Angiotensin-converting enzyme deletion allele is beneficial for the longevity of Europeans

Age

Volumn 34, Issue 3, 2012, Pages 583-595

  Zajc Petranović, Matea ^a   Škarić Jurić, Tatjana ^a   Smolej Narančić, Nina ^a   Tomas, Željka ^a   Krajačić, Petra ^a   Miličić, Jasna ^a   Barbalić, Maja ^b   Tomek Roksandić, Spomenka ^c  

^a INSTITUTE FOR ANTHROPOLOGICAL RESEARCH   (Croatia)

^b UNIVERSITY OF TEXAS   (United States)

^c UNIVERSITY OF ZAGREB   (Croatia)

Author keywords

ACE I D polymorphism; Aged; Aged 80 and over; Hypertension; Longevity; Meta analysis

Indexed keywords

CHOLESTEROL; DIPEPTIDYL CARBOXYPEPTIDASE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ACE GENE; AGE; AGED; ARTICLE; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CROATIA; DENMARK; DIASTOLIC BLOOD PRESSURE; DYSLIPIDEMIA; FEMALE; FINLAND; FRANCE; GENDER; GENE; GENE DELETION; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC DIFFERENCE; GENETIC HETEROGENEITY; GENETIC POLYMORPHISM; GENOTYPE; GENOTYPING TECHNIQUE; GERMANY; HUMAN; HYPERTENSION; ITALY; LONGEVITY; MALE; OBESITY; RUSSIAN FEDERATION; SLOVAKIA; SPAIN; SYSTOLIC BLOOD PRESSURE; TRIACYLGLYCEROL BLOOD LEVEL; UNITED KINGDOM;

AGED, 80 AND OVER; AGING; ALLELES; CARDIOVASCULAR DISEASES; CROATIA; DNA; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; FOLLOW-UP STUDIES; GENE DELETION; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; INCIDENCE; LONGEVITY; MALE; PEPTIDYL-DIPEPTIDASE A; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; RETROSPECTIVE STUDIES; RISK FACTORS; SURVIVAL RATE;

EID: 84863717047     PISSN: 01619152     EISSN: 15744647     Source Type: Journal    
DOI: 10.1007/s11357-011-9270-0     Document Type: Article

References (98)

1. Agerholm-Larsen B, Tybjaerg-Hansen A, Frikke-Schmidt R et al (1997) ACE gene polymorphism as a risk factor for ischemic cerebrovascular disease. Ann Intern Med 127:346-355 (Pubitemid 27362742)
2. Agerholm-Larsen B, Nordestgaard BG, Tybjaerg-Hansen A (2000) ACE gene polymorphism in cardiovascular disease: meta-analyses of small and large studies in whites. Arterioscler Thromb Vasc Biol 20:484-492 (Pubitemid 30086107)
3. Alía P, Mañá J, Capdevila O et al (2005) Association between ACE gene I/D polymorphism and clinical presentation and prognosis of sarcoidosis. Scand J Clin Lab Invest 65 (8):691-698
4. Alvarez R, Alvarez V, Lahoz CH et al (1999) Angiotensin converting enzyme and endothelial nitric oxide synthase DNA polymorphisms and late onset Alzheimer's disease. J Neurol Neurosurg Psychiatry 67:733-736
5. Arbustini E, Grasso M, Fasani R et al (1995) Angiotensin converting enzyme gene deletion allele is independently and strongly associated with coronary atherosclerosis and myocardial infarction. Br Heart J 74:584-591 (Pubitemid 26005489)
6. Arias-Vasquez A, Sayed-Tabatabaei FA, Schut AF et al (2005) Angiotensin converting enzyme gene, smoking and mortality in a population-based study. Eur J Clin Invest 35:444-449 (Pubitemid 40992774)
7. Barbalić M, Peričić M, Škarić- Jurić T, Smolej Narančić N (2004) ACE Alu insertion polymorphism in Croatia and its isolates. Coll Antropol 28:603-610 (Pubitemid 40115786)
8. Barbalić M, Škarić-Jurić T, Cambien F et al (2006) Gene polymorphisms of the renin-angiotensin system and early development of hypertension. Am J Hypertens 19 (8):837-842 (Pubitemid 44107688)
9. Bautista LE, Ardila ME, Gamarra G, Vargas CI, Arenas IA (2004) Angiotensin-converting enzyme gene polymorphism and risk of myocardial infarction in Colombia. Med Sci Monit 10(8):473-479
10. Benigni A, Cassis P, Remuzzi G (2010) Angiotensin II revisited: new roles in inflammation, immunology and aging. EMBO Mol Med 2:247-257
11. Bladbjerg EM, Andersen-Ranberg K, de Maat MP et al (1999) Longevity is independent of common variations in genes associated with cardiovascular risk. Thromb Haemost 82:1100-1105 (Pubitemid 29419726)
12. Blanche H, Cabanne L, Sahbatou M, Thomas G (2001) A study of French centenarians: are ACE and APOE associated with longevity? C R Acad Sci III 324:129-135 (Pubitemid 33130183)
13. Brewster UC, Perazella MA (2004) The renin-angiotensin- aldosterone system and the kidney: effects on kidney disease. Am J Med 116:263-272 (Pubitemid 38224234)
14. Busjahn A, Knoblauch J, Knoblauch M et al (1997) Angiotensin converting enzyme and angiotensinogen gene polymorphisms, plasma levels, and left ventricular size: a twin study. Hypertension 29:165-170 (Pubitemid 27074038)
15. Cambien F, Poirier O, Lecerf L et al (1992) Deletion polymorphism in the gene for angiotensin-convertingenzyme is a potent risk factor for myocardial infarction. Nature 359:641-644
16. Carlson KJ, Eisenstat SA, Ziporyn T (2004) The new Harvard guide to women's health. Harvard University, Boston, pp 41-42
17. Cheitlin MD, Zipes DP (2001) Cardiovascular disease in the elderly. In: Braunwald E, Zipes DP, Libby P (eds) Heart disease, 6th edn. WB Saunders, Philadelphia, p 2019
18. Clarke R, Emberson J, Fletcher A et al (2009) Life expectancy in relation to cardiovascular risk factors: 38 year follow-up of 19 000 men in the Whitehall study. BMJ 339:3513-3521
19. Companioni Nápoles O, Sautié Castellanos M, Leal L et al (2007) ACE I/D polymorphism study in a Cuban hypertensive population. Clin Chim Acta 378:112-116 (Pubitemid 46241069)
20. Corbo RM, Ulizzi L, Piombo L, Scacchi R (2008) Study on a possible effect of four longevity candidate genes (ACE, PON1, PPAR-c, and APOE) on human fertility. Biogerontology 9:317-323
21. Costerousse O, Allegrini J, Lopez M, Alhenc-Gelas F (1993) Angiotensin I converting enzyme in human circulating mononuclear cells: genetic polymorphism of expression in T-lymphocytes. Biochem J 290:33-40 (Pubitemid 23081197)
22. Crisan D, Carr J (2000) Angiotensin I-converting enzyme: genotype and disease associations. J Mol Diagn 2:105-115
23. Croatian Bureau of Statistics (1992) Census 1991. Croatian Bureau of Statistics, Zagreb
24. Dankova Z, Sivakova D, Luptakova L, Blazicek P (2009) Association of ACE (I/D) polymorphism with metabolic syndrome and hypertension in two ethnic groups in Slovakia. Anthropol Anz 67(3):305-316
25. de Cavanagh EM, Inserra F, Ferder M, Ferder L (2007) From mitochondria to disease: role of the renin-angiotensin system. Am J Nephrol 27:545-553 (Pubitemid 350014941)
26. Di Pasquale P, Cannizzaro S, Paterna S (2004) Does angiotensin-converting enzyme gene polymorphism affect blood pressure? Findings after 6 years of follow-up in healthy subjects. Eur J Heart Fail 6:11-16 (Pubitemid 38169599)
27. Dikmen M, Günes HV, Degirmenci I, Özdemir G, Basaran A (2006) Are the angiotensin-converting enzyme gene and activity risk factors for stroke? Arq Neuropsiquiatr 64 (2):212-216
28. Dolgikh MM, Voevoda MI, Malyutina SK (2001) Age change of ACE gene genotypes and alleles frequencies in urban population of West Siberia. First workshop on information technologies application to problems of biodiversity and dynamics of ecosystems in North Eurasia (WITA-2001), Book of abstracts
29. Egger M, Davey Smith G, Schneider M et al (1997) Bias in meta analysis detected by a simple, graphical test. BMJ 315(7109):629-634 (Pubitemid 27387172)
30. Ehlers MRW, Riordan JF (1989) Angiotensin-converting enzyme: new concepts concerning its biological role. Biochemistry 28:5311-5313
31. Fleming I (2006) Signaling by the angiotensin-converting enzyme. Circ Res 98:887-896
32. Freitas SRS, Cabello PH,Moura-Neto RS, Dolinsky LC, Bóia MN (2007) Combined Analysis of genetic and environmental factors on essential hypertension in a Brazilian rural population in the Amazon Region. Arq Bras Cardiol 88:393-397
33. Fuentes RM, Perola M, Nissinen A, Tuomilehto J (2002) ACE gene and physical activity, blood pressure and hypertension: a population study in Finland. J Appl Physiol 92:2508-2512 (Pubitemid 34666377)
34. Galinsky D, Tysoe C, Brayne CE et al (1997) Analysis of the apo E/apo C-I, angiotensin converting enzyme and methylenetetrahydrofolate reductase genes as candidates affecting human longevity. Atherosclerosis 129:177-183 (Pubitemid 27135318)
35. Garrib A, Zhou W, Sherwood R, Peters T (1998) Angiotensinconverting enzyme (ACE) gene polymorphism in patients with sarcoidosis. Biochem Soc Trans 26:137
36. Hadjadj S, Tarnow L, Forsblom C et al (2007) Association between angiotensin-converting enzyme gene polymorphisms and diabetic nephropathy: case-control, haplotype, and family-based study in three European populations. J Am Soc Nephrol 18:1284-1291 (Pubitemid 46536914)
37. Hernández Ortega E, Medina Fernández-Aceituno A, Rodríguez-Esparragón FJ et al (2002) The involvement of the renin-angiotension system gene polymorphisms in coronary heart disease. Rev Esp Cardiol 55:92-99 (Pubitemid 34232810)
38. Higaki J, Baba S, Katsuya T et al (2000) Deletion allele of angiotensin-converting enzyme gene in creases risk of essential hypertension in Japanese men: the Suita study. Circulation 101:2060-2065 (Pubitemid 30233169)
39. Higgins JP, Thompson SG,Deeks JJ, Altman DG (2003) Measuring inconsistency in meta-analyses. BMJ 327:557-560 (Pubitemid 37088507)
40. Huang S, Chen XH, Payne JR et al (2007) Haplotype of growth hormone and angiotensin I-converting enzyme genes, serum angiotensin I-converting enzyme and ventricular growth: pathway inference in pharmacogenetics. Pharmacogenet Genomics 17(4):291-294 (Pubitemid 46668053)
41. Islam MS, Lehtimäki T, Juonala M et al (2006) Polymorphism of the angiotensin-converting enzyme (ACE) and angiotesinogen (AGT) genes and their associations with blood pressure and carotid artery intima media thickness among healthy Finnish young adults-the cardiovascular risk in young Finns study. Atherosclerosis 188:316-322 (Pubitemid 44313922)
42. Jackson A, Brown K, Langdown J et al (2000) Effect of the angiotensin-converting enzyme gene deletion polymorphism on the risk of venous thromboembolism. Br J Haematol 111:562-564
43. Jeunemaitre X, Soubrier F, Kotelevtsev YV et al (1992a) Molecular basis of human hypertension: role of angiotensinogen. Cell 71:169-180
44. Jeunemaitre X, Lifton RP, Hunt SC, Williams RR, Lalouel JM (1992b) Absence of linkage between the angiotensin converting enzyme locus and human essential hypertension. Nat Genet 1:72-75
45. Jeunemaitre X, Inoue I, Williams C et al (1997) Haplotypes of angiotensinogen in essential hypertension. Am J Hum Genet 51:1448-1460 (Pubitemid 27258077)
46. Jiménez PM, Conde C, Casanegra A et al (2007) Association of ACE genotype and predominantly diastolic hypertension: a preliminary study. J Renin Angiotensin Aldosterone Syst 8:42-44 (Pubitemid 46779548)
47. Kalaydjieva L, Perez-Lezaun A, Angelicheva D et al (1999) A founder mutation in the GK1 gene is responsible for galactokinase deficiency in Roma (gypsies). Am J Hum Genet 65(5):1299-1307 (Pubitemid 30460380)
48. Keavney BD, Dudley CR, Stratton IMet al (1995)UKprospective diabetes study (UKPDS) 14: association of angiotensinconverting enzyme insertion/deletion polymorphism with myocardial infarction in NIDDM. Diabetologia 38(8):948-952
49. Kehoe PG, Russ C, McIlory S et al (1999) Variation in DCP1, encoding ACE, is associated with susceptibility to Alzheimer disease. Nat Genet 21:71-72 (Pubitemid 29036286)
50. Kitayama H, Maeshima Y, Takazawa Y et al (2006) Regulation of angiogenic factors in angiotensin II infusion model in association with tubulointerstitial injuries. Am J Hypertens 19:718-727 (Pubitemid 43928512)
51. Labreuche J, Deplanque D, Touboul PJ, Bruckert E, Amarenco P (2010) Association between change in plasma triglyceride levels and risk of stroke and carotid atherosclerosis: systematic review and meta-regression analysis. Atherosclerosis 212 (1):9-15
52. Lindpaintner K, Pfeffer MA, Kreutz R et al (1995) A prospective evaluation of an angiotensin converting enzyme gene polymorphism and the risk of ischemic heart disease. N Engl J Med 332:706-711
53. Lloyd-Jones DM, Evans JC, Levy D (2005) Hypertension in adults across the age spectrum: current outcomes and control in the ommunity. JAMA 294(4):466-472 (Pubitemid 41124179)
54. Lopez AD, Mathers CD, Ezzati M, Jamison DT, Murray CJ (2006) Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data. Lancet 367(9524):1747-1757 (Pubitemid 43767064)
55. Luft FC (1999) Bad genes, good people, association, linkage, longevity and the prevention of cardiovascular disease. Clin Exp Pharmacol Physiol 26(7):576-579 (Pubitemid 29309642)
56. Marre M, Jeunemaitre X, Gallois Y et al (1997) Contribution of genetic polymorphism in the renin-angiotensin system to the development of renal complications in insulindependent diabetes: Genetique de la Nephropathie Diabetique (GENEDIAB) study group. J Clin Invest 99 (7):1585-1595 (Pubitemid 27163809)
57. Martins D, Nelson K, Pan D, Tareen N, Norris K (2001) The effect of gender on age-related blood pressure changes and the prevalence of isolated systolic hypertension among older adults: data from NHANES III. J Gend Specif Med 4 (3):10-13, 20
58. McGeer EG, Singh EA (1992) Angiotensin-converting enzyme in cortical tissue in Alzheimer's and some other neurological diseases. Dementia 3:299-303 (Pubitemid 23011918)
59. Miller SA, Dykes DD, Polesky HF (1988) A simple salting out procedure for extracting DNA from nucleated cells. Nucleic Acids Res 16:1215
60. Miloserdova OV, Slominsky PA, Limborska SA (2001) Agedependent variation of the allele and genotype frequencies in insertion-deletion polymorphism for the angiotensinconverting enzyme gene. Genetika 38(1):87-89 (Pubitemid 135705056)
61. Ministry of Health of the Republic of Croatia (1995) First Croatian health project: final report. Ministry of Health, Zagreb
62. Miyama N, Hasegawa Y, Suzuki M et al (2007) Investigation of major genetic polymorphisms in the renin-angiotensin-aldosterone system in subjects with young-onset hypertension selected by a tar geted-screening system at university. Clin Exp Hypertens 29:61-67 (Pubitemid 46033108)
63. Mondry A, Loh M, Pengbo L, Zhu AL, Nagel M (2005) Polymorphisms of the insertion/deletion ACE and M235T
64. AGT genes and hypertension: surprising new findings and meta-analysis of data. BMC Nephrol 6:1-11
65. Myllykangas L, Polvikoski T, Sulkava R et al (2000) Cardiovascular risk factors and Alzheimer's disease: a genetic association study in a population aged 85 or over. Neurosci Lett 292:195-198
66. Nacmias B, Bagnoli S, Tedde A et al (2007) Angiotensin converting enzyme insertion/deletion polymorphism in sporadic and familial Alzheimers disease and longevity. Arch Gerontol Geriatr 45(2):201-206 (Pubitemid 47090190)
67. Nawaz SK, Hasnain S (2008) Pleiotropic effects of ACE polymorphism. Biochemia Med 19(1):36-49
68. Nazarov IB, Woods DR, Montgomery HE et al (2001) The angiotensin converting enzyme I/D polymorphism in Russian athletes. Eur J Hum Genet 9:797-801 (Pubitemid 33014594)
69. Panza F, Solfrizzi V, D'Introno A et al (2003) Angiotensin I converting enzyme (ACE) gene polymorphism in cente-narians: different allele frequencies between the North and South of Europe. Exp Gerontol 38:1015-1020 (Pubitemid 37040803)
70. Paolisso G, Tagliamonte MR, De Lucia D et al (2001) ACE gene polymorphism and insulin action in older subjects and healthy centenarians. J Am Geriatr Soc 49:610-614 (Pubitemid 32525033)
71. Papadopoulos KI, Melander O, Orho-Melander M et al (2000) Angiotensin converting enzyme (ACE) gene polymorphism in sarcoidosis in relation to associated autoimmune diseases. J Intern Med 247:71-77 (Pubitemid 30073166)
72. Paterna S, Di Pasquale P, D'Angelo A et al (2000) Angiotensinconverting enzyme gene deletion polymorphism determines an increase in frequency of migraine attacks in patients suffering from migraine without aura. Eur Neurol 43(3):133-136 (Pubitemid 30189532)
73. Petiti DB (1994) Meta-analysis decision analysis and costeffectiveness analysis, Oxford University Press
74. Platten M, Youssef S, Hur EM et al (2009) Blocking angiotensin-converting enzyme induces potent regulatory T cells and modulates TH1- and TH17-mediated autoimmunity. Proc Natl Acad Sci USA 106:14948-14953
75. Prospective Studies Collaboration (1995) Cholesterol, diastolic blood pressure and stroke: 13000 strokes in 450000 people in 45 prospective cohorts. Lancet 346:1647-1653
76. Pueyo ME, Gonzalez W, Nicoletti A et al (2000) Angiotensin stimulates endothelial vascular cell adhesion molecule-1 via nuclear factor-kappaB activation induced by intracellular oxidative stress. Arterioscler Thromb Vasc Biol 20:645-651 (Pubitemid 30151676)
77. Richard F, Fromentin-David I, Ricolfi F et al (2001) The angiotensin I converting enzyme gene as a susceptibility factor for dementia. Neurology 56:1593-1595 (Pubitemid 32532279)
78. Riera-Fortuny C, Real JT, Chaves FJ et al (2005) The relation between obesity, abdominal fat deposit and the angiotensin-converting enzyme gene I/D polymorphism and its association with coronary heart disease. Int J Obes Relat Metab Disord 29:78-84 (Pubitemid 40065468)
79. Rigat B, Hubert C, Alhenc-Gelas F et al (1990) An insertion/ deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels. J Clin Invest 86:1343-1346 (Pubitemid 20370444)
80. Samani NJ, O'Toole L, Martin D et al (1996) Insertion/deletion polymorphism in the angiotensin-converting enzyme gene and risk of and prognosis after myocardial infarction. J Am Coll Cardiol 28:338-344 (Pubitemid 26274325)
81. Sayed-Tabatabaei FA, Houwing-Duistermaat JJ, van Duijn CM, Witteman JC (2003) Angiotensin-converting enzyme gene polymorphism and carotid artery wall thickness: a metaanalysis. Stroke 34:1634-1639 (Pubitemid 36842616)
82. Schachter F, Faure-Delanef L, Guenot F et al (1994) Genetic associations with human longevity at the APOE and ACE loci. Nat Genet 6:29-32 (Pubitemid 24191909)
83. Schunkert H, Hense H-W, Holmer S-R et al (1994) Association between a deletion polymorphism of the angiotensin converting enzyme gene and left ventricular hypertrophy. N Engl J Med 330:1634-1638
84. Sharma P (1998) Meta-analysis of the ACE gene in ischaemic stroke. J Neurol Neurosurg Psychiatry 64:227-230 (Pubitemid 28159806)
85. Sharma P, Smith I, Maguire G, Stewart S, Shneerson J, Brown MJ (1997) Clinical value of ACE genotyping in diagnosis of sarcoidosis. Lancet 349:1602-1603 (Pubitemid 27229146)
86. Sivakova D, Lajdova A, Basistova Z, Cvicelova Z, Blazicek P (2009) ACE insertion/deletion polymorphism and its relationships to the components of metabolic syndrome in elderly Slovaks. Anthropol Anz 67(1):1-11
87. Škarić-Jurić T, Smolej Narančić N, Barbalić M, et al. (2006) Distribucija čimbenika rizika za kardiovaskularne bolesti u osoba starijih od 65 godina u Republici Hrvatskoj. In: Anic B, Tomek-Roksandic S (Eds.), 2nd Croatian gerontolological congress with international participation: book of abstracts. Liječnički vjesnik 128(1):64-65
88. Staessen JA, Wang JG, Ginocchio G et al (1997) The deletion/insertion polymorphism of the angiotensin converting enzyme gene and cardiovascular-renal risk. J Hypertens 15:1579-1592 (Pubitemid 28029652)
89. Suzuki Y, Ruiz-Ortega M, Lorenzo O et al (2003) Inflammation and angiotensin II. Int J Biochem Cell Biol 35:881-900 (Pubitemid 36379329)
90. Szadkowska A, Pietrzak I, Klich I et al (2006) Polymorphism I/ D of the angiotensin-converting enzyme gene and disturbance of blood pressure in type 1 diabetic children and adolescents. Przegl Lek 63:32-36
91. Vaisi-Raygani A, Ghaneialvar H, Rahimi Z et al (2010) The angiotensin converting enzyme D allele is an independent risk factor for early onset coronary artery disease. Clin Biochem 43:1189-1194
92. Vaitkevicius PV, Fleg JL, Engel JH et al (1993) Effects of age and aerobic capacity on arterial stiffness in healthy adults. Circulation 88:1456-1462 (Pubitemid 23296891)
93. Villar J, Flores C, Pérez-Méndez L et al (2008) Angiotensinconverting enzyme insertion/deletion polymorphism is not associated with susceptibility and outcome in sepsis and acute respiratory distress syndrome. Intensive Care Med 34:488-495 (Pubitemid 351623027)
94. Weiner JS, Lourie JA (1981) Practical human biology (International biological programme handbook No. 9). Academic, London
95. WHO (2000) Obesity: preventing and managing the global epidemic. Report of a WHO Consultation. WHO Technical Report Series 894. World Health Organization, Geneva
96. Xu X, Li J, Sheng W, Liu L (2008) Meta-analysis of genetic studies from journals published in China of ischemic stroke in the Han Chinese population. Cerebrovasc Dis 26(1):48-62 (Pubitemid 351931421)
97. Yin FCP, Spurgeon HA, Rakusan K, Weisfeldt ML, Lakatta EG (1982) Use of tibial length to quantify cardiac hypertrophy: application in the aging rat. Am J Physiol 243:941-947
98. Zhang YL, Zhou SX, Lei J, Zhang JM (2007) Association of angiotensin I-converting enzyme gene polymorphism with ACE and PAI-1 levels in Guangdong Chinese Han patients with essential hypertension. Nan Fang Yi Ke Da Xue Xue Bao 27(11):1681-1684