Angiotensin converting enzyme insertion/deletion polymorphism in sporadic and familial Alzheimer's disease and longevity

Archives of Gerontology and Geriatrics

Volumn 45, Issue 2, 2007, Pages 201-206

  Nacmias, Benedetta ^a   Bagnoli, Silvia ^a   Tedde, Andrea ^a   Cellini, Elena ^a   Bessi, Valentina ^a   Guarnieri, Biancamaria ^b   Ortensi, Luigi ^b   Piacentini, Silvia ^a   Bracco, Laura ^a   Sorbi, Sandro ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b Casa di Cura Villa Serena   (Italy)

Author keywords

ACE; Alzheimer's disease; Apolipoprotein E; Gene polymorphism; Longevity and ACE

Indexed keywords

APOLIPOPROTEIN E; DIPEPTIDYL CARBOXYPEPTIDASE;

AGED; ALZHEIMER DISEASE; ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; FAMILIAL DISEASE; FEMALE; GENE DELETION; GENE FREQUENCY; GENE INSERTION; GENOTYPE; GERIATRIC PATIENT; HUMAN; ITALY; LONGEVITY; MAJOR CLINICAL STUDY; MALE; OUTPATIENT; PRIORITY JOURNAL;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; APOLIPOPROTEIN E4; CASE-CONTROL STUDIES; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; ITALY; LONGEVITY; MALE; MIDDLE AGED; MUTATION; PEPTIDYL-DIPEPTIDASE A; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; SEQUENCE DELETION;

EID: 34447648933     PISSN: 01674943     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.archger.2006.10.011     Document Type: Article

References (17)

1. APA (American Psychiatric Association), 1994. Diagnostic and Statistical Manual of Mental Disorders. 4th ed., (DSM-IV). American Psychiatric Publishing, APA Press, Washington DC.
2. Choi Y.H., Kim J.H., Kim D.K., Kim J.W., Kim D.K., Lee M.S., Kim C.H., and Park S.C. Distributions of ACE and APOE polymorphisms and their relations with dementia status in Korean centenarians. J. Gerontol. A, Biol. Sci. Med. Sci. 58 (2003) 225-226
3. The Dementia Study Group of the Italian Neurological Society. Guidelines for the diagnosis of dementia and Alzheimer's disease. Ital. J. Neurol. Sci. 21 (2000) 187-194
4. Elkins J.S., Douglas V.C., and Johnston S.C. Alzheimer disease risk and genetic variation in ACE: a meta-analysis. Neurology 62 (2004) 363-368
5. Hemming M.L., and Selkoe D.J. Amyloid beta-protein is degraded by cellular angiotensin-converting enzyme (ACE) and elevated by an ACE inhibitor. J. Biol. Chem. 280 (2005) 37644-37650
6. Kehoe P.G., Russ C., McIlory S., Williams H., Holmans P., Holmes C., Liolitsa D., Vahidassr D., Powell J., McGleenon B., Liddell M., Plomin R., Dynan K., Williams N., Neal J., Cairns N.J., Wilcock G., Passmore P., Lovestone S., Williams J., and Owen M.J. Variation in DCP1, encoding ACE, is associated with susceptibility to Alzheimer disease. Nat. Genet. 21 (1999) 71-72
7. Kolsch H., Jessen F., Freymann N., Kreis M., Hentschel F., Maier W., and Heun R. ACE I/D polymorphism is a risk factor of Alzheimer's disease but not of vascular dementia. Neurosci. Lett. 377 (2005) 37-39
8. Kritchevsky S.B., Nicklas B.J., Visser M., Simonsick E.M., Newman A.B., Harris T.B., Lange E.M., Penninx B.W., Goodpaster B.H., Satterfield S., Colbert L.H., Rubin M., and Pahor S.M. Angiotensin-converting enzyme insertion/deletion genotype, exercise, and physical decline. J. Am. Med. Assoc. 294 (2005) 691-698
9. Lehmann D.J., Cortina-Borja M., Warden D.R., Smith A.D., Sleegers K., Prince J.A., Van Duijn C.M., and Kehoe P.G. Large meta-analysis establishes the ACE insertion-deletion polymorphism as a marker of Alzheimer's disease. Am. J. Epidemiol. 162 (2005) 305-317
10. Panza F., Solfrizzi V., D'Introno A., Colacicco A.M., Capurso C., Kehoe P.G., and Capurso A. Angiotensin I converting enzyme (ACE) gene polymorphism in centenarians: different allele frequencies between the North and South of Europe. Exp. Gerontol. 38 (2003) 1015-1020
11. Rigat B., Hubert C., Corvol P., and Soubrier F. PCR detection of the insertion/deletion polymor-phism of the human angiotensin converting enzyme gene (DCP1) (dipeptidyl carboxypeptidase 1). Nucleic. Acids Res. 20 (1992) 1433
12. Schachter F., Faure-Delanef L., Guenot F., Rouger H., Froguel P., Lesueur-Ginot L., and Cohen D. Genetic association with human longevity with the APOE and ACE loci. Nat. Genet. 6 (1994) 429-432
13. Sleegers K., Den Heijer T., Van Dijk E.J., Hofman A., Bertoli-Avella A.M., Koudstaal P.J., Breteler M.M., and Van Duijn C.M. ACE gene is associated with Alzheimer's disease and atrophy of hippocampus and amygdale. Neurobiol. Aging 26 (2005) 1153-1159
14. Sorbi S., Nacmias B., Forleo P., Latorraca S., Gobbini I., Bracco L., Piacentini S., and Amaducci L. ApoE allele frequencies in Italian sporadic and familial Alzheimer's disease. Neurosci. Lett. 177 (1994) 100-102
15. Strittmatter W.J., and Roses A.D. Apolipoprotein E and Alzheimer disease. Proc. Natl. Acad. Sci. U.S.A. 92 (1995) 4725-4727
16. Tanzi R.E., and Bertram L. Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective. Cell 120 (2005) 545-555
17. Zhang J.W., Li X.Q., Zhang X., Chen D., Zhao H.L., Wu Y.N., and Qu Q.M. Association between angiotensin-converting enzyme gene polymorphism and Alzheimer's disease in a Chinese population. Dement. Geriatr. Cogn. Disorder. 20 (2005) 52-56