Association of ACE genotype and predominantly diastolic hypertension: A preliminary study

JRAAS - Journal of the Renin-Angiotensin-Aldosterone System

Volumn 8, Issue 1, 2007, Pages 42-44

  Jiménez, Pablo Martin ^a   Conde, Cecilia ^a   Casanegra, Ana ^b   Romero, Cesar ^a   Tabares, Aldo Hugo ^b   Orías, Marcelo ^c,d  

^a INSTITUTO DE INVESTIGACIÓN MÉDICA MERCEDES Y MARTÍN FERREYRA   (Argentina)

^b HOSPITAL PRIVADO   (Argentina)

^c Nephrology Section   (Argentina)

^d NONE   (Argentina)

Author keywords

Angiotensin II; Angiotensin converting enzyme; Genetic; Hypertension; Pulse pressure

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE;

ADULT; ARTICLE; CHI SQUARE TEST; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DIASTOLIC HYPERTENSION; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETIC VARIABILITY; GENOTYPE; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PULSE PRESSURE; SYSTOLIC BLOOD PRESSURE;

ADULT; AGED; BLOOD PRESSURE; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; HYPERTENSION; MALE; MIDDLE AGED; PEPTIDYL-DIPEPTIDASE A; PHENOTYPE; PILOT PROJECTS; POLYMORPHISM, GENETIC;

EID: 34249032091     PISSN: 14703203     EISSN: None     Source Type: Journal    
DOI: 10.3317/jraas.2007.006     Document Type: Article

References (19)

1. Lifton RP, Gharavi AG, Geller DS. Molecular mechanisms of human hypertension. Cell 2001;104:545-56.
2. SHEP, Cooperative, Research, Group. Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension: final results of the Systolic Hypertension in the Elderly Program (SHEP). JAMA 1991;265:3255-64.
3. Staessen J, Fagard R, Thijs L et al. Randomised double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension: the Systolic Hypertension in Europe (Syst-Eur) Trial Investigators. Lancet 1997;350:757-64.
4. Hozawa A, Ohkubo T, Nagai K et al. Prognosis of isolated systolic and isolated diastolic hypertension as assessed by self-measurement of blood pressure at home. The Ohasama study. Arch Intern Med 2000; 160:3301-06.
5. Galarza C, Alfie J, Waisman G et al. Diastolic pressure underestimates age-related hemodynamic impairment. Hypertension 1997;30:809-16.
6. Owens P, Lyons S, O Brien E. Ambulatory blood pressure monitoring in the hypertensive population: patterns and prevalence of hypertensive subforms. J Hypertens 1998;16:1735-43.
7. Soubrier F, Alhenc-Gelas F, Hubert C et al. Two putative active centers in human angiotensin I-converting enzyme revealed by molecular cloning. PNAS 1988;85:9386-90.
8. Rigat B, Hubert C, Alhenc-Gelas F, Cambien F, Corvol P, Soubrier F. An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels. J Clin Invest 1990;86:1343-6.
9. Jeunemaitre X, Lifton R, Hunt S, Williums R, Lalouel J. Absence of linkage between the angiotensin converting enzyme locus and human essential hypertension. Nat Genet 1992;1:72-5.
10. Staessen J, Wang J, Ginocchio G et al. The deletion/insertion polymorphism of the angiotensin converting enzyme gene and cardiovascular-renal risk. J Hypertens 1997;15:1579-92.
11. Mostafa Zaman M, Yoshiike N, Date C et al. Angiotensin converting enzyme genetic polymorphism is not associated with hypertension in a cross-sectional sample of a Japanese population: The Shibata Study. J Hypertens 2001;19:47-53.
12. Tiret L, Rigat B, Visvikis S et al. Evidence, from combined segregation and linkage analysis, that a variant of the angiotensin-converting enzyme (ACE) gene controls plasma ACE levels. Am J Hum Genet 1992;51:197-205.
13. Schillaci G, Verdecchia P, Borgioni C, Ciucci A, Porcellati C. Predictors of diurnal blood pressure changes in 2042 subjects with essential hypertension. J Hypertens 1996;14:1167-73.
14. Ueda S, Heeley R, Lees K, Elliott H, Connell J. Mistyping of the human angiotensin-converting enzyme gene polymorphism: frequency, causes and possible methods to avoid errors in typing. J Mol Endocrinol 1996;17:27-30.
15. Safar M, Laurent S, Safavian A, Pannier B, London G. Pulse pressure in sustained essential hypertension: a haemodynamic study. J Hypertens 1987;5:213-18.
16. Segers P, Stergiopulos N, Westerhof N. Quantification of the contribution of cardiac and arterial remodeling to hypertension. Hypertension 2000;36:760-5.
17. Castellano M. Diogenes in the 2000s: searching for hypertension genes. J Hypertens 2004;22:1081-3.
18. Chobanian A, Bakris G, Black H et al. The seventh report of the joint National Committee on prevention, detection, evaluation and treatment of high blood pressure. The JNC 7 report. JAMA 2003; 289:2560-72.
19. Franklin SS, Pio JR, Wong ND et al. Predictors of new-onset diastolic and systolic hypertension: The Framingham Heart Study. Circulation2005;111:1121-7.