Propagation of RML prions in mice expressing PrP devoid of GPI anchor leads to formation of a novel, stable prion strain

PLoS Pathogens

Volumn 8, Issue 6, 2012, Pages

  Mahal, Sukhvir Paul ^a   Jablonski, Joseph ^a   Suponitsky Kroyter, Irena ^a,c   Oelschlegel, Anja Maria ^a   Herva, Maria Eugenia ^a,d   Oldstone, Michael ^b   Weissmann, Charles ^a  

^a Scripps Florida ^*  (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c OPKO Health Inc   (United States)

^d The Center for Brain Repair   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOSYLPHOSPHATIDYLINOSITOL; PRION PROTEIN; GPAA1 PROTEIN, MOUSE; MEMBRANE PROTEIN;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; MOUSE; NONHUMAN; PRION; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN PROCESSING; RML PRION; SFL PRION; VIRAL TROPISM; VIRUS REPLICATION; VIRUS STRAIN; ANIMAL; C57BL MOUSE; CHEMISTRY; DISEASE TRANSMISSION; ENZYME LINKED IMMUNOSORBENT ASSAY; METABOLISM; SCRAPIE; TRANSGENIC MOUSE; WESTERN BLOTTING;

ANIMALIA; MUS;

ANIMALS; BLOTTING, WESTERN; ENZYME-LINKED IMMUNOSORBENT ASSAY; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PROTEIN CONFORMATION; PRPC PROTEINS; PRPSC PROTEINS; SCRAPIE;

EID: 84864064734     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002746     Document Type: Article

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