Downregulation of vrk1 by p53 in response to DNA damage is mediated by the autophagic pathway

PLoS ONE

Volumn 6, Issue 2, 2011, Pages

  Valbuena, Alberto ^a   Castro Obregón, Susana ^b   Lazo, Pedro A ^a  

^a UNIVERSITY OF SALAMANCA   (Spain)

^b INSTITUTO DE BIOTECNOLOGÍA   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

BECLIN 1; CELL PROTEIN; DOXORUBICIN; ETOPOSIDE; PROTEASOME; PROTEIN LC3; PROTEIN MDM2; PROTEIN P53; PROTEIN P62; PROTEIN SERINE THREONINE KINASE; UNCLASSIFIED DRUG; VACCINIA RELATED KINASE 1; ANTINEOPLASTIC AGENT; DRAM PROTEIN, HUMAN; PROTEIN; SIGNAL PEPTIDE; SMALL INTERFERING RNA; VRK1 PROTEIN, HUMAN;

ARTICLE; AUTOPHAGY; CONTROLLED STUDY; DNA DAMAGE; DOWN REGULATION; DRAM GENE; GENE; GENE INDUCTION; GENE LOCATION; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; INFRARED RADIATION; LYSOSOME; MUTANT; NUCLEOTIDE SEQUENCE; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; ULTRAVIOLET RADIATION; WILD TYPE; BIOLOGICAL MODEL; CELL CULTURE; CELL CYCLE; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHYSIOLOGY; RADIATION EXPOSURE; SIGNAL TRANSDUCTION;

ANTINEOPLASTIC AGENTS; AUTOPHAGY; CELL CYCLE; CELLS, CULTURED; DNA DAMAGE; DOWN-REGULATION; DOXORUBICIN; ETOPOSIDE; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; HUMANS; INFRARED RAYS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MODELS, BIOLOGICAL; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53; ULTRAVIOLET RAYS;

EID: 79952215577     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0017320     Document Type: Article

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