Blockade of the Activin Receptor IIB Activates Functional Brown Adipogenesis and Thermogenesis by Inducing Mitochondrial Oxidative Metabolism

Molecular and Cellular Biology

Volumn 32, Issue 14, 2012, Pages 2871-2879

  Fournier, Brigitte ^a   Murray, Ben ^a   Gutzwiller, Sabine ^a   Marcaletti, Stefan ^a   Marcellin, David ^a   Bergling, Sebastian ^a   Brachat, Sophie ^a   Persohn, Elke ^a   Pierrel, Eliane ^a   Bombard, Florian ^a   Hatakeyama, Shinji ^a   Trendelenburg, Anne Ulrike ^b   Morvan, Frederic ^a   Richardson, Brian ^a   Glass, David J ^a,b   Lach Trifilieff, Estelle ^a   Feige, Jerome N ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

^b NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN RECEPTOR 2; MYOGLOBIN; SMAD3 PROTEIN;

ADIPOGENESIS; AEROBIC METABOLISM; ANIMAL EXPERIMENT; ARTICLE; BROWN ADIPOSE TISSUE; COLD TOLERANCE; CONTROLLED STUDY; ENERGY EXPENDITURE; ENVIRONMENTAL TEMPERATURE; MALE; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; THERMOGENESIS;

ACTIVIN RECEPTORS, TYPE II; ADIPOCYTES, BROWN; ADIPOGENESIS; ADIPOSE TISSUE, BROWN; ANIMALS; ANTIBODIES, NEUTRALIZING; CELL DIFFERENTIATION; ENERGY METABOLISM; FEMALE; MALE; MICE; MICE, INBRED C57BL; MICE, SCID; MICE, TRANSGENIC; MICROSCOPY, ELECTRON, TRANSMISSION; MITOCHONDRIA; MUSCLE, SKELETAL; MYOSTATIN; SIGNAL TRANSDUCTION; SMAD3 PROTEIN; THERMOGENESIS; TRANSCRIPTION FACTORS;

MUS;

EID: 84863992227     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.06575-11     Document Type: Article

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