Identification and characterization of two amino acids critical for the substrate inhibition of human dehydroepiandrosterone sulfotransferase (SULT2A1)

Molecular Pharmacology

Volumn 73, Issue 3, 2008, Pages 660-668

  Lu, Lu Yi ^a   Hsieh, Yin Cheng ^c   Liu, Ming Yih ^b   Lin, Yih Hung ^b   Chen, Chun Jung ^b,c   Yang, Yuh Shyong ^a,d,e  

^a NATIONAL CHIAO TUNG UNIVERSITY   (Taiwan)

^b NATIONAL SYNCHROTRON RADIATION RESEARCH CENTER   (Taiwan)

^c NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^d NATIONAL NANO DEVICE LABORATORIES   (Taiwan)

^e NONE   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; AMINO ACID; ANDROSTERONE; METHIONINE; PRASTERONE; SULFOTRANSFERASE; SULFOTRANSFERASE 2A1; TYROSINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME BINDING; ENZYME INHIBITION; HUMAN; HUMAN CELL; MOUSE; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STRUCTURE;

ALANINE; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANDROSTERONE; BINDING SITES; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; HUMANS; KINETICS; METHIONINE; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; SEQUENCE HOMOLOGY, AMINO ACID; SPECTRUM ANALYSIS, RAMAN; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; SULFOTRANSFERASES; X-RAY DIFFRACTION;

EID: 40849137940     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.107.041038     Document Type: Article

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