The spin trap 5,5-dimethyl-1-pyrroline N-oxide inhibits lipopolysaccharide-induced inflammatory response in RAW 264.7 cells

Life Sciences

Volumn 90, Issue 11-12, 2012, Pages 432-439

  Zhai, Zili ^a   Gomez Mejiba, Sandra E ^a,b   Zhu, Hua ^a   Lupu, Florea ^a   Ramirez, Dario C ^a,b  

^a OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

^b Laboratory of Experimental and Therapeutic Medicine   (Argentina)

Author keywords

5,5 dimethyl 1 pyrroline N oxide; Free radical; Inflammation; Lipopolysaccharide; Macrophage; NF B

Indexed keywords

5,5 DIMETHYL 1 PYRROLINE 1 OXIDE; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR RELA;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; ENZYME PHOSPHORYLATION; INFLAMMATION; MACROPHAGE; PROTEIN EXPRESSION; PROTEIN TRANSPORT;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BLOTTING, WESTERN; CELL LINE, TUMOR; CYCLIC N-OXIDES; INFLAMMATION; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NITRIC OXIDE SYNTHASE TYPE II; NITRITES; REACTIVE OXYGEN SPECIES; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPIN LABELS;

EID: 84863393602     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2011.12.018     Document Type: Article

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