메뉴 건너뛰기




Volumn 16, Issue 7, 2012, Pages 806-811

Association between the MTHFR C677T polymorphism and recurrent pregnancy loss: A meta-analysis

Author keywords

[No Author keywords available]

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2);

EID: 84863926049     PISSN: 19450265     EISSN: 19450257     Source Type: Journal    
DOI: 10.1089/gtmb.2011.0318     Document Type: Article
Times cited : (47)

References (41)
  • 1
    • 36649028044 scopus 로고    scopus 로고
    • The 5, 10 methylene-tetrahydrofolate reductase C677T mutation and risk of fetal loss: A case series and review of the literature
    • Altomare I, Adler A, Aledort LM (2007) The 5, 10 methylene- tetrahydrofolate reductase C677T mutation and risk of fetal loss: a case series and review of the literature. Thromb J 5:17.
    • (2007) Thromb J , vol.5 , pp. 17
    • Altomare, I.1    Adler, A.2    Aledort, L.M.3
  • 2
  • 5
    • 0022992740 scopus 로고
    • Meta-analysis in clinical trials
    • DOI 10.1016/0197-2456(86)90046-2
    • DerSimonian R, Laird N (1986) Meta-analysis in clinical trials. Control Clin Trials 7:177-188. (Pubitemid 17189972)
    • (1986) Controlled Clinical Trials , vol.7 , Issue.3 , pp. 177-188
    • DerSimonian, R.1    Laird, N.2
  • 7
    • 0030922816 scopus 로고    scopus 로고
    • Bias in meta-analysis detected by a simple, graphical test
    • Egger M, Davey Smith G, Schneider M, et al. (1997) Bias in meta-analysis detected by a simple, graphical test. BMJ 315:629-634. (Pubitemid 27387172)
    • (1997) British Medical Journal , vol.315 , Issue.7109 , pp. 629-634
    • Egger, M.1    Smith, G.D.2    Schneider, M.3    Minder, C.4
  • 8
    • 0029049553 scopus 로고
    • A candidate genetic risk factor for vascular disease: A common mutation in methyle-netetrahydrofolate reductase
    • Frosst P, Blom HJ, Milos R, et al. (1995) A candidate genetic risk factor for vascular disease: a common mutation in methyle-netetrahydrofolate reductase. Nat Genet 10:111-113.
    • (1995) Nat Genet , vol.10 , pp. 111-113
    • Frosst, P.1    Blom, H.J.2    Milos, R.3
  • 9
    • 25844447665 scopus 로고    scopus 로고
    • Association of red blood cell 5-methyltetrahydrofolate and severity of coronary artery disease: A cross-sectional study from Shiraz, southern Iran
    • DOI 10.1007/s00380-004-0823-3
    • Golbahar J, Aminzadeh MA, Sharifkazemi MB, et al. (2005) Association of red blood cell 5-methyltetrahydrofolate and severity of coronary artery disease: a cross-sectional study from Shiraz, southern Iran. Heart Vessels 20:203-206. (Pubitemid 41386804)
    • (2005) Heart and Vessels , vol.20 , Issue.5 , pp. 203-206
    • Golbahar, J.1    Aminzadeh, M.A.2    Sharifkazemi, M.B.3    Rezaian, G.R.4
  • 10
    • 61449135006 scopus 로고    scopus 로고
    • Association of parental hyperhomocysteinemia and C677T Methylene tetrahydrofolate reductase (MTHFR) polymorphism with recurrent pregnancy loss
    • Govindaiah V, Naushad SM, Prabhakara K, et al. (2009) Association of parental hyperhomocysteinemia and C677T Methylene tetrahydrofolate reductase (MTHFR) polymorphism with recurrent pregnancy loss. Clin Biochem 42:380-386.
    • (2009) Clin Biochem , vol.42 , pp. 380-386
    • Govindaiah, V.1    Naushad, S.M.2    Prabhakara, K.3
  • 12
    • 20644436037 scopus 로고    scopus 로고
    • Association of genetic polymorphisms in plasminogen activator inhibitor-1 gene and 5, 10-methylenetetrahydrofolate reductase gene with recurrent early spontaneous abortion
    • Guan LX, Du XY, Wang JX, et al. (2005) [Association of genetic polymorphisms in plasminogen activator inhibitor-1 gene and 5, 10-methylenetetrahydrofolate reductase gene with recurrent early spontaneous abortion]. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 22:330-333.
    • (2005) Zhonghua Yi Xue Yi Chuan Xue Za Zhi , vol.22 , pp. 330-333
    • Guan, L.X.1    Du, X.Y.2    Wang, J.X.3
  • 14
    • 0032891393 scopus 로고    scopus 로고
    • The C677T MTHFR gene mutation is not predictive of risk for recurrent fetal loss
    • DOI 10.1111/j.1365-2141.1999.01319.x
    • Holmes ZR, Regan L, Chilcott I, et al. (1999) The C677T MTHFR gene mutation is not predictive of risk for recurrent fetal loss. Br J Haematol 105:98-101. (Pubitemid 29197149)
    • (1999) British Journal of Haematology , vol.105 , Issue.1 , pp. 98-101
    • Holmes, Z.R.1    Regan, L.2    Chilcott, I.3    Cohen, H.4
  • 15
    • 0037431701 scopus 로고    scopus 로고
    • ABC of antithrombotic therapy: Antithrombotic therapy in special circumstances. II - In children, thrombophilia, and miscellaneous conditions
    • Jilma B, Kamath S, Lip GY (2003) ABC of antithrombotic therapy: Antithrombotic therapy in special circumstances. II-In children, thrombophilia, and miscellaneous conditions. BMJ 326:93-96. (Pubitemid 36092293)
    • (2003) British Medical Journal , vol.326 , Issue.7380 , pp. 93-96
    • Jilma, B.1    Kamath, S.2    Lip, G.Y.H.3
  • 16
  • 17
    • 0037258565 scopus 로고    scopus 로고
    • Plasma homocysteine levels correlated to interactions between folate status and methylene tetrahydrofolate reductase gene mutation in women with unexplained recurrent pregnancy loss
    • DOI 10.1080/0144361021000043263
    • Kumar KS, Govindaiah V, Naushad SE, et al. (2003) Plasma homocysteine levels correlated to interactions between folate status and methylene tetrahydrofolate reductase gene mutation in women with unexplained recurrent pregnancy loss. J Obstet Gynaecol 23:55-58. (Pubitemid 36169553)
    • (2003) Journal of Obstetrics and Gynaecology , vol.23 , Issue.1 , pp. 55-58
    • Kumar, K.S.D.1    Govindaiah, V.2    Naushad, S.E.3    Devi, R.R.4    Jyothy, A.5
  • 18
    • 0032870680 scopus 로고    scopus 로고
    • Polymorphism for mutation of cytosine to thymine at location 677 in the methylenetetrahydrofolate reductase gene is associated with recurrent early fetal loss
    • DOI 10.1016/S0002-9378(99)70447-3
    • Lissak A, Sharon A, Fruchter O, et al. (1999) Polymorphism for mutation of cytosine to thymine at location 677 in the me-thylenetetrahydrofolate reductase gene is associated with recurrent early fetal loss. Am J Obstet Gynecol 181:126-130. (Pubitemid 29343342)
    • (1999) American Journal of Obstetrics and Gynecology , vol.181 , Issue.1 , pp. 126-130
    • Lissak, A.1    Sharon, A.2    Fruchter, O.3    Kassel, A.4    Sanderovitz, J.5    Abramovici, H.6
  • 19
    • 1042288416 scopus 로고    scopus 로고
    • Study on the relationship of MTHFR polymorphisms with unexplained recurrent spontaneous abortion
    • Li X, Zhang Y, Xu X, Jinag S. (2004) Study on the relationship of MTHFR polymorphisms with unexplained recurrent spontaneous abortion. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 21: 39-42. (Pubitemid 38200338)
    • (2004) Chinese Journal of Medical Genetics , vol.21 , Issue.1 , pp. 39-42
    • Li, X.-M.1    Zhang, Y.-Z.2    Xu, Y.-X.3    Jiang, S.4
  • 21
    • 84959801619 scopus 로고
    • Statistical aspects of the analysis of data from retrospective studies of disease
    • Mantel N, Haenszel W (1959) Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst 22:719-748.
    • (1959) J Natl Cancer Inst , vol.22 , pp. 719-748
    • Mantel, N.1    Haenszel, W.2
  • 22
    • 0023848133 scopus 로고
    • Early pregnancy wastage: Relationship between chorionic vascularization and embryonic development
    • Meegdes BH, Ingenhoes R, Peeters LL, et al. (1988) Early pregnancy wastage: relationship between chorionic vascularization and embryonic development. Fertil Steril 49:216-220. (Pubitemid 18047812)
    • (1988) Fertility and Sterility , vol.49 , Issue.2 , pp. 216-220
    • Meegdes, B.H.L.M.1    Ingenhoes, R.2    Peeters, L.L.H.3    Exalto, N.4
  • 23
    • 73949141971 scopus 로고    scopus 로고
    • C677T polymorphism of the methylentetrahydrofolate re-ductase gene as risk factor in women with recurrent abortion
    • Morales-Machin A, Borjas-Fajardo L, Quintero JM, et al. (2009) [C677T polymorphism of the methylentetrahydrofolate re-ductase gene as risk factor in women with recurrent abortion]. Invest Clin 50:327-333.
    • (2009) Invest Clin , vol.50 , pp. 327-333
    • Morales-Machin, A.1    Borjas-Fajardo, L.2    Quintero, J.M.3
  • 24
    • 33244479387 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase C677T and A1298C polymorphism and changes in homocysteine concentrations in women with idiopathic recurrent pregnancy losses
    • DOI 10.1530/rep.1.00815
    • Mtiraoui N, Zammiti W, Ghazouani L, et al. (2006) Methylene- tetrahydrofolate reductase C677T and A1298C polymorphism and changes in homocysteine concentrations in women with idiopathic recurrent pregnancy losses. Reproduction 131:395-401. (Pubitemid 43273699)
    • (2006) Reproduction , vol.131 , Issue.2 , pp. 395-401
    • Mtiraoui, N.1    Zammiti, W.2    Ghazouani, L.3    Braham, N.J.4    Saidi, S.5    Finan, R.R.6    Almawi, W.Y.7    Mahjoub, T.8
  • 25
    • 75649091533 scopus 로고    scopus 로고
    • MTHFR C677T and factor v Leiden in recurrent pregnancy loss: A study among an endogamous group in North India
    • Mukhopadhyay R, Saraswathy KN, Ghosh PK (2009) MTHFR C677T and factor V Leiden in recurrent pregnancy loss: a study among an endogamous group in North India.Genet Test Mol Biomarkers 13:861-865.
    • (2009) Genet Test Mol Biomarkers , vol.13 , pp. 861-865
    • Mukhopadhyay, R.1    Saraswathy, K.N.2    Ghosh, P.K.3
  • 28
    • 0343471524 scopus 로고    scopus 로고
    • Genetic risk factor for unexplained recurrent early pregnancy loss [1]
    • Nelen WL, Steegers EA, Eskes TK, et al. (1997) Genetic risk factor for unexplained recurrent early pregnancy loss. Lancet 350:861. (Pubitemid 27404349)
    • (1997) Lancet , vol.350 , Issue.9081 , pp. 861
    • Nelen, W.L.D.M.1    Steegers, E.A.P.2    Eskes, T.K.A.B.3    Blom, H.J.4
  • 31
    • 0031883045 scopus 로고    scopus 로고
    • A woman with five consecutive fetal deaths: Case report and retrospective analysis of hyperhomocysteinemia prevalence in 100 consecutive women with recurrent miscarriages
    • DOI 10.1016/S0015-0282(97)00451-2, PII S0015028297004512
    • Quere I, Bellet H, Hoffet M, et al. (1998) A woman with five consecutive fetal deaths: case report and retrospective analysis of hyperhomocysteinemia prevalence in 100 consecutive women with recurrent miscarriages. Fertil Steril 69:152-154. (Pubitemid 28073011)
    • (1998) Fertility and Sterility , vol.69 , Issue.1 , pp. 152-154
    • Quere, I.1    Bellet, H.2    Hoffet, M.3    Janbon, C.4    Mares, P.5    Gris, J.-C.6
  • 32
    • 0036149892 scopus 로고    scopus 로고
    • Thrombophilia is common in women with idiopathic pregnancy loss and is associated with late pregnancy wastage
    • DOI 10.1016/S0015-0282(01)02971-5, PII S0015028201029715
    • Sarig G, Younis JS, Hoffman R, et al. (2002) Thrombophilia is common in women with idiopathic pregnancy loss and is associated with late pregnancy wastage. Fertil Steril 77:342-347. (Pubitemid 34086913)
    • (2002) Fertility and Sterility , vol.77 , Issue.2 , pp. 342-347
    • Sarig, G.1    Younis, J.S.2    Hoffman, R.3    Lanir, N.4    Blumenfeld, Z.5    Brenner, B.6
  • 33
    • 84055190849 scopus 로고    scopus 로고
    • Methylenetetrahy-drofolate reductase gene polymorphisms in Egyptian women with unexplained recurrent pregnancy loss
    • Settin A, Elshazli R, Salama A, et al. (2011) Methylenetetrahy-drofolate reductase gene polymorphisms in Egyptian women with unexplained recurrent pregnancy loss. Genet Test Mol Biomarkers 15:887-892.
    • (2011) Genet Test Mol Biomarkers , vol.15 , pp. 887-892
    • Settin, A.1    Elshazli, R.2    Salama, A.3
  • 34
    • 33751184044 scopus 로고    scopus 로고
    • Relationship between genetic polymorphism of homocysteine metabolism enzyme and unexplained repeated spontaneous abortion
    • Song LY (2005) Relationship between genetic polymorphism of homocysteine metabolism enzyme and unexplained repeated spontaneous abortion. Zhonghua Wei Chan Yi Xue Za Zhi 8:160-164.
    • (2005) Zhonghua Wei Chan Yi Xue Za Zhi , vol.8 , pp. 160-164
    • Song, L.Y.1
  • 35
    • 0025708282 scopus 로고
    • Recurrent miscarriage
    • Stirrat GM (1990) Recurrent miscarriage. Lancet 336:673-675.
    • (1990) Lancet , vol.336 , pp. 673-675
    • Stirrat, G.M.1
  • 36
    • 49449114648 scopus 로고    scopus 로고
    • Homocysteine, MTHFR gene polymorphisms, and cardio-cerebrovascular risk
    • Trabetti E (2008) Homocysteine, MTHFR gene polymorphisms, and cardio-cerebrovascular risk. J Appl Genet 49:267-282.
    • (2008) J Appl Genet , vol.49 , pp. 267-282
    • Trabetti, E.1
  • 38
    • 4644240521 scopus 로고    scopus 로고
    • C677T and A1298C mutation of the methylenetetrahydrofolate reductase gene in unexplained recurrent spontaneous abortion
    • Wang XP, Lin QD, Ma ZW, et al. (2004) [C677T and A1298C mutation of the methylenetetrahydrofolate reductase gene in unexplained recurrent spontaneous abortion]. Zhonghua Fu Chan Ke Za Zhi 39:238-241.
    • (2004) Zhonghua Fu Chan Ke Za Zhi , vol.39 , pp. 238-241
    • Wang, X.P.1    Lin, Q.D.2    Ma, Z.W.3
  • 39
    • 33751176953 scopus 로고    scopus 로고
    • The study on the relationship between the methylenetetrahydofolaye reductase 667C T mutation and unexpected recurrent pregnancy loss
    • Wang YW, Li F, Li YP, et al. (2002) The study on the relationship between the methylenetetrahydofolaye reductase 667C T mutation and unexpected recurrent pregnancy loss. Zhongguo Shi Yong Fu Ke Yu Chan Ke Za Zhi 18:291-293.
    • (2002) Zhongguo Shi Yong Fu Ke Yu Chan Ke Za Zhi , vol.18 , pp. 291-293
    • Wang, Y.W.1    Li, F.2    Li, Y.P.3
  • 40
    • 0033754115 scopus 로고    scopus 로고
    • Primary habitual abortions are associated with high frequency of factor v Leiden mutation
    • Wramsby ML, Sten-Linder M, Bremme K (2000) Primary habitual abortions are associated with high frequency of factor V Leiden mutation. Fertil Steril 74:987-991.
    • (2000) Fertil Steril , vol.74 , pp. 987-991
    • Wramsby, M.L.1    Sten-Linder, M.2    Bremme, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.