A nucleotide-gated molecular pore selects sulfotransferase substrates

Biochemistry

Volumn 51, Issue 28, 2012, Pages 5674-5683

  Cook, Ian ^a   Wang, Ting ^a   Falany, Charles N ^b   Leyh, Thomas S ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; BIOLOGIC ACTIVITIES; CLOSED FORM; COMPLEX MIXTURE; DEHYDROEPIANDROSTERONE; EQUILIBRIUM BINDING; IN-SILICO; IN-VITRO; IN-VIVO; INITIAL RATE; LIGAND BINDING; MOLECULAR BASIS; MOLECULAR PORES; PRECUSORS; RECEPTOR INTERACTION; SUBSTRATE BINDING; SUBSTRATE SELECTION; SYNTHETIC STEROIDS;

BIOCHEMISTRY; ENZYMES; NUCLEOTIDES;

SUBSTRATES;

ADENOSINE 3' PHOSPHATE 5' PHOSPHOSULFATE; LIVER ENZYME; PRASTERONE; RALOXIFENE; SULFOTRANSFERASE; SULFOTRANSFERASE 1A1;

ARTICLE; CRYSTAL STRUCTURE; DRUG TRANSFORMATION; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; IN VITRO STUDY; IN VIVO STUDY; ISOMERIZATION; NANOPORE; OSTEOPOROSIS; PRIORITY JOURNAL; SULFATION;

BONE DENSITY CONSERVATION AGENTS; COMPUTER SIMULATION; DEHYDROEPIANDROSTERONE; KINETICS; MOLECULAR DOCKING SIMULATION; PHOSPHOADENOSINE PHOSPHOSULFATE; PROTEIN BINDING; RALOXIFENE; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY; SULFOTRANSFERASES;

EID: 84863931141     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi300631g     Document Type: Article

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