Lysophosphatidic acid activates lipogenic pathways and de novo lipid synthesis in ovarian cancer cells

Journal of Biological Chemistry

Volumn 287, Issue 30, 2012, Pages 24990-25000

  Mukherjee, Abir ^a   Wu, Jinhua ^a   Barbour, Suzanne ^a   Fang, Xianjun ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL-COA CARBOXYLASE; AMP-ACTIVATED PROTEIN KINASE; ANTI-CANCER THERAPIES; ANTITUMOR EFFECT; CANCER CELLS; EPITHELIAL CELLS; FATTY ACID SYNTHASE; LIPID SYNTHESIS; LIPOGENESIS; LIPOGENIC ENZYMES; LYSOPHOSPHATIDIC ACID; MALIGNANT CELLS; MOLECULAR CHANGES; MOUSE MODELS; OVARIAN CANCER CELLS; OVARIAN CANCERS; OVER-EXPRESSION; PHARMACOLOGICAL INHIBITORS; SIGNALING CASCADES; STEROL REGULATORY ELEMENT-BINDING PROTEINS; STEROL REGULATORY ELEMENTS; TUMOR CELLS;

ALCOHOLS; CELL CULTURE; CELL PROLIFERATION; DISEASES; PHOSPHOLIPIDS; PROTEINS;

CELLS;

ACETYL COENZYME A CARBOXYLASE; FATTY ACID SYNTHASE; GUANINE NUCLEOTIDE BINDING PROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; LYSOPHOSPHATIDIC ACID; LYSOPHOSPHATIDIC ACID RECEPTOR; RHO FACTOR; STEROL REGULATORY ELEMENT BINDING PROTEIN;

ARTICLE; CANCER CELL CULTURE; CELL IMMORTALIZATION; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CORRELATIONAL STUDY; ENZYME INHIBITION; EPITHELIUM CELL; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; LIPOGENESIS; OVARY CANCER; PHENOTYPE; PHOSPHOLIPID METABOLISM; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TUMOR MICROENVIRONMENT;

ANIMALS; CELL LINE, TUMOR; FATTY ACID SYNTHETASE COMPLEX; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GTP-BINDING PROTEIN ALPHA SUBUNITS, G12-G13; HUMANS; LIPOGENESIS; LYSOPHOSPHOLIPIDS; MICE; NEOPLASM PROTEINS; OVARIAN NEOPLASMS; RECEPTORS, LYSOPHOSPHATIDIC ACID; REGULATORY ELEMENTS, TRANSCRIPTIONAL; SIGNAL TRANSDUCTION;

EID: 84864078672     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.340083     Document Type: Article

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