-
1
-
-
0023925454
-
Interactions between deoxyribonucleotide and DNA synthesis
-
Reichard P. Interactions between deoxyribonucleotide and DNA synthesis. Annu Rev Biochem 1988;57:349-74.
-
(1988)
Annu Rev Biochem
, vol.57
, pp. 349-374
-
-
Reichard, P.1
-
2
-
-
0029162556
-
Mammalian deoxyribonucleoside kinases
-
Arner ES, Eriksson S. Mammalian deoxyribonucleoside kinases. Pharmacol Ther 1995;67:155-86.
-
(1995)
Pharmacol Ther
, vol.67
, pp. 155-186
-
-
Arner, E.S.1
Eriksson, S.2
-
3
-
-
0038387494
-
5-Fluorouracil: Mechanisms of action and clinical strategies
-
Longley DB, Harkin DP, Johnston PG. 5-Fluorouracil: mechanisms of action and clinical strategies. Nat Rev Cancer 2003;3:330-8.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 330-338
-
-
Longley, D.B.1
Harkin, D.P.2
Johnston, P.G.3
-
5
-
-
0034906625
-
Thymidine kinase, thymidylate synthase, and dihydropyrimidine dehydrogenase profiles of cell lines of the National Cancer Institute's Anticancer Drug Screen
-
Grem JL, Danenberg KD, Behan K, et al. Thymidine kinase, thymidylate synthase, and dihydropyrimidine dehydrogenase profiles of cell lines of the National Cancer Institute's Anticancer Drug Screen. Clin Cancer Res 2001;7:999-1009.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 999-1009
-
-
Grem, J.L.1
Danenberg, K.D.2
Behan, K.3
-
6
-
-
0032797555
-
Increased cytotoxicity and bystander effect of 5-fluorouracil and 5-deoxy-5-fluorouridine in human colorectal cancer cells transfected with thymidine phosphorylase
-
Evrard A, Cuq P, Ciccolini J, Vian L, Cano JP. Increased cytotoxicity and bystander effect of 5-fluorouracil and 5-deoxy-5-fluorouridine in human colorectal cancer cells transfected with thymidine phosphorylase. Br J Cancer 1999;80:1726-33.
-
(1999)
Br J Cancer
, vol.80
, pp. 1726-1733
-
-
Evrard, A.1
Cuq, P.2
Ciccolini, J.3
Vian, L.4
Cano, J.P.5
-
9
-
-
0028940399
-
Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors
-
Johnston PG, Lenz HJ, Leichman CG, et al. Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors. Cancer Res 1995;55:1407-12.
-
(1995)
Cancer Res
, vol.55
, pp. 1407-1412
-
-
Johnston, P.G.1
Lenz, H.J.2
Leichman, C.G.3
-
10
-
-
0036533805
-
Thymidylate synthase levels: Prognostic, predictive, or both?
-
Allegra C. Thymidylate synthase levels: prognostic, predictive, or both? J Clin Oncol 2002;20:1711-3.
-
(2002)
J Clin Oncol
, vol.20
, pp. 1711-1713
-
-
Allegra, C.1
-
11
-
-
0037440051
-
Prognostic value of thymidylate synthase, Ki-67, and p53 in patients with Dukes' B and C colon cancer: A National Cancer Institute-National Surgical Adjuvant Breast and Bowel Project collaborative study
-
Allegra CJ, Paik S, Colangelo LH, et al. Prognostic value of thymidylate synthase, Ki-67, and p53 in patients with Dukes' B and C colon cancer: a National Cancer Institute-National Surgical Adjuvant Breast and Bowel Project collaborative study. J Clin Oncol 2003;21:241-50.
-
(2003)
J Clin Oncol
, vol.21
, pp. 241-250
-
-
Allegra, C.J.1
Paik, S.2
Colangelo, L.H.3
-
12
-
-
33847745417
-
Changes in the status of p53 affect drug sensitivity to thymidylate synthase (TS) inhibitors by altering TS levels
-
Giovannetti E, Backus HH, Wouters D, et al. Changes in the status of p53 affect drug sensitivity to thymidylate synthase (TS) inhibitors by altering TS levels. Br J Cancer 2007;96:769-75.
-
(2007)
Br J Cancer
, vol.96
, pp. 769-775
-
-
Giovannetti, E.1
Backus, H.H.2
Wouters, D.3
-
13
-
-
0642374238
-
A role for DNA mismatch repair in sensing and responding to fluoropyrimidine damage
-
Meyers M, Hwang A, Wagner MW, et al. A role for DNA mismatch repair in sensing and responding to fluoropyrimidine damage. Oncogene 2003;22:7376-88.
-
(2003)
Oncogene
, vol.22
, pp. 7376-7388
-
-
Meyers, M.1
Hwang, A.2
Wagner, M.W.3
-
14
-
-
0027451668
-
p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
-
Lowe SW, Ruley HE, Jacks T, Housman DE. p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 1993;74:957-67.
-
(1993)
Cell
, vol.74
, pp. 957-967
-
-
Lowe, S.W.1
Ruley, H.E.2
Jacks, T.3
Housman, D.E.4
-
15
-
-
0032701521
-
Disruption of p53 in human cancer cells alters the responses to therapeutic agents
-
Bunz F, Hwang PM, Torrance C, et al. Disruption of p53 in human cancer cells alters the responses to therapeutic agents. J Clin Invest 1999;104:263-9.
-
(1999)
J Clin Invest
, vol.104
, pp. 263-269
-
-
Bunz, F.1
Hwang, P.M.2
Torrance, C.3
-
17
-
-
0017698076
-
Human thymidylate kinase. Purification, characterization, and kinetic behavior of the thymidylate kinase derived from chronic myelocytic leukemia
-
Lee LS, Cheng Y. Human thymidylate kinase. Purification, characterization, and kinetic behavior of the thymidylate kinase derived from chronic myelocytic leukemia. J Biol Chem 1977;252:5686-91.
-
(1977)
J Biol Chem
, vol.252
, pp. 5686-5691
-
-
Lee, L.S.1
Cheng, Y.2
-
18
-
-
0032553485
-
Requirement for p53 and p21 to sustain G2 arrest after DNA damage
-
Bunz F, Dutriaux A, Lengauer C, et al. Requirement for p53 and p21 to sustain G2 arrest after DNA damage. Science 1998;282:1497-501.
-
(1998)
Science
, vol.282
, pp. 1497-1501
-
-
Bunz, F.1
Dutriaux, A.2
Lengauer, C.3
-
19
-
-
33748438866
-
Optimization and functional effects of stable short hairpin RNA expression in primary human lymphocytes via lentiviral vectors
-
An DS, Qin FX, Auyeung VC, et al. Optimization and functional effects of stable short hairpin RNA expression in primary human lymphocytes via lentiviral vectors. Mol Ther 2006;14:494-504.
-
(2006)
Mol Ther
, vol.14
, pp. 494-504
-
-
An, D.S.1
Qin, F.X.2
Auyeung, V.C.3
-
20
-
-
33749681890
-
Delivery of RNA interference
-
Li CX, Parker A, Menocal E, Xiang S, Borodyansky L, Fruehauf JH. Delivery of RNA interference. Cell Cycle 2006;5:2103-9.
-
(2006)
Cell Cycle
, vol.5
, pp. 2103-2109
-
-
Li, C.X.1
Parker, A.2
Menocal, E.3
Xiang, S.4
Borodyansky, L.5
Fruehauf, J.H.6
-
21
-
-
33645752057
-
Tumor vascular targeting therapy with viral vectors
-
Liu Y, Deisseroth A. Tumor vascular targeting therapy with viral vectors. Blood 2006;107:3027-33.
-
(2006)
Blood
, vol.107
, pp. 3027-3033
-
-
Liu, Y.1
Deisseroth, A.2
-
22
-
-
0016647722
-
Adriamycin - a review
-
Carter SK. Adriamycin - a review. J Natl Cancer Inst 1975;55:1265-74.
-
(1975)
J Natl Cancer Inst
, vol.55
, pp. 1265-1274
-
-
Carter, S.K.1
-
23
-
-
0028087601
-
Differential phosphorylation of human thymidine kinase in proliferating and M phase-arrested human cells
-
Chang ZF, Huang DY, Hsue NC. Differential phosphorylation of human thymidine kinase in proliferating and M phase-arrested human cells. J Biol Chem 1994;269:21249-54.
-
(1994)
J Biol Chem
, vol.269
, pp. 21249-21254
-
-
Chang, Z.F.1
Huang, D.Y.2
Hsue, N.C.3
-
24
-
-
23944450180
-
Control of dTTP pool size by anaphase promoting complex/cyclosome is essential for the maintenance of genetic stability
-
Ke PY, Kuo YY, Hu CM, Chang ZF. Control of dTTP pool size by anaphase promoting complex/cyclosome is essential for the maintenance of genetic stability. Genes Dev 2005;19:1920-33.
-
(2005)
Genes Dev
, vol.19
, pp. 1920-1933
-
-
Ke, P.Y.1
Kuo, Y.Y.2
Hu, C.M.3
Chang, Z.F.4
-
25
-
-
0025899234
-
Use of an aqueous soluble tetrazolium/formazan assay for cell growth assays in culture
-
Cory AH, Owen TC, Barltrop JA, Cory JG. Use of an aqueous soluble tetrazolium/formazan assay for cell growth assays in culture. Cancer Commun 1991;3:207-12.
-
(1991)
Cancer Commun
, vol.3
, pp. 207-212
-
-
Cory, A.H.1
Owen, T.C.2
Barltrop, J.A.3
Cory, J.G.4
-
26
-
-
0024402491
-
Enzymatic assay for deoxyribonucleoside triphosphates using synthetic oligonucleotides as template primers
-
Sherman PA, Fyfe JA. Enzymatic assay for deoxyribonucleoside triphosphates using synthetic oligonucleotides as template primers. Anal Biochem 1989;180:222-6.
-
(1989)
Anal Biochem
, vol.180
, pp. 222-226
-
-
Sherman, P.A.1
Fyfe, J.A.2
-
27
-
-
0343280013
-
A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage
-
Paull TT, Rogakou EP, Yamazaki V, Kirchgessner CU, Gellert M, Bonner WM. A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage. Curr Biol 2000;10:886-95.
-
(2000)
Curr Biol
, vol.10
, pp. 886-895
-
-
Paull, T.T.1
Rogakou, E.P.2
Yamazaki, V.3
Kirchgessner, C.U.4
Gellert, M.5
Bonner, W.M.6
-
28
-
-
13444273546
-
DNA repair: The importance of phosphorylating histone H2AX
-
Lowndes NF, Toh GW. DNA repair: the importance of phosphorylating histone H2AX. Curr Biol 2005;15:R99-102.
-
(2005)
Curr Biol
, vol.15
-
-
Lowndes, N.F.1
Toh, G.W.2
-
29
-
-
1242316160
-
Small interfering double-stranded RNAs as therapeutic molecules to restore chemosensitivity to thymidylate synthase inhibitor compounds
-
Schmitz JC, Chen TM, Chu E. Small interfering double-stranded RNAs as therapeutic molecules to restore chemosensitivity to thymidylate synthase inhibitor compounds. Cancer Res 2004;64:1431-5.
-
(2004)
Cancer Res
, vol.64
, pp. 1431-1435
-
-
Schmitz, J.C.1
Chen, T.M.2
Chu, E.3
-
30
-
-
0036570007
-
The role of thymidylate synthase induction in modulating p53-regulated gene expression in response to 5-fluorouracil and antifolates
-
Longley DB, Boyer J, Allen WL, et al. The role of thymidylate synthase induction in modulating p53-regulated gene expression in response to 5-fluorouracil and antifolates. Cancer Res 2002;62:2644-9.
-
(2002)
Cancer Res
, vol.62
, pp. 2644-2649
-
-
Longley, D.B.1
Boyer, J.2
Allen, W.L.3
-
31
-
-
0019205414
-
The effect of methotrexate on levels of dUTP in animal cells
-
Goulian M, Bleile B, Tseng BY. The effect of methotrexate on levels of dUTP in animal cells. J Biol Chem 1980;255:10630-7.
-
(1980)
J Biol Chem
, vol.255
, pp. 10630-10637
-
-
Goulian, M.1
Bleile, B.2
Tseng, B.Y.3
-
32
-
-
0141757494
-
Regulation and mechanisms of mammalian double-strand break repair
-
Valerie K, Povirk LF. Regulation and mechanisms of mammalian double-strand break repair. Oncogene 2003;22:5792-812.
-
(2003)
Oncogene
, vol.22
, pp. 5792-5812
-
-
Valerie, K.1
Povirk, L.F.2
-
33
-
-
0037365789
-
ATM and related protein kinases: Safe-guarding genome integrity
-
Shiloh Y. ATM and related protein kinases: safe-guarding genome integrity. Nat Rev Cancer 2003;3:155-68.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 155-168
-
-
Shiloh, Y.1
-
34
-
-
34447551681
-
Roles of ATM and NBS1 in chromatin structure modulation and DNA double-strand break repair
-
Berkovich E, Monnat RJ, Jr., Kastan MB. Roles of ATM and NBS1 in chromatin structure modulation and DNA double-strand break repair. Nat Cell Biol 2007;9:683-90.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 683-690
-
-
Berkovich, E.1
Monnat Jr., R.J.2
Kastan, M.B.3
|