-
1
-
-
79953156769
-
Mitotic spindle misorientation in cancer - out of alignment and into the fire
-
Pease JC, Tirnauer JS, (2011) Mitotic spindle misorientation in cancer- out of alignment and into the fire. Journal of Cell Science 124: 1007-1016.
-
(2011)
Journal of Cell Science
, vol.124
, pp. 1007-1016
-
-
Pease, J.C.1
Tirnauer, J.S.2
-
3
-
-
64049088018
-
Spindle orientation during asymmetric cell division
-
Siller KH, Doe CQ, (2009) Spindle orientation during asymmetric cell division. Nature Cell Biology 11: 365-374.
-
(2009)
Nature Cell Biology
, vol.11
, pp. 365-374
-
-
Siller, K.H.1
Doe, C.Q.2
-
4
-
-
79953293527
-
Par6B and Atypical PKC Regulate Mitotic Spindle Orientation during Epithelial Morphogenesis
-
Durgan J, Kaji N, Jin D, Hall A, (2011) Par6B and Atypical PKC Regulate Mitotic Spindle Orientation during Epithelial Morphogenesis. The Journal of Biological Chemistry 286: 12461-12474.
-
(2011)
The Journal of Biological Chemistry
, vol.286
, pp. 12461-12474
-
-
Durgan, J.1
Kaji, N.2
Jin, D.3
Hall, A.4
-
5
-
-
78049255724
-
Par3 controls epithelial spindle orientation by aPKC-mediated phosphorylation of apical Pins
-
Hao Y, Du Q, Chen X, Zheng Z, Balsbaugh JL, et al. (2010) Par3 controls epithelial spindle orientation by aPKC-mediated phosphorylation of apical Pins. Current Biology 20: 1809-1818.
-
(2010)
Current Biology
, vol.20
, pp. 1809-1818
-
-
Hao, Y.1
Du, Q.2
Chen, X.3
Zheng, Z.4
Balsbaugh, J.L.5
-
7
-
-
77951174042
-
LGN regulates mitotic spindle orientation during epithelial morphogenesis
-
Zheng Z, Zhu H, Wan Q, Liu J, Xiao Z, et al. (2010) LGN regulates mitotic spindle orientation during epithelial morphogenesis. Journal of Cell Biology 189: 275-288.
-
(2010)
Journal of Cell Biology
, vol.189
, pp. 275-288
-
-
Zheng, Z.1
Zhu, H.2
Wan, Q.3
Liu, J.4
Xiao, Z.5
-
8
-
-
67649227820
-
Spindle misorientation in tumors from APCmin/+ mice
-
Fleming ES, Temchin M, Wu Q, Maggio-Price L, Tirnauer JS, (2009) Spindle misorientation in tumors from APCmin/+ mice. Molecular Carcinogenesis 48: 592-598.
-
(2009)
Molecular Carcinogenesis
, vol.48
, pp. 592-598
-
-
Fleming, E.S.1
Temchin, M.2
Wu, Q.3
Maggio-Price, L.4
Tirnauer, J.S.5
-
9
-
-
75349094518
-
Spindle orientation bias in gut epithelial stem cell compartments is lost in precancerous tissue
-
Quyn AJ, Appleton PL, Carey FA, Steele RJ, Barker N, et al. (2010) Spindle orientation bias in gut epithelial stem cell compartments is lost in precancerous tissue. Cell Stem Cell 6: 175-181.
-
(2010)
Cell Stem Cell
, vol.6
, pp. 175-181
-
-
Quyn, A.J.1
Appleton, P.L.2
Carey, F.A.3
Steele, R.J.4
Barker, N.5
-
10
-
-
68249112645
-
VHL loss causes spindle misorientation and chromosome instability
-
Thoma CR, Toso A, Gutbrodt KL, Reggi SP, Frew IJ, et al. (2009) VHL loss causes spindle misorientation and chromosome instability. Nature Cell Biology epub ahead of print.
-
(2009)
Nature Cell Biology Epub Ahead of Print
-
-
Thoma, C.R.1
Toso, A.2
Gutbrodt, K.L.3
Reggi, S.P.4
Frew, I.J.5
-
11
-
-
69949106214
-
Cadherin Adhesion Receptors Orient the Mitotic Spindle during Symmetric Cell Division in Mammalian Epithelia
-
den Elzen N, Buttery CV, Maddugoda MP, Ren G, Yap AS, (2009) Cadherin Adhesion Receptors Orient the Mitotic Spindle during Symmetric Cell Division in Mammalian Epithelia. Molecular Biology of the Cell 20: 3740-3750.
-
(2009)
Molecular Biology of the Cell
, vol.20
, pp. 3740-3750
-
-
den Elzen, N.1
Buttery, C.V.2
Maddugoda, M.P.3
Ren, G.4
Yap, A.S.5
-
12
-
-
0032495530
-
A serine/threonine kinase gene defective in Peutz-Jeghers syndrome
-
Hemminki A, Markie D, Tomlinson I, Avizienyte E, Roth S, et al. (1998) A serine/threonine kinase gene defective in Peutz-Jeghers syndrome. Nature 391: 184-187.
-
(1998)
Nature
, vol.391
, pp. 184-187
-
-
Hemminki, A.1
Markie, D.2
Tomlinson, I.3
Avizienyte, E.4
Roth, S.5
-
13
-
-
0032471851
-
Loss of LKB1 kinase activity in Peutz-Jeghers syndrome, and evidence for allelic and locus heterogeneity
-
Mehenni H, Gehrig C, Nezu J, Oku A, Shimane M, et al. (1998) Loss of LKB1 kinase activity in Peutz-Jeghers syndrome, and evidence for allelic and locus heterogeneity. American Journal of Human Genetics 63: 1641-1650.
-
(1998)
American Journal of Human Genetics
, vol.63
, pp. 1641-1650
-
-
Mehenni, H.1
Gehrig, C.2
Nezu, J.3
Oku, A.4
Shimane, M.5
-
14
-
-
77953230425
-
High cancer risk in Peutz-Jeghers syndrome: a systematic review and surveillance recommendations
-
van Lier MG, Wagner A, Mathus-Vliegen EM, Kuipers EJ, Steyerberg EW, et al. (2010) High cancer risk in Peutz-Jeghers syndrome: a systematic review and surveillance recommendations. American Journal of Gastroenterology 105: 1258-1264.
-
(2010)
American Journal of Gastroenterology
, vol.105
, pp. 1258-1264
-
-
van Lier, M.G.1
Wagner, A.2
Mathus-Vliegen, E.M.3
Kuipers, E.J.4
Steyerberg, E.W.5
-
15
-
-
67650898228
-
LKB1 and AMPK Family Signaling: The Intimate Link Between Cell Polarity and Energy Metabolism
-
Jansen M, Klooster JPT, Offerhaus GJ, Clevers H, (2009) LKB1 and AMPK Family Signaling: The Intimate Link Between Cell Polarity and Energy Metabolism. Physiology Reveiws 89: 777-798.
-
(2009)
Physiology Reveiws
, vol.89
, pp. 777-798
-
-
Jansen, M.1
Klooster, J.P.T.2
Offerhaus, G.J.3
Clevers, H.4
-
16
-
-
0034464147
-
Very High Risk of Cancer in Familial Peutz-Jeghers Syndrome
-
Giardiello FM, Brensinger JD, Tersmette AC, Goodman SN, Petersen GM, et al. (2000) Very High Risk of Cancer in Familial Peutz-Jeghers Syndrome. Gastroenterology 119: 1447-1453.
-
(2000)
Gastroenterology
, vol.119
, pp. 1447-1453
-
-
Giardiello, F.M.1
Brensinger, J.D.2
Tersmette, A.C.3
Goodman, S.N.4
Petersen, G.M.5
-
17
-
-
0032906537
-
Mutations and impaired function of LKB1 in familial and non-familial Peutz-Jeghers syndrome and a sporadic testicular cancer
-
Ylikorkala A, Avizienyte E, Tomlinson IP, Tiainen M, Roth S, et al. (1999) Mutations and impaired function of LKB1 in familial and non-familial Peutz-Jeghers syndrome and a sporadic testicular cancer. Human Molecular Genetics 8: 45-51.
-
(1999)
Human Molecular Genetics
, vol.8
, pp. 45-51
-
-
Ylikorkala, A.1
Avizienyte, E.2
Tomlinson, I.P.3
Tiainen, M.4
Roth, S.5
-
18
-
-
2542590883
-
Novel and natural knockout lung cancer cell lines for the LKB1/STK11 tumor suppressor gene
-
Carretero J, Medina PP, Pio R, Montuenga LM, Sanchez-Cespedes M, (2004) Novel and natural knockout lung cancer cell lines for the LKB1/STK11 tumor suppressor gene. Oncogene 23: 4037-4040.
-
(2004)
Oncogene
, vol.23
, pp. 4037-4040
-
-
Carretero, J.1
Medina, P.P.2
Pio, R.3
Montuenga, L.M.4
Sanchez-Cespedes, M.5
-
19
-
-
25444524851
-
Mutations in the human LKB1/STK11 gene
-
Launonen V, (2005) Mutations in the human LKB1/STK11 gene. Human Mutation 26: 291-297.
-
(2005)
Human Mutation
, vol.26
, pp. 291-297
-
-
Launonen, V.1
-
20
-
-
0036645286
-
Inactivation of LKB1/STK11 Is a Common Event in Adenocarcinomas of the Lung
-
Sanchez-Cespedes M, Parrella P, Esteller M, Nomoto S, Trink B, et al. (2002) Inactivation of LKB1/STK11 Is a Common Event in Adenocarcinomas of the Lung. Cancer Research 62: 3659-3662.
-
(2002)
Cancer Research
, vol.62
, pp. 3659-3662
-
-
Sanchez-Cespedes, M.1
Parrella, P.2
Esteller, M.3
Nomoto, S.4
Trink, B.5
-
21
-
-
0032984141
-
Germline and somatic mutations of the STK11/LKB1 Peutz-Jeghers gene in pancreatic and biliary cancers
-
Su GH, Hruban RH, Bansal RK, Bova GS, Tang DJ, et al. (1999) Germline and somatic mutations of the STK11/LKB1 Peutz-Jeghers gene in pancreatic and biliary cancers. American Journal of Pathology 154: 1835-1840.
-
(1999)
American Journal of Pathology
, vol.154
, pp. 1835-1840
-
-
Su, G.H.1
Hruban, R.H.2
Bansal, R.K.3
Bova, G.S.4
Tang, D.J.5
-
23
-
-
33845411885
-
The LKB1 tumor suppressor kinase in human disease
-
Katajisto P, Vallenius T, Vaahtomeri K, Ekman N, Udd L, et al. (2007) The LKB1 tumor suppressor kinase in human disease. Biochimica et Biophysica Acta 1775: 63-75.
-
(2007)
Biochimica Et Biophysica Acta
, vol.1775
, pp. 63-75
-
-
Katajisto, P.1
Vallenius, T.2
Vaahtomeri, K.3
Ekman, N.4
Udd, L.5
-
24
-
-
0345107247
-
Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade
-
Hawley SA, Boudeau J, Reid JL, Mustard KJ, Udd L, et al. (2003) Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade. Journal of BIology 2: 28.
-
(2003)
Journal of BIology
, vol.2
, pp. 28
-
-
Hawley, S.A.1
Boudeau, J.2
Reid, J.L.3
Mustard, K.J.4
Udd, L.5
-
25
-
-
12144287284
-
LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1
-
Lizcano JM, Gorannson O, Toth R, Deak M, Morrice NA, et al. (2004) LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1. EMBO Journal 23: 833-843.
-
(2004)
EMBO Journal
, vol.23
, pp. 833-843
-
-
Lizcano, J.M.1
Gorannson, O.2
Toth, R.3
Deak, M.4
Morrice, N.A.5
-
26
-
-
77949462458
-
AMPK as a metabolic tumor suppressor: control of metabolism and cell growth
-
Luo Z, Zang M, Guo W, (2010) AMPK as a metabolic tumor suppressor: control of metabolism and cell growth. Future Oncology 6: 457-470.
-
(2010)
Future Oncology
, vol.6
, pp. 457-470
-
-
Luo, Z.1
Zang, M.2
Guo, W.3
-
27
-
-
79953248896
-
Molecular mechanisms of tumor suppression by LKB1
-
Vaahtomeri K, Makela TP, (2011) Molecular mechanisms of tumor suppression by LKB1. FEBS Letters 585: 944-951.
-
(2011)
FEBS Letters
, vol.585
, pp. 944-951
-
-
Vaahtomeri, K.1
Makela, T.P.2
-
28
-
-
77952116629
-
Metformin in cancer therapy: a new perspective for an old antidiabetic drug?
-
Ben Sahra I, Le Marchand-Brustel Y, Tanti JF, Bost F, (2010) Metformin in cancer therapy: a new perspective for an old antidiabetic drug? Molecular Cancer Therapeutics 9: 1092-1099.
-
(2010)
Molecular Cancer Therapeutics
, vol.9
, pp. 1092-1099
-
-
Ben Sahra, I.1
Le Marchand-Brustel, Y.2
Tanti, J.F.3
Bost, F.4
-
29
-
-
33745213627
-
AMPK and cell proliferation-AMPK as a therapeutic target for atherosclerosis and cancer
-
Motoshima H, Goldstein BJ, Igata M, Araki E, (2006) AMPK and cell proliferation-AMPK as a therapeutic target for atherosclerosis and cancer. Journal of Physiology 574: 63-71.
-
(2006)
Journal of Physiology
, vol.574
, pp. 63-71
-
-
Motoshima, H.1
Goldstein, B.J.2
Igata, M.3
Araki, E.4
-
30
-
-
2942729619
-
LBK1 tumor suppressor protein: PARtaker in cell polarity
-
Baas AF, Smit L, Clevers H, (2004) LBK1 tumor suppressor protein: PARtaker in cell polarity. Trends in Cell Biology 14: 312-319.
-
(2004)
Trends in Cell Biology
, vol.14
, pp. 312-319
-
-
Baas, A.F.1
Smit, L.2
Clevers, H.3
-
31
-
-
41149117383
-
LKB1 and AMPK in cell polarity and division
-
Williams T, Brenman JE, (2008) LKB1 and AMPK in cell polarity and division. Trends in Cell Biology 18: 193-198.
-
(2008)
Trends in Cell Biology
, vol.18
, pp. 193-198
-
-
Williams, T.1
Brenman, J.E.2
-
32
-
-
0034090975
-
The C. elegans par-4 gene encodes a putative serine-threonine kinase required for establishing embryonic asymmetry
-
Watts JL, Morton DG, Bestman J, Kemphues KJ, (2000) The C. elegans par-4 gene encodes a putative serine-threonine kinase required for establishing embryonic asymmetry. Development 127: 1467-1475.
-
(2000)
Development
, vol.127
, pp. 1467-1475
-
-
Watts, J.L.1
Morton, D.G.2
Bestman, J.3
Kemphues, K.J.4
-
33
-
-
0026773728
-
par-4, a gene required for cytoplasmic localization and determination of specific cell types in Caenorhabditis elegans embryogenesis
-
Morton DG, Roos JM, Kemphues KJ, (1992) par-4, a gene required for cytoplasmic localization and determination of specific cell types in Caenorhabditis elegans embryogenesis. Genetics 130: 771-790.
-
(1992)
Genetics
, vol.130
, pp. 771-790
-
-
Morton, D.G.1
Roos, J.M.2
Kemphues, K.J.3
-
34
-
-
0037461735
-
A role for Drosophila LKB1 in anterior-posterior axis formation and epithelial polarity
-
Martin SG, St Johnston D, (2003) A role for Drosophila LKB1 in anterior-posterior axis formation and epithelial polarity. Nature 421: 379-384.
-
(2003)
Nature
, vol.421
, pp. 379-384
-
-
Martin, S.G.1
St Johnston, D.2
-
35
-
-
0037089467
-
Gastrointestinal hamartomatous polyposis in Lkb1 heterozygous knockout mice
-
Miyoshi H, Nakau M, Ishikawa TO, Seldin MF, Oshima M, et al. (2002) Gastrointestinal hamartomatous polyposis in Lkb1 heterozygous knockout mice. Cancer Research 62: 2261-2266.
-
(2002)
Cancer Research
, vol.62
, pp. 2261-2266
-
-
Miyoshi, H.1
Nakau, M.2
Ishikawa, T.O.3
Seldin, M.F.4
Oshima, M.5
-
36
-
-
39749194712
-
Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms
-
Hezel AF, Gurumurthy S, Granot Z, Swisa A, Chu GC, et al. (2008) Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms. Molecular and Cellular Biology 28: 2414-2425.
-
(2008)
Molecular and Cellular Biology
, vol.28
, pp. 2414-2425
-
-
Hezel, A.F.1
Gurumurthy, S.2
Granot, Z.3
Swisa, A.4
Chu, G.C.5
-
37
-
-
70350436136
-
Conditional deletion of the Lkb1 gene in the mouse mammary gland induces tumour formation
-
McCarthy A, Lord CJ, Savage K, Grigoriadis A, Smith DP, et al. (2009) Conditional deletion of the Lkb1 gene in the mouse mammary gland induces tumour formation. Journal of Pathology: Epub ahead of print.
-
(2009)
Journal of Pathology: Epub Ahead of Print
-
-
McCarthy, A.1
Lord, C.J.2
Savage, K.3
Grigoriadis, A.4
Smith, D.P.5
-
38
-
-
0037102428
-
Hepatocellular carcinoma caused by loss of heterozygosity in Lkb1 gene knockout mice
-
Nakau M, Miyoshi H, Seldin MF, Imamura M, Oshima M, et al. (2002) Hepatocellular carcinoma caused by loss of heterozygosity in Lkb1 gene knockout mice. Cancer Research 62: 4549-4553.
-
(2002)
Cancer Research
, vol.62
, pp. 4549-4553
-
-
Nakau, M.1
Miyoshi, H.2
Seldin, M.F.3
Imamura, M.4
Oshima, M.5
-
39
-
-
0035903028
-
Vascular abnormalities and deregulation of VEGF in Lkb1-deficient mice
-
Ylikorkala A, Rossi DJ, Korsisaari N, Luukko K, Alitalo K, et al. (2001) Vascular abnormalities and deregulation of VEGF in Lkb1-deficient mice. Science 293: 1323-1326.
-
(2001)
Science
, vol.293
, pp. 1323-1326
-
-
Ylikorkala, A.1
Rossi, D.J.2
Korsisaari, N.3
Luukko, K.4
Alitalo, K.5
-
40
-
-
1542777034
-
Complete Polarization of Single Intestinal Epithelial Cells upon Activation of LKB1 by STRAD
-
Baas AF, Kuipers J, van der Wel NN, Batlle E, Koerten HK, et al. (2004) Complete Polarization of Single Intestinal Epithelial Cells upon Activation of LKB1 by STRAD. Cell 116: 457-466.
-
(2004)
Cell
, vol.116
, pp. 457-466
-
-
Baas, A.F.1
Kuipers, J.2
van der Wel, N.N.3
Batlle, E.4
Koerten, H.K.5
-
41
-
-
77957735280
-
LKB1 tumor suppressor protein regulates actin filament assembly through Rho and its exchange factor Dbl independently of kinase activity
-
Xu X, Omelchenko T, Hall A, (2010) LKB1 tumor suppressor protein regulates actin filament assembly through Rho and its exchange factor Dbl independently of kinase activity. BMC Cell Biology 11: 77.
-
(2010)
BMC Cell Biology
, vol.11
, pp. 77
-
-
Xu, X.1
Omelchenko, T.2
Hall, A.3
-
42
-
-
34548179000
-
Suppression of Tubulin Polymerization by the LKB1-Microtubule-associated Protein/Microtubule Affinity-regulating Kinase Signaling
-
Kojima Y, Miyoshi H, Clevers HC, Oshima M, Aoki M, et al. (2007) Suppression of Tubulin Polymerization by the LKB1-Microtubule-associated Protein/Microtubule Affinity-regulating Kinase Signaling. Journal of Biological Chemistry 282: 23532-23540.
-
(2007)
Journal of Biological Chemistry
, vol.282
, pp. 23532-23540
-
-
Kojima, Y.1
Miyoshi, H.2
Clevers, H.C.3
Oshima, M.4
Aoki, M.5
-
43
-
-
84856820958
-
LKB1 Destabilizes Microtubules in Myoblasts and Contributes to Myoblast Differentiation
-
Mian I, Pierre-Louis WS, Dole N, Gilberti RM, Dodge-Kafka K, et al. (2012) LKB1 Destabilizes Microtubules in Myoblasts and Contributes to Myoblast Differentiation. PLoS One 7: e31583.
-
(2012)
PLoS One
, vol.7
-
-
Mian, I.1
Pierre-Louis, W.S.2
Dole, N.3
Gilberti, R.M.4
Dodge-Kafka, K.5
-
44
-
-
0042090214
-
Regulation of the Wnt signalling component PAR1A by the Peutz-Jeghers syndrome kinase LKB1
-
Spicer J, Rayter S, Young N, Elliott R, Ashworth A, et al. (2003) Regulation of the Wnt signalling component PAR1A by the Peutz-Jeghers syndrome kinase LKB1. Oncogene 22: 4752-4756.
-
(2003)
Oncogene
, vol.22
, pp. 4752-4756
-
-
Spicer, J.1
Rayter, S.2
Young, N.3
Elliott, R.4
Ashworth, A.5
-
46
-
-
34248185949
-
LKB1 and AMPK maintain epithelial cell polarity under energetic stress
-
Mirouse V, Swick LL, Kazgan N, St Johnston D, Brenman JE, (2007) LKB1 and AMPK maintain epithelial cell polarity under energetic stress. Journal of Cell Biology 177: 387-392.
-
(2007)
Journal of Cell Biology
, vol.177
, pp. 387-392
-
-
Mirouse, V.1
Swick, L.L.2
Kazgan, N.3
St Johnston, D.4
Brenman, J.E.5
-
47
-
-
1542618348
-
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress
-
Shaw RJ, Kosmatka M, Bardeesy N, Hurley RL, Witters LA, et al. (2004) The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress. Proceedings of the National Academy of Sciences U S A 101: 3329-3335.
-
(2004)
Proceedings of the National Academy of Sciences U S A
, vol.101
, pp. 3329-3335
-
-
Shaw, R.J.1
Kosmatka, M.2
Bardeesy, N.3
Hurley, R.L.4
Witters, L.A.5
-
48
-
-
72949115493
-
Structure of the LKB1-STRAD-MO25 complex reveals an allosteric mechanism of kinase activation
-
Zeqiraj E, Filippi BM, Deak M, Alessi DR, van Aalten DM, (2009) Structure of the LKB1-STRAD-MO25 complex reveals an allosteric mechanism of kinase activation. Science 326: 1707-1711.
-
(2009)
Science
, vol.326
, pp. 1707-1711
-
-
Zeqiraj, E.1
Filippi, B.M.2
Deak, M.3
Alessi, D.R.4
van Aalten, D.M.5
-
49
-
-
77953121697
-
AMPK controls the speed of microtubule polymerization and directional cell migration through CLIP-170 phosphorylation
-
Nakano A, Kato H, Watanabe T, Min KD, Yamazaki S, et al. (2010) AMPK controls the speed of microtubule polymerization and directional cell migration through CLIP-170 phosphorylation. Nature Cell Biology 12: 583-590.
-
(2010)
Nature Cell Biology
, vol.12
, pp. 583-590
-
-
Nakano, A.1
Kato, H.2
Watanabe, T.3
Min, K.D.4
Yamazaki, S.5
-
50
-
-
78649811793
-
Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells
-
Nakada D, Saunders TL, Morrison SJ, (2010) Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells. Nature 468: 653-658.
-
(2010)
Nature
, vol.468
, pp. 653-658
-
-
Nakada, D.1
Saunders, T.L.2
Morrison, S.J.3
-
51
-
-
34250844968
-
The Drosophila Lkb1 kinase is required for spindle formation and asymmetric neuroblast division
-
Bonaccorsi S, Mottier V, Giansanti MG, Bolkan BJ, Williams B, et al. (2007) The Drosophila Lkb1 kinase is required for spindle formation and asymmetric neuroblast division. Development 134: 2183-2193.
-
(2007)
Development
, vol.134
, pp. 2183-2193
-
-
Bonaccorsi, S.1
Mottier, V.2
Giansanti, M.G.3
Bolkan, B.J.4
Williams, B.5
-
52
-
-
36549040859
-
The selectivity of protein kinase inhibitors: a further update
-
Bain J, Plater L, Elliott M, Shpiro N, Hastie CJ, et al. (2007) The selectivity of protein kinase inhibitors: a further update. Biochem Journal 408: 297-315.
-
(2007)
Biochem Journal
, vol.408
, pp. 297-315
-
-
Bain, J.1
Plater, L.2
Elliott, M.3
Shpiro, N.4
Hastie, C.J.5
-
53
-
-
29244474612
-
Mutation of Lkb1 and p53 genes exert a cooperative effect on tumorigenesis
-
Wei C, Amos CI, Stephens LC, Campos I, Deng JM, et al. (2005) Mutation of Lkb1 and p53 genes exert a cooperative effect on tumorigenesis. Cancer Research 65: 11297-11303.
-
(2005)
Cancer Research
, vol.65
, pp. 11297-11303
-
-
Wei, C.1
Amos, C.I.2
Stephens, L.C.3
Campos, I.4
Deng, J.M.5
-
54
-
-
0032893658
-
Allelic imbalance at the LKB1 (STK11) locus in tumours from patients with Peutz-Jeghers' syndrome provides evidence for a hamartoma-(adenoma)-carcinoma sequence
-
Wang ZJ, Ellis I, Zauber P, Iwama T, Marchese C, et al. (1999) Allelic imbalance at the LKB1 (STK11) locus in tumours from patients with Peutz-Jeghers' syndrome provides evidence for a hamartoma-(adenoma)-carcinoma sequence. Journal of Pathology 188: 9-13.
-
(1999)
Journal of Pathology
, vol.188
, pp. 9-13
-
-
Wang, Z.J.1
Ellis, I.2
Zauber, P.3
Iwama, T.4
Marchese, C.5
-
55
-
-
0037068461
-
Loss of the Lkb2 tumour suppressor provokes intestinal polyposis but resistance to transformation
-
Bardeesy N, Sinha M, Hezel AF, Signoretti S, Hathaway NA, et al. (2002) Loss of the Lkb2 tumour suppressor provokes intestinal polyposis but resistance to transformation. Nature 419: 162-167.
-
(2002)
Nature
, vol.419
, pp. 162-167
-
-
Bardeesy, N.1
Sinha, M.2
Hezel, A.F.3
Signoretti, S.4
Hathaway, N.A.5
-
56
-
-
79953129026
-
Mitotic Spindle Imaging Reveals Planar Cell Polarity in the Mammalian Small Intestine
-
Fleming ES, Zajac M, Moschenross DM, Montrose DC, Rosenberg DW, et al. (2007) Mitotic Spindle Imaging Reveals Planar Cell Polarity in the Mammalian Small Intestine. Journal of Histochemistry and Cytochemistry 48: 592-598.
-
(2007)
Journal of Histochemistry and Cytochemistry
, vol.48
, pp. 592-598
-
-
Fleming, E.S.1
Zajac, M.2
Moschenross, D.M.3
Montrose, D.C.4
Rosenberg, D.W.5
-
57
-
-
0028101021
-
Orientation of Spindle Axis and Distribution of Plasma Membrane Proteins During Cell Division in Polarized MDCKII Cells
-
Reinsch S, Karsenti E, (1994) Orientation of Spindle Axis and Distribution of Plasma Membrane Proteins During Cell Division in Polarized MDCKII Cells. The Journal of Cell Biology 126: 1509-1526.
-
(1994)
The Journal of Cell Biology
, vol.126
, pp. 1509-1526
-
-
Reinsch, S.1
Karsenti, E.2
-
58
-
-
32144450233
-
RNA interference techniques to study epithelial cell adhesion and polarity
-
Chen X, Macara IG, (2006) RNA interference techniques to study epithelial cell adhesion and polarity. Methods In Enzymology 406: 362-374.
-
(2006)
Methods In Enzymology
, vol.406
, pp. 362-374
-
-
Chen, X.1
Macara, I.G.2
-
59
-
-
0034253536
-
The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42
-
Joberty G, Petersen C, Gao L, Macara IG, (2000) The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42. Nature Cell Biology 2: 531-539.
-
(2000)
Nature Cell Biology
, vol.2
, pp. 531-539
-
-
Joberty, G.1
Petersen, C.2
Gao, L.3
Macara, I.G.4
-
60
-
-
77952396762
-
Tuba, a Cdc42 GEF, is required for polarized spindle orientation during epithelial cyst formation
-
Qin Y, Meisen WH, Hao Y, Macara IG, (2010) Tuba, a Cdc42 GEF, is required for polarized spindle orientation during epithelial cyst formation. Journal of Cell Biology 189: 661-669.
-
(2010)
Journal of Cell Biology
, vol.189
, pp. 661-669
-
-
Qin, Y.1
Meisen, W.H.2
Hao, Y.3
Macara, I.G.4
-
61
-
-
68449094064
-
The active form of the metabolic sensor: AMP-activated protein kinase (AMPK) directly binds the mitotic apparatus and travels from centrosomes to the spindle midzone during mitosis and cytokinesis
-
Vazquez-Martin A, Oliveras-Ferraros C, Menendez JA, (2009) The active form of the metabolic sensor: AMP-activated protein kinase (AMPK) directly binds the mitotic apparatus and travels from centrosomes to the spindle midzone during mitosis and cytokinesis. Cell Cycle 8: 2385-2398.
-
(2009)
Cell Cycle
, vol.8
, pp. 2385-2398
-
-
Vazquez-Martin, A.1
Oliveras-Ferraros, C.2
Menendez, J.A.3
-
62
-
-
62449138276
-
Mitotic kinase dynamics of the active form of AMPK (phospho-AMPKalphaThr172) in human cancer cells
-
Vazquez-Martin A, Lopez-Bonet E, Oliveras-Ferraros C, Perez-Martinez MC, Bernardo L, et al. (2009) Mitotic kinase dynamics of the active form of AMPK (phospho-AMPKalphaThr172) in human cancer cells. Cell Cycle 8: 788-791.
-
(2009)
Cell Cycle
, vol.8
, pp. 788-791
-
-
Vazquez-Martin, A.1
Lopez-Bonet, E.2
Oliveras-Ferraros, C.3
Perez-Martinez, M.C.4
Bernardo, L.5
-
63
-
-
57349094302
-
AMP-activated protein kinase in skeletal muscle: From structure and localization to its role as a master regulator of cellular metabolism
-
Witczak CA, Sharoff CG, Goodyear LJ, (2008) AMP-activated protein kinase in skeletal muscle: From structure and localization to its role as a master regulator of cellular metabolism. Cellular and Molecular Life Sciences 65: 3737-3755.
-
(2008)
Cellular and Molecular Life Sciences
, vol.65
, pp. 3737-3755
-
-
Witczak, C.A.1
Sharoff, C.G.2
Goodyear, L.J.3
-
64
-
-
33751204464
-
AMP-activated protein kinase regulates the assembly of epithelial tight junctions
-
Zhang L, Li J, Young LH, Caplan MJ, (2006) AMP-activated protein kinase regulates the assembly of epithelial tight junctions. Proc Natl Acad Sci U S A 103: 17272-17277.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 17272-17277
-
-
Zhang, L.1
Li, J.2
Young, L.H.3
Caplan, M.J.4
-
65
-
-
33846521353
-
Regulation of epithelial tight junction assembly and disassembly by AMPK-activated protein kinase
-
Zheng B, Cantley L, (2007) Regulation of epithelial tight junction assembly and disassembly by AMPK-activated protein kinase. Proc Natl Acad Sci U S A 104: 819-822.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 819-822
-
-
Zheng, B.1
Cantley, L.2
-
66
-
-
79952751557
-
Lgr5 intestinal stem cells have high telomerase activity and randomly segregate their chromosomes
-
Schepers AG, Vries R, van den Born M, van deWetering M, Clevers H, (2011) Lgr5 intestinal stem cells have high telomerase activity and randomly segregate their chromosomes. The EMBO Journal 30.
-
(2011)
The EMBO Journal
, vol.30
-
-
Schepers, A.G.1
Vries, R.2
van den Born, M.3
van deWetering, M.4
Clevers, H.5
-
67
-
-
36448980590
-
PtdIns(3,4,5)P3 Regulates Spindle Orientation in Adherent Cells
-
Toyoshima F, Matsumura S, Morimoto H, Mitsushima M, Nishida E, (2007) PtdIns(3,4,5)P3 Regulates Spindle Orientation in Adherent Cells. Developmental Cell 13: 796-811.
-
(2007)
Developmental Cell
, vol.13
, pp. 796-811
-
-
Toyoshima, F.1
Matsumura, S.2
Morimoto, H.3
Mitsushima, M.4
Nishida, E.5
-
69
-
-
0037125996
-
Induction of cyclooxygenase-2 in a mouse model of Peutz-Jeghers polyposis
-
Rossi DJ, Ylikorkala A, Korsisaari N, Salovaara R, Luukko K, et al. (2002) Induction of cyclooxygenase-2 in a mouse model of Peutz-Jeghers polyposis. Proc Natl Acad Sci U S A 99: 12327-12332.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 12327-12332
-
-
Rossi, D.J.1
Ylikorkala, A.2
Korsisaari, N.3
Salovaara, R.4
Luukko, K.5
-
70
-
-
0037022122
-
Assembly of Epithelial Tight Junctions Is Negatively Regulated by Par6
-
Gao L, Joberty G, Macara IG, (2002) Assembly of Epithelial Tight Junctions Is Negatively Regulated by Par6. Current Biology 12: 221-225.
-
(2002)
Current Biology
, vol.12
, pp. 221-225
-
-
Gao, L.1
Joberty, G.2
Macara, I.G.3
-
71
-
-
0032514214
-
Effects of regulated expression of mutant RhoA and Rac1 small GTPases on the development of epithelial (MDCK) cell polarity
-
Jou TS, Nelson WJ, (1998) Effects of regulated expression of mutant RhoA and Rac1 small GTPases on the development of epithelial (MDCK) cell polarity. Journal of Cell Biology 142: 85-100.
-
(1998)
Journal of Cell Biology
, vol.142
, pp. 85-100
-
-
Jou, T.S.1
Nelson, W.J.2
-
72
-
-
0035947235
-
A Role for AMP-Activated Protein Kinase in Contraction- and Hypoxia-Regulated Glucose Transport in Skeletal Muscle
-
Mu J, Brozinick JTJ, Valladares O, Bucan M, Birnbaum MJ, (2001) A Role for AMP-Activated Protein Kinase in Contraction- and Hypoxia-Regulated Glucose Transport in Skeletal Muscle. Molecular Cell 7: 1085-1094.
-
(2001)
Molecular Cell
, vol.7
, pp. 1085-1094
-
-
Mu, J.1
Brozinick, J.T.J.2
Valladares, O.3
Bucan, M.4
Birnbaum, M.J.5
|