Tumor Cells Require Thymidylate Kinase to Prevent dUTP Incorporation during DNA Repair

Cancer Cell

Volumn 22, Issue 1, 2012, Pages 36-50

  Hu, Chun Mei ^a   Yeh, Ming Tyng ^b   Tsao, Ning ^c   Chen, Chih Wei ^a   Gao, Quan Ze ^a   Chang, Chia Yun ^a   Lee, Ming Hsiang ^c   Fang, Jim Min ^b   Sheu, Sheh Yi ^a   Lin, Chow Jaw ^a   Tseng, Mei Chun ^d   Chen, Yu Ju ^d   Chang, Zee Fen ^a  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^d INSTITUTE OF CHEMISTRY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; DEOXYURIDINE TRIPHOSPHATE PYROPHOSPHATASE; DOXORUBICIN; ETHYL 4 (2 (4,6 DIMETHYL 3 OXOISOTHIAZOLO[5,4 B]PYRIDIN 2(3H) YL)ACETYL)PIPERAZINE 1 CARBOXYLATE; HISTONE H2AX; PHOSPHOTRANSFERASE; PHOSPHOTRANSFERASE INHIBITOR; RIBONUCLEOTIDE REDUCTASE; THYMIDYLATE KINASE; UNCLASSIFIED DRUG; YMU1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CELL GROWTH; CONTROLLED STUDY; DNA REPAIR; DOUBLE STRANDED DNA BREAK; DRUG SENSITIZATION; DRUG SYNTHESIS; ENZYME BINDING; GENE SILENCING; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR GROWTH; TUMOR VOLUME; TUMOR XENOGRAFT;

EID: 84863759637     PISSN: 15356108     EISSN: 18783686     Source Type: Journal    
DOI: 10.1016/j.ccr.2012.04.038     Document Type: Article

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