Biophysical properties of Nav1.8/Nav1.2 chimeras and inhibition by μo-conotoxin MrVIB

British Journal of Pharmacology

Volumn 166, Issue 7, 2012, Pages 2148-2160

  Knapp, O ^a   Nevin, S T ^a,b   Yasuda, T ^a   Lawrence, N ^b   Lewis, R J ^b   Adams, D J ^a  

^a RMIT UNIVERSITY   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

O conotoxin MrVIB; chimera; electrophysiology; heterologous expression; Na v1.2; Nav1.8; tetrodotoxin; voltage gated sodium channels; Xenopus oocytes

Indexed keywords

CONOTOXIN; MU O CONOTOXIN MRVIA; MU O CONOTOXIN MRVIB; SODIUM CHANNEL NAV1.2; SODIUM CHANNEL NAV1.8; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING SITE; BIOPHYSICS; CONTROLLED STUDY; CONUS MARMOREUS; DRUG ACTIVITY; ELECTROPHYSIOLOGY; ENZYME INHIBITION; MEMBRANE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN INTERACTION; SNAIL; SODIUM CURRENT; XENOPUS;

ANIMALS; CELLS, CULTURED; CONOTOXINS; FEMALE; NAV1.2 VOLTAGE-GATED SODIUM CHANNEL; NAV1.8 VOLTAGE-GATED SODIUM CHANNEL; OOCYTES; PROTEIN SUBUNITS; TETRODOTOXIN; XENOPUS LAEVIS;

EID: 84863682656     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2012.01955.x     Document Type: Article

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