Common variant in 6q26-q27 is associated with distal colon cancer in an Asian population

Gut

Volumn 60, Issue 6, 2011, Pages 799-805

  Cui, R ^a   Okada, Y ^a   Jang, S G ^b   Ku, J L ^b   Park, J G ^b   Kamatani, Y ^a   Hosono, N ^c   Tsunoda, T ^c   Kumar, V ^a   Tanikawa, C ^a   Kamatani, N ^c   Yamada, R ^a   Kubo, M ^c   Nakamura, Y ^a,c   Matsuda, Koichi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b Seoul National University College of Medicine   (South Korea)

^c INST OF PHYS AND CHEMICAL RESEARCH   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL CONSUMPTION; ARTICLE; ASIAN; CANCER RISK; CANCER SUSCEPTIBILITY; CAUCASIAN; COLON CANCER; COLON CARCINOGENESIS; CONTROLLED STUDY; ENVIRONMENTAL FACTOR; EXON; GENE LOCUS; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HEREDITY; HUMAN; INTRON; JAPANESE; MAJOR CLINICAL STUDY; POPULATION BASED CASE CONTROL STUDY; PRIORITY JOURNAL; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM; TUMOR LOCALIZATION;

ADULT; AGED; CASE-CONTROL STUDIES; CHROMOSOMES, HUMAN, PAIR 6; COLORECTAL NEOPLASMS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; JAPAN; LINKAGE DISEQUILIBRIUM; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 79955860324     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gut.2010.215947     Document Type: Article

References (39)

1. Jemal A, Siegel R, Ward E, et al. Cancer statistics, 2008. CA Cancer J Clin 2008;58:71-96.
2. Johns LE, Houlston RS. A systematic review and meta-analysis of familial colorectal cancer risk. Am J Gastroenterol 2001;96:2992-3003. (Pubitemid 32959544)
3. Carstensen B, Soll-Johanning H, Villadsen E, et al. Familial aggregation of colorectal cancer in the general population. Int J Cancer 1996;68:428-35. (Pubitemid 26414495)
4. Fuchs CS, Giovannucci EL, Colditz GA, et al. A prospective study of family history and the risk of colorectal cancer. N Engl J Med 1994;331:1669-74. (Pubitemid 24373618)
5. Slattery ML, Kerber RA. Family history of cancer and colon cancer risk: the Utah Population Database. J Natl Cancer Inst 1994;86:1618-26. (Pubitemid 24336348)
6. Lichtenstein P, Holm NV, Verkasalo PK, et al. Environmental and heritable factors in the causation of cancer - analyses of cohorts of twins from Sweden, Denmark, and Finland. N Engl J Med 2000;343:78-85. (Pubitemid 30451850)
7. Aaltonen L, Johns L, Jarvinen H, et al. Explaining the familial colorectal cancer risk associated with mismatch repair (MMR)-deficient and MMR-stable tumors. Clin Cancer Res 2007;13:356-61. (Pubitemid 46121890)
8. Tomlinson I, Webb E, Carvajal-Carmona L, et al. A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21. Nat Genet 2007;39:984-8. (Pubitemid 47185182)
9. Zanke BW, Greenwood CM, Rangrej J, et al. Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24. Nat Genet 2007;39:989-94. (Pubitemid 47185183)
10. Tomlinson IP, Webb E, Carvajal-Carmona L, et al. A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3. Nat Genet 2008;40:623-30. (Pubitemid 351601204)
11. Tenesa A, Farrington SM, Prendergast JG, et al. Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21. Nat Genet 2008;40:631-7. (Pubitemid 351601219)
12. Jaeger E, Webb E, Howarth K, et al. Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13.3 influence colorectal cancer risk. Nat Genet 2008;40:26-8.
13. Broderick P, Carvajal-Carmona L, Pittman AM, et al. A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk. Nat Genet 2007;39:1315-17. (Pubitemid 350034998)
14. Houlston RS, Webb E, Broderick P, et al. Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer. Nat Genet 2008;40:1426-35.
15. Cui R, Kamatani Y, Takahashi A, et al. Functional variants in ADH1B and ALDH2 coupled with alcohol and smoking synergistically enhance esophageal cancer risk. Gastroenterology 2009;137:1768-75.
16. Ohnishi Y, Tanaka T, Ozaki K, et al. A high-throughput SNP typing system for genome-wide association studies. J Hum Genet 2001;46:471-7. (Pubitemid 32744120)
17. Thygesen LC, Wu K, Gronbaek M, et al. Alcohol intake and colorectal cancer: a comparison of approaches for including repeated measures of alcohol consumption. Epidemiology 2008;19:258-64. (Pubitemid 351253013)
18. Yamaguchi-Kabata Y, Nakazono K, Takahashi A, et al. Japanese population structure, based on SNP genotypes from 7003 individuals compared to other ethnic groups: effects on population-based association studies. Am J Hum Genet 2008;83:445-56.
19. Freedman ML, Reich D, Penney KL, et al. Assessing the impact of population stratification on genetic association studies. Nat Genet 2004;36:388-93. (Pubitemid 38437262)
20. Cleary SP, Cotterchio M, Shi E, et al. Cigarette smoking, genetic variants in carcinogen-metabolizing enzymes, and colorectal cancer risk. Am J Epidemiol 2010;172:1000-14.
21. Gonzalez EC, Roetzheim RG, Ferrante JM, et al. Predictors of proximal vs. distal colorectal cancers. Dis Colon Rectum 2001;44:251-8. (Pubitemid 32173775)
22. Kune S, Kune GA, Watson L. The Melbourne colorectal cancer study: incidence findings by age, sex, site, migrants and religion. Int J Epidemiol 1986;15:483-93. (Pubitemid 17229482)
23. Bufill JA. Colorectal cancer: evidence for distinct genetic categories based on proximal or distal tumor location. Ann Intern Med 1990;113:779-88. (Pubitemid 20369667)
24. Lynch HT, Smyrk TC. Classification of familial adenomatous polyposis: a diagnostic nightmare. Am J Hum Genet 1998;62:1288-9. (Pubitemid 28307097)
25. Lynch HT, Watson P, Lanspa SJ, et al. Natural history of colorectal cancer in hereditary nonpolyposis colorectal cancer (Lynch syndromes I and II). Dis Colon Rectum 1988;31:439-44.
26. Hamelin R, Laurent-Puig P, Olschwang S, et al. Association of p53 mutations with short survival in colorectal cancer. Gastroenterology 1994;106:42-8. (Pubitemid 24011863)
27. Minami Y, Nishino Y, Tsubono Y, et al. Increase of colon and rectal cancer incidence rates in Japan: trends in incidence rates in Miyagi Prefecture, 1959-1997. J Epidemiol 2006;16:240-8.
28. Sakamoto K, Machi J, Prygrocki M, et al. Comparison of characteristics and survival of colorectal cancer between Japanese-Americans in Hawaii and native Japanese in Japan. Dis Colon Rectum 2006;49:50-7. (Pubitemid 41830655)
29. Eeles RA, Kote-Jarai Z, Giles GG, et al. Multiple newly identified loci associated with prostate cancer susceptibility. Nat Genet 2008;40:316-21. (Pubitemid 351311772)
30. Kekuda R, Prasad PD, Wu X, et al. Cloning and functional characterization of a potential-sensitive, polyspecific organic cation transporter (OCT3) most abundantly expressed in placenta. J Biol Chem 1998;273:15971-9. (Pubitemid 28311362)
31. Inui KI, Masuda S, Saito H. Cellular and molecular aspects of drug transport in the kidney. Kidney Int 2000;58:944-58.
32. Shnitsar V, Eckardt R, Gupta S, et al. Expression of human organic cation transporter 3 in kidney carcinoma cell lines increases chemosensitivity to melphalan, irinotecan, and vincristine. Cancer Res 2009;69:1494-501.
33. Yokoo S, Masuda S, Yonezawa A, et al. Significance of organic cation transporter 3 (SLC22A3) expression for the cytotoxic effect of oxaliplatin in colorectal cancer. Drug Metab Dispos 2008;36:2299-306.
34. Reisser D, Pance A, Jeannin JF. Mechanisms of the antitumoral effect of lipid A. Bioessays 2002;24:284-9. (Pubitemid 34248695)
35. Yasuda M, Nishizawa T, Ohigashi H, et al. Linoleic acid metabolite suppresses skin inflammation and tumor promotion in mice: possible roles of programmed cell death 4 induction. Carcinogenesis 2009;30:1209-16.
36. Poynter JN, Haile RW, Siegmund KD, et al. Associations between smoking, alcohol consumption, and colorectal cancer, overall and by tumor microsatellite instability status. Cancer Epidemiol Biomarkers Prev 2009;18:2745-50.
37. Bongaerts BW, van den Brandt PA, Goldbohm RA, et al. Alcohol consumption, type of alcoholic beverage and risk of colorectal cancer at specific subsites. Int J Cancer 2008;123:2411-17.
38. Takeshita T, Morimoto K, Mao X, et al. Characterization of the three genotypes of low Km aldehyde dehydrogenase in a Japanese population. Hum Genet 1994;94:217-23. (Pubitemid 24262196)
39. Research Group for Population-based Cancer Registration in Japan. Cancer incidence and incidence rates in Japan in 1997: estimates based on data from 12 population-based cancer registries. Jpn J Clin Oncol 2002;32:318-22.