Induction of megakaryocytic differentiation in chronic myelogenous leukemia cell K562 by 3-hydrogenkwadaphnin

Journal of Biochemistry and Molecular Biology

Volumn 40, Issue 6, 2007, Pages 944-951

  Meshkini, Azadeh ^a   Yazdanparast, Razieh ^a  

^a UNIVERSITY OF TEHRAN   (Iran)

Author keywords

Apoptosis; Dendrostellera lessertii; Differentiation; K562 cells; Leukemia

Indexed keywords

DENDROSTELLERA LESSERTII; THYMELAEACEAE;

EID: 36949001366     PISSN: 12258687     EISSN: 02191024     Source Type: Journal    
DOI: 10.5483/bmbrep.2007.40.6.944     Document Type: Article

References (44)

1. Alitalo, R. (1990) Induced differentiation of K562 leukemia cells: a model for studies of gene expression in early megakaryoblasts. Leuk. Res. 14, 501-514.
2. Batiuk, T. D., Schnizlein-Bick, C., Plotkin, Z. and Dagher, P. C. (2001) Guanine nucleosides and Jurkat cell death: roles of ATP depletion and accumulation of deoxyribonucleotides. Am. J. Physiol. Cell Physiol. 281, 1776-1784.
3. Collart, F. R. and Huberman, E. (1990) Expression of IMP dehydrogenase in differentiating HL-60 cells. Blood 75, 570-576.
4. Copland, M., Jorgensen, H. G. and Holyoake, T. L. (2005) Evolving molecular therapy for chronic myeloid leukaemia - are we on target? Hematology 10, 349-359.
5. Hall, I. H., Kasai, R., Wu, R. Y., Tagahara, K. and Lee, K. H. (1982) Antitumor agents LV: effects of genkwadaphnin and yuanhuacine on nucleic acid synthesis of P-388 lymphocytic leukemia cells. J. Pharm. Sci. 71, 1263-1267.
6. Herrera, R., Hubbell, S., Decker, S. and Petruzzelli, L. (1998) A role for the MEK/MAPK pathway in PMA-induced cell cycle arrest: modulation of megakaryocytic differentiation of K562 cells. Exp. Cell Res. 238, 407-414.
7. Honma, Y., Okabe-Kado, J., Hozumi, M., Uehara, Y. and Mizuno, S. (1989) Induction of erythroid differentiation of K562 human leukemic cells by herbimycin A, an inhibitor of tyrosine kinase activity. Cancer Res. 49, 331-334.
8. Inai, K., Tsutani, H., Yamauchi, T., Fukushima, T., Iwasaki, H., Imamura, S., Wano, Y., Nemoto, Y., Naiki, H. and Ueda, T. (2000) Differentiation induction in non-lymphocytic leukemia cells upon treatment with mycophenolate mofetil. Leuk. Res. 24, 761-768.
9. Jayaram, H. N., Cooney, D. A., Grusch, M. and Krupitza, G. (1999) Consequences of IMP dehydrogenase inhibition, and its relationship to cancer and apoptosis. Curr. Med. Chem. 6, 561-574.
10. Koeffler, H. P. and Golde, D. W. (1980) Human myeloid leukemia cell lines: a review. Blood 56, 344-350.
11. Koeffler, H. P. (1983) Induction of differentiation of human acute myelogenous leukemia cells: therapeutic implications. Blood 62, 709-721.
12. Laliberte, J., Yee, A., Xiong, Y. and Mitchell, B. S. (1998) Effects of guanine nucleotide depletion on cell cycle progression in human T lymphocytes. Blood 91, 2896-2904.
13. + cord blood cells to megakaryocytes. Blood 96, 4169-4177.
14. Li, G., Segu, V. B., Rabaglia, M. E., Luo, R. H., Kowluru, A. and Metz, S. A. (1998) Prolonged depletion of guanosine triphosphate induces death of insulin-secreting cells by apoptosis. Endocrinology 139, 3752-3762.
15. Long, M. W., Heffner, C. H., Williams, J. L., Peters, C. and Prochownik, E. V. (1990) Regulation of megakaryocyte phenotype in human erythroleukemia cells. J. Clin. Invest. 85, 1072-1084.
16. Lozzio, B. B. and Lozzio, C. B. (1977) Properties of the K562 cell line derived from a patient with chronic myeloid leukemia. Int. J. Cancer 19, 136.
17. Martin, S. J., Bradley, J. G. and Cotter, T. G. (1990) HL-60 cells induced to differentiate towards neutrophils subsequently die via apoptosis. Clin. Exp. Immunol. 79, 448-453.
18. Moosavi, M. A. and Yazdanparast, R. (2006) Differentiation therapy as an effective strategy for the treatment of chronic myelogenous leukemia. Med. Hypotheses 67, 1470-1471.
19. Moosavi, M. A., Yazdanparast, R. and Sanati, M. H. (2005a) The cytotoxic and anti-proliferative effects of 3-hydrogenkwadaphnin in K562 and jurkat cells is reduced by guanosine. J. Biochem. Mol. Biol. 38, 391-398.
20. Moosavi, M. A., Yazdanparast, R., Sanati, M. H. and Nejad, A. S. (2005b) 3-Hydrogenkwadaphnin targets inosine 5-monophosphate dehydrogenase and triggers post-G1 arrest apoptosis in human leukemia cell lines. Int. J. Biochem. Cell Biol. 37, 2366-2379.
21. Moosavi, M. A., Yazdanparast, R. and Lotfi A. (2006) 3-Hydrogenkwadaphnin induces monocytic differentiation and enhances retinoic acid-mediated granulocytic differentiation in NB4 cell line. J. Biochem. Mol. Biol. 39, 722-729.
22. Morceau, F., Dupont, C., Palissot, V., Borde-Chiche, P., Trentesaux, C., Dicato, M. and Diederich, M. (2000) GTP-mediated differentiation of the human K562 cell line: transient overexpression of GATA-1 and stabilization of the gamma-globin mRNA. Leukemia 14, 1589-1597.
23. Murate, T., Saga, S., Hotta, T., Asano, H., Ito, T., Kato, K., Tsushita, K., Kinoshita, T., Ichikawa, A., Yoshida, S. and Saito, H. (1993) The close relationship between DNA replication and the selection of differentiation lineages of human erythroleukemia cell lines K562, HEL, and TF1 into either erythroid or megakaryocytic lineages. Exp. Cell Res. 208, 35-43.
24. Robinson, J., Sieff, C., Delia, D., Edwards, P. A. and Greaves, M. (1981) Expression of cell-surface HLA-DR, HLA-ABC and glycophorin during erythroid differentiation. Nature 289, 68-71.
25. Rouyez, M. C., Boucheron, C., Gisselbrecht, S., Dusanter-Fourt, I. and Porteu, F. (1997) Control of thrombopoietin-induced megakaryocytic differentiation by the mitogen-activated protein kinase pathway. Mol. Cell Biol. 17, 4991-5000.
26. Sadeghi, H. and Yazdanparast, R. (2005) Isolation and structure elucidation of a new potent anti-neoplastic diterpene from Dendrostellera lessertii. Am. J. Chin. Med. 33, 831-837.
27. Sell, S. (2006) Cancer stem cells and differentiation therapy. Tumor Biol. 27, 59-70.
28. Shu, Y. Z. (1998) Recent natural products based drug development: a pharmaceutical industry perspective. J. Nat. Prod. 61, 1053-1071.
29. Sillaber, C., Mayerhofer, M., Agis, H., Sagaster, V., Mannhalter, C., Sperr, W. R., Geissler, K. and Valent, P. (2003) Chronic myeloid leukemia: pathophysiology, diagnostic parameters, and current treatment concepts. Wien. Klin. Wochenschr. 115, 485-504.
30. Spira, A. I. and Carducci, M. A. (2003) Differentiation therapy. Curr. Opin. Pharmacol. 3, 338-343.
31. Stanoeva, E., He, W. and De Kimpe, N. (2005) Natural and synthetic cage compounds incorporating the 2,9,10-trioxatricyclo [4.3.1.03,8]decane type moiety. Bioorg. Med. Chem. 13, 17-28.
32. Szalai, G., LaRue, A. C. and Watson, D. K. (2006) Molecular mechanisms of megakaryopoiesis. Cell Mol. Life Sci. 63, 2460-2476.
33. Tetteroo, P. A., Massaro, F., Mulder, A., Schreuder-van Gelder, R. and von dem Borne, A. E. (1984) Megakaryoblastic differentiation of proerythroblastic K562 cell-line cells. Leuk. Res. 8, 197-206.
34. Tonini, G. P., Radzioch, D., Gronberg, A., Clayton, M., Blasi, E., Benetton, G. and Varesio, L. (1987) Erythroid differentiation and modulation of c-myc expression induced by antineoplastic drugs in the human leukemic cell line K562. Cancer Res. 47, 4544-4547.
35. Villeval, J. L., Pelicci, P. G., Tabilio, A., Titeux, M., Henri, A., Houesche, F., Thomopoulos, P., Vainchenker, W., Garbaz, M., Rochant, H., Breton-Gorius, J., Edwards, P. A. and Testa, U. (1983) Erythroid properties of K562 cells. Effect of hemin, butyrate and TPA induction. Exp. Cell Res. 146, 428-435.
36. Vitale, M., Zamai, L., Falcieri, E., Zauli, G., Gobbi, P., Santi, S., Cinti, C. and Weber, G. (1997) IMP dehydrogenase inhibitor, tiazofurin, induces apoptosis in K562 human erythroleukemia cells. Cytometry 30, 61-66.
37. Vitrat, N., Cohen-Solal, K., Pique, C., Le Couedic, J. P., Norol, F., Larsen, A. K., Katz, A., Vainchenker, W. and Debili, N. (1998) Endomitosis of human megakaryocytes are due to abortive mitosis. Blood 91, 3711-3723
38. Watson, R. W., Rotstein, O. D., Parodo, J., Bitar, R., Hackam, D. and Marshall, J. C. (1997) Granulocytic differentiation of HL-60 cells results in spontaneous apoptosis mediated by increased caspase expression. FEBS lett. 412, 603-609.
39. Wiernik, P. H., Dutcher, J. P., Paietta, E., Hittelman, W. N., Vyas, R., Strack, M., Castaigne, S., Degos, L. and Gallagher, R. E. (1991) Treatment of promyelocytic blast crisis of chronic myelogenous leukemia with all trans-retinoic acid. Leukemia 5, 504-509.
40. Wilhide, C. C., Van Dang, C., Dipersio, J., Kenedy, A. A. and Bray, P. F. (1995) Overexpression of cyclin D1 in the Dami megakaryocytic cell line causes growth arrest. Blood 86, 294-304.
41. Yazdanparast, R., Mahdavi, M. and Moosavi, M. A. (2006) Induction of differentiation and apoptosis in three human leukemia cell lines by a new compound from Dendrostellera lessertii. Acta Biochim. Biophys. Sin. 38, 477-483.
42. Yazdanparast, R., Moosavi, M. A., Mahdavi, M. and Sanati, H. (2005) 3-Hydrogenkwadaphnin from Dendrostellera lessertii induces differentiation and apoptosis in HL-60 cells. Planta Med. 71, 1112-1117.
43. Yazdanparast, R. and Sadeghi, H. (2004) Nucleic acid synthesis in cancerous cells under the effect of gnidilatimonoein from Daphne mucronata. Life Sci. 74, 1869-1876.
44. Yen, A., Varvayanis, S., Platko, J. D. (1993) 12-O-trtradecanoylphorbol- 13-acetate and staurosporine induce increased retinoblastoma tumor suppressor gene expression with megakaryocytic differentiation of leukemic cells. Cancer Res. 53, 3085-3091.