Vaccinia-related kinase 1 (VRK1) is an upstream nucleosomal kinase required for the assembly of 53BP1 foci in response to ionizing radiation-induced DNA damage

Journal of Biological Chemistry

Volumn 287, Issue 28, 2012, Pages 23757-23768

  Sanz Garciá, Marta ^a   Monsalve, Diana M ^a,b   Sevilla, Ana ^a   Lazo, Pedro A ^a,b  

^a CSIC   (Spain)

^b HOSPITAL UNIVERSITARIO DE SALAMANCA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ATAXIA-TELANGIECTASIA MUTATED; CELLULAR RESPONSE; DNA DAMAGE RESPONSE; DNA DAMAGES; DNA DOUBLE STRAND BREAKS; DNA-DEPENDENT PROTEIN KINASE; MAMMALIAN DNA; MOLECULAR COMPONENTS; NUMBER AND SIZE; PROTEIN COMPLEXES; RADIATION-INDUCED; RESTING CELLS; SCAFFOLD PROTEIN; SERUM-STARVED CELLS;

CHEMICAL ACTIVATION; ENZYMES; INTERNET PROTOCOLS; IONIZING RADIATION; MAMMALS; PHOSPHORYLATION; PROTEINS; RADIATION SHIELDING; SCAFFOLDS (BIOLOGY);

DNA;

ATM PROTEIN; CHECKPOINT KINASE 2; DNA DEPENDENT PROTEIN KINASE; PHOSPHOTRANSFERASE; PROTEIN 53BP1; PROTEIN P53; SCAFFOLD PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; VACCINIA RELATED KINASE 1;

ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DOUBLE STRANDED DNA BREAK; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IONIZING RADIATION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN PHOSPHORYLATION;

BLOTTING, WESTERN; CELL CYCLE PROTEINS; CELL LINE, TUMOR; DNA DAMAGE; DNA-BINDING PROTEINS; HEK293 CELLS; HUMANS; IMMUNOPRECIPITATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICROSCOPY, CONFOCAL; MUTATION; NUCLEOSOMES; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; RADIATION, IONIZING; RNA INTERFERENCE; TUMOR SUPPRESSOR PROTEINS;

ATAXIA TELANGIECTASIA; MAMMALIA;

EID: 84863623166     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.353102     Document Type: Article

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