Isotope exchange at equilibrium indicates a steady state ordered kinetic mechanism for human sulfotransferase

Biochemistry

Volumn 47, Issue 45, 2008, Pages 11894-11899

  Tyapochkin, Eduard ^a   Cook, Paul F ^b   Chen, Guangping ^a  

^a OKLAHOMA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF OKLAHOMA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL CULTURE; BIOCHEMISTRY; CHEMICAL REACTIONS; DETOXIFICATION; ENZYMES; ISOTOPES; PHENOLS; POLARIZATION; RATE CONSTANTS; REACTION KINETICS;

BIOLOGICAL ACTIVITIES; CATALYZED REACTIONS; CONSTANT RATIOS; CYTOSOLIC; DIPHOSPHATE; DRUG METABOLISMS; EXCHANGE RATES; FIRST ORDERS; FREE ENZYMES; INITIAL CONCENTRATIONS; ISOFORM; ISOTOPE EXCHANGES; ISOTOPIC EXCHANGE REACTIONS; ISOTOPIC EXCHANGES; KINETIC MECHANISMS; PHASE II; REACTION PRODUCTS; STEADY STATES; SUBSTRATE SPECIFICITIES; SULFOTRANSFERASE; TIME SCALES;

EQUILIBRIUM CONSTANTS;

1 NAPHTHOL; 1 NAPHTHYL SULFATE; ADENOSINE 3' PHOSPHATE 5' PHOSPHOSULFATE; CARBON 14; ISOENZYME; ISOTOPE; PHENOL DERIVATIVE; SULFOTRANSFERASE; SULFOTRANSFERASE 1A1; SULFUR 35; UNCLASSIFIED DRUG; XENOBIOTIC AGENT;

ARTICLE; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; EQUILIBRIUM CONSTANT; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STEADY STATE; SULFATION;

CARBON RADIOISOTOPES; CATALYSIS; HUMANS; KINETICS; PHENOL; PHOSPHOADENOSINE PHOSPHOSULFATE; SULFATES; SULFOTRANSFERASES;

EID: 55849116013     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi801211t     Document Type: Article

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