Overexpression of RRM2 decreases thrombspondin-1 and increases VEGF production in human cancer cells in vitro and in vivo: Implication of RRM2 in angiogenesis

Molecular Cancer

Volumn 8, Issue , 2009, Pages

  Zhang, Keqiang ^a   Hu, Shuya ^a   Wu, Jun ^a   Chen, Linling ^a   Lu, Jianming ^a   Wang, Xiaochen ^a   Liu, Xiyong ^a   Zhou, Bingsen ^a   Yen, Yun ^a  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RIBONUCLEOTIDE REDUCTASE; RIBONUCLEOTIDE REDUCTASE SMALL SUBUNIT 2; SMALL INTERFERING RNA; THROMBOSPONDIN 1; UNCLASSIFIED DRUG; VASCULOTROPIN; CD31 ANTIGEN; RIBONUCLEOSIDE DIPHOSPHATE REDUCTASE; RIBONUCLEOTIDE REDUCTASE M2; VASCULOTROPIN A; VEGFA PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CARCINOGENESIS; CELL HYPOXIA; CELL MIGRATION; CELL PROLIFERATION; CELL STRAIN KB; CELL STRAIN LNCAP; CHEMOTAXIS; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; TUMOR; TUMOR GROWTH; TUMOR VASCULARIZATION; TUMOR XENOGRAFT; UPREGULATION; ANIMAL; DRUG SCREENING; IMMUNOHISTOCHEMISTRY; METABOLISM; NEOVASCULARIZATION (PATHOLOGY); TUMOR CELL LINE;

ANIMALS; ANTIGENS, CD31; CELL LINE, TUMOR; CELL PROLIFERATION; HUMANS; IMMUNOHISTOCHEMISTRY; MICE; NEOVASCULARIZATION, PATHOLOGIC; RIBONUCLEOSIDE DIPHOSPHATE REDUCTASE; RNA, SMALL INTERFERING; THROMBOSPONDIN 1; VASCULAR ENDOTHELIAL GROWTH FACTOR A; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 63849188689     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-8-11     Document Type: Article

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