Structures of μO-conotoxins from Conus marmoreus: Inhibitors of tetrodotoxin (TTX)-sensitive and TTX-resistant sodium channels in mammalian sensory neurons

Journal of Biological Chemistry

Volumn 279, Issue 24, 2004, Pages 25774-25782

  Daly, Norelle L ^a   Ekberg, Jenny A ^a   Thomas, Linda ^a   Adams, David J ^a   Lewis, Richard J ^a   Craik, David J ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL BONDS; ELECTRIC POTENTIAL; ENZYME INHIBITION; NEUROLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

CONOTOXINS; STRUCTURAL INFORMATION;

BIOCHEMISTRY;

ACETONITRILE; CONOTOXIN; CYSTEINE; CYSTINE; DELTA CONOTOXIN; MUO CONOTOXIN; OMEGA CONOTOXIN; SOLVENT; TETRODOTOXIN; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL; VOLTAGE GATED SODIUM CHANNEL; WATER; MUO CONOTOXIN MRVIA; MUO CONOTOXIN MRVIB; MUO-CONOTOXIN MRVIA; MUO-CONOTOXIN MRVIB; SODIUM CHANNEL; SODIUM CHANNEL BLOCKING AGENT;

AQUEOUS SOLUTION; ARTICLE; BETA SHEET; CONTROLLED STUDY; CONUS MARMOREUS; DISULFIDE BOND; HYDROPHOBICITY; MOLLUSC; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; RAT; SENSORY NERVE CELL; SODIUM CURRENT; SOLUBILIZATION; SPINAL GANGLION; STRUCTURE ANALYSIS; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; DRUG EFFECT; MOLECULAR GENETICS; NUCLEAR MAGNETIC RESONANCE; PHYSIOLOGY; PROTEIN SECONDARY STRUCTURE;

CONUS MARMOREUS; INVERTEBRATA; MAMMALIA; MOLLUSCA;

AMINO ACID SEQUENCE; ANIMALS; CONOTOXINS; GANGLIA, SPINAL; MOLECULAR SEQUENCE DATA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN STRUCTURE, SECONDARY; RATS; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS; TETRODOTOXIN;

EID: 2942554865     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M313002200     Document Type: Article

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