Scopoletin induces apoptosis in human promyeloleukemic cells, accompanied by activations of nuclear factor κb and caspase-3

Life Sciences

Volumn 77, Issue 7, 2005, Pages 824-836

  Kim, Eun Kyung ^a   Kwon, Kang Beom ^a   Shin, Byung Cheul ^a   Seo, Eun A ^a   Lee, Young Rae ^b   Kim, Jong Suk ^b   Park, Jin Woo ^b   Park, Byung Hyun ^b   Ryu, Do Gon ^a  

^a Wonkwang University   (South Korea)

^b Chonbuk National University   (South Korea)

Author keywords

Apoptosis; Caspase 3; HL 60 cells; NF B; Scopoletin

Indexed keywords

ALDEHYDE DERIVATIVE; ASPARTYLGLUTAMYLVALYLASPARTIC ACID ACETALDEHYDE; CASPASE 3; CASPASE 3 INHIBITOR; DNA FRAGMENT; ENZYME PRECURSOR; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEINASE; PYRROLIDINE DITHIOCARBAMATE; SCOPOLETIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME DEGRADATION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; OXIDATION REDUCTION REACTION; PROMYELOCYTIC LEUKEMIA; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; UPREGULATION;

ANALYSIS OF VARIANCE; APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; CASPASES; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, AGAR GEL; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENZYME ACTIVATION; GRANULOCYTE PRECURSOR CELLS; HL-60 CELLS; HUMANS; I-KAPPA B PROTEINS; NF-KAPPA B; POLY(ADP-RIBOSE) POLYMERASES; PROTEIN TRANSPORT; SCOPOLETIN; SIGNAL TRANSDUCTION; TETRAZOLIUM SALTS; THIAZOLES;

EID: 20344390242     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2005.02.003     Document Type: Article

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