Synthesis and biological evaluation of hydroxylated 3-phenylcoumarins as antioxidants and antiproliferative agents

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 21, 2011, Pages 6420-6425

  Yang, Jie ^a   Liu, Guo Yun ^a   Dai, Fang ^a   Cao, Xiao Yan ^a   Kang, Yan Fei ^a   Hu, Li Mei ^a   Tang, Jiang Jiang ^a   Li, Xiu Zhuang ^a   Li, Yan ^a   Jin, Xiao Ling ^a   Zhou, Bo ^a  

^a LANZHOU UNIVERSITY   (China)

Author keywords

Antioxidant; Antiproliferative effect; Apoptosis; Coumarin; Hybrid; Resveratrol

Indexed keywords

6 METHOXY 7 HYDROXY 3 (4' HYDROXYPHENYL)COUMARIN; ANTINEOPLASTIC AGENT; ANTIOXIDANT; AROMATIC COMPOUND; AZO COMPOUND; COUMARIN DERIVATIVE; DNA; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CELL COUNT; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE REGULATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DNA STRAND BREAKAGE; DRUG ACTIVITY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; EVALUATION; HUMAN; HUMAN CELL; HYDROXYLATION; IC 50; LUNG ADENOCARCINOMA; PROMYELOCYTIC LEUKEMIA; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION;

EID: 80054775965     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.08.090     Document Type: Article

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