메뉴 건너뛰기




Volumn 40, Issue 5, 2008, Pages 623-630

A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3

(75)  Tomlinson, Ian P M a   Webb, Emily b   Carvajal Carmona, Luis a   Broderick, Peter b   Howarth, Kimberley a   Pittman, Alan M b   Spain, Sarah a   Lubbe, Steven b   Walther, Axel a   Sullivan, Kate b   Jaeger, Emma a   Fielding, Sarah b   Rowan, Andrew a   Vijayakrishnan, Jayaram b   Domingo, Enric a   Chandler, Ian b   Kemp, Zoe a   Qureshi, Mobshra b   Farrington, Susan M c   Tenesa, Albert c   more..


Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ALLELE; ARTICLE; CANCER RISK; CHROMOSOME 10P; CHROMOSOME 15Q; CHROMOSOME 18Q; CHROMOSOME 8Q; COLORECTAL ADENOMA; COLORECTAL CANCER; CONTROLLED STUDY; EIF3H GENE; FAMILIAL CANCER; FEMALE; GENE AMPLIFICATION; GENE EXPRESSION; GENE IDENTIFICATION; GENE LOCATION; GENE LOCUS; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENOME ANALYSIS; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; MUTATOR GENE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 42649136554     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.111     Document Type: Article
Times cited : (491)

References (22)
  • 1
    • 33846332027 scopus 로고    scopus 로고
    • Explaining the familial colorectal cancer risk associated with mismatch repair (MMR)-deficient and MMR-stable tumors
    • Aaltonen, L., Johns, L., Jarvinen, H., Mecklin, J.P. & Houlston, R. Explaining the familial colorectal cancer risk associated with mismatch repair (MMR)-deficient and MMR-stable tumors. Clin. Cancer Res. 13, 356-361 (2007).
    • (2007) Clin. Cancer Res , vol.13 , pp. 356-361
    • Aaltonen, L.1    Johns, L.2    Jarvinen, H.3    Mecklin, J.P.4    Houlston, R.5
  • 2
    • 34547498546 scopus 로고    scopus 로고
    • A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21
    • Tomlinson, I. et al. A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21. Nat. Genet. 39, 984-988 (2007).
    • (2007) Nat. Genet , vol.39 , pp. 984-988
    • Tomlinson, I.1
  • 3
    • 35648937584 scopus 로고    scopus 로고
    • A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk
    • Broderick, P. et al. A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk. Nat. Genet. 39, 1315-1317 (2007).
    • (2007) Nat. Genet , vol.39 , pp. 1315-1317
    • Broderick, P.1
  • 4
    • 37549072226 scopus 로고    scopus 로고
    • Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13.3 influence colorectal cancer risk
    • Jaeger, E. et al. Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13.3 influence colorectal cancer risk. Nat. Genet. 40, 26-28 (2008).
    • (2008) Nat. Genet , vol.40 , pp. 26-28
    • Jaeger, E.1
  • 5
    • 0142063079 scopus 로고    scopus 로고
    • Polygenic inheritance of breast cancer: Implications for design of association studies
    • Antoniou, A.C. & Easton, D.F. Polygenic inheritance of breast cancer: implications for design of association studies. Genet. Epidemiol. 25, 190-202 (2003).
    • (2003) Genet. Epidemiol , vol.25 , pp. 190-202
    • Antoniou, A.C.1    Easton, D.F.2
  • 6
    • 0038823932 scopus 로고    scopus 로고
    • The future of association studies of common cancers
    • Houlston, R.S. & Peto, J. The future of association studies of common cancers. Hum. Genet. 112, 434-435 (2003).
    • (2003) Hum. Genet , vol.112 , pp. 434-435
    • Houlston, R.S.1    Peto, J.2
  • 7
    • 27644546712 scopus 로고    scopus 로고
    • Population structure, differential bias and genomic control in a large-scale, case-control association study
    • Clayton, D.G. et al. Population structure, differential bias and genomic control in a large-scale, case-control association study. Nat. Genet. 37, 1243-1246 (2005).
    • (2005) Nat. Genet , vol.37 , pp. 1243-1246
    • Clayton, D.G.1
  • 8
    • 0037730140 scopus 로고    scopus 로고
    • An ancestral Ashkenazi haplotype at the HMPS/CRAC1 locus on 15q13-q14 is associated with hereditary mixed polyposis syndrome
    • Jaeger, E.E. et al. An ancestral Ashkenazi haplotype at the HMPS/CRAC1 locus on 15q13-q14 is associated with hereditary mixed polyposis syndrome. Am. J. Hum. Genet. 72, 1261-1267 (2003).
    • (2003) Am. J. Hum. Genet , vol.72 , pp. 1261-1267
    • Jaeger, E.E.1
  • 9
    • 24044523235 scopus 로고    scopus 로고
    • Loss of heterozygosity on chromosome 10p14-p15 in colorectal carcinoma
    • Shima, H. et al. Loss of heterozygosity on chromosome 10p14-p15 in colorectal carcinoma. Pathobiology 72, 220-224 (2005).
    • (2005) Pathobiology , vol.72 , pp. 220-224
    • Shima, H.1
  • 10
    • 1942520992 scopus 로고    scopus 로고
    • Expression and copy number analysis of TRPS1, EIF3S3 and MYC genes in breast and prostate cancer
    • Savinainen, K.J. et al. Expression and copy number analysis of TRPS1, EIF3S3 and MYC genes in breast and prostate cancer. Br. J. Cancer 90, 1041-1046 (2004).
    • (2004) Br. J. Cancer , vol.90 , pp. 1041-1046
    • Savinainen, K.J.1
  • 11
    • 0142213943 scopus 로고    scopus 로고
    • PTK2 and EIF3S3 genes may be amplification targets at 8q23-q24 and are associated with large hepatocellular carcinomas
    • Okamoto, H., Yasui, K., Zhao, C., Arii, S. & Inazawa, J. PTK2 and EIF3S3 genes may be amplification targets at 8q23-q24 and are associated with large hepatocellular carcinomas. Hepatology 38, 1242-1249 (2003).
    • (2003) Hepatology , vol.38 , pp. 1242-1249
    • Okamoto, H.1    Yasui, K.2    Zhao, C.3    Arii, S.4    Inazawa, J.5
  • 12
    • 34547092701 scopus 로고    scopus 로고
    • Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24
    • Zanke, B.W. et al. Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24. Nat. Genet. 39, 989-994 (2007).
    • (2007) Nat. Genet , vol.39 , pp. 989-994
    • Zanke, B.W.1
  • 13
    • 34247482327 scopus 로고    scopus 로고
    • Multiple regions within 8q24 independently affect risk for prostate cancer
    • Haiman, C.A. et al. Multiple regions within 8q24 independently affect risk for prostate cancer. Nat. Genet. 39, 638-644 (2007).
    • (2007) Nat. Genet , vol.39 , pp. 638-644
    • Haiman, C.A.1
  • 14
    • 34547121725 scopus 로고    scopus 로고
    • A common genetic risk factor for colorectal and prostate cancer
    • Haiman, C.A. et al. A common genetic risk factor for colorectal and prostate cancer. Nat. Genet. 39, 954-956 (2007).
    • (2007) Nat. Genet , vol.39 , pp. 954-956
    • Haiman, C.A.1
  • 15
    • 0003505985 scopus 로고
    • World Health Organization, World Health Organization, Geneva, Switzerland
    • World Health Organization. International Classification of Diseases, 1975 Revision (World Health Organization, Geneva, Switzerland, 1977).
    • (1977) International Classification of Diseases, 1975 Revision
  • 16
    • 0031938045 scopus 로고    scopus 로고
    • Determination of the replication error phenotype in human tumors without the requirement for matching normal DNA by analysis of mononucleotide repeat microsatellites
    • Zhou, X.P. et al. Determination of the replication error phenotype in human tumors without the requirement for matching normal DNA by analysis of mononucleotide repeat microsatellites. Genes Chromosom. Cancer 21, 101-107 (1998).
    • (1998) Genes Chromosom. Cancer , vol.21 , pp. 101-107
    • Zhou, X.P.1
  • 17
    • 0032534069 scopus 로고    scopus 로고
    • A National Cancer Institute workshop on microsatellite instability for cancer detection and familial predisposition: Development of international criteria for the determination of microsatellite instability in colorectal cancer
    • Boland, C.R. et al. A National Cancer Institute workshop on microsatellite instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res. 58, 5248-5257 (1998).
    • (1998) Cancer Res , vol.58 , pp. 5248-5257
    • Boland, C.R.1
  • 19
    • 0037098199 scopus 로고    scopus 로고
    • Quantifying heterogeneity in a meta-analysis
    • Higgins, J.P. & Thompson, S.G. Quantifying heterogeneity in a meta-analysis. Stat. Med. 21, 1539-1558 (2002).
    • (2002) Stat. Med , vol.21 , pp. 1539-1558
    • Higgins, J.P.1    Thompson, S.G.2
  • 20
    • 33847337318 scopus 로고    scopus 로고
    • A common coding variant in CASP8 is associated with breast cancer risk
    • Cox, A. et al. A common coding variant in CASP8 is associated with breast cancer risk. Nat. Genet. 39, 352-358 (2007).
    • (2007) Nat. Genet , vol.39 , pp. 352-358
    • Cox, A.1
  • 21
    • 0034793635 scopus 로고    scopus 로고
    • A systematic review and meta-analysis of familial colorectal cancer risk
    • Johns, L.E. & Houlston, R.S. A systematic review and meta-analysis of familial colorectal cancer risk. Am. J. Gastroenterol. 96, 2992-3003 (2001).
    • (2001) Am. J. Gastroenterol , vol.96 , pp. 2992-3003
    • Johns, L.E.1    Houlston, R.S.2
  • 22
    • 31744435871 scopus 로고    scopus 로고
    • Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies
    • Skol, A.D., Scott, L.J., Abecasis, G.R. & Boehnke, M. Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies. Nat. Genet. 38, 209-213 (2006).
    • (2006) Nat. Genet , vol.38 , pp. 209-213
    • Skol, A.D.1    Scott, L.J.2    Abecasis, G.R.3    Boehnke, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.