Gene silencing activity of siRNA molecules containing phosphorodithioate substitutions

ACS Chemical Biology

Volumn 7, Issue 7, 2012, Pages 1214-1220

  Yang, Xianbin ^a   Sierant, Malgorzata ^b   Janicka, Magdalena ^b   Peczek, Lukasz ^b   Martinez, Carlos ^c   Hassell, Tom ^c   Li, Na ^a   Li, Xin ^a   Wang, Tianzhi ^d   Nawrot, Barbara ^b  

^a AM Biotechnologies   (United States)

^b CENTRE OF MOLECULAR AND MACROMOLECULAR STUDIES   (Poland)

^c Sigma Life Science   (United States)

^d University of Texas Medical Branch School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MONOMER; OXYGEN; PHOSPHOROTHIOIC ACID DERIVATIVE; RIBONUCLEOSIDE 3' YL S [BETA (BENZOYLMERCAPTO) ETHYL]PYRROLIDINO THIOPHOSPHORAMIDITE; SMALL INTERFERING RNA; SULFUR; UNCLASSIFIED DRUG;

ARTICLE; ASSAY; CHEMICAL MODIFICATION; CHEMICAL STRUCTURE; CIRCULAR DICHROISM; CONTROLLED STUDY; DUAL FLUORESCENCE ASSAY; GENE SILENCING; PHOSPHORYLATION; PRIORITY JOURNAL; RNA PURIFICATION; RNA SYNTHESIS; SUBSTITUTION REACTION;

GENE SILENCING; HELA CELLS; HUMANS; PHOSPHATES; RNA, SMALL INTERFERING;

EID: 84864136092     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb300078e     Document Type: Article

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