Synthesis and in vitro antitumor activity of novel scopoletin derivatives

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 15, 2012, Pages 5008-5012

  Liu, Wukun ^a,b   Hua, Jie ^c   Zhou, Jinpei ^a   Zhang, Huibin ^a   Zhu, Haiyang ^a   Cheng, Yanhua ^a   Gust, Ronald ^d  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

^c RandD Institute of Jiangsu Jumpcan Pharmaceutical Co Ltd   (China)

^d UNIVERSITY OF INNSBRUCK   (Austria)

Author keywords

Antitumor activity; Scopoletin; Scopoletin derivatives; Synthesis

Indexed keywords

ANTINEOPLASTIC AGENT; SCOPOLETIN; SCOPOLETIN DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; DRUG CYTOTOXICITY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; REACTION ANALYSIS; STRUCTURE ANALYSIS;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; SCOPOLETIN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84863989155     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.06.014     Document Type: Article

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