Prion inhibition with multivalent PrPSc binding compounds

Biomaterials

Volumn 33, Issue 28, 2012, Pages 6808-6822

  Mays, Charles E ^a   Joy, Shaon ^b   Li, Lei ^b   Yu, Linghui ^b   Genovesi, Sacha ^a   West, Frederick G ^b   Westaway, David ^a,b  

^a UNIVERSITY OF ALBERTA   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Acridine; Chloroquinoline; Congo red; Prion; Quinacrine; Therapy

Indexed keywords

ACRIDINE; CHLOROQUINOLINE; CONGO RED; PRION; QUINACRINE; THERAPY;

AZO DYES;

SCAFFOLDS (BIOLOGY);

CONGO RED; MEPACRINE; PRION PROTEIN; QUINOLINE DERIVATIVE; TETRAPHENYLPORPHYRIN;

ARTICLE; CELL CULTURE; CONTROLLED STUDY; DRUG ACTIVITY; HUMAN; HUMAN CELL; IC 50; PRION DISEASE; PRIORITY JOURNAL;

ANIMALS; CELL LINE, TUMOR; CHLOROQUINOLINOLS; CONGO RED; HUMANS; INHIBITORY CONCENTRATION 50; MICE; PORPHYRINS; PRION DISEASES; PRIONS; PRPSC PROTEINS; QUINACRINE; STRUCTURE-ACTIVITY RELATIONSHIP; TRICARBOXYLIC ACIDS;

EID: 84864019537     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.06.004     Document Type: Article

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