TGFβ intercepts nuclear glycogen synthase kinase 3β to inhibit PDGF-induced DNA synthesis in mesangial cells

FEBS Letters

Volumn 581, Issue 27, 2007, Pages 5259-5267

  Das, Falguni ^a   Mahimainathan, Lenin ^a   Ghosh Choudhury, Nandini ^b,c   Venkatesan, Balachandar ^a   Kasinath, Balakuntalam S ^a,c   Abboud, Hanna E ^a,c   Ghosh Choudhury, Goutam ^a,c,d  

^a University of Texas Health Science Center   (United States)

^b Department of Pathology ^*  (United States)

^c SOUTH TEXAS VETERANS HEALTH CARE SYSTEM   (United States)

^d Education and Clinical Center   (United States)

Author keywords

Akt kinase; CDK2; Cyclin D1; Glomerulonephritis; GSK3 ; Mitogenesis

Indexed keywords

CYCLIN D1; CYCLIN DEPENDENT KINASE 2; CYCLIN E; DNA; GLYCOGEN SYNTHASE KINASE 3BETA; MUTANT PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PLATELET DERIVED GROWTH FACTOR; PROTEIN KINASE B; SERINE; TRANSFORMING GROWTH FACTOR BETA; TYROSINE; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; PLATELET DERIVED GROWTH FACTOR RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CELL PROLIFERATION; CONTROLLED STUDY; DNA SYNTHESIS; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME PHOSPHORYLATION; GLOMERULONEPHRITIS; HUMAN; HUMAN CELL; MESANGIUM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; BIOSYNTHESIS; CELL NUCLEUS; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; PHOSPHORYLATION;

ANIMALS; CELL NUCLEUS; CYCLIN D1; CYCLIN-DEPENDENT KINASE 2; DNA; GLYCOGEN SYNTHASE KINASE 3; HUMANS; MESANGIAL CELLS; PHOSPHORYLATION; PLATELET-DERIVED GROWTH FACTOR; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR; TRANSFORMING GROWTH FACTOR BETA;

EID: 35548958658     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2007.10.014     Document Type: Article

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