J.1
Hsu, C.2
Chen, C.H.3
Chang, Y.H.4
Chang, J.S.5
Chen, L.T.6
Phase, I.I.7
-
83
-
-
77953653712
-
Angiogenic blockade and radiotherapy in hepatocellular carcinoma
-
Chi KH, Liao CS, Chang CC, et al. Angiogenic blockade and radiotherapy in hepatocellular carcinoma. Int J Radiat Oncol Biol Phys 2010; 78: 188-193.
-
(2010)
Int J Radiat Oncol Biol Phys
, vol.78
, pp. 188-193
-
-
Chi, K.H.1
Liao, C.S.2
Chang, C.C.3
-
84
-
-
68149170060
-
Phase 1 study of concurrent sunitinib and image-guided radiotherapy followed by maintenance sunitinib for patients with oligometastases: Acute toxicity and preliminary response
-
Kao J, Packer S, Vu HL, et al. Phase 1 study of concurrent sunitinib and image-guided radiotherapy followed by maintenance sunitinib for patients with oligometastases: acute toxicity and preliminary response. Cancer 2009; 115: 3571-3580.
-
(2009)
Cancer
, vol.115
, pp. 3571-3580
-
-
Kao, J.1
Packer, S.2
Vu, H.L.3
-
85
-
-
82955237229
-
A phase 1b trial of the combination of the antiangiogenic agent sunitinib and radiation therapy for patients with primary and metastatic central nervous system malignancies
-
Wuthrick EJ, Kamrava M, Curran WJ Jr., et al. A phase 1b trial of the combination of the antiangiogenic agent sunitinib and radiation therapy for patients with primary and metastatic central nervous system malignancies. Cancer 2011; 117(24): 5548-5559.
-
(2011)
Cancer
, vol.117
, Issue.24
, pp. 5548-5559
-
-
Wuthrick, E.J.1
Kamrava, M.2
Curran Jr., W.J.3
-
86
-
-
79951984402
-
Phase II study of bevacizumab plus temozolomide during and after radiation therapy for patients with newly diagnosed glioblastoma multiforme
-
Lai A, Tran A, Nghiemphu PL, et al. Phase II study of bevacizumab plus temozolomide during and after radiation therapy for patients with newly diagnosed glioblastoma multiforme. J Clin Oncol 2011; 29: 142-148.
-
(2011)
J Clin Oncol
, vol.29
, pp. 142-148
-
-
Lai, A.1
Tran, A.2
Nghiemphu, P.L.3
-
87
-
-
84856806386
-
A clinical trial of bevacizumab, temozolomide, and radiation for newly diagnosed glioblastoma
-
Narayana A, Gruber D, Kunnakkat S, et al. A clinical trial of bevacizumab, temozolomide, and radiation for newly diagnosed glioblastoma. J Neurosurg 2011; 116(2): 341-345.
-
(2011)
J Neurosurg
, vol.116
, Issue.2
, pp. 341-345
-
-
Narayana, A.1
Gruber, D.2
Kunnakkat, S.3
-
88
-
-
72549116624
-
Phase I/II trial of bevacizumab and radiotherapy for locally advanced inoperable colorectal cancer: Vasculature-independent radiosensitizing effect of bevacizumab
-
Koukourakis MI, Giatromanolaki A, Sheldon H, et al. Phase I/II trial of bevacizumab and radiotherapy for locally advanced inoperable colorectal cancer: vasculature-independent radiosensitizing effect of bevacizumab. Clin Cancer Res 2009; 15: 7069-7076.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 7069-7076
-
-
Koukourakis, M.I.1
Giatromanolaki, A.2
Sheldon, H.3
-
89
-
-
80053144167
-
A randomized phase II study of 5-fluorouracil, hydroxyurea, and twice-daily radiotherapy compared with bevacizumab plus 5-fluorouracil, hydroxyurea, and twice-daily radiotherapy for intermediate-stage and T4N0-1 head and neck cancers
-
Salama JK, Haraf DJ, Stenson KM, et al. A randomized phase II study of 5-fluorouracil, hydroxyurea, and twice-daily radiotherapy compared with bevacizumab plus 5-fluorouracil, hydroxyurea, and twice-daily radiotherapy for intermediate-stage and T4N0-1 head and neck cancers. Ann Oncol 2011; 22: 2304-2309.
-
(2011)
Ann Oncol
, vol.22
, pp. 2304-2309
-
-
Salama, J.K.1
Haraf, D.J.2
Stenson, K.M.3
-
90
-
-
80053149461
-
Phase I trial of bevacizumab followed by concurrent radiation, bevacizumab and cisplatin for locoregionally advanced squamous cell carcinoma of the head and neck
-
Harari PM, Traynor AM, Hoang T, et al. Phase I trial of bevacizumab followed by concurrent radiation, bevacizumab and cisplatin for locoregionally advanced squamous cell carcinoma of the head and neck. Int J Radiat Oncol Biol Phys 2010; 78: S104.
-
(2010)
Int J Radiat Oncol Biol Phys
, vol.78
-
-
Harari, P.M.1
Traynor, A.M.2
Hoang, T.3
-
91
-
-
77951448831
-
Phase II study of bevacizumab with docetaxel and radiation in locally advanced head and neck squamous cell cancer
-
Abstr 6071
-
Savvides PGJ, Bokar JA, Narayan A, et al. Phase II study of bevacizumab with docetaxel and radiation in locally advanced head and neck squamous cell cancer. J Clin Oncol 2008; 26(Suppl): (Abstr 6071).
-
(2008)
J Clin Oncol
, vol.26
, Issue.SUPPL.
-
-
Savvides, P.G.J.1
Bokar, J.A.2
Narayan, A.3
-
92
-
-
70350592108
-
Phase II study of bevacizumab (B) plus cisplatin (C) plus intensity-modulated radiation therapy (IMRT) for locoregionally advanced head and neck squamous cell cancer (HNSCC): Preliminary results
-
(Abstr 6013)
-
Pfister DG, Lee NY, Sherman E, et al. Phase II study of bevacizumab (B) plus cisplatin (C) plus intensity-modulated radiation therapy (IMRT) for locoregionally advanced head and neck squamous cell cancer (HNSCC): Preliminary results. J Clin Oncol 2009 27: 15s (Abstr 6013).
-
(2009)
J Clin Oncol
, vol.27
-
-
Pfister, D.G.1
Lee, N.Y.2
Sherman, E.3
-
93
-
-
73949149605
-
Tracheoesophageal fistula formation in patients with lung cancer treated with chemoradiation and bevacizumab
-
Spigel DR, Hainsworth JD, Yardley DA, et al. Tracheoesophageal fistula formation in patients with lung cancer treated with chemoradiation and bevacizumab. J Clin Oncol 2010; 28: 43-48.
-
(2010)
J Clin Oncol
, vol.28
, pp. 43-48
-
-
Spigel, D.R.1
Hainsworth, J.D.2
Yardley, D.A.3
-
94
-
-
84857914151
-
Phase II Study of Long-Term Androgen Suppression with Bevacizumab and Intensity-Modulated Radiation Therapy (IMRT) in High-Risk Prostate Cancer
-
Vuky J, Pham HT, Warren S, et al. Phase II Study of Long-Term Androgen Suppression with Bevacizumab and Intensity-Modulated Radiation Therapy (IMRT) in High-Risk Prostate Cancer. Int J Radiat Oncol Biol Phys 2011; 82(4): e609-615.
-
(2011)
Int J Radiat Oncol Biol Phys
, vol.82
, Issue.4
-
-
Vuky, J.1
Pham, H.T.2
Warren, S.3
-
95
-
-
34247848005
-
Bevacizumab, oxaliplatin, and capecitabine with radiation therapy in rectal cancer: Phase I trial results
-
Czito BG, Bendell JC, Willett CG, et al. Bevacizumab, oxaliplatin, and capecitabine with radiation therapy in rectal cancer: Phase I trial results. Int J Radiat Oncol Biol Phys 2007; 68: 472-478.
-
(2007)
Int J Radiat Oncol Biol Phys
, vol.68
, pp. 472-478
-
-
Czito, B.G.1
Bendell, J.C.2
Willett, C.G.3
-
96
-
-
79955642314
-
Bevacizumab, capecitabine, amifostine, and preoperative hypofractionated accelerated radiotherapy (HypoArc) for rectal cancer: A Phase II study
-
Koukourakis MI, Giatromanolaki A, Tsoutsou P, et al. Bevacizumab, capecitabine, amifostine, and preoperative hypofractionated accelerated radiotherapy (HypoArc) for rectal cancer: a Phase II study. Int J Radiat Oncol Biol Phys 2011; 80: 492-498.
-
(2011)
Int J Radiat Oncol Biol Phys
, vol.80
, pp. 492-498
-
-
Koukourakis, M.I.1
Giatromanolaki, A.2
Tsoutsou, P.3
-
97
-
-
76049088643
-
Phase II trial of neoadjuvant bevacizumab, capecitabine, and radiotherapy for locally advanced rectal cancer
-
Crane CH, Eng C, Feig BW, et al. Phase II trial of neoadjuvant bevacizumab, capecitabine, and radiotherapy for locally advanced rectal cancer. Int J Radiat Oncol Biol Phys 2010; 76: 824-830.
-
(2010)
Int J Radiat Oncol Biol Phys
, vol.76
, pp. 824-830
-
-
Crane, C.H.1
Eng, C.2
Feig, B.W.3
-
98
-
-
83255194188
-
Pre-operative bevacizumab, capecitabine, oxaliplatin and radiation among patients with locally advanced or low rectal cancer: A phase II trial
-
Kennecke H, Berry S, Wong R, et al. Pre-operative bevacizumab, capecitabine, oxaliplatin and radiation among patients with locally advanced or low rectal cancer: A phase II trial. Eur J Cancer 2012; 48: 37-45.
-
(2012)
Eur J Cancer
, vol.48
, pp. 37-45
-
-
Kennecke, H.1
Berry, S.2
Wong, R.3
-
99
-
-
72449155176
-
EORTC study 26041-22041: Phase I/II study on concomitant and adjuvant temozolomide (TMZ) and radiotherapy (RT) with PTK787/ZK222584 (PTK/ZK) in newly diagnosed glioblastoma
-
Brandes AA, Stupp R, Hau P, et al. EORTC study 26041-22041: phase I/II study on concomitant and adjuvant temozolomide (TMZ) and radiotherapy (RT) with PTK787/ZK222584 (PTK/ZK) in newly diagnosed glioblastoma. Eur J Cancer 2010; 46: 348-354.
-
(2010)
Eur J Cancer
, vol.46
, pp. 348-354
-
-
Brandes, A.A.1
Stupp, R.2
Hau, P.3
-
100
-
-
77749332056
-
A phase 1 trial of ABT-510 concurrent with standard chemoradiation for patients with newly diagnosed glioblastoma
-
Nabors LB, Fiveash JB, Markert JM, et al. A phase 1 trial of ABT-510 concurrent with standard chemoradiation for patients with newly diagnosed glioblastoma. Arch Neurol 2010; 67: 313-319.
-
(2010)
Arch Neurol
, vol.67
, pp. 313-319
-
-
Nabors, L.B.1
Fiveash, J.B.2
Markert, J.M.3
-
101
-
-
79952188499
-
A prospective study of temozolomide plus thalidomide during and after radiation therapy for pediatric diffuse pontine gliomas: Preliminary results of the Korean Society for Pediatric Neuro-Oncology study
-
Kim CY, Kim SK, Phi JH, et al. A prospective study of temozolomide plus thalidomide during and after radiation therapy for pediatric diffuse pontine gliomas: preliminary results of the Korean Society for Pediatric Neuro-Oncology study. J Neurooncol 2010; 100: 193-198.
-
(2010)
J Neurooncol
, vol.100
, pp. 193-198
-
-
Kim, C.Y.1
Kim, S.K.2
Phi, J.H.3
-
102
-
-
33846992324
-
Phase II study of thalidomide and radiation in children with newly diagnosed brain stem gliomas and glioblastoma multiforme
-
Turner CD, Chi S, Marcus KJ, et al. Phase II study of thalidomide and radiation in children with newly diagnosed brain stem gliomas and glioblastoma multiforme. J Neurooncol 2007; 82: 95-101.
-
(2007)
J Neurooncol
, vol.82
, pp. 95-101
-
-
Turner, C.D.1
Chi, S.2
Marcus, K.J.3
-
103
-
-
55749092775
-
Temozolomide, thalidomide, and whole brain radiation therapy for patients with brain metastasis from metastatic melanoma: A phase II Cytokine Working Group study
-
Atkins MB, Sosman JA, Agarwala S, et al. Temozolomide, thalidomide, and whole brain radiation therapy for patients with brain metastasis from metastatic melanoma: a phase II Cytokine Working Group study. Cancer 2008; 113: 2139-2145.
-
(2008)
Cancer
, vol.113
, pp. 2139-2145
-
-
Atkins, M.B.1
Sosman, J.A.2
Agarwala, S.3
-
104
-
-
41749108387
-
A phase III study of conventional radiation therapy plus thalidomide versus conventional radiation therapy for multiple brain metastases (RTOG 0118)
-
Knisely JP, Berkey B, Chakravarti A, et al. A phase III study of conventional radiation therapy plus thalidomide versus conventional radiation therapy for multiple brain metastases (RTOG 0118). Int J Radiat Oncol Biol Phys 2008; 71: 79-86.
-
(2008)
Int J Radiat Oncol Biol Phys
, vol.71
, pp. 79-86
-
-
Knisely, J.P.1
Berkey, B.2
Chakravarti, A.3
-
105
-
-
57649110848
-
A pilot safety study of lenalidomide and radiotherapy for patients with newly diagnosed glioblastoma multiforme
-
Drappatz J, Wong ET, Schiff D, et al. A pilot safety study of lenalidomide and radiotherapy for patients with newly diagnosed glioblastoma multiforme. Int J Radiat Oncol Biol Phys 2009; 73: 222-227.
-
(2009)
Int J Radiat Oncol Biol Phys
, vol.73
, pp. 222-227
-
-
Drappatz, J.1
Wong, E.T.2
Schiff, D.3
-
106
-
-
29244453204
-
Combining radiotherapy and angiogenesis inhibitors: Clinical trial design
-
Citrin D, Menard C, Camphausen K. Combining radiotherapy and angiogenesis inhibitors: clinical trial design. Int J Radiat Oncol Biol Phys 2006; 64: 15-25.
-
(2006)
Int J Radiat Oncol Biol Phys
, vol.64
, pp. 15-25
-
-
Citrin, D.1
Menard, C.2
Camphausen, K.3
-
107
-
-
0035865450
-
Clinical implications of circulating angiogenic factors in cancer patients
-
Poon RT, Fan ST, Wong J. Clinical implications of circulating angiogenic factors in cancer patients. J Clin Oncol 2001; 19: 1207-1225.
-
(2001)
J Clin Oncol
, vol.19
, pp. 1207-1225
-
-
Poon, R.T.1
Fan, S.T.2
Wong, J.3
-
108
-
-
80055036400
-
Biomarkers in tumor angiogenesis and anti-angiogenic therapy
-
Pircher A, Hilbe W, Heidegger I, Drevs J, Tichelli A, Medinger M. Biomarkers in tumor angiogenesis and anti-angiogenic therapy. Int J Mol Sci 2011; 12: 7077-7099.
-
(2011)
Int J Mol Sci
, vol.12
, pp. 7077-7099
-
-
Pircher, A.1
Hilbe, W.2
Heidegger, I.3
Drevs, J.4
Tichelli, A.5
Medinger, M.6
-
110
-
-
2342663709
-
Molecular imaging of tumor angiogenesis
-
Schirner M, Menrad A, Stephens A, Frenzel T, Hauff P, Licha K. Molecular imaging of tumor angiogenesis. Ann NY Acad Sci 2004; 1014: 67-75.
-
(2004)
Ann NY Acad Sci
, vol.1014
, pp. 67-75
-
-
Schirner, M.1
Menrad, A.2
Stephens, A.3
Frenzel, T.4
Hauff, P.5
Licha, K.6
-
111
-
-
33845771272
-
Imaging of angiogenesis: Clinical techniques and novel imaging methods
-
Provenzale JM. Imaging of angiogenesis: clinical techniques and novel imaging methods. AJR Am J Roentgenol 2007; 188: 11-23.
-
(2007)
AJR Am J Roentgenol
, vol.188
, pp. 11-23
-
-
Provenzale, J.M.1
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