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Volumn 27, Issue 8, 2012, Pages 1680-1694

Cartilage-specific β-catenin signaling regulates chondrocyte maturation, generation of ossification centers, and perichondrial bone formation during skeletal development

Author keywords

CATENIN; CARTILAGE; CHONDROCYTE; PERICHONDRIUM; SKELETAL DEVELOPMENT

Indexed keywords

BETA CATENIN; BONE MORPHOGENETIC PROTEIN 2; MATRIX METALLOPROTEINASE; SONIC HEDGEHOG PROTEIN; TAMOXIFEN;

EID: 84864145218     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.1639     Document Type: Article
Times cited : (118)

References (61)
  • 2
    • 34447639266 scopus 로고    scopus 로고
    • Tamoxifen-inducible gene deletion reveals a distinct cell type associated with trabecular bone, and direct regulation of PTHrP expression and chondrocyte morphology by Ihh in growth region cartilage
    • Aug 1;.
    • Hilton MJ, Tu X, Long F., Tamoxifen-inducible gene deletion reveals a distinct cell type associated with trabecular bone, and direct regulation of PTHrP expression and chondrocyte morphology by Ihh in growth region cartilage. Dev Biol. 2007 Aug 1; 308 (1): 93-105.
    • (2007) Dev Biol. , vol.308 , Issue.1 , pp. 93-105
    • Hilton, M.J.1    Tu, X.2    Long, F.3
  • 3
    • 0029611033 scopus 로고
    • Tissue-specific regulation of the type X collagen gene. Analyses by in vivo footprinting and transfection with a proximal promoter region
    • Dec 29;.
    • Long F, Linsenmayer TF., Tissue-specific regulation of the type X collagen gene. Analyses by in vivo footprinting and transfection with a proximal promoter region. J Biol Chem. 1995 Dec 29; 270 (52): 31310-4.
    • (1995) J Biol Chem. , vol.270 , Issue.52 , pp. 31310-31314
    • Long, F.1    Linsenmayer, T.F.2
  • 4
    • 1842766265 scopus 로고    scopus 로고
    • Distinguishing the contributions of the perichondrium, cartilage, and vascular endothelium to skeletal development
    • May 1;.
    • Colnot C, Lu C, Hu D, Helms JA., Distinguishing the contributions of the perichondrium, cartilage, and vascular endothelium to skeletal development. Dev Biol. 2004 May 1; 269 (1): 55-69.
    • (2004) Dev Biol. , vol.269 , Issue.1 , pp. 55-69
    • Colnot, C.1    Lu, C.2    Hu, D.3    Helms, J.A.4
  • 5
    • 21244482087 scopus 로고    scopus 로고
    • Chondrocytes are released as viable cells during cartilage resorption associated with the formation of intrachondral canals in the rat tibial epiphysis
    • Jun;.
    • Alvarez J, Costales L, Lopez-Muniz A, Lopez JM., Chondrocytes are released as viable cells during cartilage resorption associated with the formation of intrachondral canals in the rat tibial epiphysis. Cell Tissue Res. 2005 Jun; 320 (3): 501-7.
    • (2005) Cell Tissue Res. , vol.320 , Issue.3 , pp. 501-507
    • Alvarez, J.1    Costales, L.2    Lopez-Muniz, A.3    Lopez, J.M.4
  • 6
    • 19044364979 scopus 로고    scopus 로고
    • Expression patterns of matrix metalloproteinases and vascular endothelial growth factor during epiphyseal ossification
    • Jun;.
    • Alvarez J, Costales L, Serra R, Balbin M, Lopez JM., Expression patterns of matrix metalloproteinases and vascular endothelial growth factor during epiphyseal ossification. J Bone Miner Res. 2005 Jun; 20 (6): 1011-21.
    • (2005) J Bone Miner Res. , vol.20 , Issue.6 , pp. 1011-1021
    • Alvarez, J.1    Costales, L.2    Serra, R.3    Balbin, M.4    Lopez, J.M.5
  • 7
    • 48149087435 scopus 로고    scopus 로고
    • Structure, formation and role of cartilage canals in the developing bone
    • Blumer MJ, Longato S, Fritsch H., Structure, formation and role of cartilage canals in the developing bone. Ann Anat. 2008; 190 (4): 305-15.
    • (2008) Ann Anat. , vol.190 , Issue.4 , pp. 305-315
    • Blumer, M.J.1    Longato, S.2    Fritsch, H.3
  • 8
    • 0028299540 scopus 로고
    • Development of the cartilage canals and the secondary center of ossification in the distal chondroepiphysis of the prenatal human femur
    • May-Jun;.
    • Burkus JK, Ganey TM, Ogden JA., Development of the cartilage canals and the secondary center of ossification in the distal chondroepiphysis of the prenatal human femur. Yale J Biol Med. 1993 May-Jun; 66 (3): 193-202.
    • (1993) Yale J Biol Med. , vol.66 , Issue.3 , pp. 193-202
    • Burkus, J.K.1    Ganey, T.M.2    Ogden, J.A.3
  • 9
    • 17844372752 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis
    • May;.
    • Day TF, Guo X, Garrett-Beal L, Yang Y., Wnt/beta-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis. Dev Cell. 2005 May; 8 (5): 739-50.
    • (2005) Dev Cell. , vol.8 , Issue.5 , pp. 739-750
    • Day, T.F.1    Guo, X.2    Garrett-Beal, L.3    Yang, Y.4
  • 10
    • 17844363974 scopus 로고    scopus 로고
    • Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes
    • May;.
    • Hill TP, Spater D, Taketo MM, Birchmeier W, Hartmann C., Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes. Dev Cell. 2005 May; 8 (5): 727-38.
    • (2005) Dev Cell. , vol.8 , Issue.5 , pp. 727-738
    • Hill, T.P.1    Spater, D.2    Taketo, M.M.3    Birchmeier, W.4    Hartmann, C.5
  • 11
    • 33646130168 scopus 로고    scopus 로고
    • Multiple roles of mesenchymal beta-catenin during murine limb patterning
    • Apr;.
    • Hill TP, Taketo MM, Birchmeier W, Hartmann C., Multiple roles of mesenchymal beta-catenin during murine limb patterning. Development. 2006 Apr; 133 (7): 1219-29.
    • (2006) Development. , vol.133 , Issue.7 , pp. 1219-1229
    • Hill, T.P.1    Taketo, M.M.2    Birchmeier, W.3    Hartmann, C.4
  • 13
    • 67649484495 scopus 로고    scopus 로고
    • The Wnt/beta-catenin pathway interacts differentially with PTHrP signaling to control chondrocyte hypertrophy and final maturation
    • Guo X, Mak KK, Taketo MM, Yang Y., The Wnt/beta-catenin pathway interacts differentially with PTHrP signaling to control chondrocyte hypertrophy and final maturation. PLoS One. 2009; 4 (6): e6067.
    • (2009) PLoS One. , vol.4 , Issue.6
    • Guo, X.1    Mak, K.K.2    Taketo, M.M.3    Yang, Y.4
  • 14
    • 0033864484 scopus 로고    scopus 로고
    • Dual roles of Wnt signaling during chondrogenesis in the chicken limb
    • Jul;.
    • Hartmann C, Tabin CJ., Dual roles of Wnt signaling during chondrogenesis in the chicken limb. Development. 2000 Jul; 127 (14): 3141-59.
    • (2000) Development. , vol.127 , Issue.14 , pp. 3141-3159
    • Hartmann, C.1    Tabin, C.J.2
  • 15
    • 13444302715 scopus 로고    scopus 로고
    • Sequential roles of Hedgehog and Wnt signaling in osteoblast development
    • Jan;.
    • Hu H, Hilton MJ, Tu X, Yu K, Ornitz DM, Long F., Sequential roles of Hedgehog and Wnt signaling in osteoblast development. Development. 2005 Jan; 132 (1): 49-60.
    • (2005) Development. , vol.132 , Issue.1 , pp. 49-60
    • Hu, H.1    Hilton, M.J.2    Tu, X.3    Yu, K.4    Ornitz, D.M.5    Long, F.6
  • 18
    • 38349143951 scopus 로고    scopus 로고
    • Tamoxifen-inducible Cre-recombination in articular chondrocytes of adult Col2a1-CreER(T2) transgenic mice
    • Jan;.
    • Zhu M, Chen M, Lichtler AC, O'Keefe RJ, Chen D., Tamoxifen-inducible Cre-recombination in articular chondrocytes of adult Col2a1-CreER(T2) transgenic mice. Osteoarthritis Cartilage. 2008 Jan; 16 (1): 129-30.
    • (2008) Osteoarthritis Cartilage. , vol.16 , Issue.1 , pp. 129-130
    • Zhu, M.1    Chen, M.2    Lichtler, A.C.3    O'Keefe, R.J.4    Chen, D.5
  • 19
    • 33846815207 scopus 로고    scopus 로고
    • Generation of a transgenic mouse model with chondrocyte-specific and tamoxifen-inducible expression of Cre recombinase
    • Jan;.
    • Chen M, Lichtler AC, Sheu TJ, Xie C, Zhang X, O'Keefe RJ, Chen D., Generation of a transgenic mouse model with chondrocyte-specific and tamoxifen-inducible expression of Cre recombinase. Genesis. 2007 Jan; 45 (1): 44-50.
    • (2007) Genesis. , vol.45 , Issue.1 , pp. 44-50
    • Chen, M.1    Lichtler, A.C.2    Sheu, T.J.3    Xie, C.4    Zhang, X.5    O'Keefe, R.J.6    Chen, D.7
  • 20
    • 0035034603 scopus 로고    scopus 로고
    • Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development
    • Apr;.
    • Brault V, Moore R, Kutsch S, Ishibashi M, Rowitch DH, McMahon AP, Sommer L, Boussadia O, Kemler R., Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development. Development. 2001 Apr; 128 (8): 1253-64.
    • (2001) Development. , vol.128 , Issue.8 , pp. 1253-1264
    • Brault, V.1    Moore, R.2    Kutsch, S.3    Ishibashi, M.4    Rowitch, D.H.5    McMahon, A.P.6    Sommer, L.7    Boussadia, O.8    Kemler, R.9
  • 21
    • 0033230616 scopus 로고    scopus 로고
    • Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene
    • Nov 1;.
    • Harada N, Tamai Y, Ishikawa T, Sauer B, Takaku K, Oshima M, Taketo MM., Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene. EMBO J. 1999 Nov 1; 18 (21): 5931-42.
    • (1999) EMBO J. , vol.18 , Issue.21 , pp. 5931-5942
    • Harada, N.1    Tamai, Y.2    Ishikawa, T.3    Sauer, B.4    Takaku, K.5    Oshima, M.6    Taketo, M.M.7
  • 23
    • 27644467931 scopus 로고    scopus 로고
    • Ihh controls cartilage development by antagonizing Gli3, but requires additional effectors to regulate osteoblast and vascular development
    • Oct;.
    • Hilton MJ, Tu X, Cook J, Hu H, Long F., Ihh controls cartilage development by antagonizing Gli3, but requires additional effectors to regulate osteoblast and vascular development. Development. 2005 Oct; 132 (19): 4339-51.
    • (2005) Development. , vol.132 , Issue.19 , pp. 4339-4351
    • Hilton, M.J.1    Tu, X.2    Cook, J.3    Hu, H.4    Long, F.5
  • 25
    • 0028071586 scopus 로고
    • Characterization of primary cultures of chondrocytes from type II collagen/beta-galactosidase transgenic mice
    • Aug;.
    • Lefebvre V, Garofalo S, Zhou G, Metsaranta M, Vuorio E, De Crombrugghe B., Characterization of primary cultures of chondrocytes from type II collagen/beta-galactosidase transgenic mice. Matrix Biol. 1994 Aug; 14 (4): 329-35.
    • (1994) Matrix Biol. , vol.14 , Issue.4 , pp. 329-335
    • Lefebvre, V.1    Garofalo, S.2    Zhou, G.3    Metsaranta, M.4    Vuorio, E.5    De Crombrugghe, B.6
  • 26
    • 0034866208 scopus 로고    scopus 로고
    • Enzymes active in the areas undergoing cartilage resorption during the development of the secondary ossification center in the tibiae of rats ages 0-21 days: I. Two groups of proteinases cleave the core protein of aggrecan
    • Sep;.
    • Lee ER, Lamplugh L, Davoli MA, Beauchemin A, Chan K, Mort JS, Leblond CP., Enzymes active in the areas undergoing cartilage resorption during the development of the secondary ossification center in the tibiae of rats ages 0-21 days: I. Two groups of proteinases cleave the core protein of aggrecan. Dev Dyn. 2001 Sep; 222 (1): 52-70.
    • (2001) Dev Dyn. , vol.222 , Issue.1 , pp. 52-70
    • Lee, E.R.1    Lamplugh, L.2    Davoli, M.A.3    Beauchemin, A.4    Chan, K.5    Mort, J.S.6    Leblond, C.P.7
  • 27
    • 70649094222 scopus 로고    scopus 로고
    • BMP2 signaling in bone development and repair
    • Oct-Dec;.
    • Rosen V., BMP2 signaling in bone development and repair. Cytokine Growth Factor Rev. 2009 Oct-Dec; 20 (5-6): 475-80.
    • (2009) Cytokine Growth Factor Rev. , vol.20 , Issue.56 , pp. 475-480
    • Rosen, V.1
  • 30
    • 34447343823 scopus 로고    scopus 로고
    • Bone morphogenetic proteins in clinical applications
    • Aug;.
    • Gautschi OP, Frey SP, Zellweger R., Bone morphogenetic proteins in clinical applications. ANZ J Surg. 2007 Aug; 77 (8): 626-31.
    • (2007) ANZ J Surg. , vol.77 , Issue.8 , pp. 626-631
    • Gautschi, O.P.1    Frey, S.P.2    Zellweger, R.3
  • 33
    • 33846987195 scopus 로고    scopus 로고
    • Beta-catenin signaling pathway is crucial for bone morphogenetic protein 2 to induce new bone formation
    • Jan 5;.
    • Chen Y, Whetstone HC, Youn A, Nadesan P, Chow EC, Lin AC, Alman BA., Beta-catenin signaling pathway is crucial for bone morphogenetic protein 2 to induce new bone formation. J Biol Chem. 2007 Jan 5; 282 (1): 526-33.
    • (2007) J Biol Chem. , vol.282 , Issue.1 , pp. 526-533
    • Chen, Y.1    Whetstone, H.C.2    Youn, A.3    Nadesan, P.4    Chow, E.C.5    Lin, A.C.6    Alman, B.A.7
  • 34
    • 58149097603 scopus 로고    scopus 로고
    • Activation of beta-catenin signaling in articular chondrocytes leads to osteoarthritis-like phenotype in adult beta-catenin conditional activation mice
    • Jan;.
    • Zhu M, Tang D, Wu Q, Hao S, Chen M, Xie C, Rosier RN, O'Keefe RJ, Zuscik M, Chen D., Activation of beta-catenin signaling in articular chondrocytes leads to osteoarthritis-like phenotype in adult beta-catenin conditional activation mice. J Bone Miner Res. 2009 Jan; 24 (1): 12-21.
    • (2009) J Bone Miner Res. , vol.24 , Issue.1 , pp. 12-21
    • Zhu, M.1    Tang, D.2    Wu, Q.3    Hao, S.4    Chen, M.5    Xie, C.6    Rosier, R.N.7    O'Keefe, R.J.8    Zuscik, M.9    Chen, D.10
  • 35
    • 0033567213 scopus 로고    scopus 로고
    • Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation
    • Aug 15;.
    • St-Jacques B, Hammerschmidt M, McMahon AP., Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation. Genes Dev. 1999 Aug 15; 13 (16): 2072-86.
    • (1999) Genes Dev. , vol.13 , Issue.16 , pp. 2072-2086
    • St-Jacques, B.1    Hammerschmidt, M.2    McMahon, A.P.3
  • 36
    • 1842611651 scopus 로고    scopus 로고
    • Ihh signaling is directly required for the osteoblast lineage in the endochondral skeleton
    • Mar;.
    • Long F, Chung UI, Ohba S, McMahon J, Kronenberg HM, McMahon AP., Ihh signaling is directly required for the osteoblast lineage in the endochondral skeleton. Development. 2004 Mar; 131 (6): 1309-18.
    • (2004) Development. , vol.131 , Issue.6 , pp. 1309-1318
    • Long, F.1    Chung, U.I.2    Ohba, S.3    McMahon, J.4    Kronenberg, H.M.5    McMahon, A.P.6
  • 37
    • 46749111932 scopus 로고    scopus 로고
    • Indian hedgehog signals independently of PTHrP to promote chondrocyte hypertrophy
    • Jun;.
    • Mak KK, Kronenberg HM, Chuang PT, Mackem S, Yang Y., Indian hedgehog signals independently of PTHrP to promote chondrocyte hypertrophy. Development. 2008 Jun; 135 (11): 1947-56.
    • (2008) Development. , vol.135 , Issue.11 , pp. 1947-1956
    • Mak, K.K.1    Kronenberg, H.M.2    Chuang, P.T.3    MacKem, S.4    Yang, Y.5
  • 38
    • 66349117431 scopus 로고    scopus 로고
    • BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formation
    • Apr;.
    • Retting KN, Song B, Yoon BS, Lyons KM., BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formation. Development. 2009 Apr; 136 (7): 1093-104.
    • (2009) Development. , vol.136 , Issue.7 , pp. 1093-1104
    • Retting, K.N.1    Song, B.2    Yoon, B.S.3    Lyons, K.M.4
  • 39
    • 0034870121 scopus 로고    scopus 로고
    • Enzymes active in the areas undergoing cartilage resorption during the development of the secondary ossification center in the tibiae of rats aged 0-21 days: II. Two proteinases, gelatinase B and collagenase-3, are implicated in the lysis of collagen fibrils
    • Sep;.
    • Davoli MA, Lamplugh L, Beauchemin A, Chan K, Mordier S, Mort JS, Murphy G, Docherty AJ, Leblond CP, Lee ER., Enzymes active in the areas undergoing cartilage resorption during the development of the secondary ossification center in the tibiae of rats aged 0-21 days: II. Two proteinases, gelatinase B and collagenase-3, are implicated in the lysis of collagen fibrils. Dev Dyn. 2001 Sep; 222 (1): 71-88.
    • (2001) Dev Dyn. , vol.222 , Issue.1 , pp. 71-88
    • Davoli, M.A.1    Lamplugh, L.2    Beauchemin, A.3    Chan, K.4    Mordier, S.5    Mort, J.S.6    Murphy, G.7    Docherty, A.J.8    Leblond, C.P.9    Lee, E.R.10
  • 40
    • 71449101887 scopus 로고    scopus 로고
    • The Gli2 transcriptional activator is a crucial effector for Ihh signaling in osteoblast development and cartilage vascularization
    • Dec;.
    • Joeng KS, Long F., The Gli2 transcriptional activator is a crucial effector for Ihh signaling in osteoblast development and cartilage vascularization. Development. 2009 Dec; 136 (24): 4177-85.
    • (2009) Development. , vol.136 , Issue.24 , pp. 4177-4185
    • Joeng, K.S.1    Long, F.2
  • 41
    • 16844370419 scopus 로고    scopus 로고
    • Indian hedgehog synchronizes skeletal angiogenesis and perichondrial maturation with cartilage development
    • Mar;.
    • Colnot C, de la Fuente L, Huang S, Hu D, Lu C, St-Jacques B, Helms JA., Indian hedgehog synchronizes skeletal angiogenesis and perichondrial maturation with cartilage development. Development. 2005 Mar; 132 (5): 1057-67.
    • (2005) Development. , vol.132 , Issue.5 , pp. 1057-1067
    • Colnot, C.1    De La Fuente, L.2    Huang, S.3    Hu, D.4    Lu, C.5    St-Jacques, B.6    Helms, J.A.7
  • 42
    • 44449138137 scopus 로고    scopus 로고
    • Indian hedgehog promotes the migration of rat activated pancreatic stellate cells by increasing membrane type-1 matrix metalloproteinase on the plasma membrane
    • Jul;.
    • Shinozaki S, Ohnishi H, Hama K, Kita H, Yamamoto H, Osawa H, Sato K, Tamada K, Mashima H, Sugano K., Indian hedgehog promotes the migration of rat activated pancreatic stellate cells by increasing membrane type-1 matrix metalloproteinase on the plasma membrane. J Cell Physiol. 2008 Jul; 216 (1): 38-46.
    • (2008) J Cell Physiol. , vol.216 , Issue.1 , pp. 38-46
    • Shinozaki, S.1    Ohnishi, H.2    Hama, K.3    Kita, H.4    Yamamoto, H.5    Osawa, H.6    Sato, K.7    Tamada, K.8    Mashima, H.9    Sugano, K.10
  • 43
    • 33947098898 scopus 로고    scopus 로고
    • Wnt/BMP signal integration regulates the balance between proliferation and differentiation of neuroepithelial cells in the dorsal spinal cord
    • Apr 1;.
    • Ille F, Atanasoski S, Falk S, Ittner LM, Marki D, Buchmann-Moller S, Wurdak H, Suter U, Taketo MM, Sommer L., Wnt/BMP signal integration regulates the balance between proliferation and differentiation of neuroepithelial cells in the dorsal spinal cord. Dev Biol. 2007 Apr 1; 304 (1): 394-408.
    • (2007) Dev Biol. , vol.304 , Issue.1 , pp. 394-408
    • Ille, F.1    Atanasoski, S.2    Falk, S.3    Ittner, L.M.4    Marki, D.5    Buchmann-Moller, S.6    Wurdak, H.7    Suter, U.8    Taketo, M.M.9    Sommer, L.10
  • 44
    • 33646047408 scopus 로고    scopus 로고
    • Bone morphogenetic protein-2 modulates Wnt and frizzled expression and enhances the canonical pathway of Wnt signaling in normal keratinocytes
    • May;.
    • Yang L, Yamasaki K, Shirakata Y, Dai X, Tokumaru S, Yahata Y, Tohyama M, Hanakawa Y, Sayama K, Hashimoto K., Bone morphogenetic protein-2 modulates Wnt and frizzled expression and enhances the canonical pathway of Wnt signaling in normal keratinocytes. J Dermatol Sci. 2006 May; 42 (2): 111-9.
    • (2006) J Dermatol Sci. , vol.42 , Issue.2 , pp. 111-119
    • Yang, L.1    Yamasaki, K.2    Shirakata, Y.3    Dai, X.4    Tokumaru, S.5    Yahata, Y.6    Tohyama, M.7    Hanakawa, Y.8    Sayama, K.9    Hashimoto, K.10
  • 45
    • 22044454171 scopus 로고    scopus 로고
    • Bridging the BMP and Wnt pathways by PI3 kinase/Akt and 14-3-3zeta
    • Feb;.
    • Tian Q, He XC, Hood L, Li L., Bridging the BMP and Wnt pathways by PI3 kinase/Akt and 14-3-3zeta. Cell Cycle. 2005 Feb; 4 (2): 215-6.
    • (2005) Cell Cycle. , vol.4 , Issue.2 , pp. 215-216
    • Tian, Q.1    He, X.C.2    Hood, L.3    Li, L.4
  • 47
    • 77953381255 scopus 로고    scopus 로고
    • Wnt inhibitors Dkk1 and Sost are downstream targets of BMP signaling through the type IA receptor (BMPRIA) in osteoblasts
    • Feb;.
    • Kamiya N, Kobayashi T, Mochida Y, Yu PB, Yamauchi M, Kronenberg HM, Mishina Y., Wnt inhibitors Dkk1 and Sost are downstream targets of BMP signaling through the type IA receptor (BMPRIA) in osteoblasts. J Bone Miner Res. 2010 Feb; 25 (2): 200-10.
    • (2010) J Bone Miner Res. , vol.25 , Issue.2 , pp. 200-210
    • Kamiya, N.1    Kobayashi, T.2    Mochida, Y.3    Yu, P.B.4    Yamauchi, M.5    Kronenberg, H.M.6    Mishina, Y.7
  • 48
    • 0032970436 scopus 로고    scopus 로고
    • Localization of Smads, the TGF-beta family intracellular signaling components during endochondral ossification
    • Jul;.
    • Sakou T, Onishi T, Yamamoto T, Nagamine T, Sampath T, Ten Dijke P., Localization of Smads, the TGF-beta family intracellular signaling components during endochondral ossification. J Bone Miner Res. 1999 Jul; 14 (7): 1145-52.
    • (1999) J Bone Miner Res. , vol.14 , Issue.7 , pp. 1145-1152
    • Sakou, T.1    Onishi, T.2    Yamamoto, T.3    Nagamine, T.4    Sampath, T.5    Ten Dijke, P.6
  • 49
    • 0034522379 scopus 로고    scopus 로고
    • Smad2 and 3 mediate transforming growth factor-beta1-induced inhibition of chondrocyte maturation
    • Dec;.
    • Ferguson CM, Schwarz EM, Reynolds PR, Puzas JE, Rosier RN, O'Keefe RJ., Smad2 and 3 mediate transforming growth factor-beta1-induced inhibition of chondrocyte maturation. Endocrinology. 2000 Dec; 141 (12): 4728-35.
    • (2000) Endocrinology. , vol.141 , Issue.12 , pp. 4728-4735
    • Ferguson, C.M.1    Schwarz, E.M.2    Reynolds, P.R.3    Puzas, J.E.4    Rosier, R.N.5    O'Keefe, R.J.6
  • 51
    • 29144529005 scopus 로고    scopus 로고
    • BMP signaling stimulates cellular differentiation at multiple steps during cartilage development
    • Dec 13;.
    • Kobayashi T, Lyons KM, McMahon AP, Kronenberg HM., BMP signaling stimulates cellular differentiation at multiple steps during cartilage development. Proc Natl Acad Sci U S A. 2005 Dec 13; 102 (50): 18023-7.
    • (2005) Proc Natl Acad Sci U S A. , vol.102 , Issue.50 , pp. 18023-18027
    • Kobayashi, T.1    Lyons, K.M.2    McMahon, A.P.3    Kronenberg, H.M.4
  • 53
    • 33845971522 scopus 로고    scopus 로고
    • Genetic analysis of the roles of BMP2, BMP4, and BMP7 in limb patterning and skeletogenesis
    • Dec;.
    • Bandyopadhyay A, Tsuji K, Cox K, Harfe BD, Rosen V, Tabin CJ., Genetic analysis of the roles of BMP2, BMP4, and BMP7 in limb patterning and skeletogenesis. PLoS Genet. 2006 Dec; 2 (12): e216.
    • (2006) PLoS Genet. , vol.2 , Issue.12
    • Bandyopadhyay, A.1    Tsuji, K.2    Cox, K.3    Harfe, B.D.4    Rosen, V.5    Tabin, C.J.6
  • 54
    • 35848958601 scopus 로고    scopus 로고
    • Integration of signaling pathways regulating chondrocyte differentiation during endochondral bone formation
    • Dec;.
    • Adams SL, Cohen AJ, Lassova L., Integration of signaling pathways regulating chondrocyte differentiation during endochondral bone formation. J Cell Physiol. 2007 Dec; 213 (3): 635-41.
    • (2007) J Cell Physiol. , vol.213 , Issue.3 , pp. 635-641
    • Adams, S.L.1    Cohen, A.J.2    Lassova, L.3
  • 55
    • 37249015430 scopus 로고    scopus 로고
    • Multiplicity of BMP signaling in skeletal development
    • Nov.
    • Wu X, Shi W, Cao X., Multiplicity of BMP signaling in skeletal development. Ann N Y Acad Sci. 2007 Nov; 1116: 29-49.
    • (2007) Ann N y Acad Sci. , vol.1116 , pp. 29-49
    • Wu, X.1    Shi, W.2    Cao, X.3
  • 56
    • 34047250505 scopus 로고    scopus 로고
    • Wnt gene expression in the post-natal growth plate: Regulation with chondrocyte differentiation
    • May;.
    • Andrade AC, Nilsson O, Barnes KM, Baron J., Wnt gene expression in the post-natal growth plate: regulation with chondrocyte differentiation. Bone. 2007 May; 40 (5): 1361-9.
    • (2007) Bone. , vol.40 , Issue.5 , pp. 1361-1369
    • Andrade, A.C.1    Nilsson, O.2    Barnes, K.M.3    Baron, J.4
  • 58
    • 35648931969 scopus 로고    scopus 로고
    • Transforming growth factor-beta and Wnt signals regulate chondrocyte differentiation through Twist1 in a stage-specific manner
    • Nov;.
    • Dong YF, Soung do Y, Chang Y, Enomoto-Iwamoto M, Paris M, O'Keefe RJ, Schwarz EM, Drissi H., Transforming growth factor-beta and Wnt signals regulate chondrocyte differentiation through Twist1 in a stage-specific manner. Mol Endocrinol. 2007 Nov; 21 (11): 2805-20.
    • (2007) Mol Endocrinol. , vol.21 , Issue.11 , pp. 2805-2820
    • Dong, Y.F.1    Soung Do, Y.2    Chang, Y.3    Enomoto-Iwamoto, M.4    Paris, M.5    O'Keefe, R.J.6    Schwarz, E.M.7    Drissi, H.8
  • 59
    • 36549008617 scopus 로고    scopus 로고
    • Skeletal development-Wnts are in control
    • Oct 31;.
    • Hartmann C., Skeletal development-Wnts are in control. Mol Cells. 2007 Oct 31; 24 (2): 177-84.
    • (2007) Mol Cells. , vol.24 , Issue.2 , pp. 177-184
    • Hartmann, C.1
  • 60
    • 42949117323 scopus 로고    scopus 로고
    • Roles of Wnt signalling in bone growth, remodelling, skeletal disorders and fracture repair
    • Jun;.
    • Macsai CE, Foster BK, Xian CJ., Roles of Wnt signalling in bone growth, remodelling, skeletal disorders and fracture repair. J Cell Physiol. 2008 Jun; 215 (3): 578-87.
    • (2008) J Cell Physiol. , vol.215 , Issue.3 , pp. 578-587
    • MacSai, C.E.1    Foster, B.K.2    Xian, C.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.