-
1
-
-
62549152705
-
Colorectal cancer, one entity or three
-
Li, F. Y. and Lai, M. D. (2009) Colorectal cancer, one entity or three. J. Zhejiang Univ. Sci. B., 10, 219-229.
-
(2009)
J. Zhejiang Univ. Sci. B.
, vol.10
, pp. 219-229
-
-
Li, F.Y.1
Lai, M.D.2
-
2
-
-
78049485263
-
Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
-
Ferlay, J., Shin, H. R., Bray, F., Forman, D., Mathers, C. and Parkin, D. M. (2010) Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int. J. Cancer, 127, 2893-2917.
-
(2010)
Int. J. Cancer
, vol.127
, pp. 2893-2917
-
-
Ferlay, J.1
Shin, H.R.2
Bray, F.3
Forman, D.4
Mathers, C.5
Parkin, D.M.6
-
3
-
-
33845336152
-
The balance between heritable and environmental aetiology of human disease
-
DOI 10.1038/nrg2009, PII NRG2009
-
Hemminki, K., Lorenzo Bermejo, J. and Forsti, A. (2006) The balance between heritable and environmental aetiology of human disease. Nat. Rev. Genet., 7, 958-965. (Pubitemid 44871399)
-
(2006)
Nature Reviews Genetics
, vol.7
, Issue.12
, pp. 958-965
-
-
Hemminki, K.1
Lorenzo Bermejo, J.2
Forsti, A.3
-
4
-
-
62349092262
-
Red meat and poultry intake, polymorphisms in the nucleotide excision repair and mismatch repair pathways and colorectal cancer risk
-
Joshi, A. D., Corral, R., Siegmund, K. D. et al. (2009) Red meat and poultry intake, polymorphisms in the nucleotide excision repair and mismatch repair pathways and colorectal cancer risk. Carcinogenesis, 30, 472-479.
-
(2009)
Carcinogenesis
, vol.30
, pp. 472-479
-
-
Joshi, A.D.1
Corral, R.2
Siegmund, K.D.3
-
5
-
-
77951630296
-
Primary prevention ofcolorectal cancer
-
e2010
-
Chan, A. T. and Giovannucci, E. L. (2010) Primary prevention ofcolorectal cancer. Gastroenterology, 138, 2029-2043. e2010.
-
(2010)
Gastroenterology
, vol.138
, pp. 2029-2043
-
-
Chan, A.T.1
Giovannucci, E.L.2
-
6
-
-
76049128595
-
Estimates of cancer incidence and mortality in Europe in 2008
-
Ferlay, J., Parkin, D. M. and Steliarova-Foucher, E. (2010) Estimates of cancer incidence and mortality in Europe in 2008. Eur. J. Cancer, 46, 765-781.
-
(2010)
Eur. J. Cancer
, vol.46
, pp. 765-781
-
-
Ferlay, J.1
Parkin, D.M.2
Steliarova-Foucher, E.3
-
7
-
-
0025312728
-
A genetic model for colorectal tumorigenesis
-
Fearon, E. R. and Vogelstein, B. (1990) A genetic model for colorectal tumorigenesis. Cell, 61, 759-767.
-
(1990)
Cell
, vol.61
, pp. 759-767
-
-
Fearon, E.R.1
Vogelstein, B.2
-
8
-
-
78651241644
-
Colorectal cancer molecular biology moves into clinical practice
-
Pritchard, C. C. and Grady, W. M. Colorectal cancer molecular biology moves into clinical practice. Gut, 60, 116-129.
-
Gut
, vol.60
, pp. 116-129
-
-
Pritchard, C.C.1
Grady, W.M.2
-
9
-
-
77953105174
-
New strategies for treatment of KRAS mutant metastatic colorectal cancer
-
Prenen, H., Tejpar, S. and Van Cutsem, E. (2010) New strategies for treatment of KRAS mutant metastatic colorectal cancer. Clin. Cancer Res., 16, 2921-2926.
-
(2010)
Clin. Cancer Res.
, vol.16
, pp. 2921-2926
-
-
Prenen, H.1
Tejpar, S.2
Van Cutsem, E.3
-
10
-
-
4944240144
-
Genetic predisposition to colorectal cancer
-
DOI 10.1038/nrc1453
-
de la Chapelle, A. (2004) Genetic predisposition to colorectal cancer. Nat. Rev. Cancer, 4, 769-780. (Pubitemid 39331149)
-
(2004)
Nature Reviews Cancer
, vol.4
, Issue.10
, pp. 769-780
-
-
De La Chapelle, A.1
-
11
-
-
0032555020
-
Incidence of hereditary nonpolyposis colorectal cancer and the feasibility of molecular screening for the disease
-
DOI 10.1056/NEJM199805213382101
-
Aaltonen, L. A., Salovaara, R., Kristo, P. et al. (1998) Incidence of hereditary nonpolyposis colorectal cancer and the feasibility of molecular screening for the disease. N. Engl. J. Med., 338, 1481-1487. (Pubitemid 28226275)
-
(1998)
New England Journal of Medicine
, vol.338
, Issue.21
, pp. 1481-1487
-
-
Aaltonen, L.A.1
Salovaara, R.2
Kristo, P.3
Canzian, F.4
Hemminki, A.5
Peltomaki, P.6
Chadwick, R.B.7
Kaariainen, H.8
Eskelinen, M.9
Jarvinen, H.10
Mecklin, J.-P.11
De La Chapelle, A.12
Percesepe, A.13
Ahtola, H.14
Harkonen, N.15
Julkunen, R.16
Kangas, E.17
Ojala, S.18
Tulikoura, J.19
Valkamo, E.20
more..
-
12
-
-
0034799747
-
The colon cancer burden of genetically defined hereditary nonpolyposis colon cancer
-
Samowitz, W. S., Curtin, K., Lin, H. H., Robertson, M. A., Schaffer, D., Nichols, M., Gruenthal, K., Leppert, M. F. and Slattery, M. L. (2001) The colon cancer burden of genetically defined hereditary nonpolyposis colon cancer. Gastroenterology, 121, 830-838. (Pubitemid 32959394)
-
(2001)
Gastroenterology
, vol.121
, Issue.4
, pp. 830-838
-
-
Samowitz, W.S.1
Curtin, K.2
Lin, H.H.3
Robertson, M.A.4
Schaffer, D.5
Nichols, M.6
Gruenthal, K.7
Leppert, M.F.8
Slattery, M.L.9
-
13
-
-
56449107092
-
Recent advances in colorectal cancer genetics and diagnostics
-
Cheah, P. Y. (2009) Recent advances in colorectal cancer genetics and diagnostics. Crit. Rev. Oncol. Hematol., 69, 45-55.
-
(2009)
Crit. Rev. Oncol. Hematol.
, vol.69
, pp. 45-55
-
-
Cheah, P.Y.1
-
14
-
-
75549083862
-
COGENT (COlorectal cancer GENe Tics): An international consortium to study the role of polymorphic variation on the risk of colorectal cancer
-
Tomlinson, I. P., Dunlop, M., Campbell, H. et al. (2010) COGENT (COlorectal cancer GENe Tics): an international consortium to study the role of polymorphic variation on the risk of colorectal cancer. Br. J. Cancer, 102, 447-454.
-
(2010)
Br. J. Cancer
, vol.102
, pp. 447-454
-
-
Tomlinson, I.P.1
Dunlop, M.2
Campbell, H.3
-
15
-
-
61649127794
-
Cancer risks in Crohn disease patients
-
Hemminki, K., Li, X., Sundquist, J. and Sundquist, K. (2009) Cancer risks in Crohn disease patients. Ann. Oncol., 20, 574-580.
-
(2009)
Ann. Oncol.
, vol.20
, pp. 574-580
-
-
Hemminki, K.1
Li, X.2
Sundquist, J.3
Sundquist, K.4
-
16
-
-
59249098280
-
Colorectal cancer surveillance in inflammatory bowel disease: The search continues
-
Ahmadi, A., Polyak, S. and Draganov, P. V. (2009) Colorectal cancer surveillance in inflammatory bowel disease: the search continues. World J. Gastroenterol, 15, 61-66.
-
(2009)
World J. Gastroenterol
, vol.15
, pp. 61-66
-
-
Ahmadi, A.1
Polyak, S.2
Draganov, P.V.3
-
17
-
-
33744973579
-
Cancer genetics: Colorectal cancer as a model
-
DOI 10.1007/s10038-006-0373-x
-
Bodmer, W. F. (2006) Cancer genetics: colorectal cancer as a model. J. Hum. Genet., 51, 391-396. (Pubitemid 43863773)
-
(2006)
Journal of Human Genetics
, vol.51
, Issue.5
, pp. 391-396
-
-
Bodmer, W.F.1
-
18
-
-
77956186497
-
Effect ofgenome-wide association studies, direct-to-consumer genetic testing, and high-speed sequencing technologies on predictive genetic counselling for cancer risk
-
Speicher, M. R., Geigl, J. B. and Tomlinson, I. P. (2010) Effect ofgenome-wide association studies, direct-to-consumer genetic testing, and high-speed sequencing technologies on predictive genetic counselling for cancer risk. Lancet Oncol., 11, 890-898.
-
(2010)
Lancet Oncol.
, vol.11
, pp. 890-898
-
-
Speicher, M.R.1
Geigl, J.B.2
Tomlinson, I.P.3
-
19
-
-
0034644185
-
Environmental and heritable factors in the causation of cancer: Analyses of cohorts of twins from Sweden, Denmark, and Finland
-
DOI 10.1056/NEJM200007133430201
-
Lichtenstein, P., Holm, N. V., Verkasalo, P. K., Iliadou, A., Kaprio, J., Koskenvuo, M., Pukkala, E., Skytthe, A. and Hemminki, K. (2000) Environmental and heritable factors in the causation of cancer\-analyses of cohorts of twins from Sweden, Denmark, and Finland. N. Engl. J. Med., 343, 78-85. (Pubitemid 30451850)
-
(2000)
New England Journal of Medicine
, vol.343
, Issue.2
, pp. 78-85
-
-
Lichtenstein, P.1
Holm, N.V.2
Verkasalo, P.K.3
Iliadou, A.4
Kaprio, J.5
Koskenvuo, M.6
Pukkala, E.7
Skytthe, A.8
Hemminki, K.9
-
20
-
-
33846332027
-
Explaining the familial colorectal cancer risk associated with mismatch repair (MMR)-deficient and MMR-stable tumors
-
DOI 10.1158/1078-0432.CCR-06-1256
-
Aaltonen, L., Johns, L., Jarvinen, H., Mecklin, J. P. and Houlston, R. (2007) Explaining the familial colorectal cancer risk associated with mismatch repair (MMR)-deficient and MMR-stable tumors. Clin. Cancer Res., 13, 356-361. (Pubitemid 46121890)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.1
, pp. 356-361
-
-
Aaltonen, L.1
Johns, L.2
Jarvinen, H.3
Mecklin, J.-P.4
Houlston, R.5
-
21
-
-
0036845568
-
Low-penetrance genes and their involvement in colorectal cancer susceptibility
-
de Jong, M. M., Nolte, I. M., te Meerman, G. J., van der Graaf, W. T., de Vries, E. G., Sijmons, R. H., Hofstra, R. M. and Kleibeuker, J. H. (2002) Low-penetrance genes and their involvement in colorectal cancer susceptibility. Cancer Epidemiol. Biomarkers Prev., 11, 1332-1352. (Pubitemid 35340368)
-
(2002)
Cancer Epidemiology Biomarkers and Prevention
, vol.11
, Issue.11
, pp. 1332-1352
-
-
De Jong, M.M.1
Nolte, I.M.2
Te Meerman, G.J.3
Van Der Graaf, W.T.A.4
De Vries, E.G.E.5
Sijmons, R.H.6
Hofstra, R.M.W.7
Kleibeuker, J.H.8
-
22
-
-
12344335470
-
Relationship between metabolic enzyme polymorphism and colorectal cancer
-
Chen, K., Jiang, Q. T. and He, H. Q. (2005) Relationship between metabolic enzyme polymorphism and colorectal cancer. World J. Gastro-enterol., 11, 331-335. (Pubitemid 40125233)
-
(2005)
World Journal of Gastroenterology
, vol.11
, Issue.3
, pp. 331-335
-
-
Chen, K.1
Jiang, Q.-T.2
He, H.-Q.3
-
23
-
-
33744729998
-
NAD(P)H:quinone oxidoreductase 1 (NQO1) Pro187Ser polymorphism and the risk of lung, bladder, and colorectal cancers: A meta-analysis
-
DOI 10.1158/1055-9965.EPI-05-0899
-
Chao, C., Zhang, Z. F., Berthiller, J., Boffetta, P. and Hashibe, M. (2006) NAD(P)H:quinone oxidoreductase 1 (NQO1) Pro187Ser polymorphism and the risk of lung, bladder, and colorectal cancers: a meta-analysis. Cancer Epidemiol. Biomarkers Prev., 15, 979-987. (Pubitemid 43823527)
-
(2006)
Cancer Epidemiology Biomarkers and Prevention
, vol.15
, Issue.5
, pp. 979-987
-
-
Chao, C.1
Zhang, Z.-F.2
Berthiller, J.3
Boffetta, P.4
Hashibe, M.5
-
24
-
-
33846811416
-
MTHFR C677T and colorectal cancer risk: A meta-analysis of 25 populations
-
DOI 10.1002/ijc.22440
-
Hubner, R. A. and Houlston, R. S. (2007) MTHFR C677T and colorectal cancer risk: a meta-analysis of 25 populations. Int. J. Cancer, 120, 1027-1035. (Pubitemid 46214302)
-
(2007)
International Journal of Cancer
, vol.120
, Issue.5
, pp. 1027-1035
-
-
Hubner, R.A.1
Houlston, R.S.2
-
25
-
-
33845869785
-
Different roles of MTHFR C677T and A1298C polymorphisms in colorectal adenoma and colorectal cancer: A meta-analysis
-
DOI 10.1007/s10038-006-0082-5
-
Huang, Y., Han, S., Li, Y., Mao, Y. and Xie, Y. (2007) Different roles of MTHFR C677T and A1298C polymorphisms in colorectal adenoma and colorectal cancer: a meta-analysis. J. Hum. Genet., 52, 73-85. (Pubitemid 46020567)
-
(2007)
Journal of Human Genetics
, vol.52
, Issue.1
, pp. 73-85
-
-
Huang, Y.1
Han, S.2
Li, Y.3
Mao, Y.4
Xie, Y.5
-
26
-
-
42549093639
-
The association of cyclin D1 G870A and E-cadherin C-160A polymorphisms with the risk of colorectal cancer in a case control study and meta-analysis
-
DOI 10.1002/ijc.23363
-
Tan, X. L., Nieters, A., Kropp, S., Hoffmeister, M., Brenner, H. and Chang-Claude, J. (2008) The association of cyclin D1 G870A and E-cadherin C-160A polymorphisms with the risk of colorectal cancer in a case control study and meta-analysis. Int. J. Cancer, 122, 2573-2580. (Pubitemid 351590492)
-
(2008)
International Journal of Cancer
, vol.122
, Issue.11
, pp. 2573-2580
-
-
Tan, X.-L.1
Nieters, A.2
Kropp, S.3
Hoffmeister, M.4
Brenner, H.5
Chang-Claude, J.6
-
27
-
-
37549009957
-
A meta-analysis of DNA repair gene XPC polymorphisms and cancer risk
-
Zhang, D., Chen, C., Fu, X., Gu, S., Mao, Y., Xie, Y., Huang, Y. and Li, Y. (2008) A meta-analysis of DNA repair gene XPC polymorphisms and cancer risk. J. Hum. Genet., 53, 18-33.
-
(2008)
J. Hum. Genet.
, vol.53
, pp. 18-33
-
-
Zhang, D.1
Chen, C.2
Fu, X.3
Gu, S.4
Mao, Y.5
Xie, Y.6
Huang, Y.7
Li, Y.8
-
28
-
-
35648937584
-
A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk
-
DOI 10.1038/ng.2007.18, PII NG200718
-
Broderick, P., Carvajal-Carmona, L., Pittman, A. M. et al. (2007) A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk. Nat. Genet., 39, 1315-1317. (Pubitemid 350034998)
-
(2007)
Nature Genetics
, vol.39
, Issue.11
, pp. 1315-1317
-
-
Broderick, P.1
Carvajal-Carmona, L.2
Pittman, A.M.3
Webb, E.4
Howarth, K.5
Rowan, A.6
Lubbe, S.7
Spain, S.8
Sullivan, K.9
Fielding, S.10
Jaeger, E.11
Vijayakrishnan, J.12
Kemp, Z.13
Gorman, M.14
Chandler, I.15
Papaemmanuil, E.16
Penegar, S.17
Wood, W.18
Sellick, G.19
Qureshi, M.20
Teixeira, A.21
Domingo, E.22
Barclay, E.23
Martin, L.24
Sieber, O.25
Kerr, D.26
Gray, R.27
Peto, J.28
Cazier, J.-B.29
Tomlinson, I.30
Houlston, R.S.31
more..
-
29
-
-
34547121725
-
A common genetic risk factor for colorectal and prostate cancer
-
DOI 10.1038/ng2098, PII NG2098
-
Haiman, C. A., Le Marchand, L., Yamamato, J., Stram, D. O., Sheng, X., Kolonel, L. N., Wu, A. H., Reich, D. and Henderson, B. E. (2007) A common genetic risk factor for colorectal and prostate cancer. Nat. Genet., 39, 954-956. (Pubitemid 47185184)
-
(2007)
Nature Genetics
, vol.39
, Issue.8
, pp. 954-956
-
-
Haiman, C.A.1
Le Marchand, L.2
Yamamato, J.3
Stram, D.O.4
Sheng, X.5
Kolonel, L.N.6
Wu, A.H.7
Reich, D.8
Henderson, B.E.9
-
30
-
-
34547498546
-
A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21
-
DOI 10.1038/ng2085, PII NG2085
-
Tomlinson, I., Webb, E., Carvajal-Carmona, L. et al. (2007) A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21. Nat. Genet., 39, 984-988. (Pubitemid 47185182)
-
(2007)
Nature Genetics
, vol.39
, Issue.8
, pp. 984-988
-
-
Tomlinson, I.1
Webb, E.2
Carvajal-Carmona, L.3
Broderick, P.4
Kemp, Z.5
Spain, S.6
Penegar, S.7
Chandler, I.8
Gorman, M.9
Wood, W.10
Barclay, E.11
Lubbe, S.12
Martin, L.13
Sellick, G.14
Jaeger, E.15
Hubner, R.16
Wild, R.17
Rowan, A.18
Fielding, S.19
Howarth, K.20
Silver, A.21
Atkin, W.22
Muir, K.23
Logan, R.24
Kerr, D.25
Johnstone, E.26
Sieber, O.27
Gray, R.28
Thomas, H.29
Peto, J.30
Cazier, J.-B.31
Houlston, R.32
more..
-
31
-
-
34547092701
-
Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24
-
DOI 10.1038/ng2089, PII NG2089
-
Zanke, B. W., Greenwood, C. M., Rangrej, J. et al. (2007) Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24. Nat. Genet., 39, 989-994. (Pubitemid 47185183)
-
(2007)
Nature Genetics
, vol.39
, Issue.8
, pp. 989-994
-
-
Zanke, B.W.1
Greenwood, C.M.2
Rangrej, J.3
Kustra, R.4
Tenesa, A.5
Farrington, S.M.6
Prendergast, J.7
Olschwang, S.8
Chiang, T.9
Crowdy, E.10
Ferretti, V.11
Laflamme, P.12
Sundararajan, S.13
Roumy, S.14
Olivier, J.-F.15
Robidoux, F.16
Sladek, R.17
Montpetit, A.18
Campbell, P.19
Bezieau, S.20
O'Shea, A.M.21
Zogopoulos, G.22
Cotterchio, M.23
Newcomb, P.24
McLaughlin, J.25
Younghusband, B.26
Green, R.27
Green, J.28
Porteous, M.E.M.29
Campbell, H.30
Blanche, H.31
Sahbatou, M.32
Tubacher, E.33
Bonaiti-Pellie, C.34
Buecher, B.35
Riboli, E.36
Kury, S.37
Chanock, S.J.38
Potter, J.39
Thomas, G.40
Gallinger, S.41
Hudson, T.J.42
Dunlop, M.G.43
more..
-
32
-
-
56749176944
-
Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer
-
Houlston, R. S., Webb, E., Broderick, P. et al. (2008) Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer. Nat. Genet., 40, 1426-1435.
-
(2008)
Nat. Genet.
, vol.40
, pp. 1426-1435
-
-
Houlston, R.S.1
Webb, E.2
Broderick, P.3
-
33
-
-
37549072226
-
Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13.3 influence colorectal cancer risk
-
Jaeger, E., Webb, E., Howarth, K. etal. (2008) Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13.3 influence colorectal cancer risk. Nat. Genet., 40, 26-28.
-
(2008)
Nat. Genet.
, vol.40
, pp. 26-28
-
-
Jaeger, E.1
Webb, E.2
Howarth, K.3
-
34
-
-
56049119387
-
Refinement of the basis and impact of common 11q23.1 variation to the risk of developing colorectal cancer
-
Pittman, A. M., Webb, E., Carvajal-Carmona, L. et al. (2008) Refinement of the basis and impact of common 11q23.1 variation to the risk of developing colorectal cancer. Hum. Mol. Genet., 17, 3720-3727.
-
(2008)
Hum. Mol. Genet.
, vol.17
, pp. 3720-3727
-
-
Pittman, A.M.1
Webb, E.2
Carvajal-Carmona, L.3
-
35
-
-
42649124305
-
Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21
-
DOI 10.1038/ng.133, PII NG133
-
Tenesa, A., Farrington, S. M., Prendergast, J. G. etal. (2008) Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21. Nat. Genet., 40, 631-637. (Pubitemid 351601219)
-
(2008)
Nature Genetics
, vol.40
, Issue.5
, pp. 631-637
-
-
Tenesa, A.1
Farrington, S.M.2
Prendergast, J.G.D.3
Porteous, M.E.4
Walker, M.5
Haq, N.6
Barnetson, R.A.7
Theodoratou, E.8
Cetnarskyj, R.9
Cartwright, N.10
Semple, C.11
Clark, A.J.12
Reid, F.J.L.13
Smith, L.A.14
Kavoussanakis, K.15
Koessler, T.16
Pharoah, P.D.P.17
Buch, S.18
Schafmayer, C.19
Tepel, J.20
Schreiber, S.21
Volzke, H.22
Schmidt, C.O.23
Hampe, J.24
Chang-Claude, J.25
Hoffmeister, M.26
Brenner, H.27
Wilkening, S.28
Canzian, F.29
Capella, G.30
Moreno, V.31
Deary, I.J.32
Starr, J.M.33
Tomlinson, I.P.M.34
Kemp, Z.35
Howarth, K.36
Carvajal-Carmona, L.37
Webb, E.38
Broderick, P.39
Vijayakrishnan, J.40
Houlston, R.S.41
Rennert, G.42
Ballinger, D.43
Rozek, L.44
Gruber, S.B.45
Matsuda, K.46
Kidokoro, T.47
Nakamura, Y.48
Zanke, B.W.49
Greenwood, C.M.T.50
Rangrej, J.51
Kustra, R.52
Montpetit, A.53
Hudson, T.J.54
Gallinger, S.55
Campbell, H.56
Dunlop, M.G.57
more..
-
36
-
-
42649136554
-
A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3
-
DOI 10.1038/ng.111, PII NG111
-
Tomlinson, I. P., Webb, E., Carvajal-Carmona, L. et al. (2008) A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3. Nat. Genet., 40, 623-630. (Pubitemid 351601204)
-
(2008)
Nature Genetics
, vol.40
, Issue.5
, pp. 623-630
-
-
Tomlinson, I.P.M.1
Webb, E.2
Carvajal-Carmona, L.3
Broderick, P.4
Howarth, K.5
Pittman, A.M.6
Spain, S.7
Lubbe, S.8
Walther, A.9
Sullivan, K.10
Jaeger, E.11
Fielding, S.12
Rowan, A.13
Vijayakrishnan, J.14
Domingo, E.15
Chandler, I.16
Kemp, Z.17
Qureshi, M.18
Farrington, S.M.19
Tenesa, A.20
Prendergast, J.G.D.21
Barnetson, R.A.22
Penegar, S.23
Barclay, E.24
Wood, W.25
Martin, L.26
Gorman, M.27
Thomas, H.28
Peto, J.29
Bishop, D.T.30
Gray, R.31
Maher, E.R.32
Lucassen, A.33
Kerr, D.34
Evans, D.G.R.35
Schafmayer, C.36
Buch, S.37
Volzke, H.38
Hampe, J.39
Schreiber, S.40
John, U.41
Koessler, T.42
Pharoah, P.43
Van Wezel, T.44
Morreau, H.45
Wijnen, J.T.46
Hopper, J.L.47
Southey, M.C.48
Giles, G.G.49
Severi, G.50
Castellvi-Bel, S.51
Ruiz-Ponte, C.52
Carracedo, A.53
Castells, A.54
Forsti, A.55
Hemminki, K.56
Vodicka, P.57
Naccarati, A.58
Lipton, L.59
Ho, J.W.C.60
Cheng, K.K.61
Sham, P.C.62
Luk, J.63
Agundez, J.A.G.64
Ladero, J.M.65
De La Hoya, M.66
Caldes, T.67
Niittymaki, I.68
Tuupanen, S.69
Karhu, A.70
Aaltonen, L.71
Cazier, J.-B.72
Campbell, H.73
Dunlop, M.G.74
Houlston, R.S.75
more..
-
37
-
-
70349736105
-
Colorectal cancer risk is not associated with increased levels of homozygosity in a population from the United Kingdom
-
Spain, S. L., Cazier, J. B., Houlston, R., Carvajal-Carmona, L. and Tomlinson, I. (2009) Colorectal cancer risk is not associated with increased levels of homozygosity in a population from the United Kingdom. Cancer Res., 69, 7422-7429.
-
(2009)
Cancer Res.
, vol.69
, pp. 7422-7429
-
-
Spain, S.L.1
Cazier, J.B.2
Houlston, R.3
Carvajal-Carmona, L.4
Tomlinson, I.5
-
38
-
-
78049353079
-
Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33
-
Houlston, R. S., Cheadle, J., Dobbins, S. E. et al. (2010) Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33. Nat. Genet., 42, 973-977.
-
(2010)
Nat. Genet.
, vol.42
, pp. 973-977
-
-
Houlston, R.S.1
Cheadle, J.2
Dobbins, S.E.3
-
39
-
-
77956281205
-
Genome-wide association study for colorectal cancer identifies risk polymorphisms in German familial cases and implicates MAPK signalling pathways in disease susceptibility
-
Lascorz, J., Forsti, A., Chen, B. et al. (2010) Genome-wide association study for colorectal cancer identifies risk polymorphisms in German familial cases and implicates MAPK signalling pathways in disease susceptibility. Carcinogenesis, 31, 1612-1619.
-
(2010)
Carcinogenesis
, vol.31
, pp. 1612-1619
-
-
Lascorz, J.1
Forsti, A.2
Chen, B.3
-
40
-
-
79751534602
-
Treatment ofcolorectal cancer with unresectable synchronous liver-only metastases with combined therapeutic modalities
-
Cui, Y., Li, H., Wu, Q., Zhang, T., Kong, D., Song, T., Ru, T., Chen, P. and Li, Q. (2011) Treatment ofcolorectal cancer with unresectable synchronous liver-only metastases with combined therapeutic modalities. J. Gastrointest. Surg., 15, 285-293.
-
(2011)
J. Gastrointest. Surg.
, vol.15
, pp. 285-293
-
-
Cui, Y.1
Li, H.2
Wu, Q.3
Zhang, T.4
Kong, D.5
Song, T.6
Ru, T.7
Chen, P.8
Li, Q.9
-
41
-
-
79955860324
-
Common variant in 6q26-q27 is associated with distal colon cancer in an Asian population
-
Cui, R., Okada, Y., Jang, S. G. et al. (2011) Common variant in 6q26-q27 is associated with distal colon cancer in an Asian population. Gut, 60, 799-805.
-
(2011)
Gut
, vol.60
, pp. 799-805
-
-
Cui, R.1
Okada, Y.2
Jang, S.G.3
-
42
-
-
79955780907
-
Genotype-environment interactions in microsatellite stable/microsatellite instability-low colorectal cancer: Results from a genome-wide association study
-
Figueiredo, J. C., Lewinger, J. P., Song, C. et al. (2011) Genotype-environment interactions in microsatellite stable/microsatellite instability-low colorectal cancer: results from a genome-wide association study. Cancer Epidemiol. Biomarkers Prev., 20, 758-766.
-
(2011)
Cancer Epidemiol. Biomarkers Prev.
, vol.20
, pp. 758-766
-
-
Figueiredo, J.C.1
Lewinger, J.P.2
Song, C.3
-
43
-
-
79959851441
-
Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancer
-
Tomlinson, I. P., Carvajal-Carmona, L. G., Dobbins, S. E. et al. (2011) Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancer. PLo S Genet., 7, e1002105.
-
(2011)
PLo S Genet.
, vol.7
-
-
Tomlinson, I.P.1
Carvajal-Carmona, L.G.2
Dobbins, S.E.3
-
44
-
-
67349245787
-
New insights into the aetiology of colorectal cancer from genome-wide association studies
-
Tenesa, A. and Dunlop, M. G. (2009) New insights into the aetiology of colorectal cancer from genome-wide association studies. Nat. Rev. Genet., 10, 353-358.
-
(2009)
Nat. Rev. Genet.
, vol.10
, pp. 353-358
-
-
Tenesa, A.1
Dunlop, M.G.2
-
45
-
-
68149170044
-
The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling
-
Tuupanen, S., Turunen, M., Lehtonen, R. et al. (2009) The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling. Nat. Genet., 41, 885-890.
-
(2009)
Nat. Genet.
, vol.41
, pp. 885-890
-
-
Tuupanen, S.1
Turunen, M.2
Lehtonen, R.3
-
46
-
-
78049415226
-
Allelic variation at the 8q23.3 colorectal cancer risk locus functions as a cis-acting regulator of EIF3H
-
Pittman, A. M., Naranjo, S., Jalava, S. E. et al. (2010) Allelic variation at the 8q23.3 colorectal cancer risk locus functions as a cis-acting regulator of EIF3H. PLo S Genet., 6, e1001126.
-
(2010)
PLo S Genet.
, vol.6
-
-
Pittman, A.M.1
Naranjo, S.2
Jalava, S.E.3
-
47
-
-
79959789728
-
Fine-mapping of colorectal cancer susceptibility loci at 8q23.3 16q22.1 and 19q13.11: Refinement of association signals and use of in silico analysis to suggest functional variation and unexpected candidate target genes
-
Carvajal-Carmona, L. G., Cazier, J. B., Jones, A. M. et al. (2011) Fine-mapping of colorectal cancer susceptibility loci at 8q23.3, 16q22.1 and 19q13.11: refinement of association signals and use of in silico analysis to suggest functional variation and unexpected candidate target genes. Hum. Mol. Genet., 20, 2879-2888.
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 2879-2888
-
-
Carvajal-Carmona, L.G.1
Cazier, J.B.2
Jones, A.M.3
-
48
-
-
79851509739
-
Systematic search for enhancer elements and somatic allelic imbalance at seven low-penetrance colorectal cancer predisposition loci
-
Niittymaki, I., Tuupanen, S., Li, Y., Jarvinen, H., Mecklin, J. P., Tomlinson, I. P., Houlston, R. S., Karhu, A. and Aaltonen, L. A. (2011) Systematic search for enhancer elements and somatic allelic imbalance at seven low-penetrance colorectal cancer predisposition loci. BMC Med. Genet., 12, 23.
-
(2011)
BMC Med. Genet.
, vol.12
, pp. 23
-
-
Niittymaki, I.1
Tuupanen, S.2
Li, Y.3
Jarvinen, H.4
Mecklin, J.P.5
Tomlinson, I.P.6
Houlston, R.S.7
Karhu, A.8
Aaltonen, L.A.9
-
49
-
-
77955362763
-
Analysis of SNPs with an effect on gene expression identifies UBE2L3 and BCL3 as potential new risk genes for Crohn's disease
-
Fransen, K., Visschedijk, M. C., van Sommeren, S. et al. (2010) Analysis of SNPs with an effect on gene expression identifies UBE2L3 and BCL3 as potential new risk genes for Crohn's disease. Hum. Mol. Genet., 19, 3482-3488.
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 3482-3488
-
-
Fransen, K.1
Visschedijk, M.C.2
Van Sommeren, S.3
-
50
-
-
78149267111
-
Mapping of numerous disease-associated expression polymorphisms in primary peripheral blood CD4+ lymphocytes
-
Murphy, A., Chu, J. H., Xu, M. etal. (2010) Mapping of numerous disease-associated expression polymorphisms in primary peripheral blood CD4+ lymphocytes. Hum. Mol. Genet., 19, 4745-4757.
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 4745-4757
-
-
Murphy, A.1
Chu, J.H.2
Xu, M.3
-
51
-
-
74849111621
-
Identification of intergenic trans-regulatory RNAs containing a disease-linked SNP sequence and targeting cell cycle progression/differentiation pathways in multiple common human disorders
-
Glinskii, A. B., Ma, J., Ma, S., Grant, D., Lim, C. U., Sell, S. and Glinsky, G. V. (2009) Identification of intergenic trans-regulatory RNAs containing a disease-linked SNP sequence and targeting cell cycle progression/differentiation pathways in multiple common human disorders. Cell Cycle, 8, 3925-3942.
-
(2009)
Cell Cycle
, vol.8
, pp. 3925-3942
-
-
Glinskii, A.B.1
Ma, J.2
Ma, S.3
Grant, D.4
Lim, C.U.5
Sell, S.6
Glinsky, G.V.7
-
52
-
-
77952367694
-
Candidate causal regulatory effects by integration of expression QTLs with complex trait genetic associations
-
Nica, A. C., Montgomery, S. B., Dimas, A. S., Stranger, B. E., Beazley, C., Barroso, I. and Dermitzakis, E. T. (2010) Candidate causal regulatory effects by integration of expression QTLs with complex trait genetic associations. PLo S Genet., 6, e1000895.
-
(2010)
PLo S Genet.
, vol.6
-
-
Nica, A.C.1
Montgomery, S.B.2
Dimas, A.S.3
Stranger, B.E.4
Beazley, C.5
Barroso, I.6
Dermitzakis, E.T.7
-
53
-
-
48849115097
-
Emerging genomic technologies and the concept of personalized medicine
-
Glinskii, V. G. and Glinsky, G. V. (2008) Emerging genomic technologies and the concept of personalized medicine. Cell Cycle, 7, 2278-2285.
-
(2008)
Cell Cycle
, vol.7
, pp. 2278-2285
-
-
Glinskii, V.G.1
Glinsky, G.V.2
-
54
-
-
27644482314
-
Mapping determinants of human gene expression by regional and genome-wide association
-
DOI 10.1038/nature04244, PII N04244
-
Cheung, V. G., Spielman, R. S., Ewens, K. G., Weber, T. M., Morley, M. and Burdick, J. T. (2005) Mapping determinants of human gene expression by regional and genome-wide association. Nature, 437, 1365-1369. (Pubitemid 41568683)
-
(2005)
Nature
, vol.437
, Issue.7063
, pp. 1365-1369
-
-
Cheung, V.G.1
Spielman, R.S.2
Ewens, K.G.3
Weber, T.M.4
Morley, M.5
Burdick, J.T.6
-
55
-
-
34548805282
-
A genome-wide association study of global gene expression
-
DOI 10.1038/ng2109, PII NG2109
-
Dixon, A. L., Liang, L., Moffatt, M. F. et al. (2007) A genome-wide association study of global gene expression. Nat. Genet., 39, 1202-1207. (Pubitemid 47482680)
-
(2007)
Nature Genetics
, vol.39
, Issue.10
, pp. 1202-1207
-
-
Dixon, A.L.1
Liang, L.2
Moffatt, M.F.3
Chen, W.4
Heath, S.5
Wong, K.C.C.6
Taylor, J.7
Burnett, E.8
Gut, I.9
Farrall, M.10
Lathrop, G.M.11
Abecasis, G.R.12
Cookson, W.O.C.13
-
56
-
-
42649086788
-
From gene expression to disease risk
-
DOI 10.1038/ng0508-492, PII NG0508492
-
Dermitzakis, E. T. (2008) From gene expression to disease risk. Nat. Genet., 40, 492-493. (Pubitemid 351601229)
-
(2008)
Nature Genetics
, vol.40
, Issue.5
, pp. 492-493
-
-
Dermitzakis, E.T.1
-
57
-
-
77957920003
-
Polymorphic cis- and trans-regulation of human gene expression
-
Cheung, V. G., Nayak, R. R., Wang, I. X., Elwyn, S., Cousins, S. M., Morley, M. and Spielman, R. S. (2010) Polymorphic cis- and trans-regulation of human gene expression. PLo S Biol, 6, e1000480.
-
(2010)
PLo S Biol
, vol.6
-
-
Cheung, V.G.1
Nayak, R.R.2
Wang, I.X.3
Elwyn, S.4
Cousins, S.M.5
Morley, M.6
Spielman, R.S.7
-
58
-
-
4043128071
-
Genetic analysis of genome-wide variation in human gene expression
-
DOI 10.1038/nature02797
-
Morley, M., Molony, C. M., Weber, T. M., Devlin, J. L., Ewens, K. G., Spielman, R. S. and Cheung, V. G. (2004) Genetic analysis of genome-wide variation in human gene expression. Nature, 430, 743-747. (Pubitemid 39071339)
-
(2004)
Nature
, vol.430
, Issue.7001
, pp. 743-747
-
-
Morloy, M.1
Molony, C.M.2
Weber, T.M.3
Devlin, J.L.4
Ewens, K.G.5
Spielman, R.S.6
Cheung, V.G.7
-
59
-
-
0016669094
-
Evolution at two levels in humans and chimpanzees
-
King, M. C. and Wilson, A. C. (1975) Evolution at two levels in humans and chimpanzees. Science, 188, 107-116.
-
(1975)
Science
, vol.188
, pp. 107-116
-
-
King, M.C.1
Wilson, A.C.2
-
60
-
-
28744454762
-
Gene expression variation and expression quantitative trait mapping of human chromosome 21 genes
-
DOI 10.1093/hmg/ddi404
-
Deutsch, S., Lyle, R., Dermitzakis, E. T. et al. (2005) Gene expression variation and expression quantitative trait mapping of human chromosome 21 genes. Hum. Mol. Genet., 14, 3741-3749. (Pubitemid 41754672)
-
(2005)
Human Molecular Genetics
, vol.14
, Issue.23
, pp. 3741-3749
-
-
Deutsch, S.1
Lyle, R.2
Dermitzakis, E.T.3
Attar, H.4
Subrahmanyan, L.5
Gehrig, C.6
Parand, L.7
Gagnebin, M.8
Rougemont, J.9
Jongeneel, C.V.10
Antonarakis, S.E.11
-
61
-
-
68949211709
-
Genetics of human gene expression: Mapping DNA variants that influence gene expression
-
Cheung, V. G. and Spielman, R. S. (2009) Genetics of human gene expression: mapping DNA variants that influence gene expression. Nat. Rev. Genet., 10, 595-604.
-
(2009)
Nat. Rev. Genet.
, vol.10
, pp. 595-604
-
-
Cheung, V.G.1
Spielman, R.S.2
-
62
-
-
0035400051
-
Genetical genomics: The added value from segregation
-
DOI 10.1016/S0168-9525(01)02310-1, PII S0168952501023101
-
Jansen, R. C. and Nap, J. P. (2001) Genetical genomics: the added value from segregation. Trends Genet., 17, 388-391. (Pubitemid 32545383)
-
(2001)
Trends in Genetics
, vol.17
, Issue.7
, pp. 388-391
-
-
Jansen, R.C.1
Nap, J.-P.2
-
63
-
-
60349092402
-
Mapping complex disease traits with global gene expression
-
Cookson, W., Liang, L., Abecasis, G., Moffatt, M. and Lathrop, M. (2009) Mapping complex disease traits with global gene expression. Nat. Rev. Genet., 10, 184-194.
-
(2009)
Nat. Rev. Genet.
, vol.10
, pp. 184-194
-
-
Cookson, W.1
Liang, L.2
Abecasis, G.3
Moffatt, M.4
Lathrop, M.5
-
64
-
-
84975804424
-
Mapping copy number variation by population-scale genome sequencing
-
Mills, R. E., Walter, K., Stewart, C. et al. (2011) Mapping copy number variation by population-scale genome sequencing. Nature, 470, 59-65.
-
(2011)
Nature
, vol.470
, pp. 59-65
-
-
Mills, R.E.1
Walter, K.2
Stewart, C.3
-
65
-
-
77956637896
-
Genetics and beyond\-The transcriptome of human monocytes and disease susceptibility
-
Zeller, T., Wild, P., Szymczak, S. et al. (2010) Genetics and beyond\-the transcriptome of human monocytes and disease susceptibility. PLo S One,5, e10693.
-
(2010)
PLo S One
, vol.5
-
-
Zeller, T.1
Wild, P.2
Szymczak, S.3
-
66
-
-
77950341944
-
Genetic variants and risk of lung cancer in never smokers: A genome-wide association study
-
Li, Y., Sheu, C. C., Ye, Y. et al. (2010) Genetic variants and risk of lung cancer in never smokers: a genome-wide association study. Lancet Oncol., 11, 321-330.
-
(2010)
Lancet Oncol.
, vol.11
, pp. 321-330
-
-
Li, Y.1
Sheu, C.C.2
Ye, Y.3
-
67
-
-
57149114316
-
Genetic analysis of human traits in vitro: Drug response and gene expression in lymphoblastoid cell lines
-
Choy, E., Yelensky, R., Bonakdar, S. et al. (2008) Genetic analysis of human traits in vitro: drug response and gene expression in lymphoblastoid cell lines. PLo S Genet., 4, e1000287.
-
(2008)
PLo S Genet.
, vol.4
-
-
Choy, E.1
Yelensky, R.2
Bonakdar, S.3
-
68
-
-
38849093314
-
The influence of genetic variation on gene expression
-
DOI 10.1101/gr.6981507
-
Williams, R. B., Chan, E. K., Cowley, M. J. and Little, P. F. (2007) The influence of genetic variation on gene expression. Genome Res., 17, 1707-1716. (Pubitemid 351359994)
-
(2007)
Genome Research
, vol.17
, Issue.12
, pp. 1707-1716
-
-
Williams, R.B.H.1
Chan, E.K.F.2
Cowley, M.J.3
Little, P.F.R.4
-
69
-
-
33750204290
-
Genetics of global gene expression
-
DOI 10.1038/nrg1964, PII NRG1964
-
Rockman, M. V. and Kruglyak, L. (2006) Genetics of global gene expression. Nat. Rev. Genet., 7, 862-872. (Pubitemid 44607102)
-
(2006)
Nature Reviews Genetics
, vol.7
, Issue.11
, pp. 862-872
-
-
Rockman, M.V.1
Kruglyak, L.2
-
70
-
-
38049048611
-
Searching for master regulators of transcription in ahuman gene expression data set
-
Buil, A., Perera-Lluna, A., Souto, R., Peralta, J. M., Almasy, L., Vallverdu, M., Caminal, P. and Soria, J. M. (2007) Searching for master regulators of transcription in ahuman gene expression data set. BMC Proc., 1 (Suppl. 1), S81.
-
(2007)
BMC Proc.
, vol.1
, Issue.SUPPL. 1
-
-
Buil, A.1
Perera-Lluna, A.2
Souto, R.3
Peralta, J.M.4
Almasy, L.5
Vallverdu, M.6
Caminal, P.7
Soria, J.M.8
-
71
-
-
20144386111
-
Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function
-
DOI 10.1038/ng1518
-
Chesler, E. J., Lu, L., Shou, S. et al. (2005) Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function. Nat. Genet., 37, 233-242. (Pubitemid 41716250)
-
(2005)
Nature Genetics
, vol.37
, Issue.3
, pp. 233-242
-
-
Chesler, E.J.1
Lu, L.2
Shou, S.3
Qu, Y.4
Gu, J.5
Wang, J.6
Hsu, H.C.7
Mountz, J.D.8
Baldwin, N.E.9
Langston, M.A.10
Threadgill, D.W.11
Manly, K.F.12
Williams, R.W.13
-
72
-
-
0037177625
-
Genetic dissection of transcriptional regulation in budding yeast
-
DOI 10.1126/science.1069516
-
Brem, R. B., Yvert, G., Clinton, R. and Kruglyak, L. (2002) Genetic dissection of transcriptional regulation in budding yeast. Science, 296, 752-755. (Pubitemid 34442007)
-
(2002)
Science
, vol.296
, Issue.5568
, pp. 752-755
-
-
Brem, R.B.1
Yvert, G.2
Clinton, R.3
Kruglyak, L.4
-
73
-
-
0037456823
-
Genetics of gene expression surveyed in maize, mouse and man
-
DOI 10.1038/nature01434
-
Schadt, E. E., Monks, S. A., Drake, T. A. et al. (2003) Genetics of gene expression surveyed in maize, mouse and man. Nature, 422, 297-302. (Pubitemid 36378355)
-
(2003)
Nature
, vol.422
, Issue.6929
, pp. 297-302
-
-
Schadt, E.E.1
Monks, S.A.2
Drake, T.A.3
Lusis, A.J.4
Che, N.5
Colinayo, V.6
Ruff, T.G.7
Milligan, S.B.8
Lamb, J.R.9
Cavet, G.10
Linsley, P.S.11
Mao, M.12
Stoughton, R.B.13
Friend, S.H.14
-
74
-
-
0042856391
-
Trans-acting regulatory variation in Saccharomyces cerevisiae and the role of transcription factors
-
Yvert, G., Brem, R. B., Whittle, J., Akey, J. M., Foss, E., Smith, E. N., Mackelprang, R. and Kruglyak, L. (2003) Trans-acting regulatory variation in Saccharomyces cerevisiae and the role of transcription factors. Nat. Genet., 35, 57-64. (Pubitemid 37048596)
-
(2003)
Nature Genetics
, vol.35
, Issue.1
, pp. 57-64
-
-
Yvert, G.1
Brem, R.B.2
Whittle, J.3
Akey, J.M.4
Foss, E.5
Smith, E.N.6
Mackelprang, R.7
Kruglyak, L.8
-
75
-
-
20144383240
-
Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics'
-
DOI 10.1038/ng1497
-
Bystrykh, L., Weersing, E., Dontje, B. et al. (2005) Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics'. Nat. Genet., 37, 225-232. (Pubitemid 41716249)
-
(2005)
Nature Genetics
, vol.37
, Issue.3
, pp. 225-232
-
-
Bystrykh, L.1
Weersing, E.2
Dontje, B.3
Sutton, S.4
Pletcher, M.T.5
Wiltshire, T.6
Su, A.I.7
Vellenga, E.8
Wang, J.9
Manly, K.F.10
Lu, L.11
Chesler, E.J.12
Alberts, R.13
Jansen, R.C.14
Williams, R.W.15
Cooke, M.P.16
De Haan, G.17
-
76
-
-
20144377218
-
Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease
-
DOI 10.1038/ng1522
-
Hubner, N., Wallace, C. A., Zimdahl, H. et al. (2005) Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease. Nat. Genet., 37, 243-253. (Pubitemid 41716251)
-
(2005)
Nature Genetics
, vol.37
, Issue.3
, pp. 243-253
-
-
Hubner, N.1
Wallace, C.A.2
Zimdahl, H.3
Petretto, E.4
Schulz, H.5
Maciver, F.6
Mueller, M.7
Hummel, O.8
Monti, J.9
Zidek, V.10
Musilova, A.11
Kren, V.12
Causton, H.13
Game, L.14
Born, G.15
Schmidt, S.16
Muller, A.17
Cook, S.A.18
Kurtz, T.W.19
Whittaker, J.20
Pravenec, M.21
Aitman, T.J.22
more..
-
77
-
-
55449096399
-
Genetical genomics: Spotlight on QTL hotspots
-
Breitling, R., Li, Y., Tesson, B. M. et al. (2008) Genetical genomics: spotlight on QTL hotspots. PLo S Genet., 4, e1000232.
-
(2008)
PLo S Genet.
, vol.4
-
-
Breitling, R.1
Li, Y.2
Tesson, B.M.3
-
78
-
-
45149108420
-
Mapping the genetic architecture of gene expression in human liver
-
Schadt, E. E., Molony, C., Chudin, E. et al. (2008) Mapping the genetic architecture of gene expression in human liver. PLo S Biol., 6, e107.
-
(2008)
PLo S Biol.
, vol.6
-
-
Schadt, E.E.1
Molony, C.2
Chudin, E.3
-
79
-
-
8844244726
-
Genetic inheritance of gene expression in human cell lines
-
DOI 10.1086/426461
-
Monks, S. A., Leonardson, A., Zhu, H., Cundiff, P., Pietrusiak, P., Edwards, S., Phillips, J. W., Sachs, A. and Schadt, E. E. (2004) Genetic inheritance ofgene expression in human cell lines. Am. J. Hum. Genet., 75, 1094-1105. (Pubitemid 39532076)
-
(2004)
American Journal of Human Genetics
, vol.75
, Issue.6
, pp. 1094-1105
-
-
Monks, S.A.1
Leonardson, A.2
Zhu, H.3
Cundiff, P.4
Pietrusiak, P.5
Edwards, S.6
Phillips, J.W.7
Sachs, A.8
Schadt, E.E.9
-
80
-
-
55449112185
-
Genome-wide associations of gene expression variation in humans
-
Stranger, B. E., Forrest, M. S., Clark, A. G. et al. (2005) Genome-wide associations of gene expression variation in humans. PLo S Genet., 1, e78.
-
(2005)
PLo S Genet.
, vol.1
-
-
Stranger, B.E.1
Forrest, M.S.2
Clark, A.G.3
-
81
-
-
34548719076
-
Discovery of expression QTLs using large-scale transcriptional profiling in human lymphocytes
-
DOI 10.1038/ng2119, PII NG2119
-
Goring, H. H., Curran, J. E., Johnson, M. P. et al. (2007) Discovery of expression QTLs using large-scale transcriptional profiling in human lymphocytes. Nat. Genet., 39, 1208-1216. (Pubitemid 47482685)
-
(2007)
Nature Genetics
, vol.39
, Issue.10
, pp. 1208-1216
-
-
Goring, H.H.H.1
Curran, J.E.2
Johnson, M.P.3
Dyer, T.D.4
Charlesworth, J.5
Cole, S.A.6
Jowett, J.B.M.7
Abraham, L.J.8
Rainwater, D.L.9
Comuzzie, A.G.10
Mahaney, M.C.11
Almasy, L.12
MacCluer, J.W.13
Kissebah, A.H.14
Collier, G.R.15
Moses, E.K.16
Blangero, J.17
-
82
-
-
41349095280
-
Genetics of gene expression and its effect on disease
-
DOI 10.1038/nature06758, PII NATURE06758
-
Emilsson, V., Thorleifsson, G., Zhang, B. et al. (2008) Genetics of gene expression and its effect on disease. Nature, 452, 423-428. (Pubitemid 351450845)
-
(2008)
Nature
, vol.452
, Issue.7186
, pp. 423-428
-
-
Emilsson, V.1
Thorleifsson, G.2
Zhang, B.3
Leonardson, A.S.4
Zink, F.5
Zhu, J.6
Carlson, S.7
Helgason, A.8
Walters, G.B.9
Gunnarsdottir, S.10
Mouy, M.11
Steinthorsdottir, V.12
Eiriksdottir, G.H.13
Bjornsdottir, G.14
Reynisdottir, I.15
Gudbjartsson, D.16
Helgadottir, A.17
Jonasdottir, A.18
Jonasdottir, A.19
Styrkarsdottir, U.20
Gretarsdottir, S.21
Magnusson, K.P.22
Stefansson, H.23
Fossdal, R.24
Kristjansson, K.25
Gislason, H.G.26
Stefansson, T.27
Leifsson, B.G.28
Thorsteinsdottir, U.29
Lamb, J.R.30
Gulcher, J.R.31
Reitman, M.L.32
Kong, A.33
Schadt, E.E.34
Stefansson, K.35
more..
-
83
-
-
20644454887
-
Genetical genomics in humans and model organisms
-
DOI 10.1016/j.tig.2005.05.004, PII S0168952505001344
-
de Koning, D. J. and Haley, C. S. (2005) Genetical genomics in humans and model organisms. Trends Genet., 21, 377-381. (Pubitemid 40835721)
-
(2005)
Trends in Genetics
, vol.21
, Issue.7
, pp. 377-381
-
-
De Koning, D.-J.1
Haley, C.S.2
-
84
-
-
42549129218
-
From genotype to phenotype: Systems biology meets natural variation
-
DOI 10.1126/science.1153716
-
Benfey, P. N. and Mitchell-Olds, T. (2008) From genotype to phenotype: systems biology meets natural variation. Science, 320, 495-497. (Pubitemid 351590634)
-
(2008)
Science
, vol.320
, Issue.5875
, pp. 495-497
-
-
Benfey, P.N.1
Mitchell-Olds, T.2
-
85
-
-
44949147109
-
Gene set enrichment in e QTL data identifies novel annotations and pathway regulators
-
Wu, C., Delano, D. L., Mitro, N. et al. (2008) Gene set enrichment in e QTL data identifies novel annotations and pathway regulators. PLo S Genet., 4, e1000070.
-
(2008)
PLo S Genet.
, vol.4
-
-
Wu, C.1
Delano, D.L.2
Mitro, N.3
-
86
-
-
45149115741
-
Applying gene expression, proteomics and single-nucleotide polymorphism analysis for complex trait gene identification
-
Stylianou, I. M., Affourtit, J. P., Shockley, K. R., Wilpan, R. Y., Abdi, F. A., Bhardwaj, S., Rollins, J., Churchill, G. A. and Paigen, B. (2008) Applying gene expression, proteomics and single-nucleotide polymorphism analysis for complex trait gene identification. Genetics, 178, 1795-1805.
-
(2008)
Genetics
, vol.178
, pp. 1795-1805
-
-
Stylianou, I.M.1
Affourtit, J.P.2
Shockley, K.R.3
Wilpan, R.Y.4
Abdi, F.A.5
Bhardwaj, S.6
Rollins, J.7
Churchill, G.A.8
Paigen, B.9
-
87
-
-
45149106353
-
Integrating large-scale functional genomic data to dissect the complexity of yeast regulatory networks
-
DOI 10.1038/ng.167, PII NG167
-
Zhu, J., Zhang, B., Smith, E. N., Drees, B., Brem, R. B., Kruglyak, L., Bumgarner, R. E. and Schadt, E. E. (2008) Integrating large-scale functional genomic data to dissect the complexity of yeast regulatory networks. Nat. Genet., 40, 854-861. (Pubitemid 351913653)
-
(2008)
Nature Genetics
, vol.40
, Issue.7
, pp. 854-861
-
-
Zhu, J.1
Zhang, B.2
Smith, E.N.3
Drees, B.4
Brem, R.B.5
Kruglyak, L.6
Bumgarner, R.E.7
Schadt, E.E.8
-
88
-
-
4344673117
-
Uncovering cryptic genetic variation
-
DOI 10.1038/nrg1426
-
Gibson, G. and Dworkin, I. (2004) Uncovering cryptic genetic variation. Nat. Rev. Genet., 5, 681-690. (Pubitemid 39150126)
-
(2004)
Nature Reviews Genetics
, vol.5
, Issue.9
, pp. 681-690
-
-
Gibson, G.1
Dworkin, I.2
-
89
-
-
37649013449
-
Evolutionary potential of hidden genetic variation
-
Le Rouzic, A. and Carlborg, O. (2008) Evolutionary potential of hidden genetic variation. Trends Ecol. Evol., 23, 33-37.
-
(2008)
Trends Ecol. Evol.
, vol.23
, pp. 33-37
-
-
Le Rouzic, A.1
Carlborg, O.2
-
90
-
-
0032569851
-
Hsp90 as a capacitor for morphological evolution
-
DOI 10.1038/24550
-
Rutherford, S. L. and Lindquist, S. (1998) Hsp90 as a capacitor for morphological evolution. Nature, 396, 336-342. (Pubitemid 28557387)
-
(1998)
Nature
, vol.396
, Issue.6709
, pp. 336-342
-
-
Rutherford, S.L.1
Lindquist, S.2
-
91
-
-
0037030713
-
Hsp90 as a capacitor ofphenotypic variation
-
Queitsch, C., Sangster, T. A. and Lindquist, S. (2002) Hsp90 as a capacitor ofphenotypic variation. Nature, 417, 618-624.
-
(2002)
Nature
, vol.417
, pp. 618-624
-
-
Queitsch, C.1
Sangster, T.A.2
Lindquist, S.3
-
92
-
-
0042154192
-
Evolutionary capacitance as a general feature of complex gene networks
-
DOI 10.1038/nature01765
-
Bergman, A. and Siegal, M. L. (2003) Evolutionary capacitance as a general feature of complex gene networks. Nature, 424, 549-552. (Pubitemid 36975775)
-
(2003)
Nature
, vol.424
, Issue.6948
, pp. 549-552
-
-
Bergman, A.1
Siegal, M.L.2
-
93
-
-
36549036104
-
The genetic basis of complex traits: Rare variants or "common gene, common disease"?
-
DOI 10.1385/1-59745-389-7:71, Linkage Disequilibrium and Association Mapping: Analysis and Applications
-
Iyengar, S. K. and Elston, R. C. (2007) The genetic basis of complex traits: rare variants or ''common gene, common disease''? Methods Mol. Biol., 376, 71-84. (Pubitemid 350189861)
-
(2007)
Methods in Molecular Biology
, vol.376
, pp. 71-84
-
-
Iyengar, S.K.1
Elston, R.C.2
-
94
-
-
44349132708
-
Common and rare variants in multifactorial susceptibility to common diseases
-
DOI 10.1038/ng.f.136, PII NGF136
-
Bodmer, W. and Bonilla, C. (2008) Common and rare variants in multifactorial susceptibility to common diseases. Nat. Genet., 40, 695-701. (Pubitemid 351748875)
-
(2008)
Nature Genetics
, vol.40
, Issue.6
, pp. 695-701
-
-
Bodmer, W.1
Bonilla, C.2
|