Activating mitochondrial regulator PGC-1α expression by astrocytic NGF is a therapeutic strategy for Huntington's disease

Neuropharmacology

Volumn 63, Issue 4, 2012, Pages 719-732

  Chen, Li Wen ^a   Horng, Lin Yea ^a   Wu, Chia Ling ^a   Sung, Hui Ching ^a   Wu, Rong Tsun ^a  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

3 Nitropropionic acid; Astrocytes; Nerve growth factor; Neuroregeneration; Peroxisome proliferator activated receptor coactivator 1

Indexed keywords

3 NITROPROPIONIC ACID; GANODERIC ACID C2; GANODERMA LUCIDUM EXTRACT; NERVE GROWTH FACTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; SMALL INTERFERING RNA; SUCCINATE DEHYDROGENASE; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; BLOOD BRAIN BARRIER; CELL LOSS; CONTROLLED STUDY; CULTURE MEDIUM; DRUG DOSE COMPARISON; DRUG PENETRATION; DRUG STRUCTURE; DRUG TARGETING; ENZYME ACTIVITY; HUNTINGTON CHOREA; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MOUSE; NERVE CELL; NERVE CELL DEGENERATION; NEUROPROTECTION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; SENSORIMOTOR FUNCTION; SIGNAL TRANSDUCTION;

ANIMALS; ANIMALS, NEWBORN; ASTROCYTES; CELLS, CULTURED; CORPUS STRIATUM; DISEASE MODELS, ANIMAL; DRUGS, CHINESE HERBAL; GLIOSIS; HUNTINGTON DISEASE; MALE; MICE; MICE, INBRED C57BL; MITOCHONDRIA; NERVE DEGENERATION; NERVE GROWTH FACTOR; PC12 CELLS; RATS; REISHI; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS; TRITERPENES; UP-REGULATION;

EID: 84863620242     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2012.05.019     Document Type: Article

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