Analysis of the apo E/apo C-I, angiotensin converting enzyme and methylenetetrahydrofolate reductase genes as candidates affecting human longevity

Atherosclerosis

Volumn 129, Issue 2, 1997, Pages 177-183

  Galinsky, Daliah ^a   Tysoe, Carolyn ^a   Brayne, Carol E ^b   Easton, Douglas F ^b   Huppert, Felicia A ^c   Dening, Thomas R ^c   Paykel, Eugene S ^c   Rubinsztein, David C ^a  

^a ADDENBROOKE S HOSPITAL   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

ageing; angiotensin converting enzyme; Apo C I; Apo E; longevity; methylenetetrahydrofolate reductase

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); APOLIPOPROTEIN; DIPEPTIDYL CARBOXYPEPTIDASE;

ADOLESCENT; AGE; AGED; ARTICLE; CHILD; CORONARY ARTERY DISEASE; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; HEREDITY; HUMAN; LIPID METABOLISM; MALE; MORTALITY; NORMAL HUMAN; PRIORITY JOURNAL; RISK FACTOR;

ADOLESCENT; AGED; AGED, 80 AND OVER; ALLELES; APOLIPOPROTEIN C-I; APOLIPOPROTEINS C; APOLIPOPROTEINS E; CHILD; ENGLAND; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; LONGEVITY; MALE; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); OXIDOREDUCTASES ACTING ON CH-NH GROUP DONORS; PEPTIDYL-DIPEPTIDASE A;

EID: 0030985690     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9150(96)06027-3     Document Type: Article

References (25)

1. McGue M, Vaupel JW, Holm N, Harvald B. Longevity is moderately heritable in a sample of Danish twins born 1870-1898. J Gerontol 1993;48:B237-B244.
2. Rubinsztein DC. Apo E: a review of its roles in lipoprotein metabolism, neuronal growth and repair and as a risk factor for Alzheimer's disease. Psychol Med 1995;25:223-229.
3. Schachter F, Faure-Delanef L, Guenot F et al. Genetic associations with human longevity the APOE and ACE loci. Nat Genet 1994; 6:29-32.
4. Kervinen K, Savolainen MJ, Salokannel J et al. Apolipoprotein E and B polymorphisms - longevity factors assessed in nonagenarians. Atherosclerosis 1994;105;89-95.
5. Davignon J, Gregg RE, Sing CF. Apolipoprotein E polymorphism and atherosclerosis. Arteriosclerosis 1988;8:1-21.
6. Tiret L, Rigat L, Visvikis S et al. Evidence from combined segregation and linkage analysis that a variant of the angiotensin-converting enzyme (ACE) gene controls plasma ACE levels. Am J Hum Genet 1992;51;197-205.
7. Beohar N, Damaraju S, Prather A et al. Angiotensin-1 converting enzyme genotype DD is a risk factor for CAD. J Invest Med 1995;43:275-280.
8. Templeton AR. A cladistic analysis of phenotypic associations with haplotypes inferred from restriction endonuclease mapping or DNA sequencing. V. Analysis of case/control sampling designs: Alzheimer's disease and the apolipoprotein E locus. Genetics 1995;140:403-409.
9. Chartier-Harlin MC, Parfitt M, Legrain S et al. Apolipoprotein E, ε4 allele as a major risk factor for sporadic early and late-onset forms of Alzheimer's disease: analysis of the 19q13.2 chromosomal region. Hum Mol Genet 1995;3:569-574.
10. Rosenblatt DS. Inherited disorders of folate metabolism. In: Scriver CS, Beaudet AL, Sly WS, Valle D (eds). The Metabolic Basis of Inherited Disease. New York: McGraw-Hill, 1989, pp. 2049-2064.
11. Frosst P, Blom HJ, Milos R et al. A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Nat Genet 1995;10:111-113.
12. Paykel ES, Brayne C, Huppert FA et al. The incidence of dementia in the population over 75. Arch Gen Psychiatry 1994;51:325-332.
13. Heighway J, Hoban PR, Wyllie AH. SspI polymorphism in sequence encoding 3' untranslated region of the APC gene. Nucleic Acids Res 1991;19:6966.
14. Hixson JE, Vernier DT. Restriction isotyping of human apo E amplification and cleavage with Hha I. J Lipid Res 1990;31:545-548.
15. Nillesen WM, Smeets HJM, van Oost BA. Human apo C-I HpaI restriction site polymorphism revealed by the polymerase chain reaction. Nucleic Acids Res 1990;18:3428.
16. Rigat B, Hubert C, Corvol P, Soubrier F. PCR detection of the insertion deletion polymorphism of the human angiotensin converting enzyme gene (DCP1) (dipeptidyl carboxypeptidase). Nucleic Acids Res 1992;20:1433.
17. Frosst P, Blom HJ, Milos R et al. A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Nat Genet 1995;10:111-113.
18. Breslow NE, Day NE. Statistical Methods in Core Research, Vol I. The design and analysis of case-control studies. Lyon: IARC Scientific Publications no. 32, 1980.
19. Poirier J, Davignon J, Bouthillier D, Kogan S, Bertrand P, Gauthier, S. Apolipoprotein E polymorphism and Alzheimer's disease. Lancet 1993;342:697-699.
20. Payami H, Zareparsi S, Montee KR et al. Gender difference in apolipoprotein E-associated risk for familial Alzheimer disease: a possible clue to the higher incidence of Alzheimer disease in women. Am J Hum Genet 1996;58:803-811.
21. Reilly S, Ferrell RE, Sing CF. The gender-specific apolipoprotein E genotype influence on the distribution of plasma lipids and apolipoproteins in the population of Rochester, MN. III. Correlations and covariances. Am J Hum Genet 1994;55:1001-1018.
22. de Andrade M, Thandi I, Brown S, Gotto A Jr, Patsch W, Boerwinkle, E. Relationship of the apolipoprotein E polymorphism with carotid artery atherosclerosis. Am J Hum Genet 1995;56:1379-1390.
23. Ehlers MRW, Riordan JF. Angiotensin-converting enzyme. New concepts concerning its biological role. Biochemistry 1989;28:5311-5313.
24. Eisenlohr LC, Bacik I, Bennick JR, Bernstein K, Yewdell JW. Expression of a membrane protease enhances presentation of endogenous antigens to MHC class-1 restricted T lymphocytes. Cell 1992;71:963-972.
25. McGeer EG, Singh EA. Angiotensin-converting enzyme in cortical tissue in Alzheimer's and some other neurological diseases. Dementia 1992;3:299-303.