Discovery of novel glucose-regulated proteins in isolated human pancreatic islets using LC-MS/MS-based proteomics

Journal of Proteome Research

Volumn 11, Issue 7, 2012, Pages 3520-3532

  Schrimpe Rutledge, Alexandra C ^a   Fontès, Ghislaine ^b   Gritsenko, Marina A ^a   Norbeck, Angela D ^a   Anderson, David J ^a   Waters, Katrina M ^a   Adkins, Joshua N ^a   Smith, Richard D ^a   Poitout, Vincent ^b,c   Metz, Thomas O ^a  

^a PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

^b CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

glucose; human; LC MS MS; mass spectrometry; pancreatic islet; proteomics; type 2 diabetes

Indexed keywords

BAX INHIBITOR 1; GLUCOSE; GLUCOSE REGULATED PROTEIN; NEURON NAVIGATOR 1; NUCLEAR RNA; PHOSPHOLIPASE C BETA4; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN INHIBITOR; RETINOBLASTOMA BINDING PROTEIN 6; SYNAPTOTAGMIN 17; UNCLASSIFIED DRUG;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; PANCREAS ISLET; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEOMICS; RNA SPLICING; UPREGULATION; WESTERN BLOTTING;

ACETYLTRANSFERASES; CHROMATOGRAPHY, ION EXCHANGE; CHROMATOGRAPHY, REVERSE-PHASE; CLUSTER ANALYSIS; COENZYME A LIGASES; DEAD-BOX RNA HELICASES; GENE EXPRESSION REGULATION; GLUCOSE; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; ISLETS OF LANGERHANS; MITOCHONDRIA; PEPTIDE MAPPING; PHOSPHOLIPASE C BETA; PROTEOME; PROTEOMICS; RIBONUCLEASE III; TANDEM MASS SPECTROMETRY; TISSUE CULTURE TECHNIQUES;

EID: 84863620710     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr3002996     Document Type: Article

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