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Volumn 4, Issue 3, 2012, Pages 408-412

Clinical significance of GADD153 expression in stage I non-small cell lung cancer

Author keywords

Growth arrest and DNA damage inducible gene; Immunohistochemistry; Non small cell lung cancer; Prognosis

Indexed keywords

GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153;

EID: 84863873900     PISSN: 17921074     EISSN: 17921082     Source Type: Journal    
DOI: 10.3892/ol.2012.768     Document Type: Article
Times cited : (8)

References (35)
  • 4
    • 0024990364 scopus 로고
    • Isolation and characterization of the hamster gadd153 gene. Activation of promoter activity by agents that damage DNA
    • Luethy JD, Fargnoli J, Park JS, Fornace AJ Jr and HolbrookNJ: Isolation and characterization of the hamster gadd153 gene. Activation of promoter activity by agents that damage DNA. J Biol Chem 265: 16521-16526, 1990.
    • (1990) J Biol Chem , vol.265 , pp. 16521-16526
    • Luethy, J.D.1    Fargnoli, J.2    Park, J.S.3    Fornace Jr., A.J.4    Holbrook, N.J.5
  • 5
    • 0026546365 scopus 로고
    • CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription
    • Ron D and Habener JF: CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription. Genes Dev 6: 439-453, 1992.
    • (1992) Genes Dev , vol.6 , pp. 439-453
    • Ron, D.1    Habener, J.F.2
  • 6
    • 0036683653 scopus 로고    scopus 로고
    • CCAAT/enhancer-binding proteins: Structure, function and regulation
    • Ramji DP and Foka P: CCAAT/enhancer-binding proteins: structure, function and regulation. Biochem J 365: 561-575, 2002.
    • (2002) Biochem J , vol.365 , pp. 561-575
    • Ramji, D.P.1    Foka, P.2
  • 7
    • 0035504022 scopus 로고    scopus 로고
    • Inhibition of CHOP translation by a peptide encoded by an open reading frame localized in the chop 5'UTR
    • Jousse C, Bruhat A, Carraro V, et al: Inhibition of CHOP translation by a peptide encoded by an open reading frame localized in the chop 5'UTR. Nucleic Acids Res 29: 4341-4351, 2001.
    • (2001) Nucleic Acids Res , vol.29 , pp. 4341-4351
    • Jousse, C.1    Bruhat, A.2    Carraro, V.3
  • 8
    • 0027988165 scopus 로고
    • Genotoxic stress confers preferential and coordinate messenger RNA stability on the five gadd genes
    • Jackman J, Alamo I, Jr and Fornace AJ Jr: Genotoxic stress confers preferential and coordinate messenger RNA stability on the five gadd genes. Cancer Res 54: 5656-5662, 1994.
    • (1994) Cancer Res , vol.54 , pp. 5656-5662
    • Jackman, J.1    Alamo Jr., I.2    Fornace Jr., A.J.3
  • 9
    • 8944259440 scopus 로고    scopus 로고
    • Signals from the stressed endoplasmic reticulum induce C/EBP-homologous protein (CHOP/GADD153)
    • Wang XZ, Lawson B, Brewer JW, et al: Signals from the stressed endoplasmic reticulum induce C/EBP-homologous protein (CHOP/GADD153). Mol Cell Biol 16: 4273-4280, 1996.
    • (1996) Mol Cell Biol , vol.16 , pp. 4273-4280
    • Wang, X.Z.1    Lawson, B.2    Brewer, J.W.3
  • 10
    • 0030814110 scopus 로고    scopus 로고
    • Amino acid limitation induces expression of CHOP, a CCAAT/enhancer binding protein-related gene, at both transcriptional and post-transcriptional levels
    • Bruhat A, Jousse C, Wang XZ, Ron D, Ferrara M and FafournouxP: Amino acid limitation induces expression of CHOP, a CCAAT/enhancer binding protein-related gene, at both transcriptional and post-transcriptional levels. J Biol Chem 272: 17588-17593, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 17588-17593
    • Bruhat, A.1    Jousse, C.2    Wang, X.Z.3    Ron, D.4    Ferrara, M.5    Fafournoux, P.6
  • 11
    • 0033671650 scopus 로고    scopus 로고
    • Upregulation of BiP and CHOP by the unfolded-protein response is independent of presenilin expression
    • Sato N, Urano F, Yoon Leem J, et al: Upregulation of BiP and CHOP by the unfolded-protein response is independent of presenilin expression. Nat Cell Biol 2: 863-870, 2000.
    • (2000) Nat Cell Biol , vol.2 , pp. 863-870
    • Sato, N.1    Urano, F.2    Yoon Leem, J.3
  • 12
    • 20444399528 scopus 로고    scopus 로고
    • Expression of endoplasmic reticulum molecular chaperone Grp78 in human lung cancer and its clinical significance
    • Uramoto H, Sugio K, Oyama T, et al: Expression of endoplasmic reticulum molecular chaperone Grp78 in human lung cancer and its clinical significance. Lung Cancer 49: 55-62, 2005.
    • (2005) Lung Cancer , vol.49 , pp. 55-62
    • Uramoto, H.1    Sugio, K.2    Oyama, T.3
  • 13
    • 19944429106 scopus 로고    scopus 로고
    • GRP78 expression correlates with histologic differentiation and favorable prognosis in neuroblastic tumors
    • Hsu WM, Hsieh FJ, Jeng YM, et al: GRP78 expression correlates with histologic differentiation and favorable prognosis in neuroblastic tumors. Int J Cancer 113: 920-927, 2005.
    • (2005) Int J Cancer , vol.113 , pp. 920-927
    • Hsu, W.M.1    Hsieh, F.J.2    Jeng, Y.M.3
  • 14
    • 0030597160 scopus 로고    scopus 로고
    • Ectopic expression of CHOP (GADD153) induces apoptosis in M1 myeloblastic leukemia cells
    • Matsumoto M, Minami M, Takeda K, Sakao Y and Akira S: Ectopic expression of CHOP (GADD153) induces apoptosis in M1 myeloblastic leukemia cells. FEBS Lett 395: 143-147, 1996.
    • (1996) FEBS Lett , vol.395 , pp. 143-147
    • Matsumoto, M.1    Minami, M.2    Takeda, K.3    Sakao, Y.4    Akira, S.5
  • 15
    • 23444443039 scopus 로고
    • CHOP (GADD153) and its oncogenic variant, TLS-CHOP, have opposing effects on the induction of G1/S arrest
    • Barone MV, Crozat A, Tabaee A, Philipson L and Ron D: CHOP (GADD153) and its oncogenic variant, TLS-CHOP, have opposing effects on the induction of G1/S arrest. Genes Dev 8: 453-464, 1994.
    • (1994) Genes Dev , vol.8 , pp. 453-464
    • Barone, M.V.1    Crozat, A.2    Tabaee, A.3    Philipson, L.4    Ron, D.5
  • 16
    • 0035879276 scopus 로고    scopus 로고
    • Stress-inducible transcription factor CHOP/gadd153 induces apoptosis in mammalian cells via p38 kinase-dependent and-independent mechanisms
    • Maytin EV, Ubeda M, Lin JC and Habener JF: Stress-inducible transcription factor CHOP/gadd153 induces apoptosis in mammalian cells via p38 kinase-dependent and-independent mechanisms. Exp Cell Res 267: 193-204, 2001.
    • (2001) Exp Cell Res , vol.267 , pp. 193-204
    • Maytin, E.V.1    Ubeda, M.2    Lin, J.C.3    Habener, J.F.4
  • 17
    • 1842843855 scopus 로고    scopus 로고
    • Roles of CHOP/GADD153 in endoplasmic reticulum stress
    • Oyadomari S and Mori M: Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ 11: 381-389, 2004.
    • (2004) Cell Death Differ , vol.11 , pp. 381-389
    • Oyadomari, S.1    Mori, M.2
  • 18
    • 0028811996 scopus 로고
    • Incidence of local recurrence and second primary tumors in resected stage I lung cancer
    • Martini N, Bains MS, Burt ME, et al: Incidence of local recurrence and second primary tumors in resected stage I lung cancer. J Thorac Cardiovasc Surg 109: 120-129, 1995.
    • (1995) J Thorac Cardiovasc Surg , vol.109 , pp. 120-129
    • Martini, N.1    Bains, M.S.2    Burt, M.E.3
  • 19
    • 0037264633 scopus 로고    scopus 로고
    • Targeting RAS signalling pathways in cancer therapy
    • Downward J: Targeting RAS signalling pathways in cancer therapy. Nat Rev Cancer 3: 11-22, 2003.
    • (2003) Nat Rev Cancer , vol.3 , pp. 11-22
    • Downward, J.1
  • 20
    • 1642553461 scopus 로고    scopus 로고
    • The dark side of Ras: Regulation of apoptosis
    • Cox AD and Der CJ: The dark side of Ras: regulation of apoptosis. Oncogene 22: 8999-9006, 2003.
    • (2003) Oncogene , vol.22 , pp. 8999-9006
    • Cox, A.D.1    Der, C.J.2
  • 21
    • 0032481146 scopus 로고    scopus 로고
    • Downregulation of the pro-apoptotic protein Bak is required for the ras-induced transformation of intestinal epithelial cells
    • Rosen K, Rak J, Jin J, Kerbel RS, Newman MJ and Filmus J: Downregulation of the pro-apoptotic protein Bak is required for the ras-induced transformation of intestinal epithelial cells. Curr Biol 8: 1331-1334, 1998.
    • (1998) Curr Biol , vol.8 , pp. 1331-1334
    • Rosen, K.1    Rak, J.2    Jin, J.3    Kerbel, R.S.4    Newman, M.J.5    Filmus, J.6
  • 22
    • 0033570912 scopus 로고    scopus 로고
    • The downregulation of the pro-apoptotic protein Par-4 is critical for Ras-induced survival and tumor progression
    • Barradas M, Monjas A, Diaz-Meco MT, Serrano M and MoscatJ: The downregulation of the pro-apoptotic protein Par-4 is critical for Ras-induced survival and tumor progression. EMBO J 18: 6362-6369, 1999.
    • (1999) EMBO J , vol.18 , pp. 6362-6369
    • Barradas, M.1    Monjas, A.2    Diaz-Meco, M.T.3    Serrano, M.4    Moscat, J.5
  • 24
    • 0033604464 scopus 로고    scopus 로고
    • Negative regulation of Par-4 by oncogenic Ras is essential for cellular transformation
    • Qiu SG, Krishnan S, el-Guendy N and Rangnekar VM: Negative regulation of Par-4 by oncogenic Ras is essential for cellular transformation. Oncogene 18: 7115-7123, 1999.
    • (1999) Oncogene , vol.18 , pp. 7115-7123
    • Qiu, S.G.1    Krishnan, S.2    el-Guendy, N.3    Rangnekar, V.M.4
  • 25
    • 23044461886 scopus 로고    scopus 로고
    • Oncogenic Ras-mediated downregulation of Gadd153/CHOP is required for Ras-induced cellular transformation
    • Rong R, Montalbano J, Jin W, et al: Oncogenic Ras-mediated downregulation of Gadd153/CHOP is required for Ras-induced cellular transformation. Oncogene 24: 4867-4872, 2005.
    • (2005) Oncogene , vol.24 , pp. 4867-4872
    • Rong, R.1    Montalbano, J.2    Jin, W.3
  • 26
    • 0029938805 scopus 로고    scopus 로고
    • Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase
    • Wang XZ and Ron D: Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase. Science 272: 1347-1349, 1996.
    • (1996) Science , vol.272 , pp. 1347-1349
    • Wang, X.Z.1    Ron, D.2
  • 27
    • 10044269621 scopus 로고    scopus 로고
    • Increased GADD gene expression in human colon epithelial cells exposed to deoxycholate
    • Scott DW, Mutamba S, Hopkins RG and Loo G: Increased GADD gene expression in human colon epithelial cells exposed to deoxycholate. J Cell Physiol 202: 295-303, 2005.
    • (2005) J Cell Physiol , vol.202 , pp. 295-303
    • Scott, D.W.1    Mutamba, S.2    Hopkins, R.G.3    Loo, G.4
  • 28
    • 34250758642 scopus 로고    scopus 로고
    • ER stress triggers apoptosis by activating BH3-only protein Bim
    • Puthalakath H, O'Reilly LA, Gunn P, et al: ER stress triggers apoptosis by activating BH3-only protein Bim. Cell 129: 1337-1349, 2007.
    • (2007) Cell , vol.129 , pp. 1337-1349
    • Puthalakath, H.1    O'Reilly, L.A.2    Gunn, P.3
  • 29
    • 0035144493 scopus 로고    scopus 로고
    • Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state
    • McCullough KD, Martindale JL, Klotz LO, Aw TY and HolbrookNJ: Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state. Mol Cell Biol 21: 1249-1259, 2001.
    • (2001) Mol Cell Biol , vol.21 , pp. 1249-1259
    • McCullough, K.D.1    Martindale, J.L.2    Klotz, L.O.3    Aw, T.Y.4    Holbrook, N.J.5
  • 30
    • 0029901711 scopus 로고    scopus 로고
    • GADD153/CHOP, a DNA damage-inducible protein, reduced CAAT/enhancer binding protein activities and increased apoptosis in 32D c13 myeloid cells
    • Friedman AD: GADD153/CHOP, a DNA damage-inducible protein, reduced CAAT/enhancer binding protein activities and increased apoptosis in 32D c13 myeloid cells. Cancer Res 56: 3250-3256, 1996.
    • (1996) Cancer Res , vol.56 , pp. 3250-3256
    • Friedman, A.D.1
  • 31
    • 0037064097 scopus 로고    scopus 로고
    • GADD153-mediated anticancer effects of N-(4-hydroxyphenyl)retinamide on human hepatoma cells
    • Kim DG, You KR, Liu MJ, Choi YK and Won YS: GADD153-mediated anticancer effects of N-(4-hydroxyphenyl)retinamide on human hepatoma cells. J Biol Chem 277: 38930-38938, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 38930-38938
    • Kim, D.G.1    You, K.R.2    Liu, M.J.3    Choi, Y.K.4    Won, Y.S.5
  • 32
    • 0036837429 scopus 로고    scopus 로고
    • Upregulation of GADD153 expression in the apoptotic signaling of N-(4-hydroxyphenyl)retinamide (4HPR)
    • Xia Y, Wong NS, Fong WF and Tideman H: Upregulation of GADD153 expression in the apoptotic signaling of N-(4-hydroxyphenyl)retinamide (4HPR). Int J Cancer 102: 7-14, 2002.
    • (2002) Int J Cancer , vol.102 , pp. 7-14
    • Xia, Y.1    Wong, N.S.2    Fong, W.F.3    Tideman, H.4
  • 33
    • 0036067880 scopus 로고    scopus 로고
    • GADD153 is an independent prognostic factor in melanoma: Immunohistochemical and molecular genetic analysis
    • Korabiowska M, Cordon-Cardo C, Betke H, et al: GADD153 is an independent prognostic factor in melanoma: immunohistochemical and molecular genetic analysis. Histol Histopathol 17: 805-811, 2002.
    • (2002) Histol Histopathol , vol.17 , pp. 805-811
    • Korabiowska, M.1    Cordon-Cardo, C.2    Betke, H.3
  • 34
    • 0034181477 scopus 로고    scopus 로고
    • Increased expression of the transcription factors CCAAT-enhancer binding protein-beta (C/EBBeta) and C/EBzeta (CHOP) correlate with invasiveness of human colorectal cancer
    • Rask K, Thorn M, Ponten F, et al: Increased expression of the transcription factors CCAAT-enhancer binding protein-beta (C/EBBeta) and C/EBzeta (CHOP) correlate with invasiveness of human colorectal cancer. Int J Cancer 86: 337-343, 2000.
    • (2000) Int J Cancer , vol.86 , pp. 337-343
    • Rask, K.1    Thorn, M.2    Ponten, F.3
  • 35
    • 84862518603 scopus 로고    scopus 로고
    • Expression of ER stress and autophagy-related molecules in human non-small cell lung cancer and premalignant lesions
    • Sept 27, (Epub ahead of print)
    • Kim KM, Yu TK, Chu HH, et al: Expression of ER stress and autophagy-related molecules in human non-small cell lung cancer and premalignant lesions. Int J Cancer: Sept 27, 2011 (Epub ahead of print).
    • (2011) Int J Cancer
    • Kim, K.M.1    Yu, T.K.2    Chu, H.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.