-
2
-
-
56449123940
-
-
Seow A, Koh WP, Chia KS, Shi LM, Lee HP, Shanmugaratnam KS. Trends in cancer incidence in Singapore 1968-2002. The Singapore Cancer Registry Report No. 6, 2004.
-
Seow A, Koh WP, Chia KS, Shi LM, Lee HP, Shanmugaratnam KS. Trends in cancer incidence in Singapore 1968-2002. The Singapore Cancer Registry Report No. 6, 2004.
-
-
-
-
3
-
-
0030592517
-
Lessons from hereditary colorectal cancer
-
Kinzler K.W., and Vogelstein B. Lessons from hereditary colorectal cancer. Cell 87 (1996) 159-170
-
(1996)
Cell
, vol.87
, pp. 159-170
-
-
Kinzler, K.W.1
Vogelstein, B.2
-
4
-
-
0025339274
-
Hypotheses for the etiology of colorectal cancer-an overview
-
Cheah P.Y. Hypotheses for the etiology of colorectal cancer-an overview. Nutr Cancer 14 (1990) 5-13
-
(1990)
Nutr Cancer
, vol.14
, pp. 5-13
-
-
Cheah, P.Y.1
-
5
-
-
0034644185
-
Environmental and heritable factors in the causation of cancer-analysis of cohorts of twins from Sweden, Denmark and Finland
-
Lichtenstein P., Holm N.V., Verkasalo P.K., et al. Environmental and heritable factors in the causation of cancer-analysis of cohorts of twins from Sweden, Denmark and Finland. N Eng J Med 343 (2000) 78-85
-
(2000)
N Eng J Med
, vol.343
, pp. 78-85
-
-
Lichtenstein, P.1
Holm, N.V.2
Verkasalo, P.K.3
-
6
-
-
0025848680
-
The international collaborative group on hereditary nonpolyposis colorectal cancer
-
Vasen H.F., Mecklin J.P., Khan P.M., and Lynch H.T. The international collaborative group on hereditary nonpolyposis colorectal cancer. Dis Colon Rectum 34 (1991) 424-425
-
(1991)
Dis Colon Rectum
, vol.34
, pp. 424-425
-
-
Vasen, H.F.1
Mecklin, J.P.2
Khan, P.M.3
Lynch, H.T.4
-
7
-
-
0033063711
-
New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the international collaborative group on HNPCC
-
Vasen H.F., Watson P., Mecklin J.P., and Lynch H.T. New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the international collaborative group on HNPCC. Gastroenterology 116 (1999) 1453-1456
-
(1999)
Gastroenterology
, vol.116
, pp. 1453-1456
-
-
Vasen, H.F.1
Watson, P.2
Mecklin, J.P.3
Lynch, H.T.4
-
8
-
-
0031551963
-
A National Cancer Institute workshop on hereditary nonpolyposis colorectal cancer syndrome: meeting highlights and Bethesda guidelines
-
Rodriguez-Bigas M.A., Boland C.R., Hamilton S.R., et al. A National Cancer Institute workshop on hereditary nonpolyposis colorectal cancer syndrome: meeting highlights and Bethesda guidelines. J Natl Cancer Inst 89 (1997) 1758-1762
-
(1997)
J Natl Cancer Inst
, vol.89
, pp. 1758-1762
-
-
Rodriguez-Bigas, M.A.1
Boland, C.R.2
Hamilton, S.R.3
-
9
-
-
0029915034
-
Overview of natural history, pathology, molecular genetics and management of HNPCC (Lynch syndrome)
-
Lynch H.T., Smyrk T., and Lynch J.F. Overview of natural history, pathology, molecular genetics and management of HNPCC (Lynch syndrome). Int J Cancer 69 (1996) 38-43
-
(1996)
Int J Cancer
, vol.69
, pp. 38-43
-
-
Lynch, H.T.1
Smyrk, T.2
Lynch, J.F.3
-
10
-
-
0032555020
-
Incidence of hereditary nonpolyposis colorectal cancer and the feasibility of molecular screening for the disease
-
Aaltonen L.A., Salovaara R., Kristo P., et al. Incidence of hereditary nonpolyposis colorectal cancer and the feasibility of molecular screening for the disease. N Engl J Med 338 (1998) 1481-1487
-
(1998)
N Engl J Med
, vol.338
, pp. 1481-1487
-
-
Aaltonen, L.A.1
Salovaara, R.2
Kristo, P.3
-
11
-
-
0027158031
-
Clues to the pathogenesis of familial colorectal cancer
-
Aaltonen L.A., Petlomaki P., Leach F., et al. Clues to the pathogenesis of familial colorectal cancer. Science 26 (1993) 812-816
-
(1993)
Science
, vol.26
, pp. 812-816
-
-
Aaltonen, L.A.1
Petlomaki, P.2
Leach, F.3
-
12
-
-
0028226295
-
Replication errors in benign and malignant tumors from hereditary nonpolyposis colorectal cancer patients
-
Aaltonen L.A., Petlomaki P., Mecklin J.P., et al. Replication errors in benign and malignant tumors from hereditary nonpolyposis colorectal cancer patients. Cancer Res 54 (1994) 1645-1648
-
(1994)
Cancer Res
, vol.54
, pp. 1645-1648
-
-
Aaltonen, L.A.1
Petlomaki, P.2
Mecklin, J.P.3
-
13
-
-
0027145633
-
Mutation of a mut S homolog in hereditary nonpolyposis colorectal cancer
-
Leach F.S., Nicolaides N.C., Papadopoulos N., et al. Mutation of a mut S homolog in hereditary nonpolyposis colorectal cancer. Cell 75 (1993) 1215-1225
-
(1993)
Cell
, vol.75
, pp. 1215-1225
-
-
Leach, F.S.1
Nicolaides, N.C.2
Papadopoulos, N.3
-
14
-
-
0028221943
-
Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with HNPCC
-
Bronner C.E., Baker S.M., Morrison P.T., et al. Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with HNPCC. Nature 368 (1994) 258-261
-
(1994)
Nature
, vol.368
, pp. 258-261
-
-
Bronner, C.E.1
Baker, S.M.2
Morrison, P.T.3
-
15
-
-
0028350601
-
Mutation of a mut L homolog in hereditary colon cancer
-
Papadopoulos N., Nidolaides N.C., Wei Y.F., et al. Mutation of a mut L homolog in hereditary colon cancer. Science 263 (1994) 1625-1629
-
(1994)
Science
, vol.263
, pp. 1625-1629
-
-
Papadopoulos, N.1
Nidolaides, N.C.2
Wei, Y.F.3
-
16
-
-
0037390446
-
The hereditary nonpolyposis colorectal cancer syndrome: genetics and clinical implications
-
Chung D.C., and Rustgi A.K. The hereditary nonpolyposis colorectal cancer syndrome: genetics and clinical implications. Ann Intern Med 138 (2003) 560-570
-
(2003)
Ann Intern Med
, vol.138
, pp. 560-570
-
-
Chung, D.C.1
Rustgi, A.K.2
-
17
-
-
0031017268
-
Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines
-
Kane M.F., Loda M., Gaida G.M., et al. Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines. Cancer Res 57 (1997) 808-811
-
(1997)
Cancer Res
, vol.57
, pp. 808-811
-
-
Kane, M.F.1
Loda, M.2
Gaida, G.M.3
-
18
-
-
13144266670
-
Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma
-
Herman J.G., Umar A., Polyak K., et al. Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma. Proc Nat Acad Sci USA 95 (1998) 6870-6875
-
(1998)
Proc Nat Acad Sci USA
, vol.95
, pp. 6870-6875
-
-
Herman, J.G.1
Umar, A.2
Polyak, K.3
-
19
-
-
33749122904
-
Heritable germline epimutation of MSH2 in a family with hereditary nonpolyposis colorectal cancer
-
Chan T.L., Yuen S.T., Kong C.K., et al. Heritable germline epimutation of MSH2 in a family with hereditary nonpolyposis colorectal cancer. Nat Genet 38 (2006) 1178-1183
-
(2006)
Nat Genet
, vol.38
, pp. 1178-1183
-
-
Chan, T.L.1
Yuen, S.T.2
Kong, C.K.3
-
20
-
-
0027933070
-
Mutations of two PMS homologues in hereditary nonpolyposis colorectal cancer
-
Nicolaides N.C., Papadopoulos N., Liu B., et al. Mutations of two PMS homologues in hereditary nonpolyposis colorectal cancer. Nature 371 (1994) 75-80
-
(1994)
Nature
, vol.371
, pp. 75-80
-
-
Nicolaides, N.C.1
Papadopoulos, N.2
Liu, B.3
-
21
-
-
0031278322
-
Germline mutation of MSH6 as the cause of hereditary nonpolyposis colorectal cancer
-
Miyaki M., Konishi M., Tanaka K., et al. Germline mutation of MSH6 as the cause of hereditary nonpolyposis colorectal cancer. Nat Genet 17 (1997) 271-272
-
(1997)
Nat Genet
, vol.17
, pp. 271-272
-
-
Miyaki, M.1
Konishi, M.2
Tanaka, K.3
-
22
-
-
0030870631
-
Germline mutation of the hMSH6/GTBP gene in an atypical hereditary nonpolyposis colorectal cancer kindred
-
Akiyama Y., Sato H., Yamada T., et al. Germline mutation of the hMSH6/GTBP gene in an atypical hereditary nonpolyposis colorectal cancer kindred. Cancer Res 57 (1997) 3920-3923
-
(1997)
Cancer Res
, vol.57
, pp. 3920-3923
-
-
Akiyama, Y.1
Sato, H.2
Yamada, T.3
-
23
-
-
3242670404
-
Cancer risk in hereditary nonpolyposis colorectal cancer due to MSH6 mutations: impact on counseling and surveillance
-
Hendriks Y.M.C., Wagner A., Morreau H., et al. Cancer risk in hereditary nonpolyposis colorectal cancer due to MSH6 mutations: impact on counseling and surveillance. Gastroenterology 127 (2004) 17-25
-
(2004)
Gastroenterology
, vol.127
, pp. 17-25
-
-
Hendriks, Y.M.C.1
Wagner, A.2
Morreau, H.3
-
24
-
-
3142682207
-
A genotype-phenotype correlation in HNPCC: strong predominance of msh2 mutations in 41 patients with Muir-Torre syndrome
-
Mangold E., Pagenstecher C., Leister M., et al. A genotype-phenotype correlation in HNPCC: strong predominance of msh2 mutations in 41 patients with Muir-Torre syndrome. J Med Genet 41 (2004) 567-572
-
(2004)
J Med Genet
, vol.41
, pp. 567-572
-
-
Mangold, E.1
Pagenstecher, C.2
Leister, M.3
-
25
-
-
39649093644
-
The frequency of Muir-Torre syndrome among Lynch syndrome families
-
South C.D., Hampel H., Comerars I., Westman J.A., Frankel W.L., and de la Chapelle A. The frequency of Muir-Torre syndrome among Lynch syndrome families. J Natl Cancer Inst 100 (2008) 277-281
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 277-281
-
-
South, C.D.1
Hampel, H.2
Comerars, I.3
Westman, J.A.4
Frankel, W.L.5
de la Chapelle, A.6
-
26
-
-
0025938038
-
Identification and characterization of the familial adenomatous polyposis coli gene
-
Groden J., Thliveris A., Samowitz W., et al. Identification and characterization of the familial adenomatous polyposis coli gene. Cell 66 (1991) 589-600
-
(1991)
Cell
, vol.66
, pp. 589-600
-
-
Groden, J.1
Thliveris, A.2
Samowitz, W.3
-
27
-
-
0025941471
-
Identification of deletion mutations and three new genes at the familial polyposis locus
-
Joslyn G., Carlson N., Thliveris A., et al. Identification of deletion mutations and three new genes at the familial polyposis locus. Cell 66 (1991) 600-613
-
(1991)
Cell
, vol.66
, pp. 600-613
-
-
Joslyn, G.1
Carlson, N.2
Thliveris, A.3
-
28
-
-
0025817880
-
Identification of FAP locus genes from chromosome 5q21
-
Kinzler K.W., Nilbert M.C., Su L.K., et al. Identification of FAP locus genes from chromosome 5q21. Science 253 (1991) 661-665
-
(1991)
Science
, vol.253
, pp. 661-665
-
-
Kinzler, K.W.1
Nilbert, M.C.2
Su, L.K.3
-
29
-
-
0029928160
-
APC gene: database of germline and somatic mutations in human tumors and cell lines
-
Beroud C., and Soussi T. APC gene: database of germline and somatic mutations in human tumors and cell lines. Nucleic Acids Res 24 (1996) 121-124
-
(1996)
Nucleic Acids Res
, vol.24
, pp. 121-124
-
-
Beroud, C.1
Soussi, T.2
-
30
-
-
0033999318
-
APC mutation and phenotypic spectrum of Singapore familial adenomatous polyposis patients
-
Cao X., Eu K.W., Seow-Choen F., Zhao Y., and Cheah P.Y. APC mutation and phenotypic spectrum of Singapore familial adenomatous polyposis patients. Eur J Hum Genet 8 (2000) 42-48
-
(2000)
Eur J Hum Genet
, vol.8
, pp. 42-48
-
-
Cao, X.1
Eu, K.W.2
Seow-Choen, F.3
Zhao, Y.4
Cheah, P.Y.5
-
31
-
-
18344367618
-
Whole-gene APC deletions cause classical familial adenomatous polyposis, but not attenuated polyposis or "multiple" colorectal adenomas
-
Sieber O.M., Lamlum H., Crabree M.D., et al. Whole-gene APC deletions cause classical familial adenomatous polyposis, but not attenuated polyposis or "multiple" colorectal adenomas. Proc Natl Acad Sci USA 99 (2002) 2954-2958
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 2954-2958
-
-
Sieber, O.M.1
Lamlum, H.2
Crabree, M.D.3
-
32
-
-
4444266965
-
First genotype characterization of Argentinean FAP patients: identification of 14 novel APC mutations
-
De Rosa M., Dourisboure R.J., Morelli G., et al. First genotype characterization of Argentinean FAP patients: identification of 14 novel APC mutations. Hum Mut 23 (2004) 523-524
-
(2004)
Hum Mut
, vol.23
, pp. 523-524
-
-
De Rosa, M.1
Dourisboure, R.J.2
Morelli, G.3
-
33
-
-
13444253746
-
Large deletions of the APC gene in 15% of mutation-negative patients with classical polyposis (FAP): a Belgian study
-
Michils G., Tejpar S., Thoelen R., et al. Large deletions of the APC gene in 15% of mutation-negative patients with classical polyposis (FAP): a Belgian study. Hum Mut 25 (2005) 125-134
-
(2005)
Hum Mut
, vol.25
, pp. 125-134
-
-
Michils, G.1
Tejpar, S.2
Thoelen, R.3
-
34
-
-
13444311812
-
Large submicroscopic genomic APC deletions are a common cause of typical familial adenomatous polyposis
-
Aretz S., Stienen D., Uhlhaas S., et al. Large submicroscopic genomic APC deletions are a common cause of typical familial adenomatous polyposis. J Med Genet 42 (2005) 185-192
-
(2005)
J Med Genet
, vol.42
, pp. 185-192
-
-
Aretz, S.1
Stienen, D.2
Uhlhaas, S.3
-
36
-
-
33845408501
-
Singapore familial adenomatous polyposis (FAP) patients with classical adenomatous polyposis but undetectable APC mutations have accelerated cancer progression
-
Cao X., Hong Y., Eu K.W., Loi C., and Cheah P.Y. Singapore familial adenomatous polyposis (FAP) patients with classical adenomatous polyposis but undetectable APC mutations have accelerated cancer progression. Am J Gastroenterol 101 (2006) 2810-2817
-
(2006)
Am J Gastroenterol
, vol.101
, pp. 2810-2817
-
-
Cao, X.1
Hong, Y.2
Eu, K.W.3
Loi, C.4
Cheah, P.Y.5
-
37
-
-
0035076731
-
Can APC mutation analysis contribute to therapeutic decisions in familial adenomatous polyposis? Experience from 680 FAP families
-
Friedl W., Caspari R., Sengteller M., et al. Can APC mutation analysis contribute to therapeutic decisions in familial adenomatous polyposis? Experience from 680 FAP families. Gut 48 (2001) 515-521
-
(2001)
Gut
, vol.48
, pp. 515-521
-
-
Friedl, W.1
Caspari, R.2
Sengteller, M.3
-
38
-
-
33846074011
-
Correlations between mutation site in APC and phenotype of familial adenomatous polyposis (FAP): a review of the literature
-
Nieuwenhuis M.H., and Vasen H.F.A. Correlations between mutation site in APC and phenotype of familial adenomatous polyposis (FAP): a review of the literature. Crit Rev Oncol/Hematol 61 (2007) 153-161
-
(2007)
Crit Rev Oncol/Hematol
, vol.61
, pp. 153-161
-
-
Nieuwenhuis, M.H.1
Vasen, H.F.A.2
-
39
-
-
0030949463
-
Activation of β-catenin-Tcf signaling in colon cancer by mutations in β-catenin or APC
-
Morin P.J., Sparks A.B., Korinek V., et al. Activation of β-catenin-Tcf signaling in colon cancer by mutations in β-catenin or APC. Science 275 (1997) 1787-1790
-
(1997)
Science
, vol.275
, pp. 1787-1790
-
-
Morin, P.J.1
Sparks, A.B.2
Korinek, V.3
-
40
-
-
0031888098
-
β-catenin: a key mediator of Wnt signaling
-
Willert K., and Nusse R. β-catenin: a key mediator of Wnt signaling. Curr Opin Genet Dev 8 (1998) 95-102
-
(1998)
Curr Opin Genet Dev
, vol.8
, pp. 95-102
-
-
Willert, K.1
Nusse, R.2
-
41
-
-
0345211599
-
Germline mutations are frequent in the APC gene but absent in β-catenin gene in familial adenomatous polyposis patients.
-
Cao X., Eu K.W., Seow-Choen F., and Cheah P.Y. Germline mutations are frequent in the APC gene but absent in β-catenin gene in familial adenomatous polyposis patients. Genes Chromosomes Cancer 25 (1999) 396-398
-
(1999)
Genes Chromosomes Cancer
, vol.25
, pp. 396-398
-
-
Cao, X.1
Eu, K.W.2
Seow-Choen, F.3
Cheah, P.Y.4
-
42
-
-
0033005692
-
Germline mutations in the β-catenin gene are not associated with the FAP phenotype without an APC mutation
-
Dobbie Z., and Muller H. Germline mutations in the β-catenin gene are not associated with the FAP phenotype without an APC mutation. J Med Genet 36 (1999) 573-574
-
(1999)
J Med Genet
, vol.36
, pp. 573-574
-
-
Dobbie, Z.1
Muller, H.2
-
43
-
-
0035496104
-
APC, signal transduction and genetic instability in colorectal cancer
-
Fodde R., Smits R., and Clever H. APC, signal transduction and genetic instability in colorectal cancer. Nat Rev Cancer 1 (2001) 55-67
-
(2001)
Nat Rev Cancer
, vol.1
, pp. 55-67
-
-
Fodde, R.1
Smits, R.2
Clever, H.3
-
45
-
-
3342929410
-
Genetic conditions associated with intestinal juvenile polyps
-
Merg A., and Howe J.R. Genetic conditions associated with intestinal juvenile polyps. Am J Med Genet 129C (2004) 44-55
-
(2004)
Am J Med Genet
, vol.129 C
, pp. 44-55
-
-
Merg, A.1
Howe, J.R.2
-
46
-
-
0032524069
-
Mutations in the SMAD4/DPC4 gene in juvenile polyposis
-
Howe J.R., Roth S., Ringold J.C., et al. Mutations in the SMAD4/DPC4 gene in juvenile polyposis. Science 280 (1998) 1086-1088
-
(1998)
Science
, vol.280
, pp. 1086-1088
-
-
Howe, J.R.1
Roth, S.2
Ringold, J.C.3
-
47
-
-
0032771825
-
Frequent 4-bp deletion in exon 9 of the SMAD4/MADH4 gene in familial juvenile polyposis patients
-
Friedl W., Kruse R., Uhlhaas S., et al. Frequent 4-bp deletion in exon 9 of the SMAD4/MADH4 gene in familial juvenile polyposis patients. Genes Chromosomes Cancer 25 (1999) 403-406
-
(1999)
Genes Chromosomes Cancer
, vol.25
, pp. 403-406
-
-
Friedl, W.1
Kruse, R.2
Uhlhaas, S.3
-
48
-
-
0034194138
-
Allelic loss at SMAD4 in polyps from juvenile polyposis patients and use of fluorescence in situ hybridization to demonstrate clonal origin of the epithelium
-
Woodford-Richens K., Williamson J., Bevan S., et al. Allelic loss at SMAD4 in polyps from juvenile polyposis patients and use of fluorescence in situ hybridization to demonstrate clonal origin of the epithelium. Cancer Res 60 (2000) 2477-2482
-
(2000)
Cancer Res
, vol.60
, pp. 2477-2482
-
-
Woodford-Richens, K.1
Williamson, J.2
Bevan, S.3
-
49
-
-
0034972978
-
Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis
-
Howe J.R., Bair J.L., Sayed M.G., et al. Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis. Nat Genet 28 (2001) 184-187
-
(2001)
Nat Genet
, vol.28
, pp. 184-187
-
-
Howe, J.R.1
Bair, J.L.2
Sayed, M.G.3
-
50
-
-
0034829630
-
Germline mutations in BMPR1A/ALK3 cause a subset of cases of juvenile polyposis syndrome and of Cowden and Bannayan-Riley-Ruvalcaba syndromes
-
Zhou X., Woodford-Richens K., Lehtonen R., et al. Germline mutations in BMPR1A/ALK3 cause a subset of cases of juvenile polyposis syndrome and of Cowden and Bannayan-Riley-Ruvalcaba syndromes. Am J Hum Genet 69 (2001) 704-711
-
(2001)
Am J Hum Genet
, vol.69
, pp. 704-711
-
-
Zhou, X.1
Woodford-Richens, K.2
Lehtonen, R.3
-
51
-
-
0036664427
-
Juvenile polyposis:massive gastric polyposis is more common in MADH4 mutation carriers than in BMPR1A mutation carriers
-
Friedl W., Uhlhaas S., Schulmann K., et al. Juvenile polyposis:massive gastric polyposis is more common in MADH4 mutation carriers than in BMPR1A mutation carriers. Hum Genet 111 (2002) 108-111
-
(2002)
Hum Genet
, vol.111
, pp. 108-111
-
-
Friedl, W.1
Uhlhaas, S.2
Schulmann, K.3
-
52
-
-
36348937214
-
High proportion of large genomic deletions and genotype-phenotype update in 80 unrelated families with Juvenile Polyposis syndrome
-
Aretz S., Stienen D., Uhlhaas S., et al. High proportion of large genomic deletions and genotype-phenotype update in 80 unrelated families with Juvenile Polyposis syndrome. J Med Genet 44 (2007) 702-709
-
(2007)
J Med Genet
, vol.44
, pp. 702-709
-
-
Aretz, S.1
Stienen, D.2
Uhlhaas, S.3
-
53
-
-
27744511296
-
Molecular classification of patients with unexplained hamartomatous and hyperplastic polyposis
-
Sweet K., Willis J., Zhou X., et al. Molecular classification of patients with unexplained hamartomatous and hyperplastic polyposis. JAMA 294 (2005) 2465-2473
-
(2005)
JAMA
, vol.294
, pp. 2465-2473
-
-
Sweet, K.1
Willis, J.2
Zhou, X.3
-
54
-
-
28844507521
-
High proportion of large genomic STK11 deletions in Peutz-Jeghers syndrome
-
Aretz S., Stienen D., Uhlhaas S., et al. High proportion of large genomic STK11 deletions in Peutz-Jeghers syndrome. Hum Mut 26 (2005) 513-519
-
(2005)
Hum Mut
, vol.26
, pp. 513-519
-
-
Aretz, S.1
Stienen, D.2
Uhlhaas, S.3
-
55
-
-
33745966059
-
LKB1 exonic and whole gene deletions are a common cause of Peutz-Jeghers syndrome
-
Volikos E., Robinson J., Aittomaki K., et al. LKB1 exonic and whole gene deletions are a common cause of Peutz-Jeghers syndrome. J Med Genet 43 (2006) e18
-
(2006)
J Med Genet
, vol.43
-
-
Volikos, E.1
Robinson, J.2
Aittomaki, K.3
-
56
-
-
36248948056
-
Genetic defects underlying Peutz-Jeghers syndrome (PJS) and exclusion of the polarity-associated MARK/Par1 gene family as potential PJS candidates
-
de Leng W.W., Jansen M., Carvalho R., et al. Genetic defects underlying Peutz-Jeghers syndrome (PJS) and exclusion of the polarity-associated MARK/Par1 gene family as potential PJS candidates. Clin Genet 72 (2007) 568-573
-
(2007)
Clin Genet
, vol.72
, pp. 568-573
-
-
de Leng, W.W.1
Jansen, M.2
Carvalho, R.3
-
57
-
-
0031004088
-
Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome
-
Liaw D., Marsh D.J., Li J., et al. Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome. Nat Genet 16 (1997) 64-67
-
(1997)
Nat Genet
, vol.16
, pp. 64-67
-
-
Liaw, D.1
Marsh, D.J.2
Li, J.3
-
58
-
-
31544454967
-
PTEN autoregulates its expression by stabilization of p53 in a phosphatase-independent manner
-
Tang Y., and Eng C. PTEN autoregulates its expression by stabilization of p53 in a phosphatase-independent manner. Cancer Res 66 (2006) 736-742
-
(2006)
Cancer Res
, vol.66
, pp. 736-742
-
-
Tang, Y.1
Eng, C.2
-
59
-
-
0031048855
-
Clinical and molecular features of the hereditary mixed polyposis syndrome
-
Whitelaw S.C., Murday V.A., Tomlinson I.P., et al. Clinical and molecular features of the hereditary mixed polyposis syndrome. Gastroenterology 112 (1997) 327-334
-
(1997)
Gastroenterology
, vol.112
, pp. 327-334
-
-
Whitelaw, S.C.1
Murday, V.A.2
Tomlinson, I.P.3
-
60
-
-
0037730140
-
An acenstral Ashkenazi haplotype at the HMPS/CRAC1 locus on 15q13-q14 is associated with hereditary mixed polyposis syndrome
-
Jaeger E.E.M., Woodford-Richens K.L., Lockett M., et al. An acenstral Ashkenazi haplotype at the HMPS/CRAC1 locus on 15q13-q14 is associated with hereditary mixed polyposis syndrome. Am J Hum Genet 72 (2003) 1261-1267
-
(2003)
Am J Hum Genet
, vol.72
, pp. 1261-1267
-
-
Jaeger, E.E.M.1
Woodford-Richens, K.L.2
Lockett, M.3
-
61
-
-
37549072226
-
Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13.3 influence colorectal cancer risk
-
Jaeger E., Webb E., Howarth K., et al. Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13.3 influence colorectal cancer risk. Nat Genet 40 (2008) 26-28
-
(2008)
Nat Genet
, vol.40
, pp. 26-28
-
-
Jaeger, E.1
Webb, E.2
Howarth, K.3
-
62
-
-
33746806391
-
Mapping of hereditary mixed polyposis syndrome (HMPS) to chromosome 10q23 by genomewide high-density single nucleotide polymorphism (SNP) scan and identification of BMPR1A loss of function
-
Cao X., Eu K.W., Kumarasinghe M.P., Li H.H., Loi C., and Cheah P.Y. Mapping of hereditary mixed polyposis syndrome (HMPS) to chromosome 10q23 by genomewide high-density single nucleotide polymorphism (SNP) scan and identification of BMPR1A loss of function. J Med Genet 43 (2006) e13
-
(2006)
J Med Genet
, vol.43
-
-
Cao, X.1
Eu, K.W.2
Kumarasinghe, M.P.3
Li, H.H.4
Loi, C.5
Cheah, P.Y.6
-
64
-
-
0036478899
-
Inherited variants of MYH associated with somatic G:C to T:A mutations in colorectal tumors
-
Al-Tassan N., Chmiel N.H., Maynard J., et al. Inherited variants of MYH associated with somatic G:C to T:A mutations in colorectal tumors. Nat Genet 30 (2002) 227-232
-
(2002)
Nat Genet
, vol.30
, pp. 227-232
-
-
Al-Tassan, N.1
Chmiel, N.H.2
Maynard, J.3
-
65
-
-
0038501052
-
Autosomal recessive colorectal adenomatous polyposis due to inherited mutations of MYH
-
Sampson J.R., Dolwani S., Jones S., et al. Autosomal recessive colorectal adenomatous polyposis due to inherited mutations of MYH. Lancet 362 (2003) 39-41
-
(2003)
Lancet
, vol.362
, pp. 39-41
-
-
Sampson, J.R.1
Dolwani, S.2
Jones, S.3
-
66
-
-
0037468517
-
Multiple colorectal adenomas, classic adenomatous polyposis, and germ-line mutations in MYH
-
Sieber O.M., Lipton L., Crabtree M., et al. Multiple colorectal adenomas, classic adenomatous polyposis, and germ-line mutations in MYH. N Engl J Med 348 (2003) 791-799
-
(2003)
N Engl J Med
, vol.348
, pp. 791-799
-
-
Sieber, O.M.1
Lipton, L.2
Crabtree, M.3
-
67
-
-
3242689475
-
MYH mutations in patients with attenuated and classic polyposis and with young-onset colorectal cancer without polyps
-
Wang L., Baudhun L.M., Boardman L.A., et al. MYH mutations in patients with attenuated and classic polyposis and with young-onset colorectal cancer without polyps. Gastroenterology 127 (2004) 9-16
-
(2004)
Gastroenterology
, vol.127
, pp. 9-16
-
-
Wang, L.1
Baudhun, L.M.2
Boardman, L.A.3
-
68
-
-
33947280508
-
Identification of MYH mutation carriers in colorectal cancer: a multicenter, case-control, population-based study
-
Balaguer F., Castellvi-Bel S., Castells A., et al. Identification of MYH mutation carriers in colorectal cancer: a multicenter, case-control, population-based study. Clin Gastroenterol Hepatol 5 (2007) 379-387
-
(2007)
Clin Gastroenterol Hepatol
, vol.5
, pp. 379-387
-
-
Balaguer, F.1
Castellvi-Bel, S.2
Castells, A.3
-
69
-
-
10744220394
-
Carcinogenesis in MYH-associated polyposis follows a distinct genetic pathway
-
Lipton L., Halford S.E., Johnson V., et al. Carcinogenesis in MYH-associated polyposis follows a distinct genetic pathway. Cancer Res 63 (2003) 7595-7599
-
(2003)
Cancer Res
, vol.63
, pp. 7595-7599
-
-
Lipton, L.1
Halford, S.E.2
Johnson, V.3
-
70
-
-
11144355687
-
Role of inherited defects of MYH in the development of sporadic colorectal cancer
-
Kambara T., Whitehall V.L., Spring K.J., et al. Role of inherited defects of MYH in the development of sporadic colorectal cancer. Genes Chromosomes Cancer 40 (2004) 1-9
-
(2004)
Genes Chromosomes Cancer
, vol.40
, pp. 1-9
-
-
Kambara, T.1
Whitehall, V.L.2
Spring, K.J.3
-
71
-
-
20544452084
-
Germline susceptibility to colorectal cancer due to a base-excision repair gene defects
-
Farrington S.M., Tenesa A., Barnetson R., et al. Germline susceptibility to colorectal cancer due to a base-excision repair gene defects. Am J Hum Genet 77 (2005) 112-119
-
(2005)
Am J Hum Genet
, vol.77
, pp. 112-119
-
-
Farrington, S.M.1
Tenesa, A.2
Barnetson, R.3
-
72
-
-
33749003995
-
Colorectal cancer risk in monoallelic carriers of MYH variants
-
Webb E.L., Rudd M.F., and Houlston R.S. Colorectal cancer risk in monoallelic carriers of MYH variants. Am J Hum Genet 79 (2006) 768-771
-
(2006)
Am J Hum Genet
, vol.79
, pp. 768-771
-
-
Webb, E.L.1
Rudd, M.F.2
Houlston, R.S.3
-
73
-
-
33750519632
-
The case for a genetic predisposition to serrated neoplasia in the colorectum: hypothesis and review of the literature
-
Young J., and Jass J.R. The case for a genetic predisposition to serrated neoplasia in the colorectum: hypothesis and review of the literature. Cancer Epidemiol Biomarkers Prev 15 (2006) 1778-1784
-
(2006)
Cancer Epidemiol Biomarkers Prev
, vol.15
, pp. 1778-1784
-
-
Young, J.1
Jass, J.R.2
-
74
-
-
35348992639
-
The genetics of hereditary colon cancer
-
Rustgi A.K. The genetics of hereditary colon cancer. Genes Dev 21 (2007) 2525-2538
-
(2007)
Genes Dev
, vol.21
, pp. 2525-2538
-
-
Rustgi, A.K.1
-
75
-
-
33845608798
-
Classification of colorectal cancer based on correlation of clinical, morphological and molecular features
-
Jass J.R. Classification of colorectal cancer based on correlation of clinical, morphological and molecular features. Histopathology 50 (2007) 113-130
-
(2007)
Histopathology
, vol.50
, pp. 113-130
-
-
Jass, J.R.1
-
76
-
-
0034909923
-
Polymorphisms and colorectal tumour risk
-
Houlston R.S., and Tomlinson I.P.M. Polymorphisms and colorectal tumour risk. Gastroenterology 121 (2001) 282-301
-
(2001)
Gastroenterology
, vol.121
, pp. 282-301
-
-
Houlston, R.S.1
Tomlinson, I.P.M.2
-
77
-
-
8644235804
-
Multiple rare variants in different genes account for multifactorial inherited susceptibility to colorectal adenomas
-
Fearnhead N.S., Wilding J.L., Winney B., et al. Multiple rare variants in different genes account for multifactorial inherited susceptibility to colorectal adenomas. Proc Natl Acad Sci USA 101 (2004) 15992-15997
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 15992-15997
-
-
Fearnhead, N.S.1
Wilding, J.L.2
Winney, B.3
-
78
-
-
25444443671
-
Rare variant hypothesis for multifactorial inheritance: susceptibility to colorectal adenomas as a model
-
Fearnhead N.S., Winney B., and Bodmer W.F. Rare variant hypothesis for multifactorial inheritance: susceptibility to colorectal adenomas as a model. Cell Cycle 4 (2005) 521-525
-
(2005)
Cell Cycle
, vol.4
, pp. 521-525
-
-
Fearnhead, N.S.1
Winney, B.2
Bodmer, W.F.3
-
79
-
-
33744973579
-
Cancer genetics: colorectal cancer as a model
-
Bodmer W.F. Cancer genetics: colorectal cancer as a model. J Hum Genet 51 (2006) 391-396
-
(2006)
J Hum Genet
, vol.51
, pp. 391-396
-
-
Bodmer, W.F.1
-
80
-
-
39049097331
-
Multiple rare nonsynonymus variants in the Adenomatous polyposis coli gene predispose to colorectal adenomas
-
Azzopardi D., Dallosso A.R., Eliason K., et al. Multiple rare nonsynonymus variants in the Adenomatous polyposis coli gene predispose to colorectal adenomas. Cancer Res 68 (2008) 358-363
-
(2008)
Cancer Res
, vol.68
, pp. 358-363
-
-
Azzopardi, D.1
Dallosso, A.R.2
Eliason, K.3
-
81
-
-
34548863628
-
Influence of methylenetetrahydrofolate reductase gene polymorphisms C677T and A1298C on age-associated risk for colorectal cancer in a caucasian lynch syndrome population
-
Pande M., Chen J., Amos C.I., Lynch P.M., Broaddus R., and Frazier M.L. Influence of methylenetetrahydrofolate reductase gene polymorphisms C677T and A1298C on age-associated risk for colorectal cancer in a caucasian lynch syndrome population. Cancer Epidemiol biomarkers Prev 16 (2007) 1753-1759
-
(2007)
Cancer Epidemiol biomarkers Prev
, vol.16
, pp. 1753-1759
-
-
Pande, M.1
Chen, J.2
Amos, C.I.3
Lynch, P.M.4
Broaddus, R.5
Frazier, M.L.6
-
82
-
-
34249951407
-
Polymorphisms in methylenetetrahydrofolate reductase gene (MTHFR) and the age of onset of sporadic colorectal adenocarcinoma
-
Lima C.S., Nascimento H., Bonadia L.C., et al. Polymorphisms in methylenetetrahydrofolate reductase gene (MTHFR) and the age of onset of sporadic colorectal adenocarcinoma. Int J Colorectal Dis 22 (2007) 757-763
-
(2007)
Int J Colorectal Dis
, vol.22
, pp. 757-763
-
-
Lima, C.S.1
Nascimento, H.2
Bonadia, L.C.3
-
83
-
-
0034650542
-
Effects of cyclin 1D polymorphism on age of onset of hereditary nonpolyposis colorectal cancer
-
Kong S., Amos C.I., Luthra R., Lynch P.M., Levin B., and Frazier M.L. Effects of cyclin 1D polymorphism on age of onset of hereditary nonpolyposis colorectal cancer. Cancer Res 60 (2000) 249-252
-
(2000)
Cancer Res
, vol.60
, pp. 249-252
-
-
Kong, S.1
Amos, C.I.2
Luthra, R.3
Lynch, P.M.4
Levin, B.5
Frazier, M.L.6
-
84
-
-
85047697181
-
Contribution of cyclin D1 (CCND1) and E-cadherin (CDH1) polymorphisms to familial and sporadic colorectal cancer
-
Porter T.R., Richards F.M., Houlston R.S., et al. Contribution of cyclin D1 (CCND1) and E-cadherin (CDH1) polymorphisms to familial and sporadic colorectal cancer. Oncogene 21 (2002) 1928-1933
-
(2002)
Oncogene
, vol.21
, pp. 1928-1933
-
-
Porter, T.R.1
Richards, F.M.2
Houlston, R.S.3
-
85
-
-
0035881875
-
Cyclin D1 as a genetic modifier in hereditary nonpolyposis colorectal cancer
-
Bala S., and Petlomaki P. Cyclin D1 as a genetic modifier in hereditary nonpolyposis colorectal cancer. Cancer Res 61 (2001) 6042-6045
-
(2001)
Cancer Res
, vol.61
, pp. 6042-6045
-
-
Bala, S.1
Petlomaki, P.2
-
86
-
-
0345098458
-
Association of the cylcin D1 A870G polymorphism with advanced colorectal cancer
-
Le Marchand L., Seifried A., Lum-Jones A., Donlon T., and Wilkens L.R. Association of the cylcin D1 A870G polymorphism with advanced colorectal cancer. JAMA 290 (2003) 2843-2848
-
(2003)
JAMA
, vol.290
, pp. 2843-2848
-
-
Le Marchand, L.1
Seifried, A.2
Lum-Jones, A.3
Donlon, T.4
Wilkens, L.R.5
-
87
-
-
0346995274
-
Polymorphism of the cyclin D1 gene, CCND1, and risk for incident sporadic colorectal adenomas
-
Lewis R.C., Bostick R.M., Xie D., et al. Polymorphism of the cyclin D1 gene, CCND1, and risk for incident sporadic colorectal adenomas. Cancer Res 63 (2003) 8549-8553
-
(2003)
Cancer Res
, vol.63
, pp. 8549-8553
-
-
Lewis, R.C.1
Bostick, R.M.2
Xie, D.3
-
88
-
-
18044375792
-
The GG genotype of cyclin D1 G870A polymorphism is associated with increased risk and advanced colorectal cancer in Singapore patients
-
Hong Y., Eu K.W., Seow-Choen F., Fook-Chong S., and Cheah P.Y. The GG genotype of cyclin D1 G870A polymorphism is associated with increased risk and advanced colorectal cancer in Singapore patients. Eur J Cancer 41 (2005) 1037-1044
-
(2005)
Eur J Cancer
, vol.41
, pp. 1037-1044
-
-
Hong, Y.1
Eu, K.W.2
Seow-Choen, F.3
Fook-Chong, S.4
Cheah, P.Y.5
-
89
-
-
33646510881
-
Absence of association between cyclin D1 (CCND1) G870A polymorphism and age of onset in hereditary nonpolyposis colorectal cancer
-
Kruger S., Engel C., Bier A., et al. Absence of association between cyclin D1 (CCND1) G870A polymorphism and age of onset in hereditary nonpolyposis colorectal cancer. Cancer Lett 236 (2006) 191-197
-
(2006)
Cancer Lett
, vol.236
, pp. 191-197
-
-
Kruger, S.1
Engel, C.2
Bier, A.3
-
90
-
-
39649101283
-
Aurora-A and Cyclin D1 polymorphisms and the age of onset of colorectal cancer in hereditary nonpolyposis colorectal cancer
-
Talseth B.A., Ashton K.A., Meldrum C., et al. Aurora-A and Cyclin D1 polymorphisms and the age of onset of colorectal cancer in hereditary nonpolyposis colorectal cancer. Int J Cancer 122 (2008) 1273-1277
-
(2008)
Int J Cancer
, vol.122
, pp. 1273-1277
-
-
Talseth, B.A.1
Ashton, K.A.2
Meldrum, C.3
-
91
-
-
37349072910
-
Association of familial colorectal cancer with variants in the E-cadherin (CDH1) and cyclin D1 (CCND1) genes
-
Grunhage F., Jungck M., Lamberti C., et al. Association of familial colorectal cancer with variants in the E-cadherin (CDH1) and cyclin D1 (CCND1) genes. Int J Colorectal Dis 23 (2008) 147-154
-
(2008)
Int J Colorectal Dis
, vol.23
, pp. 147-154
-
-
Grunhage, F.1
Jungck, M.2
Lamberti, C.3
-
92
-
-
42549093639
-
The association of cyclin D1 G870A and E-cadherin C-160A polymorphisms with the risk of colorectal cancer in a case control study and meta-analysis
-
Tan X.L., Nieters A., Kropp S., Hoffmeister M., Brenner H., and Chang-Claude J. The association of cyclin D1 G870A and E-cadherin C-160A polymorphisms with the risk of colorectal cancer in a case control study and meta-analysis. Int J Cancer 122 (2008) 2573-2580
-
(2008)
Int J Cancer
, vol.122
, pp. 2573-2580
-
-
Tan, X.L.1
Nieters, A.2
Kropp, S.3
Hoffmeister, M.4
Brenner, H.5
Chang-Claude, J.6
-
93
-
-
34547121725
-
A common genetic risk factor for colorectal and prostate cancer
-
Haiman C.A., Le Marchand L., Yamamato J., et al. A common genetic risk factor for colorectal and prostate cancer. Nat Genet 39 (2007) 954-956
-
(2007)
Nat Genet
, vol.39
, pp. 954-956
-
-
Haiman, C.A.1
Le Marchand, L.2
Yamamato, J.3
-
94
-
-
34547498546
-
A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21
-
Tomlinson I., Webb W., Carvajal-Carmona L., et al. A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21. Nat Genet 39 (2007) 984-988
-
(2007)
Nat Genet
, vol.39
, pp. 984-988
-
-
Tomlinson, I.1
Webb, W.2
Carvajal-Carmona, L.3
-
95
-
-
34547092701
-
Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24
-
Zanke B.W., Greenwood C.M., Rangrej J., et al. Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24. Nat Genet 39 (2007) 989-994
-
(2007)
Nat Genet
, vol.39
, pp. 989-994
-
-
Zanke, B.W.1
Greenwood, C.M.2
Rangrej, J.3
-
96
-
-
35648937584
-
A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk
-
Broderick P., Carvajal-Carmona L., Pittman A.M., et al. A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk. Nat Genet 39 (2007) 1315-1317
-
(2007)
Nat Genet
, vol.39
, pp. 1315-1317
-
-
Broderick, P.1
Carvajal-Carmona, L.2
Pittman, A.M.3
-
97
-
-
42649136554
-
A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3
-
Tomlinson I.P.M., Webb E., Carvajal-Carmona L., et al. A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3. Nat Genet 40 (2008) 623-630
-
(2008)
Nat Genet
, vol.40
, pp. 623-630
-
-
Tomlinson, I.P.M.1
Webb, E.2
Carvajal-Carmona, L.3
-
98
-
-
42649124305
-
Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21
-
Tenesa A., Farrington S.M., Prendergast J.G.D., et al. Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21. Nat Genet 40 (2008) 631-637
-
(2008)
Nat Genet
, vol.40
, pp. 631-637
-
-
Tenesa, A.1
Farrington, S.M.2
Prendergast, J.G.D.3
-
99
-
-
0026894053
-
Somatic mutations of the APC gene in colorectal tumors: mutation cluster region in the APC gene
-
Miyoshi Y., Nagase H., Ando H., et al. Somatic mutations of the APC gene in colorectal tumors: mutation cluster region in the APC gene. Hum Mol Genet 1 (1992) 229-233
-
(1992)
Hum Mol Genet
, vol.1
, pp. 229-233
-
-
Miyoshi, Y.1
Nagase, H.2
Ando, H.3
-
100
-
-
0034644526
-
Linking colorectal cancer to Wnt signaling
-
Bienz M., and Clevers H. Linking colorectal cancer to Wnt signaling. Cell 103 (2000) 311-320
-
(2000)
Cell
, vol.103
, pp. 311-320
-
-
Bienz, M.1
Clevers, H.2
-
101
-
-
0042941629
-
BRAF and KRAS mutations in colorectal hyperplastic polyps and serrated adenomas
-
Chan T.L., Zhao W., Cancer Genome Project, Leung S.Y., and Yuen S.T. BRAF and KRAS mutations in colorectal hyperplastic polyps and serrated adenomas. Cancer Res 63 (2003) 4878-4881
-
(2003)
Cancer Res
, vol.63
, pp. 4878-4881
-
-
Chan, T.L.1
Zhao, W.2
Cancer Genome Project3
Leung, S.Y.4
Yuen, S.T.5
-
102
-
-
33750682008
-
High prevalence of sessile serrated adenomas with BRAF mutations: a prospective study of patients undergoing colonoscopy
-
Spring K.J., Zhao Z.Z., Karamatic R., et al. High prevalence of sessile serrated adenomas with BRAF mutations: a prospective study of patients undergoing colonoscopy. Gastroenterology 131 (2006) 1400-1407
-
(2006)
Gastroenterology
, vol.131
, pp. 1400-1407
-
-
Spring, K.J.1
Zhao, Z.Z.2
Karamatic, R.3
-
103
-
-
0037372340
-
Frequent CpG island methylation in serrated adenomas of the colorectum
-
Park S.J., Rashid A., Lee J.H., Kim S.G., Hamilton S.R., and Wu T.T. Frequent CpG island methylation in serrated adenomas of the colorectum. Am J Pathol 162 (2003) 815-822
-
(2003)
Am J Pathol
, vol.162
, pp. 815-822
-
-
Park, S.J.1
Rashid, A.2
Lee, J.H.3
Kim, S.G.4
Hamilton, S.R.5
Wu, T.T.6
-
104
-
-
0037408432
-
Germline mutations but not somatic changes at the MYH locus contribute to the pathogenesis of unselected colorectal cancers
-
Halford S.E.R., Rowan A.J., Lipton L., et al. Germline mutations but not somatic changes at the MYH locus contribute to the pathogenesis of unselected colorectal cancers. Am J Pathol 162 (2003) 1545-1548
-
(2003)
Am J Pathol
, vol.162
, pp. 1545-1548
-
-
Halford, S.E.R.1
Rowan, A.J.2
Lipton, L.3
-
105
-
-
33750433538
-
The role of MYH and microsatellite instability in the development of sporadic colorectal cancer
-
Colebatch A., Hitchins M., Williams R., et al. The role of MYH and microsatellite instability in the development of sporadic colorectal cancer. Br J Cancer 95 (2006) 1239-1243
-
(2006)
Br J Cancer
, vol.95
, pp. 1239-1243
-
-
Colebatch, A.1
Hitchins, M.2
Williams, R.3
-
106
-
-
33747893402
-
Peroxisome proliferator-activated receptor (PPAR)γ gene polymorphisms and colorectal cancer risk among Chinese in Singapore
-
Koh W.P., Yuan J.M., Van Den Berg D., Ingles S.A., and Yu M.C. Peroxisome proliferator-activated receptor (PPAR)γ gene polymorphisms and colorectal cancer risk among Chinese in Singapore. Carcinogenesis 27 (2006) 1979-2802
-
(2006)
Carcinogenesis
, vol.27
, pp. 1979-2802
-
-
Koh, W.P.1
Yuan, J.M.2
Van Den Berg, D.3
Ingles, S.A.4
Yu, M.C.5
-
108
-
-
28644446615
-
Polymorphisms in the reduced folate carrier, thymidylate synthase, or methionine synthase and risk of colon cancer
-
Ulrich C.M., Curtin K., Potter J.D., Bigler J., Caan B., and Slattery M.L. Polymorphisms in the reduced folate carrier, thymidylate synthase, or methionine synthase and risk of colon cancer. Cancer Epidemiol Biomarkers Prev 14 (2005) 2509-2516
-
(2005)
Cancer Epidemiol Biomarkers Prev
, vol.14
, pp. 2509-2516
-
-
Ulrich, C.M.1
Curtin, K.2
Potter, J.D.3
Bigler, J.4
Caan, B.5
Slattery, M.L.6
-
109
-
-
33845608177
-
Dietary factors and biomarkers involved in the methylenetetrahydrofolate reductase genotype-colorectal adenoma pathway
-
Martinez M.E., Thompson P., Jacobs E.T., et al. Dietary factors and biomarkers involved in the methylenetetrahydrofolate reductase genotype-colorectal adenoma pathway. Gastroenterology 131 (2006) 1706-1716
-
(2006)
Gastroenterology
, vol.131
, pp. 1706-1716
-
-
Martinez, M.E.1
Thompson, P.2
Jacobs, E.T.3
-
110
-
-
33845869785
-
Different roles of MTHFR C677T and A1298C polymorhphisms in colorectal adenoma and colorectal cancer: a metaanalysis
-
Huang Y., Han S., Li Y., Mao Y., and Xie Y. Different roles of MTHFR C677T and A1298C polymorhphisms in colorectal adenoma and colorectal cancer: a metaanalysis. J Hum Genet 52 (2007) 73-85
-
(2007)
J Hum Genet
, vol.52
, pp. 73-85
-
-
Huang, Y.1
Han, S.2
Li, Y.3
Mao, Y.4
Xie, Y.5
-
111
-
-
34548178346
-
Genetic polymorhphisms in onecarbon metabolism: associations with CpG island methylator phenotype (CIMP) in colon cancer and the modifying effects of diet
-
Curtin K., Slattery M.L., Ulrich C.M., et al. Genetic polymorhphisms in onecarbon metabolism: associations with CpG island methylator phenotype (CIMP) in colon cancer and the modifying effects of diet. Carcinogenesis 28 (2007) 1672-1679
-
(2007)
Carcinogenesis
, vol.28
, pp. 1672-1679
-
-
Curtin, K.1
Slattery, M.L.2
Ulrich, C.M.3
-
112
-
-
33845353379
-
The effect of the cyclin D1 (CCND1) A870G polymorphism on colorectal cancer risk is modified by glutathione-S-transferase polymorphisms and isothiocyanate intake in Singapore Chinese Health Study
-
Probst-Hensch N.M., Sun C.L., Van Den Berg D., Ceschi M., Koh W.P., and Yu M.C. The effect of the cyclin D1 (CCND1) A870G polymorphism on colorectal cancer risk is modified by glutathione-S-transferase polymorphisms and isothiocyanate intake in Singapore Chinese Health Study. Carcinogenesis 27 (2006) 2475-2482
-
(2006)
Carcinogenesis
, vol.27
, pp. 2475-2482
-
-
Probst-Hensch, N.M.1
Sun, C.L.2
Van Den Berg, D.3
Ceschi, M.4
Koh, W.P.5
Yu, M.C.6
-
113
-
-
33746342180
-
Overexpression of RB1 transcript is significantly correlated with 13q14 allelic imbalance in colorectal carcinomas
-
Lai P.S., Cheah P.Y., Kadam P., et al. Overexpression of RB1 transcript is significantly correlated with 13q14 allelic imbalance in colorectal carcinomas. Int J Cancer 19 (2006) 1061-1066
-
(2006)
Int J Cancer
, vol.19
, pp. 1061-1066
-
-
Lai, P.S.1
Cheah, P.Y.2
Kadam, P.3
-
114
-
-
34548842228
-
Overexpression of FLIPL is an independent marker of poor prognosis in colorectal cancer patients
-
Ullenhag G.J., Mukherjee A., Watson N.F., Al-Attar A.H., Scholefield J.H., and Durrant L.G. Overexpression of FLIPL is an independent marker of poor prognosis in colorectal cancer patients. Clin Cancer Res 13 (2007) 5070-5075
-
(2007)
Clin Cancer Res
, vol.13
, pp. 5070-5075
-
-
Ullenhag, G.J.1
Mukherjee, A.2
Watson, N.F.3
Al-Attar, A.H.4
Scholefield, J.H.5
Durrant, L.G.6
-
115
-
-
38949148986
-
HDAC3 overexpression and colon cancer cell proliferation and differentiation
-
Spurling C.C., Godman C.A., Noonan E.J., Rasmussen T.P., Rosenberg D.W., and Giardina C. HDAC3 overexpression and colon cancer cell proliferation and differentiation. Mol Carcinog 47 (2008) 137-147
-
(2008)
Mol Carcinog
, vol.47
, pp. 137-147
-
-
Spurling, C.C.1
Godman, C.A.2
Noonan, E.J.3
Rasmussen, T.P.4
Rosenberg, D.W.5
Giardina, C.6
-
116
-
-
38749123410
-
Overexpression of ID-1 protein is a marker in colorectal cancer progression
-
Zhao Z.R., Zhang Z.Y., Zhang H., Jiang L., Wang M.W., and Sun X.F. Overexpression of ID-1 protein is a marker in colorectal cancer progression. Oncol Rep 19 (2008) 419-424
-
(2008)
Oncol Rep
, vol.19
, pp. 419-424
-
-
Zhao, Z.R.1
Zhang, Z.Y.2
Zhang, H.3
Jiang, L.4
Wang, M.W.5
Sun, X.F.6
-
117
-
-
33947202248
-
A susceptibility gene-set for early onset colorectal cancer that integrates diverse signaling pathways-implication for tumorigenesis
-
Hong Y., Ho K.S., Eu K.W., and Cheah P.Y. A susceptibility gene-set for early onset colorectal cancer that integrates diverse signaling pathways-implication for tumorigenesis. Clin Cancer Res 13 (2007) 1107-1114
-
(2007)
Clin Cancer Res
, vol.13
, pp. 1107-1114
-
-
Hong, Y.1
Ho, K.S.2
Eu, K.W.3
Cheah, P.Y.4
-
118
-
-
2442684455
-
Gene expression profiles and molecular markers to predict recurrence of Dukes'B colon cancer
-
Wang Y., Jatkoe T., Zhang Y., et al. Gene expression profiles and molecular markers to predict recurrence of Dukes'B colon cancer. J Clin Oncol 22 (2004) 1564-1571
-
(2004)
J Clin Oncol
, vol.22
, pp. 1564-1571
-
-
Wang, Y.1
Jatkoe, T.2
Zhang, Y.3
-
119
-
-
2942668475
-
Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration
-
Sansom O.J., Reed K.R., Hayes A.J., et al. Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration. Genes Dev 18 (2004) 1385-1390
-
(2004)
Genes Dev
, vol.18
, pp. 1385-1390
-
-
Sansom, O.J.1
Reed, K.R.2
Hayes, A.J.3
-
120
-
-
0034180948
-
Update of genetics in colorectal carcinomas: genomic instability and somatic evolution
-
Cheah P.Y., Eu K.W., and Seow-Choen F. Update of genetics in colorectal carcinomas: genomic instability and somatic evolution. Annals Acad Med Singapore 29 (2000) 331-336
-
(2000)
Annals Acad Med Singapore
, vol.29
, pp. 331-336
-
-
Cheah, P.Y.1
Eu, K.W.2
Seow-Choen, F.3
-
121
-
-
0031908348
-
Defects in mismatch repair occur after APC mutations in the pathogenesis of sporadic colorectal tumors
-
Homfray T.F.R., Cottrell S.E., Ilyas M., et al. Defects in mismatch repair occur after APC mutations in the pathogenesis of sporadic colorectal tumors. Hum Mut 11 (1998) 114-120
-
(1998)
Hum Mut
, vol.11
, pp. 114-120
-
-
Homfray, T.F.R.1
Cottrell, S.E.2
Ilyas, M.3
-
122
-
-
0037168610
-
Analysis of chromosomal instability in human colorectal adenomas with two mutational hits at APC
-
Siber O.M., Heinimann K., Gorman P., et al. Analysis of chromosomal instability in human colorectal adenomas with two mutational hits at APC. Proc Natl Acad Sci USA 99 (2002) 16910-16915
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 16910-16915
-
-
Siber, O.M.1
Heinimann, K.2
Gorman, P.3
-
123
-
-
0030054532
-
Molecular nature of colon tumors in hereditary nonpolyposis colon cancer, familial polyposis, and sporadic colon cancer
-
Konishi M., Kikuchi-Yanoshita R., Tanaka K., et al. Molecular nature of colon tumors in hereditary nonpolyposis colon cancer, familial polyposis, and sporadic colon cancer. Gastroenterology 111 (1996) 307-317
-
(1996)
Gastroenterology
, vol.111
, pp. 307-317
-
-
Konishi, M.1
Kikuchi-Yanoshita, R.2
Tanaka, K.3
-
124
-
-
0033568145
-
Frequent mutation of β-catenin and APC genes in primary colorectal tumors from patients with hereditary nonpolyposis colorectal cancer
-
Miyaki M., Iijima T., Kimura J., et al. Frequent mutation of β-catenin and APC genes in primary colorectal tumors from patients with hereditary nonpolyposis colorectal cancer. Cancer Res 59 (1999) 4506-4509
-
(1999)
Cancer Res
, vol.59
, pp. 4506-4509
-
-
Miyaki, M.1
Iijima, T.2
Kimura, J.3
-
125
-
-
6944224156
-
BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-β-catenin signaling
-
He X.C., Zhang J., Tong W.G., et al. BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-β-catenin signaling. Nat Genet 36 (2004) 1117-1121
-
(2004)
Nat Genet
, vol.36
, pp. 1117-1121
-
-
He, X.C.1
Zhang, J.2
Tong, W.G.3
-
126
-
-
6944244098
-
Linking pathways in colorectal cancer
-
van den Brink G.R. Linking pathways in colorectal cancer. Nat Genet 36 (2004) 1038-1039
-
(2004)
Nat Genet
, vol.36
, pp. 1038-1039
-
-
van den Brink, G.R.1
-
127
-
-
0037444213
-
BMP2 exposure results in decreased PTEN protein degradation and increased PTEN levels
-
Waite K.A., and Eng C. BMP2 exposure results in decreased PTEN protein degradation and increased PTEN levels. Hum Mol Genet 12 (2003) 679-684
-
(2003)
Hum Mol Genet
, vol.12
, pp. 679-684
-
-
Waite, K.A.1
Eng, C.2
-
129
-
-
26444610333
-
LKB1 interacts with and phosphorylates PTEN: a functional link between two proteins involved in cancer predisposing syndromes
-
Mohenni H., Lin-Marq N., Buchet-Poyau K., et al. LKB1 interacts with and phosphorylates PTEN: a functional link between two proteins involved in cancer predisposing syndromes. Hum Mol Genet 14 (2005) 2209-2219
-
(2005)
Hum Mol Genet
, vol.14
, pp. 2209-2219
-
-
Mohenni, H.1
Lin-Marq, N.2
Buchet-Poyau, K.3
-
130
-
-
18744399860
-
Peutz-Jeghers LKB1 mutants fail to activate GSK-3beta, preventing it from inhibiting Wnt signaling
-
Lin-Marq N., Borel C., and Antonarakis S.E. Peutz-Jeghers LKB1 mutants fail to activate GSK-3beta, preventing it from inhibiting Wnt signaling. Mol Genet Genomics 273 (2005) 184-196
-
(2005)
Mol Genet Genomics
, vol.273
, pp. 184-196
-
-
Lin-Marq, N.1
Borel, C.2
Antonarakis, S.E.3
-
131
-
-
29244431680
-
Mucosal prolapse in the pathogenesis of Peutz-Jeghers polyposis
-
Jansen M., de Leng W.W.J., Baas A.F., et al. Mucosal prolapse in the pathogenesis of Peutz-Jeghers polyposis. Gut 55 (2006) 1-5
-
(2006)
Gut
, vol.55
, pp. 1-5
-
-
Jansen, M.1
de Leng, W.W.J.2
Baas, A.F.3
-
132
-
-
27144510277
-
Stem cells, asymmetric division and cancer
-
Clevers H. Stem cells, asymmetric division and cancer. Nat Genet 37 (2005) 1027-1028
-
(2005)
Nat Genet
, vol.37
, pp. 1027-1028
-
-
Clevers, H.1
-
133
-
-
37549000073
-
Flat colorectal cancers are genetically determined and progress to invasion without going through a polypoid stage
-
Uronis J.M., Herfarth H.H., Rubinas T.C., Bissahoyo A.C., Hanlon K., and Threadgill D.W. Flat colorectal cancers are genetically determined and progress to invasion without going through a polypoid stage. Cancer Res 67 (2007) 11594-11600
-
(2007)
Cancer Res
, vol.67
, pp. 11594-11600
-
-
Uronis, J.M.1
Herfarth, H.H.2
Rubinas, T.C.3
Bissahoyo, A.C.4
Hanlon, K.5
Threadgill, D.W.6
-
134
-
-
0034118420
-
Distinction between dysplasia associated lesion or mass (DALM) and adenoma in patients with ulcertive colitis
-
Fogt F., Urbanski S.J., Sanders M.E., et al. Distinction between dysplasia associated lesion or mass (DALM) and adenoma in patients with ulcertive colitis. Hum Pathol 31 (2000) 288-291
-
(2000)
Hum Pathol
, vol.31
, pp. 288-291
-
-
Fogt, F.1
Urbanski, S.J.2
Sanders, M.E.3
-
135
-
-
0035674997
-
Tissue microarray anlaysis of beta-catenin in colorectal cancer shows nuclear phosphobeta-catenin is associated with a better prognosis
-
Chung G.G., Provost E., Kielhorn E.P., Charette L.A., Smith B.L., and Rimm D.L. Tissue microarray anlaysis of beta-catenin in colorectal cancer shows nuclear phosphobeta-catenin is associated with a better prognosis. Clin Cancer Res 7 (2001) 4013-4020
-
(2001)
Clin Cancer Res
, vol.7
, pp. 4013-4020
-
-
Chung, G.G.1
Provost, E.2
Kielhorn, E.P.3
Charette, L.A.4
Smith, B.L.5
Rimm, D.L.6
-
136
-
-
0037114729
-
A survival stratification model of human colorectal carcinomas with β-catenin and p27kip1
-
Cheah P.Y., Choo P.H., Yao J., Eu K.W., and Seow-Choen F. A survival stratification model of human colorectal carcinomas with β-catenin and p27kip1. Cancer 95 (2002) 2479-2486
-
(2002)
Cancer
, vol.95
, pp. 2479-2486
-
-
Cheah, P.Y.1
Choo, P.H.2
Yao, J.3
Eu, K.W.4
Seow-Choen, F.5
-
137
-
-
11144355980
-
MUC1 and nuclear beta-catenin are coexpressed at the invasion front of colorectal carcinomas and are both correlated with tumor prognosis
-
Baldus S.E., Monig S.P., Huxel S., et al. MUC1 and nuclear beta-catenin are coexpressed at the invasion front of colorectal carcinomas and are both correlated with tumor prognosis. Clin Cancer Res 10 (2004) 2790-2796
-
(2004)
Clin Cancer Res
, vol.10
, pp. 2790-2796
-
-
Baldus, S.E.1
Monig, S.P.2
Huxel, S.3
-
138
-
-
34548191532
-
Who should be sent for genetic testing in hereditary nonpolyposis colorectal cancer syndromes?
-
Lynch H.T., Boland C.R., Rodriguez-Bigas M.A., Amos C., Lynch J.F., and Lynch P.M. Who should be sent for genetic testing in hereditary nonpolyposis colorectal cancer syndromes?. J Clin Oncol 25 (2007) 3534-3542
-
(2007)
J Clin Oncol
, vol.25
, pp. 3534-3542
-
-
Lynch, H.T.1
Boland, C.R.2
Rodriguez-Bigas, M.A.3
Amos, C.4
Lynch, J.F.5
Lynch, P.M.6
-
139
-
-
34250715384
-
Guidelines for the clinical management of Lynch syndrome (hereditary non-polyposis cancer)
-
Vasen H.F., Moslein G., Alonso A., et al. Guidelines for the clinical management of Lynch syndrome (hereditary non-polyposis cancer). J Med Genet 44 (2007) 353-362
-
(2007)
J Med Genet
, vol.44
, pp. 353-362
-
-
Vasen, H.F.1
Moslein, G.2
Alonso, A.3
-
140
-
-
42549165647
-
Guidelines for the clinical management of familial adenomatous polyposis (FAP)
-
Vasen H.F., Moslein G., Alonso A., et al. Guidelines for the clinical management of familial adenomatous polyposis (FAP). Gut 57 (2008) 704-713
-
(2008)
Gut
, vol.57
, pp. 704-713
-
-
Vasen, H.F.1
Moslein, G.2
Alonso, A.3
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